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Human disease related genes
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UMAP gene cluster
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Keyword
Chromosome
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
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18
MT
Unmapped
X
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External id
Variability
Variable
Not variable
Tissue
Any
Adipose tissue
Brain
Cartilage
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Lymphoid tissue
Male glands
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Mouth
Skin
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Stomach 1
Upper respiratory system
Cluster
1 - Brain neurotransmission
2 - Brain neurotransmission
3 - Brain cellular structure
4 - Brain development
5 - Intracellular signalling
6 - Brain uncharacterized
7 - Retinal
8 - Neurohormonal
9 - Testis spermatogenesis
10 - Housekeeping transcription
11 - Testis uncharacterized
12 - Metabolic
13 - Testis sperm
14 - Low abundant uncharacterized
15 - Testis uncharacterized
16 - Aorta uncharacterized
17 - Cilium structure
18 - Low abundant uncharacterized
19 - Housekeeping mitochondrial
20 - Hormonal
21 - Low abundant uncharacterized
22 - Housekeeping transcription
23 - Cilium structure
24 - Low abundant uncharacterized
25 - Low abundant uncharacterized
26 - Low abundant uncharacterized
27 - Low abundant uncharacterized
28 - Housekeeping mitochondrial translation
29 - Male tissue bacterial defense
30 - Housekeeping structural
31 - Housekeeping uncharacterized
32 - Transport
33 - Lens
34 - Prostate uncharacterized
35 - Low abundant uncharacterized
36 - Receptors uncharacterized
37 - Olfactory bulb
38 - Lung and thyroid development
39 - Kidney transport
40 - Testis
41 - Low abundant uncharacterized
42 - Low abundant uncharacterized
43 - Breast uncharacterized
44 - Housekeeping
45 - Thymus uncharacterized
46 - Skeletal muscle contraction
47 - Spleen uncharacterized
48 - Low abundant uncharacterized
49 - Heart contraction
50 - Muscle contraction
51 - Liver and kidney
52 - Housekeeping
53 - Housekeeping mitochondrial
54 - Interferons
55 - Low abundant uncharacterized
56 - Low abundant uncharacterized
57 - Skin
58 - Immune cells
59 - Squamous epithelium
60 - Not detected
61 - Enzymes and secretion
62 - Squamous epithelium
63 - Small intestine
64 - Gastrointestinal
65 - Epithelium
66 - Housekeeping mRNA
67 - Gastrointestinal
68 - Housekeeping protein processing
69 - Housekeeping
70 - Housekeeping
71 - Housekeeping regulation
72 - Digestive and respiratory defense
73 - Housekeeping cell cycle
74 - Extracellular matrix
75 - Housekeeping
76 - Housekeeping regulation
77 - Housekeeping defense
78 - Lymphoid T cells
79 - Lymphoid myeloid
80 - Heart uncharacterized
81 - Vasculature and connective tissue
82 - Lymphoid B cell
83 - Not detected
84 - Epithelium transcription regulation
Tissue group
Any
Adipose tissue
Adrenal gland
Aorta
Bone marrow
Brain
Breast
Cartilage
Cervix
Choroid plexus
Cornea
Ductus deferens
Dura mater
Endometrium
Epididymis
Esophagus
Fallopian tube
Gallbladder
Heart
Kidney
Large intestine
Lens
Liver
Lung
Lymphoid tissue
Male glands
Mesothelial tissue
Mouth
Ovary
Penis
Pineal gland
Pituitary gland
Retina
Salivary gland
Skeletal muscle
Skin
Small intestine
Smooth muscle
Stomach
Synovial tissue
Testis
Thyroid gland
Upper respiratory system
Urinary bladder
Vagus nerve
Category
Tissue enriched
Group enriched
Tissue enhanced
Low tissue specificity
Not detected
Detected in all
Detected in many
Detected in some
Detected in single
Is highest expressed
Brain region
Any
Amygdala
Basal ganglia
Cerebellum
Cerebral cortex
Corpus callosum
Hippocampal formation
Hypothalamus
Midbrain
Olfactory region
Pituitary gland
Pons and medulla
Retina
Spinal cord
Thalamus
Category
Region enriched
Group enriched
Region enhanced
Low region specificity
Not detected
Detected in all
Detected in many
Detected in some
Detected in single
Is highest expressed
Column
Gene
Position
Tissue specific score
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THE PIG PROTEOME
THE PIG ATLAS
TISSUE SPECIFIC PROTEOME
UMAP GENE CLUSTERING
BIOMEDICAL RESEARCH
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4635 GENES FOUND
Gene
Gene
i
Gene name, if available.
