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Human disease related genes
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UMAP gene cluster
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Keyword
Chromosome
1
2
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5
6
7
8
9
10
11
12
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MT
Unmapped
X
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External id
Variability
Variable
Not variable
Tissue
Any
Adipose tissue
Brain
Cartilage
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Lymphoid tissue
Male glands
Mesothelial tissue
Mouth
Skin
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Stomach 1
Upper respiratory system
Cluster
1 - Brain neurotransmission
2 - Brain neurotransmission
3 - Brain cellular structure
4 - Brain development
5 - Intracellular signalling
6 - Brain uncharacterized
7 - Retinal
8 - Neurohormonal
9 - Testis spermatogenesis
10 - Housekeeping transcription
11 - Testis uncharacterized
12 - Metabolic
13 - Testis sperm
14 - Low abundant uncharacterized
15 - Testis uncharacterized
16 - Aorta uncharacterized
17 - Cilium structure
18 - Low abundant uncharacterized
19 - Housekeeping mitochondrial
20 - Hormonal
21 - Low abundant uncharacterized
22 - Housekeeping transcription
23 - Cilium structure
24 - Low abundant uncharacterized
25 - Low abundant uncharacterized
26 - Low abundant uncharacterized
27 - Low abundant uncharacterized
28 - Housekeeping mitochondrial translation
29 - Male tissue bacterial defense
30 - Housekeeping structural
31 - Housekeeping uncharacterized
32 - Transport
33 - Lens
34 - Prostate uncharacterized
35 - Low abundant uncharacterized
36 - Receptors uncharacterized
37 - Olfactory bulb
38 - Lung and thyroid development
39 - Kidney transport
40 - Testis
41 - Low abundant uncharacterized
42 - Low abundant uncharacterized
43 - Breast uncharacterized
44 - Housekeeping
45 - Thymus uncharacterized
46 - Skeletal muscle contraction
47 - Spleen uncharacterized
48 - Low abundant uncharacterized
49 - Heart contraction
50 - Muscle contraction
51 - Liver and kidney
52 - Housekeeping
53 - Housekeeping mitochondrial
54 - Interferons
55 - Low abundant uncharacterized
56 - Low abundant uncharacterized
57 - Skin
58 - Immune cells
59 - Squamous epithelium
60 - Not detected
61 - Enzymes and secretion
62 - Squamous epithelium
63 - Small intestine
64 - Gastrointestinal
65 - Epithelium
66 - Housekeeping mRNA
67 - Gastrointestinal
68 - Housekeeping protein processing
69 - Housekeeping
70 - Housekeeping
71 - Housekeeping regulation
72 - Digestive and respiratory defense
73 - Housekeeping cell cycle
74 - Extracellular matrix
75 - Housekeeping
76 - Housekeeping regulation
77 - Housekeeping defense
78 - Lymphoid T cells
79 - Lymphoid myeloid
80 - Heart uncharacterized
81 - Vasculature and connective tissue
82 - Lymphoid B cell
83 - Not detected
84 - Epithelium transcription regulation
Tissue group
Any
Adipose tissue
Adrenal gland
Aorta
Bone marrow
Brain
Breast
Cartilage
Cervix
Choroid plexus
Cornea
Ductus deferens
Dura mater
Endometrium
Epididymis
Esophagus
Fallopian tube
Gallbladder
Heart
Kidney
Large intestine
Lens
Liver
Lung
Lymphoid tissue
Male glands
Mesothelial tissue
Mouth
Ovary
Penis
Pineal gland
Pituitary gland
Retina
Salivary gland
Skeletal muscle
Skin
Small intestine
Smooth muscle
Stomach
Synovial tissue
Testis
Thyroid gland
Upper respiratory system
Urinary bladder
Vagus nerve
Category
Tissue enriched
Group enriched
Tissue enhanced
Low tissue specificity
Not detected
Detected in all
Detected in many
Detected in some
Detected in single
Is highest expressed
Brain region
Any
Amygdala
Basal ganglia
Cerebellum
Cerebral cortex
Corpus callosum
Hippocampal formation
Hypothalamus
Midbrain
Olfactory region
Pituitary gland
Pons and medulla
Retina
Spinal cord
Thalamus
Category
Region enriched
Group enriched
Region enhanced
Low region specificity
Not detected
Detected in all
Detected in many
Detected in some
Detected in single
Is highest expressed
Column
Gene
Position
Tissue specific score
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THE PIG PROTEOME
THE PIG ATLAS
TISSUE SPECIFIC PROTEOME
UMAP GENE CLUSTERING
BIOMEDICAL RESEARCH
DICTIONARY
THE PROJECT
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916 GENES FOUND
Gene
Gene
i
Gene name, if available.
