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Human disease related genes
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UMAP gene cluster
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Keyword
Chromosome
1
2
3
4
5
6
7
8
9
10
11
12
13
14
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16
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MT
Unmapped
X
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External id
Variability
Variable
Not variable
Tissue
Any
Adipose tissue
Brain
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Lymphoid tissue
Male glands
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Mouth
Skin
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Stomach 1
Upper respiratory system
Cluster
1 - Brain neurotransmission
2 - Brain neurotransmission
3 - Brain cellular structure
4 - Brain development
5 - Intracellular signalling
6 - Brain uncharacterized
7 - Retinal
8 - Neurohormonal
9 - Testis spermatogenesis
10 - Housekeeping transcription
11 - Testis uncharacterized
12 - Metabolic
13 - Testis sperm
14 - Low abundant uncharacterized
15 - Testis uncharacterized
16 - Aorta uncharacterized
17 - Cilium structure
18 - Low abundant uncharacterized
19 - Housekeeping mitochondrial
20 - Hormonal
21 - Low abundant uncharacterized
22 - Housekeeping transcription
23 - Cilium structure
24 - Low abundant uncharacterized
25 - Low abundant uncharacterized
26 - Low abundant uncharacterized
27 - Low abundant uncharacterized
28 - Housekeeping mitochondrial translation
29 - Male tissue bacterial defense
30 - Housekeeping structural
31 - Housekeeping uncharacterized
32 - Transport
33 - Lens
34 - Prostate uncharacterized
35 - Low abundant uncharacterized
36 - Receptors uncharacterized
37 - Olfactory bulb
38 - Lung and thyroid development
39 - Kidney transport
40 - Testis
41 - Low abundant uncharacterized
42 - Low abundant uncharacterized
43 - Breast uncharacterized
44 - Housekeeping
45 - Thymus uncharacterized
46 - Skeletal muscle contraction
47 - Spleen uncharacterized
48 - Low abundant uncharacterized
49 - Heart contraction
50 - Muscle contraction
51 - Liver and kidney
52 - Housekeeping
53 - Housekeeping mitochondrial
54 - Interferons
55 - Low abundant uncharacterized
56 - Low abundant uncharacterized
57 - Skin
58 - Immune cells
59 - Squamous epithelium
60 - Not detected
61 - Enzymes and secretion
62 - Squamous epithelium
63 - Small intestine
64 - Gastrointestinal
65 - Epithelium
66 - Housekeeping mRNA
67 - Gastrointestinal
68 - Housekeeping protein processing
69 - Housekeeping
70 - Housekeeping
71 - Housekeeping regulation
72 - Digestive and respiratory defense
73 - Housekeeping cell cycle
74 - Extracellular matrix
75 - Housekeeping
76 - Housekeeping regulation
77 - Housekeeping defense
78 - Lymphoid T cells
79 - Lymphoid myeloid
80 - Heart uncharacterized
81 - Vasculature and connective tissue
82 - Lymphoid B cell
83 - Not detected
84 - Epithelium transcription regulation
Tissue group
Any
Adipose tissue
Adrenal gland
Aorta
Bone marrow
Brain
Breast
Cartilage
Cervix
Choroid plexus
Cornea
Ductus deferens
Dura mater
Endometrium
Epididymis
Esophagus
Fallopian tube
Gallbladder
Heart
Kidney
Large intestine
Lens
Liver
Lung
Lymphoid tissue
Male glands
Mesothelial tissue
Mouth
Ovary
Penis
Pineal gland
Pituitary gland
Retina
Salivary gland
Skeletal muscle
Skin
Small intestine
Smooth muscle
Stomach
Synovial tissue
Testis
Thyroid gland
Upper respiratory system
Urinary bladder
Vagus nerve
Category
Tissue enriched
Group enriched
Tissue enhanced
Low tissue specificity
Not detected
Detected in all
Detected in many
Detected in some
Detected in single
Is highest expressed
Brain region
Any
Amygdala
Basal ganglia
Cerebellum
Cerebral cortex
Corpus callosum
Hippocampal formation
Hypothalamus
Midbrain
Olfactory region
Pituitary gland
Pons and medulla
Retina
Spinal cord
Thalamus
Category
Region enriched
Group enriched
Region enhanced
Low region specificity
Not detected
Detected in all
Detected in many
Detected in some
Detected in single
Is highest expressed
Column
Gene
Position
Tissue specific score
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THE PIG PROTEOME
THE PIG ATLAS
TISSUE SPECIFIC PROTEOME
UMAP GENE CLUSTERING
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390 GENES FOUND
Gene
Gene
i
Gene name, if available.
