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Human disease related genes
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UMAP gene cluster
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Keyword
Chromosome
1
2
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5
6
7
8
9
10
11
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MT
Unmapped
X
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External id
Variability
Variable
Not variable
Tissue
Any
Adipose tissue
Brain
Cartilage
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Lymphoid tissue
Male glands
Mesothelial tissue
Mouth
Skin
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Stomach 1
Upper respiratory system
Cluster
1 - Brain neurotransmission
2 - Brain neurotransmission
3 - Brain cellular structure
4 - Brain development
5 - Intracellular signalling
6 - Brain uncharacterized
7 - Retinal
8 - Neurohormonal
9 - Testis spermatogenesis
10 - Housekeeping transcription
11 - Testis uncharacterized
12 - Metabolic
13 - Testis sperm
14 - Low abundant uncharacterized
15 - Testis uncharacterized
16 - Aorta uncharacterized
17 - Cilium structure
18 - Low abundant uncharacterized
19 - Housekeeping mitochondrial
20 - Hormonal
21 - Low abundant uncharacterized
22 - Housekeeping transcription
23 - Cilium structure
24 - Low abundant uncharacterized
25 - Low abundant uncharacterized
26 - Low abundant uncharacterized
27 - Low abundant uncharacterized
28 - Housekeeping mitochondrial translation
29 - Male tissue bacterial defense
30 - Housekeeping structural
31 - Housekeeping uncharacterized
32 - Transport
33 - Lens
34 - Prostate uncharacterized
35 - Low abundant uncharacterized
36 - Receptors uncharacterized
37 - Olfactory bulb
38 - Lung and thyroid development
39 - Kidney transport
40 - Testis
41 - Low abundant uncharacterized
42 - Low abundant uncharacterized
43 - Breast uncharacterized
44 - Housekeeping
45 - Thymus uncharacterized
46 - Skeletal muscle contraction
47 - Spleen uncharacterized
48 - Low abundant uncharacterized
49 - Heart contraction
50 - Muscle contraction
51 - Liver and kidney
52 - Housekeeping
53 - Housekeeping mitochondrial
54 - Interferons
55 - Low abundant uncharacterized
56 - Low abundant uncharacterized
57 - Skin
58 - Immune cells
59 - Squamous epithelium
60 - Not detected
61 - Enzymes and secretion
62 - Squamous epithelium
63 - Small intestine
64 - Gastrointestinal
65 - Epithelium
66 - Housekeeping mRNA
67 - Gastrointestinal
68 - Housekeeping protein processing
69 - Housekeeping
70 - Housekeeping
71 - Housekeeping regulation
72 - Digestive and respiratory defense
73 - Housekeeping cell cycle
74 - Extracellular matrix
75 - Housekeeping
76 - Housekeeping regulation
77 - Housekeeping defense
78 - Lymphoid T cells
79 - Lymphoid myeloid
80 - Heart uncharacterized
81 - Vasculature and connective tissue
82 - Lymphoid B cell
83 - Not detected
84 - Epithelium transcription regulation
Tissue group
Any
Adipose tissue
Adrenal gland
Aorta
Bone marrow
Brain
Breast
Cartilage
Cervix
Choroid plexus
Cornea
Ductus deferens
Dura mater
Endometrium
Epididymis
Esophagus
Fallopian tube
Gallbladder
Heart
Kidney
Large intestine
Lens
Liver
Lung
Lymphoid tissue
Male glands
Mesothelial tissue
Mouth
Ovary
Penis
Pineal gland
Pituitary gland
Retina
Salivary gland
Skeletal muscle
Skin
Small intestine
Smooth muscle
Stomach
Synovial tissue
Testis
Thyroid gland
Upper respiratory system
Urinary bladder
Vagus nerve
Category
Tissue enriched
Group enriched
Tissue enhanced
Low tissue specificity
Not detected
Detected in all
Detected in many
Detected in some
Detected in single
Is highest expressed
Brain region
Any
Amygdala
Basal ganglia
Cerebellum
Cerebral cortex
Corpus callosum
Hippocampal formation
Hypothalamus
Midbrain
Olfactory region
Pituitary gland
Pons and medulla
Retina
Spinal cord
Thalamus
Category
Region enriched
Group enriched
Region enhanced
Low region specificity
Not detected
Detected in all
Detected in many
Detected in some
Detected in single
Is highest expressed
Column
Gene
Position
Tissue specific score
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THE PIG PROTEOME
THE PIG ATLAS
TISSUE SPECIFIC PROTEOME
UMAP GENE CLUSTERING
BIOMEDICAL RESEARCH
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THE PROJECT
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RELEASE HISTORY
826 GENES FOUND
Gene
Gene
i
Gene name, if available.