Gene synonym (Human ortholog)
Ensembl gene id
Ensembl gene id (Proteincoding human ortholog)
Gene description
Uniprot accession (Human ortholog)
Chromosome
Chromosome position
Related human disease
RNA category pig
RNA pig tissue group specificity
RNA pig tissue group distribution
RNA pig tissue group specificity score
RNA pig tissue group specific NX
RNA pig brain regional specificity
RNA pig brain regional distribution
RNA pig brain regional specificity score
RNA pig brain regional specific pTPM
Annotation
UMAP cluster
Within tissue variation
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1.
Select data columns:
Gene
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Gene
i
Gene name, if available.
Gene synonym (Human ortholog)
Ensembl gene id
Ensembl gene id (Proteincoding human ortholog)
Gene description
Uniprot accession (Human ortholog)
Chromosome
Chromosome position
Related human disease
RNA category pig
Expand
RNA pig tissue group specificity
RNA pig tissue group distribution
RNA pig tissue group specificity score
RNA pig tissue group specific NX
RNA pig brain regional specificity
RNA pig brain regional distribution
RNA pig brain regional specificity score
RNA pig brain regional specific pTPM
Annotation
Expand
UMAP cluster
Within tissue variation
Pig Tissue RNA
Expand
Abdominal adipose tissue [NX]
Adrenal gland [NX]
Amygdala [NX]
Aorta [NX]
Bone marrow [NX]
Breast [NX]
Bronchus [NX]
Bulbourethral gland [NX]
Caudate [NX]
Cecum [NX]
Cerebellum [NX]
Cervix [NX]
Choroid plexus [NX]
Cingulate cortex [NX]
Colon [NX]
Cornea [NX]
Corpus callosum [NX]
Dorsal hippocampus [NX]
Dorsal spinal cord [NX]
Ductus deferens [NX]
Duodenum [NX]
Dura mater [NX]
Ear cartilage [NX]
Endometrium 1 [NX]
Entorhinal cortex [NX]
Epididymis [NX]
Esophagus [NX]
Facial adipose tissue [NX]
Fallopian tube [NX]
Gallbladder [NX]
Heart atrium [NX]
Heart valve [NX]
Heart wall [NX]
Hypothalamus [NX]
Ileum [NX]
Insular cortex [NX]
Jejunum [NX]
Joint cartilage [NX]
Kidney (cortex) [NX]
Kidney (medulla) [NX]
Larynx [NX]
Lens [NX]
Lip [NX]
Liver [NX]
Lung [NX]
Lymph node [NX]
Medulla [NX]
Midbrain [NX]
Motor cortex [NX]
Nasopharynx epithelium [NX]
Occipital cortex [NX]
Olfactory bulb [NX]
Olfactory epithelium [NX]
Oral mucosa [NX]
Ovary [NX]
Penis [NX]
Periaqueductal gray [NX]
Peritoneum [NX]
Pineal gland [NX]
Pituitary gland [NX]
Pleura [NX]
Pons [NX]
Prefrontal cortex [NX]
Prostate [NX]
Putamen [NX]
Rectum [NX]
Retina [NX]
Retrosplenial cortex [NX]
Salivary gland [NX]
Seminal vesicle [NX]
Septum [NX]
Skeletal muscle [NX]
Skin (back) [NX]
Skin (groin) [NX]
Smooth muscle (intestine) [NX]
Somatosensory cortex [NX]
Spleen [NX]
Stomach (lower) [NX]
Stomach (upper) [NX]
Subcutaneous adipose tissue [NX]
Subiculum [NX]
Substantia nigra [NX]
Superior colliculi [NX]
Synovial tissue [NX]
Temporal cortex [NX]
Testis [NX]
Thalamus [NX]
Thymus [NX]
Thyroid gland [NX]
Tongue [NX]
Tonsil [NX]
Trachea [NX]
Urethral gland [NX]
Urinary bladder [NX]
Vagus nerve [NX]
Ventral hippocampus [NX]
Ventral pallidum [NX]
Ventral spinal cord [NX]
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Gene
i
Gene name, if available.
