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Human disease related genes
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UMAP gene cluster
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Keyword
Chromosome
1
2
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6
7
8
9
10
11
12
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MT
Unmapped
X
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External id
Variability
Variable
Not variable
Tissue
Any
Adipose tissue
Brain
Cartilage
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Lymphoid tissue
Male glands
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Mouth
Skin
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Stomach 1
Upper respiratory system
Cluster
1 - Brain neurotransmission
2 - Brain neurotransmission
3 - Brain cellular structure
4 - Brain development
5 - Intracellular signalling
6 - Brain uncharacterized
7 - Retinal
8 - Neurohormonal
9 - Testis spermatogenesis
10 - Housekeeping transcription
11 - Testis uncharacterized
12 - Metabolic
13 - Testis sperm
14 - Low abundant uncharacterized
15 - Testis uncharacterized
16 - Aorta uncharacterized
17 - Cilium structure
18 - Low abundant uncharacterized
19 - Housekeeping mitochondrial
20 - Hormonal
21 - Low abundant uncharacterized
22 - Housekeeping transcription
23 - Cilium structure
24 - Low abundant uncharacterized
25 - Low abundant uncharacterized
26 - Low abundant uncharacterized
27 - Low abundant uncharacterized
28 - Housekeeping mitochondrial translation
29 - Male tissue bacterial defense
30 - Housekeeping structural
31 - Housekeeping uncharacterized
32 - Transport
33 - Lens
34 - Prostate uncharacterized
35 - Low abundant uncharacterized
36 - Receptors uncharacterized
37 - Olfactory bulb
38 - Lung and thyroid development
39 - Kidney transport
40 - Testis
41 - Low abundant uncharacterized
42 - Low abundant uncharacterized
43 - Breast uncharacterized
44 - Housekeeping
45 - Thymus uncharacterized
46 - Skeletal muscle contraction
47 - Spleen uncharacterized
48 - Low abundant uncharacterized
49 - Heart contraction
50 - Muscle contraction
51 - Liver and kidney
52 - Housekeeping
53 - Housekeeping mitochondrial
54 - Interferons
55 - Low abundant uncharacterized
56 - Low abundant uncharacterized
57 - Skin
58 - Immune cells
59 - Squamous epithelium
60 - Not detected
61 - Enzymes and secretion
62 - Squamous epithelium
63 - Small intestine
64 - Gastrointestinal
65 - Epithelium
66 - Housekeeping mRNA
67 - Gastrointestinal
68 - Housekeeping protein processing
69 - Housekeeping
70 - Housekeeping
71 - Housekeeping regulation
72 - Digestive and respiratory defense
73 - Housekeeping cell cycle
74 - Extracellular matrix
75 - Housekeeping
76 - Housekeeping regulation
77 - Housekeeping defense
78 - Lymphoid T cells
79 - Lymphoid myeloid
80 - Heart uncharacterized
81 - Vasculature and connective tissue
82 - Lymphoid B cell
83 - Not detected
84 - Epithelium transcription regulation
Tissue group
Any
Adipose tissue
Adrenal gland
Aorta
Bone marrow
Brain
Breast
Cartilage
Cervix
Choroid plexus
Cornea
Ductus deferens
Dura mater
Endometrium
Epididymis
Esophagus
Fallopian tube
Gallbladder
Heart
Kidney
Large intestine
Lens
Liver
Lung
Lymphoid tissue
Male glands
Mesothelial tissue
Mouth
Ovary
Penis
Pineal gland
Pituitary gland
Retina
Salivary gland
Skeletal muscle
Skin
Small intestine
Smooth muscle
Stomach
Synovial tissue
Testis
Thyroid gland
Upper respiratory system
Urinary bladder
Vagus nerve
Category
Tissue enriched
Group enriched
Tissue enhanced
Low tissue specificity
Not detected
Detected in all
Detected in many
Detected in some
Detected in single
Is highest expressed
Brain region
Any
Amygdala
Basal ganglia
Cerebellum
Cerebral cortex
Corpus callosum
Hippocampal formation
Hypothalamus
Midbrain
Olfactory region
Pituitary gland
Pons and medulla
Retina
Spinal cord
Thalamus
Category
Region enriched
Group enriched
Region enhanced
Low region specificity
Not detected
Detected in all
Detected in many
Detected in some
Detected in single
Is highest expressed
Column
Gene
Position
Tissue specific score
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THE PIG PROTEOME
THE PIG ATLAS
TISSUE SPECIFIC PROTEOME
UMAP GENE CLUSTERING
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1362 GENES FOUND
Gene
Gene
i
Gene name, if available.
