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Human disease related genes
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UMAP gene cluster
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Biological process
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Disease
Keyword
Chromosome
1
2
3
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5
6
7
8
9
10
11
12
13
14
15
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MT
Unmapped
X
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External id
Variability
Variable
Not variable
Tissue
Any
Adipose tissue
Brain
Cartilage
Heart
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Large intestine
Lymphoid tissue
Male glands
Mesothelial tissue
Mouth
Skin
Small intestine
Stomach 1
Upper respiratory system
Cluster
1 - Brain neurotransmission
2 - Brain neurotransmission
3 - Brain cellular structure
4 - Brain development
5 - Intracellular signalling
6 - Brain uncharacterized
7 - Retinal
8 - Neurohormonal
9 - Testis spermatogenesis
10 - Housekeeping transcription
11 - Testis uncharacterized
12 - Metabolic
13 - Testis sperm
14 - Low abundant uncharacterized
15 - Testis uncharacterized
16 - Aorta uncharacterized
17 - Cilium structure
18 - Low abundant uncharacterized
19 - Housekeeping mitochondrial
20 - Hormonal
21 - Low abundant uncharacterized
22 - Housekeeping transcription
23 - Cilium structure
24 - Low abundant uncharacterized
25 - Low abundant uncharacterized
26 - Low abundant uncharacterized
27 - Low abundant uncharacterized
28 - Housekeeping mitochondrial translation
29 - Male tissue bacterial defense
30 - Housekeeping structural
31 - Housekeeping uncharacterized
32 - Transport
33 - Lens
34 - Prostate uncharacterized
35 - Low abundant uncharacterized
36 - Receptors uncharacterized
37 - Olfactory bulb
38 - Lung and thyroid development
39 - Kidney transport
40 - Testis
41 - Low abundant uncharacterized
42 - Low abundant uncharacterized
43 - Breast uncharacterized
44 - Housekeeping
45 - Thymus uncharacterized
46 - Skeletal muscle contraction
47 - Spleen uncharacterized
48 - Low abundant uncharacterized
49 - Heart contraction
50 - Muscle contraction
51 - Liver and kidney
52 - Housekeeping
53 - Housekeeping mitochondrial
54 - Interferons
55 - Low abundant uncharacterized
56 - Low abundant uncharacterized
57 - Skin
58 - Immune cells
59 - Squamous epithelium
60 - Not detected
61 - Enzymes and secretion
62 - Squamous epithelium
63 - Small intestine
64 - Gastrointestinal
65 - Epithelium
66 - Housekeeping mRNA
67 - Gastrointestinal
68 - Housekeeping protein processing
69 - Housekeeping
70 - Housekeeping
71 - Housekeeping regulation
72 - Digestive and respiratory defense
73 - Housekeeping cell cycle
74 - Extracellular matrix
75 - Housekeeping
76 - Housekeeping regulation
77 - Housekeeping defense
78 - Lymphoid T cells
79 - Lymphoid myeloid
80 - Heart uncharacterized
81 - Vasculature and connective tissue
82 - Lymphoid B cell
83 - Not detected
84 - Epithelium transcription regulation
Tissue group
Any
Adipose tissue
Adrenal gland
Aorta
Bone marrow
Brain
Breast
Cartilage
Cervix
Choroid plexus
Cornea
Ductus deferens
Dura mater
Endometrium
Epididymis
Esophagus
Fallopian tube
Gallbladder
Heart
Kidney
Large intestine
Lens
Liver
Lung
Lymphoid tissue
Male glands
Mesothelial tissue
Mouth
Ovary
Penis
Pineal gland
Pituitary gland
Retina
Salivary gland
Skeletal muscle
Skin
Small intestine
Smooth muscle
Stomach
Synovial tissue
Testis
Thyroid gland
Upper respiratory system
Urinary bladder
Vagus nerve
Category
Tissue enriched
Group enriched
Tissue enhanced
Low tissue specificity
Not detected
Detected in all
Detected in many
Detected in some
Detected in single
Is highest expressed
Brain region
Any
Amygdala
Basal ganglia
Cerebellum
Cerebral cortex
Corpus callosum
Hippocampal formation
Hypothalamus
Midbrain
Olfactory region
Pituitary gland
Pons and medulla
Retina
Spinal cord
Thalamus
Category
Region enriched
Group enriched
Region enhanced
Low region specificity
Not detected
Detected in all
Detected in many
Detected in some
Detected in single
Is highest expressed
Column
Gene
Position
Tissue specific score
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THE PIG PROTEOME
THE PIG ATLAS
TISSUE SPECIFIC PROTEOME
UMAP GENE CLUSTERING
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3366 GENES FOUND
Gene
Gene
i
Gene name, if available.
