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Human disease related genes
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UMAP gene cluster
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Subclass
Class
Biological process
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Disease
Keyword
Chromosome
1
2
3
4
5
6
7
8
9
10
11
12
13
14
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16
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18
MT
Unmapped
X
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External id
Variability
Variable
Not variable
Tissue
Any
Adipose tissue
Brain
Cartilage
Heart
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Lymphoid tissue
Male glands
Mesothelial tissue
Mouth
Skin
Small intestine
Stomach 1
Upper respiratory system
Cluster
1 - Brain neurotransmission
2 - Brain neurotransmission
3 - Brain cellular structure
4 - Brain development
5 - Intracellular signalling
6 - Brain uncharacterized
7 - Retinal
8 - Neurohormonal
9 - Testis spermatogenesis
10 - Housekeeping transcription
11 - Testis uncharacterized
12 - Metabolic
13 - Testis sperm
14 - Low abundant uncharacterized
15 - Testis uncharacterized
16 - Aorta uncharacterized
17 - Cilium structure
18 - Low abundant uncharacterized
19 - Housekeeping mitochondrial
20 - Hormonal
21 - Low abundant uncharacterized
22 - Housekeeping transcription
23 - Cilium structure
24 - Low abundant uncharacterized
25 - Low abundant uncharacterized
26 - Low abundant uncharacterized
27 - Low abundant uncharacterized
28 - Housekeeping mitochondrial translation
29 - Male tissue bacterial defense
30 - Housekeeping structural
31 - Housekeeping uncharacterized
32 - Transport
33 - Lens
34 - Prostate uncharacterized
35 - Low abundant uncharacterized
36 - Receptors uncharacterized
37 - Olfactory bulb
38 - Lung and thyroid development
39 - Kidney transport
40 - Testis
41 - Low abundant uncharacterized
42 - Low abundant uncharacterized
43 - Breast uncharacterized
44 - Housekeeping
45 - Thymus uncharacterized
46 - Skeletal muscle contraction
47 - Spleen uncharacterized
48 - Low abundant uncharacterized
49 - Heart contraction
50 - Muscle contraction
51 - Liver and kidney
52 - Housekeeping
53 - Housekeeping mitochondrial
54 - Interferons
55 - Low abundant uncharacterized
56 - Low abundant uncharacterized
57 - Skin
58 - Immune cells
59 - Squamous epithelium
60 - Not detected
61 - Enzymes and secretion
62 - Squamous epithelium
63 - Small intestine
64 - Gastrointestinal
65 - Epithelium
66 - Housekeeping mRNA
67 - Gastrointestinal
68 - Housekeeping protein processing
69 - Housekeeping
70 - Housekeeping
71 - Housekeeping regulation
72 - Digestive and respiratory defense
73 - Housekeeping cell cycle
74 - Extracellular matrix
75 - Housekeeping
76 - Housekeeping regulation
77 - Housekeeping defense
78 - Lymphoid T cells
79 - Lymphoid myeloid
80 - Heart uncharacterized
81 - Vasculature and connective tissue
82 - Lymphoid B cell
83 - Not detected
84 - Epithelium transcription regulation
Tissue group
Any
Adipose tissue
Adrenal gland
Aorta
Bone marrow
Brain
Breast
Cartilage
Cervix
Choroid plexus
Cornea
Ductus deferens
Dura mater
Endometrium
Epididymis
Esophagus
Fallopian tube
Gallbladder
Heart
Kidney
Large intestine
Lens
Liver
Lung
Lymphoid tissue
Male glands
Mesothelial tissue
Mouth
Ovary
Penis
Pineal gland
Pituitary gland
Retina
Salivary gland
Skeletal muscle
Skin
Small intestine
Smooth muscle
Stomach
Synovial tissue
Testis
Thyroid gland
Upper respiratory system
Urinary bladder
Vagus nerve
Category
Tissue enriched
Group enriched
Tissue enhanced
Low tissue specificity
Not detected
Detected in all
Detected in many
Detected in some
Detected in single
Is highest expressed
Brain region
Any
Amygdala
Basal ganglia
Cerebellum
Cerebral cortex
Corpus callosum
Hippocampal formation
Hypothalamus
Midbrain
Olfactory region
Pituitary gland
Pons and medulla
Retina
Spinal cord
Thalamus
Category
Region enriched
Group enriched
Region enhanced
Low region specificity
Not detected
Detected in all
Detected in many
Detected in some
Detected in single
Is highest expressed
Column
Gene
Position
Tissue specific score
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THE PIG PROTEOME
THE PIG ATLAS
TISSUE SPECIFIC PROTEOME
UMAP GENE CLUSTERING
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4635 GENES FOUND
Gene
Gene
i
Gene name, if available.