Gene synonym (Human ortholog)
Ensembl gene id
Ensembl gene id (Proteincoding human ortholog)
Gene description
Uniprot accession (Human ortholog)
Chromosome
Chromosome position
Related human disease
RNA category pig
RNA pig tissue group specificity
RNA pig tissue group distribution
RNA pig tissue group specificity score
RNA pig tissue group specific NX
RNA pig brain regional specificity
RNA pig brain regional distribution
RNA pig brain regional specificity score
RNA pig brain regional specific pTPM
Annotation
UMAP cluster
Within tissue variation
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1.
Select data columns:
Gene
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Gene
i
Gene name, if available.
Gene synonym (Human ortholog)
Ensembl gene id
Ensembl gene id (Proteincoding human ortholog)
Gene description
Uniprot accession (Human ortholog)
Chromosome
Chromosome position
Related human disease
RNA category pig
Expand
RNA pig tissue group specificity
RNA pig tissue group distribution
RNA pig tissue group specificity score
RNA pig tissue group specific NX
RNA pig brain regional specificity
RNA pig brain regional distribution
RNA pig brain regional specificity score
RNA pig brain regional specific pTPM
Annotation
Expand
UMAP cluster
Within tissue variation
Pig Tissue RNA
Expand
Abdominal adipose tissue [NX]
Adrenal gland [NX]
Amygdala [NX]
Aorta [NX]
Bone marrow [NX]
Breast [NX]
Bronchus [NX]
Bulbourethral gland [NX]
Caudate [NX]
Cecum [NX]
Cerebellum [NX]
Cervix [NX]
Choroid plexus [NX]
Cingulate cortex [NX]
Colon [NX]
Cornea [NX]
Corpus callosum [NX]
Dorsal hippocampus [NX]
Dorsal spinal cord [NX]
Ductus deferens [NX]
Duodenum [NX]
Dura mater [NX]
Ear cartilage [NX]
Endometrium 1 [NX]
Entorhinal cortex [NX]
Epididymis [NX]
Esophagus [NX]
Facial adipose tissue [NX]
Fallopian tube [NX]
Gallbladder [NX]
Heart atrium [NX]
Heart valve [NX]
Heart wall [NX]
Hypothalamus [NX]
Ileum [NX]
Insular cortex [NX]
Jejunum [NX]
Joint cartilage [NX]
Kidney (cortex) [NX]
Kidney (medulla) [NX]
Larynx [NX]
Lens [NX]
Lip [NX]
Liver [NX]
Lung [NX]
Lymph node [NX]
Medulla [NX]
Midbrain [NX]
Motor cortex [NX]
Nasopharynx epithelium [NX]
Occipital cortex [NX]
Olfactory bulb [NX]
Olfactory epithelium [NX]
Oral mucosa [NX]
Ovary [NX]
Penis [NX]
Periaqueductal gray [NX]
Peritoneum [NX]
Pineal gland [NX]
Pituitary gland [NX]
Pleura [NX]
Pons [NX]
Prefrontal cortex [NX]
Prostate [NX]
Putamen [NX]
Rectum [NX]
Retina [NX]
Retrosplenial cortex [NX]
Salivary gland [NX]
Seminal vesicle [NX]
Septum [NX]
Skeletal muscle [NX]
Skin (back) [NX]
Skin (groin) [NX]
Smooth muscle (intestine) [NX]
Somatosensory cortex [NX]
Spleen [NX]
Stomach (lower) [NX]
Stomach (upper) [NX]
Subcutaneous adipose tissue [NX]
Subiculum [NX]
Substantia nigra [NX]
Superior colliculi [NX]
Synovial tissue [NX]
Temporal cortex [NX]
Testis [NX]
Thalamus [NX]
Thymus [NX]
Thyroid gland [NX]
Tongue [NX]
Tonsil [NX]
Trachea [NX]
Urethral gland [NX]
Urinary bladder [NX]
Vagus nerve [NX]
Ventral hippocampus [NX]
Ventral pallidum [NX]
Ventral spinal cord [NX]
2.
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Gene
i
Gene name, if available.