Gene synonym (Human ortholog)
Ensembl gene id
Ensembl gene id (Proteincoding human ortholog)
Gene description
Uniprot accession (Human ortholog)
Chromosome
Chromosome position
Related human disease
RNA category pig
RNA pig tissue group specificity
RNA pig tissue group distribution
RNA pig tissue group specificity score
RNA pig tissue group specific NX
RNA pig brain regional specificity
RNA pig brain regional distribution
RNA pig brain regional specificity score
RNA pig brain regional specific pTPM
Annotation
UMAP cluster
Within tissue variation
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1.
Select data columns:
Gene
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Gene
i
Gene name, if available.
Gene synonym (Human ortholog)
Ensembl gene id
Ensembl gene id (Proteincoding human ortholog)
Gene description
Uniprot accession (Human ortholog)
Chromosome
Chromosome position
Related human disease
RNA category pig
Expand
RNA pig tissue group specificity
RNA pig tissue group distribution
RNA pig tissue group specificity score
RNA pig tissue group specific NX
RNA pig brain regional specificity
RNA pig brain regional distribution
RNA pig brain regional specificity score
RNA pig brain regional specific pTPM
Annotation
Expand
UMAP cluster
Within tissue variation
Pig Tissue RNA
Expand
Abdominal adipose tissue [NX]
Adrenal gland [NX]
Amygdala [NX]
Aorta [NX]
Bone marrow [NX]
Breast [NX]
Bronchus [NX]
Bulbourethral gland [NX]
Caudate [NX]
Cecum [NX]
Cerebellum [NX]
Cervix [NX]
Choroid plexus [NX]
Cingulate cortex [NX]
Colon [NX]
Cornea [NX]
Corpus callosum [NX]
Dorsal hippocampus [NX]
Dorsal spinal cord [NX]
Ductus deferens [NX]
Duodenum [NX]
Dura mater [NX]
Ear cartilage [NX]
Endometrium 1 [NX]
Entorhinal cortex [NX]
Epididymis [NX]
Esophagus [NX]
Facial adipose tissue [NX]
Fallopian tube [NX]
Gallbladder [NX]
Heart atrium [NX]
Heart valve [NX]
Heart wall [NX]
Hypothalamus [NX]
Ileum [NX]
Insular cortex [NX]
Jejunum [NX]
Joint cartilage [NX]
Kidney (cortex) [NX]
Kidney (medulla) [NX]
Larynx [NX]
Lens [NX]
Lip [NX]
Liver [NX]
Lung [NX]
Lymph node [NX]
Medulla [NX]
Midbrain [NX]
Motor cortex [NX]
Nasopharynx epithelium [NX]
Occipital cortex [NX]
Olfactory bulb [NX]
Olfactory epithelium [NX]
Oral mucosa [NX]
Ovary [NX]
Penis [NX]
Periaqueductal gray [NX]
Peritoneum [NX]
Pineal gland [NX]
Pituitary gland [NX]
Pleura [NX]
Pons [NX]
Prefrontal cortex [NX]
Prostate [NX]
Putamen [NX]
Rectum [NX]
Retina [NX]
Retrosplenial cortex [NX]
Salivary gland [NX]
Seminal vesicle [NX]
Septum [NX]
Skeletal muscle [NX]
Skin (back) [NX]
Skin (groin) [NX]
Smooth muscle (intestine) [NX]
Somatosensory cortex [NX]
Spleen [NX]
Stomach (lower) [NX]
Stomach (upper) [NX]
Subcutaneous adipose tissue [NX]
Subiculum [NX]
Substantia nigra [NX]
Superior colliculi [NX]
Synovial tissue [NX]
Temporal cortex [NX]
Testis [NX]
Thalamus [NX]
Thymus [NX]
Thyroid gland [NX]
Tongue [NX]
Tonsil [NX]
Trachea [NX]
Urethral gland [NX]
Urinary bladder [NX]
Vagus nerve [NX]
Ventral hippocampus [NX]
Ventral pallidum [NX]
Ventral spinal cord [NX]
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Gene
i
Gene name, if available.