Gene synonym (Human ortholog)
Ensembl gene id
Ensembl gene id (Proteincoding human ortholog)
Gene description
Uniprot accession (Human ortholog)
Chromosome
Chromosome position
Related human disease
RNA category pig
RNA pig tissue group specificity
RNA pig tissue group distribution
RNA pig tissue group specificity score
RNA pig tissue group specific NX
RNA pig brain regional specificity
RNA pig brain regional distribution
RNA pig brain regional specificity score
RNA pig brain regional specific pTPM
Annotation
UMAP cluster
Within tissue variation
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1.
Select data columns:
Gene
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Gene
i
Gene name, if available.
Gene synonym (Human ortholog)
Ensembl gene id
Ensembl gene id (Proteincoding human ortholog)
Gene description
Uniprot accession (Human ortholog)
Chromosome
Chromosome position
Related human disease
RNA category pig
Expand
RNA pig tissue group specificity
RNA pig tissue group distribution
RNA pig tissue group specificity score
RNA pig tissue group specific NX
RNA pig brain regional specificity
RNA pig brain regional distribution
RNA pig brain regional specificity score
RNA pig brain regional specific pTPM
Annotation
Expand
UMAP cluster
Within tissue variation
Pig Tissue RNA
Expand
Abdominal adipose tissue [NX]
Adrenal gland [NX]
Amygdala [NX]
Aorta [NX]
Bone marrow [NX]
Breast [NX]
Bronchus [NX]
Bulbourethral gland [NX]
Caudate [NX]
Cecum [NX]
Cerebellum [NX]
Cervix [NX]
Choroid plexus [NX]
Cingulate cortex [NX]
Colon [NX]
Cornea [NX]
Corpus callosum [NX]
Dorsal hippocampus [NX]
Dorsal spinal cord [NX]
Ductus deferens [NX]
Duodenum [NX]
Dura mater [NX]
Ear cartilage [NX]
Endometrium 1 [NX]
Entorhinal cortex [NX]
Epididymis [NX]
Esophagus [NX]
Facial adipose tissue [NX]
Fallopian tube [NX]
Gallbladder [NX]
Heart atrium [NX]
Heart valve [NX]
Heart wall [NX]
Hypothalamus [NX]
Ileum [NX]
Insular cortex [NX]
Jejunum [NX]
Joint cartilage [NX]
Kidney (cortex) [NX]
Kidney (medulla) [NX]
Larynx [NX]
Lens [NX]
Lip [NX]
Liver [NX]
Lung [NX]
Lymph node [NX]
Medulla [NX]
Midbrain [NX]
Motor cortex [NX]
Nasopharynx epithelium [NX]
Occipital cortex [NX]
Olfactory bulb [NX]
Olfactory epithelium [NX]
Oral mucosa [NX]
Ovary [NX]
Penis [NX]
Periaqueductal gray [NX]
Peritoneum [NX]
Pineal gland [NX]
Pituitary gland [NX]
Pleura [NX]
Pons [NX]
Prefrontal cortex [NX]
Prostate [NX]
Putamen [NX]
Rectum [NX]
Retina [NX]
Retrosplenial cortex [NX]
Salivary gland [NX]
Seminal vesicle [NX]
Septum [NX]
Skeletal muscle [NX]
Skin (back) [NX]
Skin (groin) [NX]
Smooth muscle (intestine) [NX]
Somatosensory cortex [NX]
Spleen [NX]
Stomach (lower) [NX]
Stomach (upper) [NX]
Subcutaneous adipose tissue [NX]
Subiculum [NX]
Substantia nigra [NX]
Superior colliculi [NX]
Synovial tissue [NX]
Temporal cortex [NX]
Testis [NX]
Thalamus [NX]
Thymus [NX]
Thyroid gland [NX]
Tongue [NX]
Tonsil [NX]
Trachea [NX]
Urethral gland [NX]
Urinary bladder [NX]
Vagus nerve [NX]
Ventral hippocampus [NX]
Ventral pallidum [NX]
Ventral spinal cord [NX]
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Gene
i
Gene name, if available.