Ensembl
x
Human ortholog
x
Gene description
x
RNA pig tissue group specificity
x
RNA pig tissue group distribution
x
RNA pig tissue group specific NX
x
LCAT
ENSSSCG00000028350
ENSG00000213398
Phosphatidylcholine-sterol acyltransferase precursor
Tissue enhanced
Detected in many
brain:
21.7
liver:
56.4
LDOC1
ENSSSCG00000034189
ENSG00000182195
LDOC1, regulator of NFKB signaling
Tissue enhanced
Detected in all
male glands:
90.8
LGI2
ENSSSCG00000028927
ENSG00000153012
Leucine rich repeat LGI family member 2
Tissue enhanced
Detected in many
adipose tissue:
8.8
brain:
29.9
mesothelial tissue:
12.9
LGI3
ENSSSCG00000033355
ENSG00000168481
Leucine rich repeat LGI family member 3
Group enriched
Detected in many
brain:
31.7
vagus nerve:
9.8
LHFPL3
ENSSSCG00000035554
ENSG00000187416
LHFPL tetraspan subfamily member 3
Tissue enhanced
Detected in many
brain:
19.5
pineal gland:
52.9
retina:
54.9
LIN7B
ENSSSCG00000003157
ENSG00000104863
Protein lin-7 homolog B
Tissue enhanced
Detected in all
brain:
26.5
lens:
21.6
LINGO4
ENSSSCG00000026259
ENSG00000213171
Leucine rich repeat and Ig domain containing 4
Tissue enriched
Detected in some
brain:
29.5
LMO1
ENSSSCG00000023057
ENSG00000166407
Rhombotin-1
Tissue enhanced
Detected in many
brain:
17.4
breast:
10.1
LPGAT1
ENSSSCG00000015603
ENSG00000123684
Lysophosphatidylglycerol acyltransferase 1
Low tissue specificity
Detected in all
LRCH2
ENSSSCG00000012595
ENSG00000130224
Leucine rich repeats and calponin homology domain containing 2
Low tissue specificity
Detected in many
LRRC49
ENSSSCG00000004976
ENSG00000137821
Leucine rich repeat containing 49
Tissue enhanced
Detected in some
brain:
29.9
pineal gland:
27.4
pituitary gland:
13.9
retina:
15.3
testis:
12.9
LRRC61
ENSSSCG00000040690
ENSG00000127399
Leucine rich repeat containing 61
Tissue enhanced
Detected in all
testis:
28.3
LRRC75B
ENSSSCG00000010057
ENSG00000178026
Leucine rich repeat containing 75B
Tissue enhanced
Detected in many
lens:
17.5
male glands:
13.8
LRRN1
ENSSSCG00000023806
ENSG00000175928
Leucine rich repeat neuronal 1
Group enriched
Detected in many
brain:
37.9
pineal gland:
27.7
LSAMP
ENSSSCG00000027941
ENSG00000185565
Limbic system-associated membrane protein precursor
Tissue enhanced
Detected in many
brain:
36.5
lens:
68.9
lymphoid tissue:
29.3
pineal gland:
33.4
LURAP1
ENSSSCG00000026991
ENSG00000171357
Leucine rich adaptor protein 1
Tissue enhanced
Detected in many
brain:
47.6
vagus nerve:
22.9
LYSMD1
ENSSSCG00000020965
ENSG00000163155
LysM and putative peptidoglycan-binding domain-containing protein 1
Low tissue specificity
Detected in all
MAGEF1
ENSSSCG00000011787
ENSG00000177383
MAGE family member F1
Low tissue specificity
Detected in all
MAGEL2
ENSSSCG00000004835
ENSG00000254585
MAGE family member L2
Tissue enhanced
Detected in many
brain:
19.3
pituitary gland:
9.7
MAGI2
ENSSSCG00000031780
ENSG00000187391
Membrane associated guanylate kinase, WW and PDZ domain containing 2
Tissue enhanced
Detected in many
brain:
31.7
lens:
39.6
MANEAL
ENSSSCG00000032960
ENSG00000185090
Mannosidase endo-alpha like
Tissue enhanced
Detected in many
brain:
19.1
lens:
30.3
MAP1A
ENSSSCG00000004705
ENSG00000166963
Microtubule associated protein 1A
Tissue enriched
Detected in many
brain:
71.4
MAP1B
ENSSSCG00000016974
ENSG00000131711
Microtubule associated protein 1B
Tissue enhanced
Detected in many
brain:
87.9
ovary:
44.6
MAP6
ENSSSCG00000014860
ENSG00000171533
Microtubule associated protein 6
Tissue enhanced
Detected in many
brain:
25.3
pituitary gland:
16.7
retina:
16.4
MAP6D1
