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Human disease related genes
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UMAP gene cluster
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Subclass
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Biological process
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Disease
Keyword
Chromosome
1
2
3
4
5
6
7
8
9
10
11
12
13
14
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18
MT
Unmapped
X
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External id
Variability
Variable
Not variable
Tissue
Any
Adipose tissue
Brain
Cartilage
Heart
Kidney
Large intestine
Lymphoid tissue
Male glands
Mesothelial tissue
Mouth
Skin
Small intestine
Stomach 1
Upper respiratory system
Cluster
1 - Brain neurotransmission
2 - Brain neurotransmission
3 - Brain cellular structure
4 - Brain development
5 - Intracellular signalling
6 - Brain uncharacterized
7 - Retinal
8 - Neurohormonal
9 - Testis spermatogenesis
10 - Housekeeping transcription
11 - Testis uncharacterized
12 - Metabolic
13 - Testis sperm
14 - Low abundant uncharacterized
15 - Testis uncharacterized
16 - Aorta uncharacterized
17 - Cilium structure
18 - Low abundant uncharacterized
19 - Housekeeping mitochondrial
20 - Hormonal
21 - Low abundant uncharacterized
22 - Housekeeping transcription
23 - Cilium structure
24 - Low abundant uncharacterized
25 - Low abundant uncharacterized
26 - Low abundant uncharacterized
27 - Low abundant uncharacterized
28 - Housekeeping mitochondrial translation
29 - Male tissue bacterial defense
30 - Housekeeping structural
31 - Housekeeping uncharacterized
32 - Transport
33 - Lens
34 - Prostate uncharacterized
35 - Low abundant uncharacterized
36 - Receptors uncharacterized
37 - Olfactory bulb
38 - Lung and thyroid development
39 - Kidney transport
40 - Testis
41 - Low abundant uncharacterized
42 - Low abundant uncharacterized
43 - Breast uncharacterized
44 - Housekeeping
45 - Thymus uncharacterized
46 - Skeletal muscle contraction
47 - Spleen uncharacterized
48 - Low abundant uncharacterized
49 - Heart contraction
50 - Muscle contraction
51 - Liver and kidney
52 - Housekeeping
53 - Housekeeping mitochondrial
54 - Interferons
55 - Low abundant uncharacterized
56 - Low abundant uncharacterized
57 - Skin
58 - Immune cells
59 - Squamous epithelium
60 - Not detected
61 - Enzymes and secretion
62 - Squamous epithelium
63 - Small intestine
64 - Gastrointestinal
65 - Epithelium
66 - Housekeeping mRNA
67 - Gastrointestinal
68 - Housekeeping protein processing
69 - Housekeeping
70 - Housekeeping
71 - Housekeeping regulation
72 - Digestive and respiratory defense
73 - Housekeeping cell cycle
74 - Extracellular matrix
75 - Housekeeping
76 - Housekeeping regulation
77 - Housekeeping defense
78 - Lymphoid T cells
79 - Lymphoid myeloid
80 - Heart uncharacterized
81 - Vasculature and connective tissue
82 - Lymphoid B cell
83 - Not detected
84 - Epithelium transcription regulation
Tissue group
Any
Adipose tissue
Adrenal gland
Aorta
Bone marrow
Brain
Breast
Cartilage
Cervix
Choroid plexus
Cornea
Ductus deferens
Dura mater
Endometrium
Epididymis
Esophagus
Fallopian tube
Gallbladder
Heart
Kidney
Large intestine
Lens
Liver
Lung
Lymphoid tissue
Male glands
Mesothelial tissue
Mouth
Ovary
Penis
Pineal gland
Pituitary gland
Retina
Salivary gland
Skeletal muscle
Skin
Small intestine
Smooth muscle
Stomach
Synovial tissue
Testis
Thyroid gland
Upper respiratory system
Urinary bladder
Vagus nerve
Category
Tissue enriched
Group enriched
Tissue enhanced
Low tissue specificity
Not detected
Detected in all
Detected in many
Detected in some
Detected in single
Is highest expressed
Brain region
Any
Amygdala
Basal ganglia
Cerebellum
Cerebral cortex
Corpus callosum
Hippocampal formation
Hypothalamus
Midbrain
Olfactory region
Pituitary gland
Pons and medulla
Retina
Spinal cord
Thalamus
Category
Region enriched
Group enriched
Region enhanced
Low region specificity
Not detected
Detected in all
Detected in many
Detected in some
Detected in single
Is highest expressed
Column
Gene
Position
Tissue specific score
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THE PIG PROTEOME
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595 GENES FOUND
Gene
Gene
i
Gene name, if available.