Ensembl
x
Human ortholog
x
Gene description
x
RNA pig tissue group specificity
x
RNA pig tissue group distribution
x
RNA pig tissue group specific NX
x
PARVB
ENSSSCG00000000024
ENSG00000188677
Parvin beta
Tissue enhanced
Detected in many
skeletal muscle:
39.7
PAX2
ENSSSCG00000010556
ENSG00000075891
Paired box 2
Tissue enhanced
Detected in some
ductus deferens:
41.9
epididymis:
182.3
kidney:
41.0
male glands:
82.9
PAX3
ENSSSCG00000028418
ENSG00000135903
Paired box 3
Tissue enhanced
Detected in some
mouth:
18.8
pineal gland:
7.7
upper respiratory system:
37.7
PAX5
ENSSSCG00000036086
ENSG00000196092
Paired box 5
Tissue enhanced
Detected in some
lymphoid tissue:
69.4
upper respiratory system:
37.6
PAX6
ENSSSCG00000013320
ENSG00000007372
Paired box protein Pax-6 isoform 1
Tissue enhanced
Detected in some
cornea:
121.0
lens:
48.8
retina:
31.4
PAX7
ENSSSCG00000034627
ENSG00000009709
Paired box 7
Tissue enhanced
Detected in some
pituitary gland:
23.9
skeletal muscle:
8.1
upper respiratory system:
26.1
PAXIP1
ENSSSCG00000025221
ENSG00000157212
PAX interacting protein 1
Low tissue specificity
Detected in all
PBX1
ENSSSCG00000006331
ENSG00000185630
PBX homeobox 1
Low tissue specificity
Detected in all
PBX3
ENSSSCG00000005604
ENSG00000167081
PBX homeobox 3
Tissue enhanced
Detected in all
brain:
73.0
PBX4
ENSSSCG00000013933
ENSG00000105717
PBX homeobox 4
Tissue enhanced
Detected in many
testis:
41.1
PBXIP1
ENSSSCG00000006540
ENSG00000163346
PBX homeobox interacting protein 1
Low tissue specificity
Detected in all
PCBD1
ENSSSCG00000010275
ENSG00000166228
Pterin-4-alpha-carbinolamine dehydratase
Tissue enhanced
Detected in all
liver:
105.1
PCBP3
ENSSSCG00000023041
ENSG00000183570
Poly(rC) binding protein 3
Group enriched
Detected in some
brain:
48.7
pineal gland:
16.8
retina:
65.0
testis:
28.0
PCBP4
ENSSSCG00000028446
ENSG00000090097
Poly(rC) binding protein 4
Tissue enhanced
Detected in many
brain:
47.4
pineal gland:
60.2
retina:
87.1
vagus nerve:
53.4
PCDH10
ENSSSCG00000036125
ENSG00000138650
Protocadherin 10
Tissue enhanced
Detected in some
adrenal gland:
9.6
brain:
27.1
fallopian tube:
7.6
PCDH15
ENSSSCG00000010426
ENSG00000150275
Protocadherin related 15
Tissue enhanced
Detected in some
lens:
24.5
ovary:
13.8
retina:
67.0
PCDH17
ENSSSCG00000009446
ENSG00000118946
Protocadherin 17
Tissue enhanced
Detected in many
brain:
36.9
PCDH19
ENSSSCG00000012479
ENSG00000165194
Protocadherin 19
Tissue enhanced
Detected in many
lens:
38.0
PCDH8
ENSSSCG00000009445
ENSG00000136099
Protocadherin 8
Tissue enhanced
Detected in some
brain:
22.3
retina:
7.1
testis:
5.1
PCDH9
ENSSSCG00000038842
ENSG00000184226
Protocadherin 9
Group enriched
Detected in many
brain:
123.4
pineal gland:
30.8
PCED1B
ENSSSCG00000000811
ENSG00000179715
PC-esterase domain containing 1B
Tissue enhanced
Detected in many
endometrium:
46.4
lymphoid tissue:
51.7
PCOLCE
ENSSSCG00000027466
ENSG00000106333
Procollagen C-endopeptidase enhancer
Tissue enhanced
Detected in many
cartilage:
123.2
synovial tissue:
132.1
PCOLCE2
ENSSSCG00000011683
ENSG00000163710
Procollagen C-endopeptidase enhancer 2
Tissue enriched
Detected in many
ovary:
107.9
PCP2
ENSSSCG00000037188
ENSG00000174788
Purkinje cell protein 2
Tissue enriched
Detected in some
pineal gland:
127.4
PCSK1
ENSSSCG00000014169
ENSG00000175426
Neuroendocrine convertase 1 precursor
