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Human disease related genes
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UMAP gene cluster
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Keyword
Chromosome
1
2
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5
6
7
8
9
10
11
12
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14
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MT
Unmapped
X
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External id
Variability
Variable
Not variable
Tissue
Any
Adipose tissue
Brain
Cartilage
Heart
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Large intestine
Lymphoid tissue
Male glands
Mesothelial tissue
Mouth
Skin
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Stomach 1
Upper respiratory system
Cluster
1 - Brain neurotransmission
2 - Brain neurotransmission
3 - Brain cellular structure
4 - Brain development
5 - Intracellular signalling
6 - Brain uncharacterized
7 - Retinal
8 - Neurohormonal
9 - Testis spermatogenesis
10 - Housekeeping transcription
11 - Testis uncharacterized
12 - Metabolic
13 - Testis sperm
14 - Low abundant uncharacterized
15 - Testis uncharacterized
16 - Aorta uncharacterized
17 - Cilium structure
18 - Low abundant uncharacterized
19 - Housekeeping mitochondrial
20 - Hormonal
21 - Low abundant uncharacterized
22 - Housekeeping transcription
23 - Cilium structure
24 - Low abundant uncharacterized
25 - Low abundant uncharacterized
26 - Low abundant uncharacterized
27 - Low abundant uncharacterized
28 - Housekeeping mitochondrial translation
29 - Male tissue bacterial defense
30 - Housekeeping structural
31 - Housekeeping uncharacterized
32 - Transport
33 - Lens
34 - Prostate uncharacterized
35 - Low abundant uncharacterized
36 - Receptors uncharacterized
37 - Olfactory bulb
38 - Lung and thyroid development
39 - Kidney transport
40 - Testis
41 - Low abundant uncharacterized
42 - Low abundant uncharacterized
43 - Breast uncharacterized
44 - Housekeeping
45 - Thymus uncharacterized
46 - Skeletal muscle contraction
47 - Spleen uncharacterized
48 - Low abundant uncharacterized
49 - Heart contraction
50 - Muscle contraction
51 - Liver and kidney
52 - Housekeeping
53 - Housekeeping mitochondrial
54 - Interferons
55 - Low abundant uncharacterized
56 - Low abundant uncharacterized
57 - Skin
58 - Immune cells
59 - Squamous epithelium
60 - Not detected
61 - Enzymes and secretion
62 - Squamous epithelium
63 - Small intestine
64 - Gastrointestinal
65 - Epithelium
66 - Housekeeping mRNA
67 - Gastrointestinal
68 - Housekeeping protein processing
69 - Housekeeping
70 - Housekeeping
71 - Housekeeping regulation
72 - Digestive and respiratory defense
73 - Housekeeping cell cycle
74 - Extracellular matrix
75 - Housekeeping
76 - Housekeeping regulation
77 - Housekeeping defense
78 - Lymphoid T cells
79 - Lymphoid myeloid
80 - Heart uncharacterized
81 - Vasculature and connective tissue
82 - Lymphoid B cell
83 - Not detected
84 - Epithelium transcription regulation
Tissue group
Any
Adipose tissue
Adrenal gland
Aorta
Bone marrow
Brain
Breast
Cartilage
Cervix
Choroid plexus
Cornea
Ductus deferens
Dura mater
Endometrium
Epididymis
Esophagus
Fallopian tube
Gallbladder
Heart
Kidney
Large intestine
Lens
Liver
Lung
Lymphoid tissue
Male glands
Mesothelial tissue
Mouth
Ovary
Penis
Pineal gland
Pituitary gland
Retina
Salivary gland
Skeletal muscle
Skin
Small intestine
Smooth muscle
Stomach
Synovial tissue
Testis
Thyroid gland
Upper respiratory system
Urinary bladder
Vagus nerve
Category
Tissue enriched
Group enriched
Tissue enhanced
Low tissue specificity
Not detected
Detected in all
Detected in many
Detected in some
Detected in single
Is highest expressed
Brain region
Any
Amygdala
Basal ganglia
Cerebellum
Cerebral cortex
Corpus callosum
Hippocampal formation
Hypothalamus
Midbrain
Olfactory region
Pituitary gland
Pons and medulla
Retina
Spinal cord
Thalamus
Category
Region enriched
Group enriched
Region enhanced
Low region specificity
Not detected
Detected in all
Detected in many
Detected in some
Detected in single
Is highest expressed
Column
Gene
Position
Tissue specific score
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THE PIG PROTEOME
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TISSUE SPECIFIC PROTEOME
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570 GENES FOUND
Gene
Gene
i
Gene name, if available.