Gene synonym (Human ortholog)
Ensembl gene id
Ensembl gene id (Proteincoding human ortholog)
Gene description
Uniprot accession (Human ortholog)
Chromosome
Chromosome position
Related human disease
RNA category pig
RNA pig tissue group specificity
RNA pig tissue group distribution
RNA pig tissue group specificity score
RNA pig tissue group specific NX
RNA pig brain regional specificity
RNA pig brain regional distribution
RNA pig brain regional specificity score
RNA pig brain regional specific pTPM
Annotation
UMAP cluster
Within tissue variation
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1.
Select data columns:
Gene
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Gene
i
Gene name, if available.
Gene synonym (Human ortholog)
Ensembl gene id
Ensembl gene id (Proteincoding human ortholog)
Gene description
Uniprot accession (Human ortholog)
Chromosome
Chromosome position
Related human disease
RNA category pig
Expand
RNA pig tissue group specificity
RNA pig tissue group distribution
RNA pig tissue group specificity score
RNA pig tissue group specific NX
RNA pig brain regional specificity
RNA pig brain regional distribution
RNA pig brain regional specificity score
RNA pig brain regional specific pTPM
Annotation
Expand
UMAP cluster
Within tissue variation
Pig Tissue RNA
Expand
Abdominal adipose tissue [NX]
Adrenal gland [NX]
Amygdala [NX]
Aorta [NX]
Bone marrow [NX]
Breast [NX]
Bronchus [NX]
Bulbourethral gland [NX]
Caudate [NX]
Cecum [NX]
Cerebellum [NX]
Cervix [NX]
Choroid plexus [NX]
Cingulate cortex [NX]
Colon [NX]
Cornea [NX]
Corpus callosum [NX]
Dorsal hippocampus [NX]
Dorsal spinal cord [NX]
Ductus deferens [NX]
Duodenum [NX]
Dura mater [NX]
Ear cartilage [NX]
Endometrium 1 [NX]
Entorhinal cortex [NX]
Epididymis [NX]
Esophagus [NX]
Facial adipose tissue [NX]
Fallopian tube [NX]
Gallbladder [NX]
Heart atrium [NX]
Heart valve [NX]
Heart wall [NX]
Hypothalamus [NX]
Ileum [NX]
Insular cortex [NX]
Jejunum [NX]
Joint cartilage [NX]
Kidney (cortex) [NX]
Kidney (medulla) [NX]
Larynx [NX]
Lens [NX]
Lip [NX]
Liver [NX]
Lung [NX]
Lymph node [NX]
Medulla [NX]
Midbrain [NX]
Motor cortex [NX]
Nasopharynx epithelium [NX]
Occipital cortex [NX]
Olfactory bulb [NX]
Olfactory epithelium [NX]
Oral mucosa [NX]
Ovary [NX]
Penis [NX]
Periaqueductal gray [NX]
Peritoneum [NX]
Pineal gland [NX]
Pituitary gland [NX]
Pleura [NX]
Pons [NX]
Prefrontal cortex [NX]
Prostate [NX]
Putamen [NX]
Rectum [NX]
Retina [NX]
Retrosplenial cortex [NX]
Salivary gland [NX]
Seminal vesicle [NX]
Septum [NX]
Skeletal muscle [NX]
Skin (back) [NX]
Skin (groin) [NX]
Smooth muscle (intestine) [NX]
Somatosensory cortex [NX]
Spleen [NX]
Stomach (lower) [NX]
Stomach (upper) [NX]
Subcutaneous adipose tissue [NX]
Subiculum [NX]
Substantia nigra [NX]
Superior colliculi [NX]
Synovial tissue [NX]
Temporal cortex [NX]
Testis [NX]
Thalamus [NX]
Thymus [NX]
Thyroid gland [NX]
Tongue [NX]
Tonsil [NX]
Trachea [NX]
Urethral gland [NX]
Urinary bladder [NX]
Vagus nerve [NX]
Ventral hippocampus [NX]
Ventral pallidum [NX]
Ventral spinal cord [NX]
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Gene
i
Gene name, if available.