Gene synonym (Human ortholog)
Ensembl gene id
Ensembl gene id (Proteincoding human ortholog)
Gene description
Uniprot accession (Human ortholog)
Chromosome
Chromosome position
Related human disease
RNA category pig
RNA pig tissue group specificity
RNA pig tissue group distribution
RNA pig tissue group specificity score
RNA pig tissue group specific NX
RNA pig brain regional specificity
RNA pig brain regional distribution
RNA pig brain regional specificity score
RNA pig brain regional specific pTPM
Annotation
UMAP cluster
Within tissue variation
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1.
Select data columns:
Gene
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Gene
i
Gene name, if available.
Gene synonym (Human ortholog)
Ensembl gene id
Ensembl gene id (Proteincoding human ortholog)
Gene description
Uniprot accession (Human ortholog)
Chromosome
Chromosome position
Related human disease
RNA category pig
Expand
RNA pig tissue group specificity
RNA pig tissue group distribution
RNA pig tissue group specificity score
RNA pig tissue group specific NX
RNA pig brain regional specificity
RNA pig brain regional distribution
RNA pig brain regional specificity score
RNA pig brain regional specific pTPM
Annotation
Expand
UMAP cluster
Within tissue variation
Pig Tissue RNA
Expand
Abdominal adipose tissue [NX]
Adrenal gland [NX]
Amygdala [NX]
Aorta [NX]
Bone marrow [NX]
Breast [NX]
Bronchus [NX]
Bulbourethral gland [NX]
Caudate [NX]
Cecum [NX]
Cerebellum [NX]
Cervix [NX]
Choroid plexus [NX]
Cingulate cortex [NX]
Colon [NX]
Cornea [NX]
Corpus callosum [NX]
Dorsal hippocampus [NX]
Dorsal spinal cord [NX]
Ductus deferens [NX]
Duodenum [NX]
Dura mater [NX]
Ear cartilage [NX]
Endometrium 1 [NX]
Entorhinal cortex [NX]
Epididymis [NX]
Esophagus [NX]
Facial adipose tissue [NX]
Fallopian tube [NX]
Gallbladder [NX]
Heart atrium [NX]
Heart valve [NX]
Heart wall [NX]
Hypothalamus [NX]
Ileum [NX]
Insular cortex [NX]
Jejunum [NX]
Joint cartilage [NX]
Kidney (cortex) [NX]
Kidney (medulla) [NX]
Larynx [NX]
Lens [NX]
Lip [NX]
Liver [NX]
Lung [NX]
Lymph node [NX]
Medulla [NX]
Midbrain [NX]
Motor cortex [NX]
Nasopharynx epithelium [NX]
Occipital cortex [NX]
Olfactory bulb [NX]
Olfactory epithelium [NX]
Oral mucosa [NX]
Ovary [NX]
Penis [NX]
Periaqueductal gray [NX]
Peritoneum [NX]
Pineal gland [NX]
Pituitary gland [NX]
Pleura [NX]
Pons [NX]
Prefrontal cortex [NX]
Prostate [NX]
Putamen [NX]
Rectum [NX]
Retina [NX]
Retrosplenial cortex [NX]
Salivary gland [NX]
Seminal vesicle [NX]
Septum [NX]
Skeletal muscle [NX]
Skin (back) [NX]
Skin (groin) [NX]
Smooth muscle (intestine) [NX]
Somatosensory cortex [NX]
Spleen [NX]
Stomach (lower) [NX]
Stomach (upper) [NX]
Subcutaneous adipose tissue [NX]
Subiculum [NX]
Substantia nigra [NX]
Superior colliculi [NX]
Synovial tissue [NX]
Temporal cortex [NX]
Testis [NX]
Thalamus [NX]
Thymus [NX]
Thyroid gland [NX]
Tongue [NX]
Tonsil [NX]
Trachea [NX]
Urethral gland [NX]
Urinary bladder [NX]
Vagus nerve [NX]
Ventral hippocampus [NX]
Ventral pallidum [NX]
Ventral spinal cord [NX]
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Gene
i
Gene name, if available.