Gene synonym (Human ortholog)
Ensembl gene id
Ensembl gene id (Proteincoding human ortholog)
Gene description
Uniprot accession (Human ortholog)
Chromosome
Chromosome position
Related human disease
RNA category pig
RNA pig tissue group specificity
RNA pig tissue group distribution
RNA pig tissue group specificity score
RNA pig tissue group specific NX
RNA pig brain regional specificity
RNA pig brain regional distribution
RNA pig brain regional specificity score
RNA pig brain regional specific pTPM
Annotation
UMAP cluster
Within tissue variation
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Select data columns:
Gene
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Gene
i
Gene name, if available.
Gene synonym (Human ortholog)
Ensembl gene id
Ensembl gene id (Proteincoding human ortholog)
Gene description
Uniprot accession (Human ortholog)
Chromosome
Chromosome position
Related human disease
RNA category pig
Expand
RNA pig tissue group specificity
RNA pig tissue group distribution
RNA pig tissue group specificity score
RNA pig tissue group specific NX
RNA pig brain regional specificity
RNA pig brain regional distribution
RNA pig brain regional specificity score
RNA pig brain regional specific pTPM
Annotation
Expand
UMAP cluster
Within tissue variation
Pig Tissue RNA
Expand
Abdominal adipose tissue [NX]
Adrenal gland [NX]
Amygdala [NX]
Aorta [NX]
Bone marrow [NX]
Breast [NX]
Bronchus [NX]
Bulbourethral gland [NX]
Caudate [NX]
Cecum [NX]
Cerebellum [NX]
Cervix [NX]
Choroid plexus [NX]
Cingulate cortex [NX]
Colon [NX]
Cornea [NX]
Corpus callosum [NX]
Dorsal hippocampus [NX]
Dorsal spinal cord [NX]
Ductus deferens [NX]
Duodenum [NX]
Dura mater [NX]
Ear cartilage [NX]
Endometrium 1 [NX]
Entorhinal cortex [NX]
Epididymis [NX]
Esophagus [NX]
Facial adipose tissue [NX]
Fallopian tube [NX]
Gallbladder [NX]
Heart atrium [NX]
Heart valve [NX]
Heart wall [NX]
Hypothalamus [NX]
Ileum [NX]
Insular cortex [NX]
Jejunum [NX]
Joint cartilage [NX]
Kidney (cortex) [NX]
Kidney (medulla) [NX]
Larynx [NX]
Lens [NX]
Lip [NX]
Liver [NX]
Lung [NX]
Lymph node [NX]
Medulla [NX]
Midbrain [NX]
Motor cortex [NX]
Nasopharynx epithelium [NX]
Occipital cortex [NX]
Olfactory bulb [NX]
Olfactory epithelium [NX]
Oral mucosa [NX]
Ovary [NX]
Penis [NX]
Periaqueductal gray [NX]
Peritoneum [NX]
Pineal gland [NX]
Pituitary gland [NX]
Pleura [NX]
Pons [NX]
Prefrontal cortex [NX]
Prostate [NX]
Putamen [NX]
Rectum [NX]
Retina [NX]
Retrosplenial cortex [NX]
Salivary gland [NX]
Seminal vesicle [NX]
Septum [NX]
Skeletal muscle [NX]
Skin (back) [NX]
Skin (groin) [NX]
Smooth muscle (intestine) [NX]
Somatosensory cortex [NX]
Spleen [NX]
Stomach (lower) [NX]
Stomach (upper) [NX]
Subcutaneous adipose tissue [NX]
Subiculum [NX]
Substantia nigra [NX]
Superior colliculi [NX]
Synovial tissue [NX]
Temporal cortex [NX]
Testis [NX]
Thalamus [NX]
Thymus [NX]
Thyroid gland [NX]
Tongue [NX]
Tonsil [NX]
Trachea [NX]
Urethral gland [NX]
Urinary bladder [NX]
Vagus nerve [NX]
Ventral hippocampus [NX]
Ventral pallidum [NX]
Ventral spinal cord [NX]
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Gene
i
Gene name, if available.