Ensembl
x
Human ortholog
x
Gene description
x
RNA pig tissue group specificity
x
RNA pig tissue group distribution
x
RNA pig tissue group specific NX
x
GUCY1B1
ENSSSCG00000008870
ENSG00000061918
Guanylate cyclase soluble subunit beta-1
Tissue enhanced
Detected in many
pineal gland:
40.0
HDAC4
ENSSSCG00000024777
ENSG00000068024
Histone deacetylase 4
Low tissue specificity
Detected in all
HDAC9
ENSSSCG00000015368
ENSG00000048052
Histone deacetylase 9
Tissue enhanced
Detected in all
cartilage:
53.6
HECTD2
ENSSSCG00000020912
ENSG00000165338
HECT domain E3 ubiquitin protein ligase 2
Tissue enhanced
Detected in many
brain:
43.7
male glands:
22.5
HECW2
ENSSSCG00000016068
ENSG00000138411
E3 ubiquitin-protein ligase HECW2
Low tissue specificity
Detected in many
HERC5
ENSSSCG00000030548
ENSG00000138646
HECT and RLD domain containing E3 ubiquitin protein ligase 5
Low tissue specificity
Detected in many
HERC6
ENSSSCG00000021712
ENSG00000138642
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
Low tissue specificity
Detected in many
HES2
ENSSSCG00000034297
ENSG00000069812
Hes family bHLH transcription factor 2
Tissue enhanced
Detected in many
epididymis:
27.7
HES4
ENSSSCG00000035420
ENSG00000188290
Hes family bHLH transcription factor 4
Low tissue specificity
Detected in all
HHIP
ENSSSCG00000009045
ENSG00000164161
Hedgehog interacting protein
Tissue enhanced
Detected in many
cartilage:
79.0
lymphoid tissue:
59.2
HHIPL1
ENSSSCG00000022794
ENSG00000182218
HHIP like 1
Tissue enhanced
Detected in many
cartilage:
64.4
HIF1A
ENSSSCG00000005096
ENSG00000100644
Hypoxia-inducible factor 1-alpha
Tissue enhanced
Detected in all
cartilage:
106.3
HIVEP1
ENSSSCG00000001049
ENSG00000095951
Human immunodeficiency virus type I enhancer binding protein 1
Low tissue specificity
Detected in all
HIVEP2
ENSSSCG00000004138
ENSG00000010818
Human immunodeficiency virus type I enhancer binding protein 2
Tissue enhanced
Detected in all
cartilage:
67.2
HK2
ENSSSCG00000008261
ENSG00000159399
Hexokinase-2
Low tissue specificity
Detected in many
HLA-DRA
ENSSSCG00000001453
ENSG00000204287
MHC class II DR-alpha precursor
Tissue enhanced
Detected in many
lymphoid tissue:
150.4
HOXA10
ENSSSCG00000021204
ENSG00000253293
Homeobox protein Hox-A10
Tissue enhanced
Detected in many
cartilage:
42.7
ductus deferens:
37.9
kidney:
38.5
male glands:
45.3
urinary bladder:
40.7
HOXA11
ENSSSCG00000016698
ENSG00000005073
Homeobox A11
Tissue enhanced
Detected in some
cartilage:
17.3
cervix:
21.1
ductus deferens:
18.5
endometrium:
28.1
male glands:
27.2
HOXA13
ENSSSCG00000029666
ENSG00000106031
Homeobox protein Hox-A13
Tissue enhanced
Detected in some
cervix:
54.1
male glands:
25.8
urinary bladder:
31.9
HOXA2
ENSSSCG00000016706
ENSG00000105996
Homeobox A2
Tissue enhanced
Detected in many
male glands:
21.9
HOXA3
ENSSSCG00000016705
ENSG00000105997
Homeobox A3
Low tissue specificity
Detected in many
HOXA4
ENSSSCG00000016704
ENSG00000197576
Homeobox A4
Tissue enhanced
Detected in many
male glands:
28.6
HOXA5
ENSSSCG00000016703
ENSG00000106004
Homeobox protein Hox-A5
Tissue enhanced
Detected in many
epididymis:
34.4
male glands:
42.7
HOXA7
ENSSSCG00000016701
ENSG00000122592
Homeobox A7
Low tissue specificity
Detected in many
HOXB3
ENSSSCG00000017534
ENSG00000120093
Homeobox B3
Tissue enhanced
Detected in many
male glands:
64.2
HOXD8
ENSSSCG00000040349
ENSG00000175879
Homeobox D8
Tissue enhanced