Gene synonym (Human ortholog)
Ensembl gene id
Ensembl gene id (Proteincoding human ortholog)
Gene description
Uniprot accession (Human ortholog)
Chromosome
Chromosome position
Related human disease
RNA category pig
RNA pig tissue group specificity
RNA pig tissue group distribution
RNA pig tissue group specificity score
RNA pig tissue group specific NX
RNA pig brain regional specificity
RNA pig brain regional distribution
RNA pig brain regional specificity score
RNA pig brain regional specific pTPM
Annotation
UMAP cluster
Within tissue variation
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Select data columns:
Gene
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Gene
i
Gene name, if available.
Gene synonym (Human ortholog)
Ensembl gene id
Ensembl gene id (Proteincoding human ortholog)
Gene description
Uniprot accession (Human ortholog)
Chromosome
Chromosome position
Related human disease
RNA category pig
Expand
RNA pig tissue group specificity
RNA pig tissue group distribution
RNA pig tissue group specificity score
RNA pig tissue group specific NX
RNA pig brain regional specificity
RNA pig brain regional distribution
RNA pig brain regional specificity score
RNA pig brain regional specific pTPM
Annotation
Expand
UMAP cluster
Within tissue variation
Pig Tissue RNA
Expand
Abdominal adipose tissue [NX]
Adrenal gland [NX]
Amygdala [NX]
Aorta [NX]
Bone marrow [NX]
Breast [NX]
Bronchus [NX]
Bulbourethral gland [NX]
Caudate [NX]
Cecum [NX]
Cerebellum [NX]
Cervix [NX]
Choroid plexus [NX]
Cingulate cortex [NX]
Colon [NX]
Cornea [NX]
Corpus callosum [NX]
Dorsal hippocampus [NX]
Dorsal spinal cord [NX]
Ductus deferens [NX]
Duodenum [NX]
Dura mater [NX]
Ear cartilage [NX]
Endometrium 1 [NX]
Entorhinal cortex [NX]
Epididymis [NX]
Esophagus [NX]
Facial adipose tissue [NX]
Fallopian tube [NX]
Gallbladder [NX]
Heart atrium [NX]
Heart valve [NX]
Heart wall [NX]
Hypothalamus [NX]
Ileum [NX]
Insular cortex [NX]
Jejunum [NX]
Joint cartilage [NX]
Kidney (cortex) [NX]
Kidney (medulla) [NX]
Larynx [NX]
Lens [NX]
Lip [NX]
Liver [NX]
Lung [NX]
Lymph node [NX]
Medulla [NX]
Midbrain [NX]
Motor cortex [NX]
Nasopharynx epithelium [NX]
Occipital cortex [NX]
Olfactory bulb [NX]
Olfactory epithelium [NX]
Oral mucosa [NX]
Ovary [NX]
Penis [NX]
Periaqueductal gray [NX]
Peritoneum [NX]
Pineal gland [NX]
Pituitary gland [NX]
Pleura [NX]
Pons [NX]
Prefrontal cortex [NX]
Prostate [NX]
Putamen [NX]
Rectum [NX]
Retina [NX]
Retrosplenial cortex [NX]
Salivary gland [NX]
Seminal vesicle [NX]
Septum [NX]
Skeletal muscle [NX]
Skin (back) [NX]
Skin (groin) [NX]
Smooth muscle (intestine) [NX]
Somatosensory cortex [NX]
Spleen [NX]
Stomach (lower) [NX]
Stomach (upper) [NX]
Subcutaneous adipose tissue [NX]
Subiculum [NX]
Substantia nigra [NX]
Superior colliculi [NX]
Synovial tissue [NX]
Temporal cortex [NX]
Testis [NX]
Thalamus [NX]
Thymus [NX]
Thyroid gland [NX]
Tongue [NX]
Tonsil [NX]
Trachea [NX]
Urethral gland [NX]
Urinary bladder [NX]
Vagus nerve [NX]
Ventral hippocampus [NX]
Ventral pallidum [NX]
Ventral spinal cord [NX]
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Gene
i
Gene name, if available.