Gene synonym (Human ortholog)
Ensembl gene id
Ensembl gene id (Proteincoding human ortholog)
Gene description
Uniprot accession (Human ortholog)
Chromosome
Chromosome position
Related human disease
RNA category pig
RNA pig tissue group specificity
RNA pig tissue group distribution
RNA pig tissue group specificity score
RNA pig tissue group specific NX
RNA pig brain regional specificity
RNA pig brain regional distribution
RNA pig brain regional specificity score
RNA pig brain regional specific pTPM
Annotation
UMAP cluster
Within tissue variation
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1.
Select data columns:
Gene
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Gene
i
Gene name, if available.
Gene synonym (Human ortholog)
Ensembl gene id
Ensembl gene id (Proteincoding human ortholog)
Gene description
Uniprot accession (Human ortholog)
Chromosome
Chromosome position
Related human disease
RNA category pig
Expand
RNA pig tissue group specificity
RNA pig tissue group distribution
RNA pig tissue group specificity score
RNA pig tissue group specific NX
RNA pig brain regional specificity
RNA pig brain regional distribution
RNA pig brain regional specificity score
RNA pig brain regional specific pTPM
Annotation
Expand
UMAP cluster
Within tissue variation
Pig Tissue RNA
Expand
Abdominal adipose tissue [NX]
Adrenal gland [NX]
Amygdala [NX]
Aorta [NX]
Bone marrow [NX]
Breast [NX]
Bronchus [NX]
Bulbourethral gland [NX]
Caudate [NX]
Cecum [NX]
Cerebellum [NX]
Cervix [NX]
Choroid plexus [NX]
Cingulate cortex [NX]
Colon [NX]
Cornea [NX]
Corpus callosum [NX]
Dorsal hippocampus [NX]
Dorsal spinal cord [NX]
Ductus deferens [NX]
Duodenum [NX]
Dura mater [NX]
Ear cartilage [NX]
Endometrium 1 [NX]
Entorhinal cortex [NX]
Epididymis [NX]
Esophagus [NX]
Facial adipose tissue [NX]
Fallopian tube [NX]
Gallbladder [NX]
Heart atrium [NX]
Heart valve [NX]
Heart wall [NX]
Hypothalamus [NX]
Ileum [NX]
Insular cortex [NX]
Jejunum [NX]
Joint cartilage [NX]
Kidney (cortex) [NX]
Kidney (medulla) [NX]
Larynx [NX]
Lens [NX]
Lip [NX]
Liver [NX]
Lung [NX]
Lymph node [NX]
Medulla [NX]
Midbrain [NX]
Motor cortex [NX]
Nasopharynx epithelium [NX]
Occipital cortex [NX]
Olfactory bulb [NX]
Olfactory epithelium [NX]
Oral mucosa [NX]
Ovary [NX]
Penis [NX]
Periaqueductal gray [NX]
Peritoneum [NX]
Pineal gland [NX]
Pituitary gland [NX]
Pleura [NX]
Pons [NX]
Prefrontal cortex [NX]
Prostate [NX]
Putamen [NX]
Rectum [NX]
Retina [NX]
Retrosplenial cortex [NX]
Salivary gland [NX]
Seminal vesicle [NX]
Septum [NX]
Skeletal muscle [NX]
Skin (back) [NX]
Skin (groin) [NX]
Smooth muscle (intestine) [NX]
Somatosensory cortex [NX]
Spleen [NX]
Stomach (lower) [NX]
Stomach (upper) [NX]
Subcutaneous adipose tissue [NX]
Subiculum [NX]
Substantia nigra [NX]
Superior colliculi [NX]
Synovial tissue [NX]
Temporal cortex [NX]
Testis [NX]
Thalamus [NX]
Thymus [NX]
Thyroid gland [NX]
Tongue [NX]
Tonsil [NX]
Trachea [NX]
Urethral gland [NX]
Urinary bladder [NX]
Vagus nerve [NX]
Ventral hippocampus [NX]
Ventral pallidum [NX]
Ventral spinal cord [NX]
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Gene
i
Gene name, if available.