Ensembl
x
Human ortholog
x
Gene description
x
RNA pig tissue group specificity
x
RNA pig tissue group distribution
x
RNA pig tissue group specific NX
x
FOXI1
ENSSSCG00000017009
ENSG00000168269
Forkhead box I1
Tissue enriched
Detected in some
kidney:
61.2
FOXP2
ENSSSCG00000016639
ENSG00000128573
Forkhead box protein P2
Tissue enhanced
Detected in many
smooth muscle:
59.6
FRMD1
ENSSSCG00000004017
ENSG00000153303
FERM domain containing 1
Group enriched
Detected in many
gallbladder:
17.9
kidney:
49.5
testis:
53.6
FTCD
ENSSSCG00000027926
Formimidoyltransferase-cyclodeaminase
Group enriched
Detected in some
kidney:
44.3
liver:
100.5
FTL
ENSSSCG00000003153
ENSG00000087086
Ferritin light chain
Tissue enhanced
Detected in all
lens:
546.5
FXYD6
ENSSSCG00000015083
ENSG00000137726
FXYD domain containing ion transport regulator 6
Low tissue specificity
Detected in all
G6PC
ENSSSCG00000036449
ENSG00000131482
Glucose-6-phosphatase
Group enriched
Detected in many
kidney:
43.9
liver:
87.0
GABBR2
ENSSSCG00000027558
ENSG00000136928
Gamma-aminobutyric acid type B receptor subunit 2
Tissue enriched
Detected in some
brain:
44.5
GAL3ST1
ENSSSCG00000010009
ENSG00000128242
Galactosylceramide sulfotransferase
Tissue enhanced
Detected in many
brain:
27.1
kidney:
20.4
vagus nerve:
23.2
GAL3ST3
ENSSSCG00000028015
ENSG00000175229
Galactose-3-O-sulfotransferase 3
Tissue enhanced
Detected in many
brain:
13.3
epididymis:
15.4
mesothelial tissue:
16.8
GALNT14
ENSSSCG00000008524
ENSG00000158089
Polypeptide N-acetylgalactosaminyltransferase 14
Tissue enhanced
Detected in some
brain:
14.8
lens:
7.5
pituitary gland:
7.3
testis:
14.6
thyroid gland:
10.3
GALNT3
ENSSSCG00000015907
ENSG00000115339
Polypeptide N-acetylgalactosaminyltransferase 3
Tissue enhanced
Detected in many
male glands:
44.6
testis:
29.6
GALNT6
ENSSSCG00000026890
ENSG00000139629
Polypeptide N-acetylgalactosaminyltransferase 6
Tissue enhanced
Detected in many
esophagus:
50.7
male glands:
89.3
salivary gland:
53.5
GALR1
ENSSSCG00000036984
ENSG00000166573
Galanin receptor 1
Tissue enhanced
Detected in many
choroid plexus:
23.4
urinary bladder:
19.0
GAS2L2
ENSSSCG00000039395
ENSG00000270765
Growth arrest specific 2 like 2
Tissue enhanced
Detected in many
fallopian tube:
32.0
kidney:
15.2
upper respiratory system:
15.7
GATA3
ENSSSCG00000011125
ENSG00000107485
Trans-acting T-cell-specific transcription factor GATA-3
Tissue enhanced
Detected in many
kidney:
50.6
male glands:
129.9
skin:
97.0
urinary bladder:
53.3
GATM
ENSSSCG00000004672
ENSG00000171766
Glycine amidinotransferase, mitochondrial
Tissue enhanced
Detected in all
kidney:
41.3
liver:
75.6
male glands:
39.5
GBA3
ENSSSCG00000008754
Glucosylceramidase beta 3 (gene/pseudogene)
Tissue enhanced
Detected in many
kidney:
24.2
liver:
13.8
small intestine:
24.3
GDF7
ENSSSCG00000028931
ENSG00000143869
Growth differentiation factor 7
Tissue enhanced
Detected in some
cervix:
34.2
ductus deferens:
10.1
male glands:
25.3
upper respiratory system:
10.6
GDPD2
ENSSSCG00000012376
ENSG00000130055
Glycerophosphodiester phosphodiesterase domain containing 2
Tissue enhanced
Detected in many
choroid plexus:
25.2
skin:
29.3
GGACT
ENSSSCG00000009523
ENSG00000134864
Gamma-glutamylamine cyclotransferase
Tissue enhanced
Detected in all
kidney:
38.1
GGT5
ENSSSCG00000010055
ENSG00000099998
Gamma-glutamyltransferase 5
Low tissue specificity