Ensembl
x
Human ortholog
x
Gene description
x
RNA pig tissue group specificity
x
RNA pig tissue group distribution
x
RNA pig tissue group specific NX
x
NDUFB9
ENSSSCG00000005976
ENSG00000147684
NADH:ubiquinone oxidoreductase subunit B9
Tissue enhanced
Detected in all
skeletal muscle:
173.3
NDUFS5
ENSSSCG00000003653
ENSG00000168653
NADH dehydrogenase
Low tissue specificity
Detected in all
NDUFV2
ENSSSCG00000038826
ENSG00000178127
Tissue enhanced
Detected in all
lens:
129.7
NEBL
ENSSSCG00000011090
ENSG00000078114
Nebulette
Tissue enriched
Detected in many
heart:
215.3
NECAB3
ENSSSCG00000029626
ENSG00000125967
N-terminal EF-hand calcium binding protein 3
Tissue enhanced
Detected in many
brain:
24.0
NECTIN1
ENSSSCG00000015125
ENSG00000110400
Nectin-1 precursor
Tissue enhanced
Detected in many
skin:
34.6
urinary bladder:
38.1
NECTIN3
ENSSSCG00000011933
ENSG00000177707
Nectin cell adhesion molecule 3
Group enriched
Detected in all
lens:
124.3
liver:
50.2
male glands:
31.6
testis:
60.3
NEDD4L
ENSSSCG00000004919
ENSG00000049759
Neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
Low tissue specificity
Detected in all
NEDD8
ENSSSCG00000031938
ENSG00000129559
Neural precursor cell expressed, developmentally down-regulated 8
Low tissue specificity
Detected in all
NEK3
ENSSSCG00000009379
ENSG00000136098
NIMA related kinase 3
Low tissue specificity
Detected in all
NEK6
ENSSSCG00000005587
ENSG00000119408
Serine/threonine-protein kinase Nek6
Low tissue specificity
Detected in all
NFXL1
ENSSSCG00000008816
ENSG00000170448
Nuclear transcription factor, X-box binding like 1
Tissue enhanced
Detected in all
male glands:
43.5
NGF
ENSSSCG00000032417
ENSG00000134259
Nerve growth factor
Low tissue specificity
Detected in all
NIFK
ENSSSCG00000015730
ENSG00000155438
MKI67 FHA domain-interacting nucleolar phosphoprotein
Low tissue specificity
Detected in all
NIM1K
ENSSSCG00000016873
ENSG00000177453
NIM1 serine/threonine protein kinase
Low tissue specificity
Detected in many
NIPA2
ENSSSCG00000036898
ENSG00000140157
Non imprinted in Prader-Willi/Angelman syndrome 2
Low tissue specificity
Detected in all
NIPAL1
ENSSSCG00000037950
ENSG00000163293
NIPA like domain containing 1
Tissue enhanced
Detected in many
male glands:
42.3
NIPAL3
ENSSSCG00000003543
ENSG00000001461
NIPA like domain containing 3
Low tissue specificity
Detected in all
NIT2
ENSSSCG00000011968
ENSG00000114021
Omega-amidase NIT2
Tissue enhanced
Detected in all
male glands:
81.4
NKAIN3
ENSSSCG00000034894
ENSG00000185942
Sodium/potassium transporting ATPase interacting 3
Tissue enhanced
Detected in all
brain:
28.0
NKD1
ENSSSCG00000039875
ENSG00000140807
Naked cuticle homolog 1
Low tissue specificity
Detected in many
NKPD1
ENSSSCG00000035833
ENSG00000179846
NTPase KAP family P-loop domain containing 1
Tissue enhanced
Detected in many
salivary gland:
11.3
skin:
19.8
NKX3-1
ENSSSCG00000031924
ENSG00000167034
NK3 homeobox 1
Tissue enriched
Detected in some
male glands:
206.7
NLN
ENSSSCG00000016778
ENSG00000123213
Neurolysin, mitochondrial
Tissue enhanced
Detected in all
liver:
36.2
NLRC5
ENSSSCG00000039751
ENSG00000140853
Protein NLRC5
Tissue enhanced
Detected in many
lymphoid tissue:
34.2
stomach:
48.2
NMD3
ENSSSCG00000022952
ENSG00000169251
NMD3 ribosome export adaptor