ENSSSCG00000032328
ENSG00000180834
MAP6 domain containing 1
Tissue enriched
Detected in many
brain:
43.4
MAPK10
ENSSSCG00000009228
ENSG00000109339
Mitogen-activated protein kinase 10
Tissue enhanced
Detected in many
brain:
50.3
MAPK8IP1
ENSSSCG00000013269
ENSG00000121653
Mitogen-activated protein kinase 8 interacting protein 1
Tissue enriched
Detected in many
lens:
242.7
MAPRE2
ENSSSCG00000003738
ENSG00000166974
Microtubule associated protein RP/EB family member 2
Tissue enhanced
Detected in all
brain:
60.4
MAPRE3
ENSSSCG00000029185
ENSG00000084764
Microtubule associated protein RP/EB family member 3
Tissue enhanced
Detected in all
brain:
50.1
MARCH9
ENSSSCG00000033013
ENSG00000139266
Membrane associated ring-CH-type finger 9
Low tissue specificity
Detected in all
MBD5
ENSSSCG00000015667
ENSG00000204406
Methyl-CpG binding domain protein 5
Low tissue specificity
Detected in all
MBLAC2
ENSSSCG00000014152
ENSG00000176055
Metallo-beta-lactamase domain containing 2
Low tissue specificity
Detected in all
MBOAT2
ENSSSCG00000023539
ENSG00000143797
Membrane bound O-acyltransferase domain containing 2
Tissue enhanced
Detected in all
choroid plexus:
38.6
MCF2L2
ENSSSCG00000021749
ENSG00000053524
MCF.2 cell line derived transforming sequence-like 2
Tissue enhanced
Detected in many
pineal gland:
24.3
retina:
54.1
MDGA2
ENSSSCG00000005002
ENSG00000139915
MAM domain containing glycosylphosphatidylinositol anchor 2
Tissue enhanced
Detected in many
brain:
17.1
lens:
37.4
retina:
18.1
thyroid gland:
22.6
MEGF9
ENSSSCG00000005506
ENSG00000106780
Multiple EGF like domains 9
Group enriched
Detected in many
lens:
106.8
retina:
33.9
vagus nerve:
52.2
MESP1
ENSSSCG00000001847
ENSG00000166823
Mesoderm posterior bHLH transcription factor 1
Low tissue specificity
Detected in all
MICU3
ENSSSCG00000006981
ENSG00000155970
Mitochondrial calcium uptake family member 3
Tissue enhanced
Detected in all
brain:
41.3
MLC1
ENSSSCG00000000978
ENSG00000100427
Megalencephalic leukoencephalopathy with subcortical cysts 1
Tissue enriched
Detected in some
brain:
42.7
MMEL1
ENSSSCG00000003356
ENSG00000142606
Membrane metalloendopeptidase like 1
Tissue enriched
Detected in some
testis:
31.2
MOG
ENSSSCG00000001248
ENSG00000204655
Myelin-oligodendrocyte glycoprotein precursor
Tissue enriched
Detected in some
brain:
170.0
MORN4
ENSSSCG00000036954
ENSG00000171160
MORN repeat containing 4
Tissue enhanced
Detected in all
brain:
31.0
MPPED2
ENSSSCG00000013327
ENSG00000066382
Metallophosphoesterase domain containing 2
Tissue enhanced
Detected in many
kidney:
28.2
male glands:
33.9
MRO
ENSSSCG00000004521
ENSG00000134042
Protein maestro
Group enriched
Detected in some
ovary:
59.4
testis:
16.0
MSANTD3-TMEFF1
ENSSSCG00000005391
ENSG00000251349
MSANTD3-TMEFF1 readthrough
Tissue enhanced
Detected in many
brain:
44.5
MSANTD4
ENSSSCG00000026833
ENSG00000170903
Myb/SANT DNA binding domain containing 4 with coiled-coils
Low tissue specificity
Detected in all
MT3
ENSSSCG00000024305
ENSG00000087250
Metallothionein-3
Tissue enhanced
Detected in many
brain:
123.6
pineal gland:
25.4
pituitary gland:
40.4
MTHFD1L
ENSSSCG00000004092
ENSG00000120254
Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like
Tissue enhanced
Detected in many
epididymis:
39.7
lens:
35.0
MTURN
ENSSSCG00000037158
ENSG00000180354
Maturin
Tissue enhanced
Detected in all
brain:
55.6
epididymis:
50.3
MVB12B
ENSSSCG00000036926
ENSG00000196814
Multivesicular body subunit 12B
Tissue enhanced
Detected in all
lens:
78.6
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