Ensembl
x
Human ortholog
x
Gene description
x
RNA pig tissue group specificity
x
RNA pig tissue group distribution
x
RNA pig tissue group specific NX
x
PTI
ENSSSCG00000007410
Pancreatic trypsin inhibitor precursor
Tissue enhanced
Detected in some
lung:
20.3
stomach:
22.8
upper respiratory system:
60.4
PTN
ENSSSCG00000016522
ENSG00000105894
Pleiotrophin
Tissue enhanced
Detected in many
brain:
68.8
dura mater:
88.3
gallbladder:
116.6
PTPRH
ENSSSCG00000024567
ENSG00000080031
Protein tyrosine phosphatase, receptor type H
Group enriched
Detected in some
large intestine:
31.1
small intestine:
24.3
stomach:
31.4
PYY
ENSSSCG00000025414
ENSG00000131096
Peptide YY precursor
Tissue enhanced
Detected in some
large intestine:
29.9
small intestine:
88.2
stomach:
21.9
RAB3B
ENSSSCG00000021036
ENSG00000169213
RAB3B, member RAS oncogene family
Group enriched
Detected in many
brain:
27.9
gallbladder:
16.1
pituitary gland:
40.4
stomach:
19.3
RASGRP3
ENSSSCG00000008509
ENSG00000152689
RAS guanyl releasing protein 3
Tissue enhanced
Detected in all
lymphoid tissue:
48.3
REXO2
ENSSSCG00000015056
ENSG00000076043
RNA exonuclease 2
Tissue enhanced
Detected in all
ovary:
85.5
RFX2
ENSSSCG00000035403
ENSG00000087903
Regulatory factor X2
Tissue enhanced
Detected in many
skin:
50.4
testis:
56.2
RFX6
ENSSSCG00000039333
ENSG00000185002
Regulatory factor X6
Tissue enhanced
Detected in some
endometrium:
16.0
esophagus:
11.9
salivary gland:
43.3
RHOBTB3
ENSSSCG00000029805
ENSG00000164292
Rho related BTB domain containing 3
Tissue enriched
Detected in many
lens:
157.9
RNASE1
ENSSSCG00000031649
ENSG00000129538
Ribonuclease pancreatic precursor
Tissue enhanced
Detected in many
brain:
72.9
stomach:
33.9
RTN1
ENSSSCG00000025013
ENSG00000139970
Reticulon-1 isoform 2
Tissue enhanced
Detected in some
brain:
52.6
pineal gland:
20.2
retina:
11.8
RUNX2
ENSSSCG00000001710
ENSG00000124813
Runt related transcription factor 2
Tissue enhanced
Detected in many
ovary:
40.2
stomach:
49.4
RUNX3
ENSSSCG00000032686
ENSG00000020633
Runt related transcription factor 3
Tissue enhanced
Detected in many
lymphoid tissue:
35.4
stomach:
35.2
SCGB1A1
ENSSSCG00000013060
ENSG00000149021
Secretoglobin family 1A member 1
Tissue enriched
Detected in some
lung:
599.3
SCIMP
ENSSSCG00000017896
ENSG00000161929
SLP adaptor and CSK interacting membrane protein
Tissue enhanced
Detected in many
lung:
16.2
lymphoid tissue:
37.2
upper respiratory system:
19.5
SCML4
ENSSSCG00000033392
ENSG00000146285
Scm polycomb group protein like 4
Tissue enhanced
Detected in many
lymphoid tissue:
35.0
small intestine:
25.1
stomach:
20.2
SCNN1B
ENSSSCG00000028923
ENSG00000168447
Sodium channel epithelial 1 beta subunit
Tissue enhanced
Detected in many
kidney:
24.3
stomach:
38.0
SCNN1G
ENSSSCG00000007836
ENSG00000166828
Sodium channel epithelial 1 gamma subunit
Tissue enhanced
Detected in all
kidney:
30.7
stomach:
28.0
SCTR
ENSSSCG00000029536
ENSG00000080293
Secretin receptor precursor
Tissue enhanced
Detected in some
gallbladder:
16.6
kidney:
12.0
small intestine:
14.6
stomach:
18.7
SEMA3C
ENSSSCG00000023784
ENSG00000075223
Semaphorin 3C
Tissue enhanced
Detected in many
cartilage:
97.2
SEMA7A
ENSSSCG00000023165
ENSG00000138623
Semaphorin 7A (John Milton Hagen blood group)
Tissue enhanced
Detected in many
lymphoid tissue:
35.5
ovary:
49.9
SEPT1
ENSSSCG00000007800
ENSG00000180096
Septin-1
Tissue enhanced
Detected in all
lymphoid tissue:
76.7
SFRP2
ENSSSCG00000009004
ENSG00000145423
Secreted frizzled-related protein 2 precursor
Tissue enhanced
Detected in many
dura mater:
179.5
retina:
111.4
SGK1
ENSSSCG00000021443
ENSG00000118515
Serine/threonine-protein kinase Sgk1
Tissue enhanced
Detected in all