Group enriched
Detected in some
brain:
28.5
pineal gland:
47.8
pituitary gland:
42.7
PCSK2
ENSSSCG00000007083
ENSG00000125851
Neuroendocrine convertase 2 precursor
Tissue enhanced
Detected in some
brain:
38.0
pituitary gland:
51.1
thyroid gland:
19.5
PCSK6
ENSSSCG00000005785
ENSG00000140479
Proprotein convertase subtilisin/kexin type 6
Tissue enhanced
Detected in many
brain:
47.5
liver:
57.1
synovial tissue:
32.3
PCSK7
ENSSSCG00000015072
ENSG00000160613
Proprotein convertase subtilisin/kexin type 7
Tissue enhanced
Detected in all
stomach:
47.6
PDC
ENSSSCG00000015578
ENSG00000116703
Phosducin
Group enriched
Detected in some
pineal gland:
122.5
retina:
222.0
PDE10A
ENSSSCG00000004027
ENSG00000112541
Phosphodiesterase 10A
Tissue enhanced
Detected in many
brain:
69.6
PDE1B
ENSSSCG00000000297
ENSG00000123360
Phosphodiesterase 1B
Tissue enriched
Detected in many
brain:
80.9
PDE1C
ENSSSCG00000016668
ENSG00000154678
Phosphodiesterase 1C
Tissue enhanced
Detected in many
brain:
29.8
pineal gland:
34.2
PDE3A
ENSSSCG00000028662
ENSG00000172572
CGMP-inhibited 3',5'-cyclic phosphodiesterase A
Tissue enhanced
Detected in many
heart:
78.3
PDE4A
ENSSSCG00000013642
ENSG00000065989
CAMP-specific 3',5'-cyclic phosphodiesterase 4A
Tissue enhanced
Detected in many
male glands:
60.9
skeletal muscle:
47.4
PDE5A
ENSSSCG00000009106
ENSG00000138735
Phosphodiesterase 5A
Tissue enhanced
Detected in many
smooth muscle:
69.7
PDE7B
ENSSSCG00000004165
ENSG00000171408
Phosphodiesterase 7B
Low tissue specificity
Detected in all
PDGFC
ENSSSCG00000024960
ENSG00000145431
Platelet derived growth factor C
Low tissue specificity
Detected in many
PDGFD
ENSSSCG00000014994
ENSG00000170962
Platelet derived growth factor D
Low tissue specificity
Detected in all
PDGFRA
ENSSSCG00000008841
ENSG00000134853
Platelet-derived growth factor receptor alpha precursor
Tissue enhanced
Detected in all
cartilage:
67.5
ovary:
55.7
PDGFRB
ENSSSCG00000022741
ENSG00000113721
Platelet derived growth factor receptor beta
Low tissue specificity
Detected in many
PDGFRL
ENSSSCG00000006988
ENSG00000104213
Platelet derived growth factor receptor like
Tissue enhanced
Detected in many
cornea:
98.9
PDLIM1
ENSSSCG00000010493
ENSG00000107438
PDZ and LIM domain protein 1
Low tissue specificity
Detected in many
PDLIM7
ENSSSCG00000040507
ENSG00000196923
PDZ and LIM domain 7
Tissue enhanced
Detected in all
skeletal muscle:
228.4
smooth muscle:
135.2
PDP1
ENSSSCG00000006107
ENSG00000164951
Pyruvate dehyrogenase phosphatase catalytic subunit 1
Tissue enhanced
Detected in all
brain:
54.0
PDXK
ENSSSCG00000034758
ENSG00000160209
Pyridoxal kinase
Tissue enhanced
Detected in all
brain:
25.4
PDXP
ENSSSCG00000034632
ENSG00000241360
Pyridoxal phosphatase
Tissue enhanced
Detected in many
brain:
33.1
PDZD2
ENSSSCG00000016810
ENSG00000133401
PDZ domain containing 2
Low tissue specificity
Detected in all
PDZD4
ENSSSCG00000012785
ENSG00000067840
PDZ domain containing 4
Tissue enriched
Detected in some
brain:
40.9
PDZRN3
ENSSSCG00000011521
ENSG00000121440
PDZ domain containing ring finger 3
Low tissue specificity
Detected in many
PDZRN4
ENSSSCG00000000791
ENSG00000165966
PDZ domain containing ring finger 4
Tissue enhanced
Detected in many
choroid plexus:
19.5
skin:
31.0
smooth muscle:
23.3
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