Ensembl
x
Human ortholog
x
Gene description
x
RNA pig tissue group specificity
x
RNA pig tissue group distribution
x
RNA pig tissue group specific NX
x
SH3PXD2B
ENSSSCG00000027378
ENSG00000174705
SH3 and PX domains 2B
Low tissue specificity
Detected in all
SHAS2
ENSSSCG00000005992
ENSG00000170961
Hyaluronan synthase 2
Tissue enhanced
Detected in all
ovary:
33.1
SKI
ENSSSCG00000040944
ENSG00000157933
SKI proto-oncogene
Low tissue specificity
Detected in all
SLC27A3
ENSSSCG00000006569
ENSG00000143554
Solute carrier family 27 member 3
Tissue enhanced
Detected in many
epididymis:
18.0
mesothelial tissue:
14.5
SLC2A4
ENSSSCG00000023915
ENSG00000181856
Solute carrier family 2, facilitated glucose transporter member 4
Tissue enhanced
Detected in many
heart:
43.0
skeletal muscle:
81.6
SLC38A2
ENSSSCG00000000808
ENSG00000134294
Sodium-coupled neutral amino acid transporter 2
Low tissue specificity
Detected in all
SLC49A3
ENSSSCG00000026084
ENSG00000169026
Solute carrier family 49 member 3
Low tissue specificity
Detected in many
SLMAP
ENSSSCG00000038873
ENSG00000163681
Sarcolemma associated protein
Tissue enhanced
Detected in all
smooth muscle:
94.3
SMAD6
ENSSSCG00000004948
ENSG00000137834
SMAD family member 6
Low tissue specificity
Detected in many
SMTN
ENSSSCG00000010017
ENSG00000183963
Smoothelin
Tissue enhanced
Detected in many
cervix:
122.7
smooth muscle:
139.9
SNAI1
ENSSSCG00000032613
ENSG00000124216
Snail family transcriptional repressor 1
Tissue enhanced
Detected in many
mesothelial tissue:
31.7
ovary:
21.2
SNAI2
ENSSSCG00000039568
ENSG00000019549
Snail family transcriptional repressor 2
Tissue enhanced
Detected in many
bone marrow:
35.6
cartilage:
27.5
SNED1
ENSSSCG00000016381
ENSG00000162804
Sushi, nidogen and EGF like domains 1
Tissue enhanced
Detected in many
cartilage:
74.6
synovial tissue:
37.6
SNTB2
ENSSSCG00000028109
ENSG00000168807
Syntrophin beta 2
Low tissue specificity
Detected in all
SNX18
ENSSSCG00000031337
ENSG00000178996
Sorting nexin 18
Low tissue specificity
Detected in all
SNX21
ENSSSCG00000007425
ENSG00000124104
Sorting nexin family member 21
Low tissue specificity
Detected in all
SNX33
ENSSSCG00000001875
ENSG00000173548
Sorting nexin 33
Low tissue specificity
Detected in all
SNX7
ENSSSCG00000006877
ENSG00000162627
Sorting nexin 7
Low tissue specificity
Detected in all
SOD3
ENSSSCG00000028814
ENSG00000109610
Superoxide dismutase 3
Tissue enhanced
Detected in many
cartilage:
162.0
ovary:
83.5
SORBS3
ENSSSCG00000009626
ENSG00000120896
Sorbin and SH3 domain containing 3
Low tissue specificity
Detected in all
SPON2
ENSSSCG00000039488
ENSG00000159674
Spondin 2
Tissue enhanced
Detected in many
cartilage:
86.5
SPRY1
ENSSSCG00000009083
ENSG00000164056
Protein sprouty homolog 1
Low tissue specificity
Detected in all
SPSB2
ENSSSCG00000025460
ENSG00000111671
SPRY domain-containing SOCS box protein 2
Tissue enhanced
Detected in all
male glands:
30.4
SPSB4
ENSSSCG00000034369
ENSG00000175093
SplA/ryanodine receptor domain and SOCS box containing 4
Tissue enhanced
Detected in many
heart:
19.7
large intestine:
18.1
SRF
ENSSSCG00000001661
ENSG00000112658
Serum response factor
Tissue enhanced
Detected in all
smooth muscle:
54.2
SRPX
ENSSSCG00000012234