Low tissue specificity
Detected in all
NME2
ENSSSCG00000017591
ENSG00000011052,ENSG00000243678
Nucleoside diphosphate kinase B
Tissue enhanced
Detected in all
male glands:
143.6
NNT
ENSSSCG00000016877
ENSG00000112992
Nicotinamide nucleotide transhydrogenase
Tissue enhanced
Detected in all
skeletal muscle:
81.1
NOL4L
ENSSSCG00000007249
ENSG00000197183
Nucleolar protein 4 like
Low tissue specificity
Detected in all
NOP2
ENSSSCG00000000696
ENSG00000111641
Probable 28S rRNA (cytosine(4447)-C(5))-methyltransferase
Tissue enhanced
Detected in all
epididymis:
67.1
NOS2
ENSSSCG00000017755
ENSG00000007171
Nitric oxide synthase, inducible
Tissue enhanced
Detected in many
cartilage:
34.7
large intestine:
42.1
NOS3
ENSSSCG00000016450
ENSG00000164867
Nitric oxide synthase, endothelial
Tissue enhanced
Detected in many
penis:
48.6
NOSTRIN
ENSSSCG00000015923
ENSG00000163072
Nitric oxide synthase trafficking
Low tissue specificity
Detected in many
NOTCH1
ENSSSCG00000038509
ENSG00000148400
Notch 1
Low tissue specificity
Detected in all
NOTCH2
ENSSSCG00000006709
ENSG00000134250
Notch 2
Low tissue specificity
Detected in all
NOTCH4
ENSSSCG00000001440
ENSG00000204301
Neurogenic locus notch homolog protein 4 precursor
Low tissue specificity
Detected in many
NOVA1
ENSSSCG00000024396
ENSG00000139910
NOVA alternative splicing regulator 1
Tissue enhanced
Detected in many
brain:
35.0
synovial tissue:
21.8
NPAS3
ENSSSCG00000001964
ENSG00000151322
Neuronal PAS domain protein 3
Tissue enhanced
Detected in many
brain:
18.5
cartilage:
25.9
NPBWR1
ENSSSCG00000021483
ENSG00000183729
Neuropeptides B and W receptor 1
Tissue enhanced
Detected in some
brain:
9.4
epididymis:
14.4
ovary:
31.8
salivary gland:
7.4
NPC2
ENSSSCG00000002366
ENSG00000119655
Epididymal secretory protein E1
Tissue enriched
Detected in many
epididymis:
615.2
NPM1
ENSSSCG00000016998
ENSG00000181163
Nucleophosmin 1
Low tissue specificity
Detected in all
NPM3
ENSSSCG00000010568
ENSG00000107833
Nucleophosmin/nucleoplasmin 3
Low tissue specificity
Detected in all
NPPC
ENSSSCG00000026852
ENSG00000163273
C-type natriuretic peptide CNP-22 CNP-29 CNP-53
Tissue enriched
Detected in some
male glands:
300.0
NPR3
ENSSSCG00000036201
ENSG00000113389
Natriuretic peptide receptor 3
Tissue enhanced
Detected in many
choroid plexus:
21.9
cornea:
33.2
lens:
39.8
NPY2R
ENSSSCG00000008993
ENSG00000185149
Neuropeptide Y receptor type 2
Tissue enhanced
Detected in many
brain:
15.1
cervix:
37.5
NR0B1
ENSSSCG00000012199
ENSG00000169297
Nuclear receptor subfamily 0 group B member 1
Group enriched
Detected in some
adrenal gland:
13.9
male glands:
12.3
pituitary gland:
4.0
testis:
3.6
NR1D1
ENSSSCG00000036933
ENSG00000126368
Nuclear receptor subfamily 1 group D member 1
Low tissue specificity
Detected in all
NR2F1
ENSSSCG00000014157
ENSG00000175745
Nuclear receptor subfamily 2 group F member 1
Low tissue specificity
Detected in many
NR4A1
ENSSSCG00000031321
ENSG00000123358
Nuclear receptor subfamily 4 group A member 1
Tissue enhanced
Detected in many
cartilage:
138.9
NR4A2
ENSSSCG00000015871
ENSG00000153234
Nuclear receptor subfamily 4 group A member 2
Tissue enhanced
Detected in many
cartilage:
110.4
male glands:
119.9
vagus nerve:
70.0
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