choroid plexus:
79.9
SH2D6
ENSSSCG00000008240
ENSG00000152292
SH2 domain containing 6
Tissue enhanced
Detected in many
epididymis:
97.4
vagus nerve:
45.8
SH2D7
ENSSSCG00000001764
ENSG00000183476
SH2 domain containing 7
Tissue enhanced
Detected in many
brain:
27.7
SH3GL2
ENSSSCG00000005177
ENSG00000107295
SH3 domain containing GRB2 like 2, endophilin A1
Tissue enhanced
Detected in many
brain:
55.7
pineal gland:
47.4
retina:
29.4
SHISA3
ENSSSCG00000040147
ENSG00000178343
Shisa family member 3
Tissue enhanced
Detected in many
cartilage:
17.0
vagus nerve:
61.0
SIM2
ENSSSCG00000027179
ENSG00000159263
Single-minded family bHLH transcription factor 2
Tissue enhanced
Detected in some
esophagus:
46.7
male glands:
42.5
stomach:
44.6
SIX2
ENSSSCG00000008446
ENSG00000170577
SIX homeobox 2
Tissue enhanced
Detected in many
dura mater:
40.6
salivary gland:
30.5
upper respiratory system:
27.2
SLC12A2
ENSSSCG00000014255
ENSG00000064651
Solute carrier family 12 member 2
Tissue enriched
Detected in many
male glands:
217.5
SLC12A8
ENSSSCG00000011860
ENSG00000221955
Solute carrier family 12 member 8
Tissue enhanced
Detected in many
esophagus:
16.0
male glands:
38.3
salivary gland:
15.7
SLC15A2
ENSSSCG00000030305
ENSG00000163406
Solute carrier family 15 member 2
Tissue enhanced
Detected in many
lymphoid tissue:
37.7
SLC16A1
ENSSSCG00000006771
ENSG00000155380
Monocarboxylate transporter 1
Tissue enhanced
Detected in many
large intestine:
76.4
SLC23A1
ENSSSCG00000026423
ENSG00000170482
Solute carrier family 23 member 1
Tissue enhanced
Detected in many
kidney:
50.6
male glands:
31.0
SLC27A6
ENSSSCG00000014257
ENSG00000113396
Solute carrier family 27 member 6
Tissue enhanced
Detected in many
choroid plexus:
22.6
kidney:
34.9
SLC2A12
ENSSSCG00000004172
ENSG00000146411
Solute carrier family 2 member 12
Tissue enriched
Detected in many
choroid plexus:
143.9
SLC5A9
ENSSSCG00000003882
ENSG00000117834
Solute carrier family 5 member 9
Group enriched
Detected in some
kidney:
16.0
liver:
23.5
skin:
48.6
small intestine:
25.3
SLC6A9
ENSSSCG00000039770
ENSG00000196517
Solute carrier family 6 member 9
Tissue enhanced
Detected in many
brain:
47.7
retina:
21.4
SLC9A4
ENSSSCG00000008155
ENSG00000180251
Solute carrier family 9 member A4
Group enriched
Detected in some
breast:
12.9
kidney:
17.6
stomach:
48.7
thyroid gland:
13.6
SLC9B2
ENSSSCG00000028101
ENSG00000164038
Solute carrier family 9 member B2
Tissue enhanced
Detected in many
dura mater:
29.9
heart:
30.6
SNX10
ENSSSCG00000037598
ENSG00000086300
Sorting nexin 10
Tissue enhanced
Detected in many
brain:
32.5
epididymis:
20.9
pineal gland:
25.2
SOCS1
ENSSSCG00000027855
ENSG00000185338
Suppressor of cytokine signaling 1
Tissue enhanced
Detected in many
cartilage:
76.2
stomach:
35.0
SOCS3
ENSSSCG00000036956
ENSG00000184557
Suppressor of cytokine signaling 3
Tissue enhanced
Detected in many
aorta:
47.5
mesothelial tissue:
62.6
ovary:
66.1
SPARCL1
ENSSSCG00000009222
ENSG00000152583
SPARC-like protein 1 precursor
Tissue enhanced
Detected in all
cervix:
136.6
smooth muscle:
134.5
SPATS2L
ENSSSCG00000016090
ENSG00000196141
SPATS2-like protein
Tissue enhanced
Detected in all
thyroid gland:
99.1
SPSB4
ENSSSCG00000034369
ENSG00000175093
SplA/ryanodine receptor domain and SOCS box containing 4
Tissue enhanced
Detected in many
heart:
19.7
large intestine:
18.1
SST
ENSSSCG00000033815
ENSG00000157005
Somatostatin Somatostatin-28 Somatostatin-14
Tissue enhanced
Detected in many
brain:
31.9
small intestine:
13.8
stomach:
17.6
ST18
ENSSSCG00000006266
ENSG00000147488
ST18, C2H2C-type zinc finger
Tissue enriched
Detected in some
brain:
41.0
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