Detected in many
adrenal gland:
26.3
cartilage:
24.8
epididymis:
42.1
HRH1
ENSSSCG00000011576
ENSG00000196639
Histamine receptor H1
Low tissue specificity
Detected in all
HS3ST1
ENSSSCG00000021515
ENSG00000002587
Heparan sulfate-glucosamine 3-sulfotransferase 1
Tissue enhanced
Detected in many
cartilage:
54.1
epididymis:
32.4
HSPA12A
ENSSSCG00000036758
ENSG00000165868
Heat shock protein family A (Hsp70) member 12A
Tissue enhanced
Detected in many
brain:
48.2
vagus nerve:
36.5
HSPA13
ENSSSCG00000012007
ENSG00000155304
Heat shock protein family A (Hsp70) member 13
Tissue enhanced
Detected in all
pineal gland:
31.8
pituitary gland:
58.8
HSPA2
ENSSSCG00000002274
ENSG00000126803
Heat shock protein family A (Hsp70) member 2
Tissue enhanced
Detected in many
brain:
72.2
cornea:
50.0
testis:
72.1
vagus nerve:
68.5
HSPA5
ENSSSCG00000005601
ENSG00000044574
Heat shock protein family A (Hsp70) member 5
Low tissue specificity
Detected in all
HSPB8
ENSSSCG00000009844
ENSG00000152137
Heat shock protein family B (small) member 8
Tissue enhanced
Detected in many
skeletal muscle:
123.2
HTRA3
ENSSSCG00000008723
ENSG00000170801
Serine protease HTRA3 precursor
Tissue enhanced
Detected in many
lens:
46.6
mesothelial tissue:
88.8
IBSP
ENSSSCG00000009219
ENSG00000029559
Integrin binding sialoprotein
Group enriched
Detected in some
bone marrow:
43.8
cartilage:
19.9
dura mater:
44.2
ovary:
57.5
ICAM1
ENSSSCG00000013655
ENSG00000090339
Intercellular adhesion molecule 1 precursor
Tissue enhanced
Detected in many
lung:
45.5
ICAM2
ENSSSCG00000039909
ENSG00000108622
Intercellular adhesion molecule 2 precursor
Low tissue specificity
Detected in many
ID2
ENSSSCG00000008645
ENSG00000115738
DNA-binding protein inhibitor ID-2
Tissue enhanced
Detected in many
cartilage:
124.2
IER3
ENSSSCG00000027607
ENSG00000137331
Immediate early response 3
Tissue enhanced
Detected in many
cartilage:
140.2
IFI44
ENSSSCG00000003763
ENSG00000137965
Interferon-induced protein 44
Low tissue specificity
Detected in many
IFI6
ENSSSCG00000034570
ENSG00000126709
Interferon alpha inducible protein 6
Tissue enhanced
Detected in many
liver:
106.7
IGFBP2
ENSSSCG00000035392
ENSG00000115457
Insulin-like growth factor-binding protein 2
Tissue enhanced
Detected in many
choroid plexus:
61.1
cornea:
73.1
liver:
114.0
IGFBP3
ENSSSCG00000038783
ENSG00000146674
Insulin-like growth factor-binding protein 3
Tissue enhanced
Detected in many
upper respiratory system:
84.2
urinary bladder:
77.7
IGFBP4
ENSSSCG00000017472
ENSG00000141753
Insulin-like growth factor-binding protein 4 precursor
Tissue enhanced
Detected in many
ovary:
147.0
IGFBP7
ENSSSCG00000008913
ENSG00000163453
Insulin-like growth factor-binding protein 7 precursor
Low tissue specificity
Detected in all
IGSF11
ENSSSCG00000011906
ENSG00000144847
Immunoglobulin superfamily member 11
Tissue enhanced
Detected in many
brain:
36.0
retina:
13.2
vagus nerve:
14.8
IL10RA
ENSSSCG00000015085
ENSG00000110324
Interleukin 10 receptor subunit alpha
Tissue enhanced
Detected in many
lymphoid tissue:
47.1
IL11
ENSSSCG00000040725
ENSG00000095752
Interleukin 11
Tissue enriched
Detected in some
ovary:
130.1
IL17RD
ENSSSCG00000011463
ENSG00000144730
Interleukin 17 receptor D
Tissue enhanced
Detected in many
pituitary gland:
26.0
IL18
ENSSSCG00000015037
ENSG00000150782
Interleukin-18
Low tissue specificity
Detected in many
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