Ensembl
x
Human ortholog
x
Gene description
x
RNA pig tissue group specificity
x
RNA pig tissue group distribution
x
RNA pig tissue group specific NX
x
KIAA1324
ENSSSCG00000006836
ENSG00000116299
KIAA1324
Tissue enhanced
Detected in many
male glands:
100.4
pituitary gland:
104.7
salivary gland:
32.1
KIF21B
ENSSSCG00000021706
ENSG00000116852
Kinesin family member 21B
Tissue enhanced
Detected in many
brain:
29.8
stomach:
22.5
KIFC2
ENSSSCG00000026924
ENSG00000167702
Kinesin family member C2
Tissue enhanced
Detected in many
skin:
20.4
KIT
ENSSSCG00000008842
ENSG00000157404
Mast/stem cell growth factor receptor Kit precursor
Tissue enhanced
Detected in many
bone marrow:
36.7
KLF16
ENSSSCG00000024672
ENSG00000129911
Krueppel-like factor 16
Low tissue specificity
Detected in all
KLHL14
ENSSSCG00000003733
ENSG00000197705
Kelch like family member 14
Tissue enhanced
Detected in many
kidney:
16.0
male glands:
43.9
thyroid gland:
26.4
KLHL23
ENSSSCG00000015937
ENSG00000213160
Kelch like family member 23
Tissue enhanced
Detected in many
smooth muscle:
29.1
KLHL29
ENSSSCG00000008593
ENSG00000119771
Kelch like family member 29
Tissue enhanced
Detected in many
cartilage:
34.0
LAPTM5
ENSSSCG00000025034
ENSG00000162511
Lysosomal protein transmembrane 5
Tissue enhanced
Detected in many
lymphoid tissue:
82.6
LDLRAD4
ENSSSCG00000027417
ENSG00000168675
Low density lipoprotein receptor class A domain containing 4
Low tissue specificity
Detected in all
LEF1
ENSSSCG00000009148
ENSG00000138795
Lymphoid enhancer-binding factor 1
Tissue enriched
Detected in many
lymphoid tissue:
206.1
LGR4
ENSSSCG00000013335
ENSG00000205213
Leucine rich repeat containing G protein-coupled receptor 4
Tissue enhanced
Detected in many
stomach:
54.0
LMF1
ENSSSCG00000008009
ENSG00000103227
Lipase maturation factor 1
Low tissue specificity
Detected in all
LMO4
ENSSSCG00000006928
ENSG00000143013
LIM domain transcription factor LMO4
Tissue enhanced
Detected in all
heart:
94.7
LMTK2
ENSSSCG00000007599
ENSG00000164715
Lemur tyrosine kinase 2
Low tissue specificity
Detected in all
LPIN2
ENSSSCG00000038494
ENSG00000101577
Phosphatidate phosphatase LPIN2
Tissue enhanced
Detected in all
liver:
56.1
LRRC8A
ENSSSCG00000005664
ENSG00000136802
Leucine rich repeat containing 8 VRAC subunit A
Low tissue specificity
Detected in all
LRRK2
ENSSSCG00000000784
ENSG00000188906
Leucine-rich repeat serine/threonine-protein kinase 2
Tissue enhanced
Detected in all
lymphoid tissue:
45.3
LUZP1
ENSSSCG00000003532
ENSG00000169641
Leucine zipper protein 1
Low tissue specificity
Detected in all
LY75
ENSSSCG00000021956
ENSG00000054219,ENSG00000248672
Lymphocyte antigen 75 precursor
Tissue enhanced
Detected in many
lymphoid tissue:
56.9
LYPD6B
ENSSSCG00000015677
ENSG00000150556
LY6/PLAUR domain containing 6B
Tissue enhanced
Detected in many
male glands:
19.8
pituitary gland:
30.7
skin:
18.5
LZTR1
ENSSSCG00000010097
ENSG00000099949
Leucine zipper like transcription regulator 1
Low tissue specificity
Detected in all
MAGI1
ENSSSCG00000011497
ENSG00000151276
Membrane associated guanylate kinase, WW and PDZ domain containing 1
Low tissue specificity
Detected in all
MAL2
ENSSSCG00000006003
ENSG00000147676
Protein MAL2
Tissue enhanced
Detected in many
brain:
38.7
MAMLD1
ENSSSCG00000012741