ENSG00000101955
Sushi repeat containing protein, X-linked
Low tissue specificity
Detected in all
SRPX2
ENSSSCG00000012482
ENSG00000102359
Sushi repeat containing protein, X-linked 2
Tissue enriched
Detected in many
cartilage:
73.6
SSC5D
ENSSSCG00000037450
ENSG00000179954
Scavenger receptor cysteine rich family member with 5 domains
Tissue enhanced
Detected in all
adipose tissue:
52.0
cartilage:
57.7
ST6GALNAC2
ENSSSCG00000017177
ENSG00000070731
ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
Low tissue specificity
Detected in many
STAB1
ENSSSCG00000011443
ENSG00000010327
Stabilin 1
Tissue enhanced
Detected in many
synovial tissue:
60.8
STARD13
ENSSSCG00000009348
ENSG00000133121
StAR related lipid transfer domain containing 13
Tissue enhanced
Detected in all
cartilage:
61.3
STOM
ENSSSCG00000036639
ENSG00000148175
Stomatin
Low tissue specificity
Detected in all
SULT1A3
ENSSSCG00000021557
ENSG00000196502,ENSG00000197165,ENSG00000213648,ENSG00000261052
Sulfotransferase 1A3
Tissue enhanced
Detected in many
adipose tissue:
70.7
cervix:
81.1
SULT1C4
ENSSSCG00000025836
ENSG00000198075
Sulfotransferase family 1C member 4
Low tissue specificity
Detected in all
SVEP1
ENSSSCG00000005455
ENSG00000165124
Sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
Low tissue specificity
Detected in many
SVIL
ENSSSCG00000011022
ENSG00000197321
Supervillin
Tissue enhanced
Detected in all
skeletal muscle:
83.5
smooth muscle:
95.6
SYNM
ENSSSCG00000035223
ENSG00000182253
Synemin
Tissue enriched
Detected in many
smooth muscle:
222.0
SYNPO2
ENSSSCG00000009111
ENSG00000172403
Synaptopodin 2
Tissue enhanced
Detected in many
smooth muscle:
198.1
TAGLN
ENSSSCG00000015073
ENSG00000149591
Transgelin
Tissue enhanced
Detected in many
smooth muscle:
633.1
TBX1
ENSSSCG00000037762
ENSG00000184058
T-box 1
Tissue enhanced
Detected in many
mouth:
31.0
skin:
39.2
TBX2
ENSSSCG00000027060
ENSG00000121068
T-box transcription factor TBX2
Tissue enhanced
Detected in many
male glands:
41.4
TCF21
ENSSSCG00000033258
ENSG00000118526
Transcription factor 21
Tissue enhanced
Detected in many
urinary bladder:
18.7
TCF7L1
ENSSSCG00000008241
ENSG00000152284
Transcription factor 7 like 1
Low tissue specificity
Detected in all
TEAD1
ENSSSCG00000013399
ENSG00000187079
Transcriptional enhancer factor TEF-1
Tissue enhanced
Detected in all
skeletal muscle:
79.7
TES
ENSSSCG00000040344
ENSG00000135269
Testin
Tissue enhanced
Detected in many
cervix:
31.2
smooth muscle:
58.0
TFEB
ENSSSCG00000001621
ENSG00000112561
Transcription factor EB
Low tissue specificity
Detected in all
TFPI2
ENSSSCG00000015322
ENSG00000105825
Tissue factor pathway inhibitor 2
Tissue enhanced
Detected in many
adipose tissue:
67.0
ovary:
75.3
TGFB1I1
ENSSSCG00000035952
ENSG00000140682
Transforming growth factor beta 1 induced transcript 1
Tissue enhanced
Detected in many
cervix:
62.0
smooth muscle:
86.2
TGFBI
ENSSSCG00000014316
ENSG00000120708
Transforming growth factor beta induced
Tissue enhanced
Detected in many
cartilage:
147.5
cornea:
213.4
TGFBR2
ENSSSCG00000011226
ENSG00000163513
Transforming growth factor beta receptor 2
Tissue enhanced
Detected in many
cartilage:
107.0
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