Ensembl
x
Human ortholog
x
Gene description
x
RNA pig tissue group specificity
x
RNA pig tissue group distribution
x
RNA pig tissue group specific NX
x
RPS6KA4
ENSSSCG00000028806
ENSG00000162302
Ribosomal protein S6 kinase A4
Tissue enhanced
Detected in all
stomach:
41.7
RPS6KA5
ENSSSCG00000024377
ENSG00000100784
Ribosomal protein S6 kinase A5
Low tissue specificity
Detected in all
RPS6KL1
ENSSSCG00000002375
ENSG00000198208
Ribosomal protein S6 kinase like 1
Tissue enhanced
Detected in many
brain:
15.1
retina:
14.4
RRAS
ENSSSCG00000003183
ENSG00000126458
RAS related
Tissue enhanced
Detected in all
smooth muscle:
113.4
RREB1
ENSSSCG00000001021
ENSG00000124782
Ras responsive element binding protein 1
Low tissue specificity
Detected in all
RS1
ENSSSCG00000026932
ENSG00000102104
Retinoschisin 1
Tissue enriched
Detected in some
retina:
105.5
RSPH14
ENSSSCG00000010047
ENSG00000100218
Radial spoke head 14 homolog
Tissue enhanced
Detected in some
fallopian tube:
16.3
lung:
13.4
testis:
12.2
upper respiratory system:
39.2
RSPO3
ENSSSCG00000004218
ENSG00000146374
R-spondin-3 precursor
Tissue enhanced
Detected in many
ductus deferens:
44.6
dura mater:
45.6
RTKN
ENSSSCG00000008281
ENSG00000114993
Rhotekin
Tissue enhanced
Detected in many
brain:
53.4
vagus nerve:
52.5
RTKN2
ENSSSCG00000039707
ENSG00000182010
Rhotekin 2
Tissue enhanced
Detected in many
lung:
27.1
lymphoid tissue:
22.1
testis:
13.9
RTL5
ENSSSCG00000020876
ENSG00000242732
Retrotransposon Gag like 5
Group enriched
Detected in many
ductus deferens:
69.6
epididymis:
127.0
male glands:
72.3
RTN1
ENSSSCG00000025013
ENSG00000139970
Reticulon-1 isoform 2
Tissue enhanced
Detected in some
brain:
52.6
pineal gland:
20.2
retina:
11.8
RTN2
ENSSSCG00000036870
ENSG00000125744
Reticulon-2
Tissue enhanced
Detected in all
retina:
27.6
skeletal muscle:
79.7
RTN4RL1
ENSSSCG00000039780
ENSG00000185924
Reticulon 4 receptor like 1
Low tissue specificity
Detected in many
RUNDC3A
ENSSSCG00000017359
ENSG00000108309
RUN domain containing 3A
Tissue enriched
Detected in some
brain:
60.2
RUNDC3B
ENSSSCG00000024485
ENSG00000105784
RUN domain containing 3B
Tissue enhanced
Detected in many
brain:
43.9
lens:
18.3
RUNX1T1
ENSSSCG00000006115
ENSG00000079102
RUNX1 translocation partner 1
Low tissue specificity
Detected in all
RUNX2
ENSSSCG00000001710
ENSG00000124813
Runt related transcription factor 2
Tissue enhanced
Detected in many
ovary:
40.2
stomach:
49.4
RXRA
ENSSSCG00000038220
ENSG00000186350
Retinoid X receptor alpha
Low tissue specificity
Detected in all
RXRG
ENSSSCG00000006328
ENSG00000143171
Retinoic acid receptor RXR-gamma
Tissue enhanced
Detected in all
brain:
29.0
pineal gland:
61.5
RYR2
ENSSSCG00000010142
ENSG00000198626
Ryanodine receptor 2
Tissue enriched
Detected in many
heart:
143.0
S100A1
ENSSSCG00000031053
ENSG00000160678
S100 calcium binding protein A1
Tissue enhanced
Detected in many
brain:
250.1
cartilage:
96.8
pineal gland:
70.9
S100A10
ENSSSCG00000006612
ENSG00000197747
Protein S100-A10
Tissue enhanced
Detected in all
lens:
193.0
S100A13
ENSSSCG00000038991
ENSG00000189171
S100 calcium binding protein A13
Tissue enriched
Detected in all
male glands:
118.5
S100A14
ENSSSCG00000006582
ENSG00000189334
Protein S100-A14
Tissue enhanced
Detected in many
brain:
42.6
cornea:
41.1
mouth:
54.2
stomach:
44.6
S100A3
ENSSSCG00000006579
ENSG00000188015
S100 calcium binding protein A3
Tissue enriched
Detected in some
skin:
126.2
S100A4
ENSSSCG00000006578
ENSG00000196154
Protein S100-A4
Tissue enriched
Detected in many
lens:
255.7
S100A5
ENSSSCG00000006577
ENSG00000196420
S100 calcium binding protein A5
Tissue enriched
Detected in some
brain:
19.4
S100A6
ENSSSCG00000021084
ENSG00000197956
Protein S100-A6
Tissue enhanced
Detected in many
cornea:
159.7
lens:
261.3
S100Z
ENSSSCG00000014092
ENSG00000171643
S100 calcium binding protein Z
Low tissue specificity
Detected in all
S1PR1
ENSSSCG00000029849
ENSG00000170989
Sphingosine-1-phosphate receptor 1
Low tissue specificity
Detected in all
S1PR3
ENSSSCG00000009580
ENSG00000213694
Sphingosine-1-phosphate receptor 3
Tissue enhanced
Detected in many
lens:
30.8
ovary:
50.9
S1PR5
ENSSSCG00000028460
ENSG00000180739
Sphingosine 1-phosphate receptor 5
Tissue enhanced
Detected in many
brain:
36.7
skin:
14.4
SACS
ENSSSCG00000035493
ENSG00000151835
Sacsin molecular chaperone
Tissue enhanced
Detected in all
brain:
25.8
SAG
ENSSSCG00000016301
ENSG00000130561
S-arrestin
Tissue enriched
Detected in some
retina:
341.4
SALL1
ENSSSCG00000002836
ENSG00000103449
Spalt like transcription factor 1
Tissue enhanced
Detected in many
kidney:
21.5
lens:
43.4
liver:
21.1
pineal gland:
26.1
thyroid gland:
31.4
SALL3
ENSSSCG00000004858
ENSG00000256463
Spalt like transcription factor 3
Tissue enhanced
Detected in some
brain:
14.0
heart:
12.0
male glands:
55.2
SAMD10
ENSSSCG00000034186
ENSG00000130590
Sterile alpha motif domain containing 10
Tissue enhanced
Detected in many
male glands:
24.0
SAMD11
ENSSSCG00000033509
ENSG00000187634
Sterile alpha motif domain containing 11
Tissue enriched
Detected in many
retina:
108.3
SAMD12
ENSSSCG00000036553
ENSG00000177570
Sterile alpha motif domain containing 12
Tissue enhanced
Detected in many
brain:
27.0
SAMD14
ENSSSCG00000017585
ENSG00000167100
Sterile alpha motif domain containing 14
Tissue enhanced
Detected in many
brain:
24.7
SAMD15
ENSSSCG00000002400
ENSG00000100583
Sterile alpha motif domain containing 15
Tissue enhanced
Detected in many
fallopian tube:
29.3
testis:
46.2
upper respiratory system:
21.6
SAMD4A
ENSSSCG00000023408
ENSG00000020577
Sterile alpha motif domain containing 4A
Tissue enhanced
Detected in many
testis:
79.6
SAMD5
ENSSSCG00000004112
ENSG00000203727
Sterile alpha motif domain containing 5
Tissue enhanced
Detected in many
vagus nerve:
47.2
SAP30
ENSSSCG00000030118
ENSG00000164105
Sin3A associated protein 30
Low tissue specificity
Detected in all
SAPCD1
ENSSSCG00000036076
ENSG00000228727
Suppressor APC domain containing 1
Tissue enriched
Detected in many
lens:
82.1
SAPCD2
ENSSSCG00000032279
ENSG00000186193
Suppressor APC domain containing 2
Tissue enhanced
Detected in some
large intestine:
20.6
skin:
7.7
small intestine:
10.7
SASH1
ENSSSCG00000033175
ENSG00000111961
SAM and SH3 domain containing 1
Low tissue specificity
Detected in all
SC5D
ENSSSCG00000028517
ENSG00000109929
Sterol-C5-desaturase
Tissue enhanced
Detected in all
brain:
42.8
liver:
49.5
male glands:
37.0
SCARA3
ENSSSCG00000020846
ENSG00000168077
Scavenger receptor class A member 3
Tissue enhanced
Detected in many
cartilage:
133.2
penis:
53.5
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