ENSG00000013619
Mastermind like domain containing 1
Tissue enhanced
Detected in many
epididymis:
55.4
MAP3K10
ENSSSCG00000028036
ENSG00000130758
Mitogen-activated protein kinase kinase kinase 10
Tissue enhanced
Detected in all
brain:
32.3
MAP3K13
ENSSSCG00000011791
ENSG00000073803
Mitogen-activated protein kinase kinase kinase 13
Low tissue specificity
Detected in all
MAP4K2
ENSSSCG00000013020
ENSG00000168067
Mitogen-activated protein kinase kinase kinase kinase 2
Low tissue specificity
Detected in all
MAP4K3
ENSSSCG00000008475
ENSG00000011566
Mitogen-activated protein kinase kinase kinase kinase 3
Low tissue specificity
Detected in all
MAP7
ENSSSCG00000039049
ENSG00000135525
Microtubule associated protein 7
Tissue enhanced
Detected in many
pineal gland:
113.3
MARCKS
ENSSSCG00000037803
ENSG00000277443
Myristoylated alanine rich protein kinase C substrate
Tissue enhanced
Detected in all
lymphoid tissue:
134.8
MARK4
ENSSSCG00000022538
ENSG00000007047
Microtubule affinity regulating kinase 4
Low tissue specificity
Detected in all
MAST3
ENSSSCG00000013895
ENSG00000099308
Microtubule associated serine/threonine kinase 3
Tissue enhanced
Detected in all
brain:
42.6
MATK
ENSSSCG00000013494
ENSG00000007264
Megakaryocyte-associated tyrosine kinase
Tissue enhanced
Detected in many
lymphoid tissue:
14.4
pineal gland:
28.2
MCF2L
ENSSSCG00000021158
ENSG00000126217
MCF.2 cell line derived transforming sequence like
Tissue enhanced
Detected in many
male glands:
53.7
salivary gland:
43.8
stomach:
60.7
MED24
ENSSSCG00000029102
ENSG00000008838
Mediator complex subunit 24
Low tissue specificity
Detected in all
MED9
ENSSSCG00000018053
ENSG00000141026
Mediator complex subunit 9
Low tissue specificity
Detected in all
MEIS2
ENSSSCG00000004795
ENSG00000134138
Meis homeobox 2
Tissue enhanced
Detected in many
brain:
76.8
cervix:
58.1
MERTK
ENSSSCG00000008103
ENSG00000153208
MER proto-oncogene, tyrosine kinase
Low tissue specificity
Detected in all
METTL22
ENSSSCG00000007914
ENSG00000067365
Methyltransferase like 22
Low tissue specificity
Detected in all
MEX3A
ENSSSCG00000006497
ENSG00000254726
Mex-3 RNA binding family member A
Tissue enhanced
Detected in many
endometrium:
15.5
ovary:
9.9
MLLT3
ENSSSCG00000005166
ENSG00000171843
MLLT3, super elongation complex subunit
Low tissue specificity
Detected in many
MPND
ENSSSCG00000013507
ENSG00000008382
MPN domain containing
Low tissue specificity
Detected in all
MSL1
ENSSSCG00000017476
ENSG00000188895
Male specific lethal 1 homolog
Low tissue specificity
Detected in all
MTA3
ENSSSCG00000008464
ENSG00000057935
Metastasis associated 1 family member 3
Low tissue specificity
Detected in all
MTCL1
ENSSSCG00000003684
ENSG00000168502
Microtubule crosslinking factor 1
Low tissue specificity
Detected in all
MTFP1
ENSSSCG00000010007
ENSG00000242114
Mitochondrial fission process 1
Low tissue specificity
Detected in all
MTMR12
ENSSSCG00000031509
ENSG00000150712
Myotubularin related protein 12
Low tissue specificity
Detected in all
MTOR
ENSSSCG00000003413
ENSG00000198793
Mechanistic target of rapamycin kinase
Low tissue specificity
Detected in all
MYO6
ENSSSCG00000004478
ENSG00000196586
Unconventional myosin-VI
Low tissue specificity
Detected in all
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