Detected in all
GJA1
ENSSSCG00000004241
ENSG00000152661
Gap junction alpha-1 protein
Tissue enhanced
Detected in many
skin:
144.1
GJA4
ENSSSCG00000039983
ENSG00000187513
Gap junction alpha-4 protein
Tissue enhanced
Detected in many
aorta:
31.8
mesothelial tissue:
39.2
GJB1
ENSSSCG00000012394
ENSG00000169562
Gap junction protein beta 1
Tissue enhanced
Detected in many
epididymis:
101.6
liver:
97.0
male glands:
100.9
GLB1L
ENSSSCG00000016213
ENSG00000163521
Galactosidase beta 1 like
Tissue enhanced
Detected in all
kidney:
50.3
testis:
56.4
GLB1L2
ENSSSCG00000015258
ENSG00000149328
Galactosidase beta 1 like 2
Group enriched
Detected in many
epididymis:
120.8
thyroid gland:
84.9
GLIS1
ENSSSCG00000003846
ENSG00000174332
GLIS family zinc finger 1
Tissue enhanced
Detected in many
cartilage:
36.5
ductus deferens:
36.4
kidney:
25.7
GM2A
ENSSSCG00000017087
ENSG00000196743
GM2 ganglioside activator
Tissue enhanced
Detected in all
ovary:
56.9
GNG3
ENSSSCG00000032197
ENSG00000162188
G protein subunit gamma 3
Group enriched
Detected in some
brain:
62.3
pineal gland:
92.8
GP91-PHOX
ENSSSCG00000012229
ENSG00000165168
Cytochrome b-245 heavy chain precursor
Tissue enhanced
Detected in many
lung:
31.0
lymphoid tissue:
49.0
synovial tissue:
37.3
GPAT3
ENSSSCG00000009233
ENSG00000138678
Glycerol-3-phosphate acyltransferase 3
Tissue enhanced
Detected in many
kidney:
34.6
testis:
27.6
GPC3
ENSSSCG00000012680
ENSG00000147257
Glypican 3
Tissue enhanced
Detected in many
cornea:
55.3
liver:
32.8
GPC4
ENSSSCG00000012679
ENSG00000076716
Glypican 4
Tissue enhanced
Detected in many
ovary:
45.2
GPD1
ENSSSCG00000000214
ENSG00000167588
Glycerol-3-phosphate dehydrogenase
Tissue enhanced
Detected in all
adipose tissue:
55.9
skeletal muscle:
142.5
GPR68
ENSSSCG00000034114
ENSG00000119714
G protein-coupled receptor 68
Tissue enhanced
Detected in many
ovary:
18.4
GPRC5A
ENSSSCG00000029592
ENSG00000013588
G protein-coupled receptor class C group 5 member A
Tissue enhanced
Detected in many
cartilage:
35.0
large intestine:
51.4
lung:
52.1
synovial tissue:
47.7
GPRC5B
ENSSSCG00000007864
ENSG00000167191
G protein-coupled receptor class C group 5 member B
Tissue enhanced
Detected in all
brain:
75.1
lens:
84.2
ovary:
63.1
GPT2
ENSSSCG00000002847
ENSG00000166123
Glutamic--pyruvic transaminase 2
Tissue enhanced
Detected in many
brain:
43.4
kidney:
59.2
liver:
39.4
GPX3
ENSSSCG00000036438
ENSG00000211445
Glutathione peroxidase 3 precursor
Group enriched
Detected in many
kidney:
521.1
ovary:
496.9
GRAMD1B
ENSSSCG00000015144
ENSG00000023171
GRAM domain containing 1B
Tissue enhanced
Detected in many
adrenal gland:
111.6
kidney:
48.9
ovary:
43.4
GREM1
ENSSSCG00000033657
ENSG00000166923
Gremlin 1, DAN family BMP antagonist
Tissue enhanced
Detected in many
cartilage:
38.7
gallbladder:
38.9
kidney:
37.6
small intestine:
50.0
smooth muscle:
39.8
GSN
ENSSSCG00000037508
ENSG00000148180
Gelsolin
Tissue enhanced
Detected in all
cartilage:
266.2
heart:
223.1
penis:
327.1
GSTA1
ENSSSCG00000002623
ENSG00000182793,ENSG00000243955,ENSG00000244067
Tissue enhanced
Detected in many
liver:
176.9
male glands:
65.1
ovary:
103.3
small intestine:
67.1
GSTZ1
ENSSSCG00000002396
ENSG00000100577
Maleylacetoacetate isomerase
Tissue enhanced
Detected in all
liver:
86.1
HAAO
ENSSSCG00000038660
ENSG00000162882
3-hydroxyanthranilate 3,4-dioxygenase
Group enriched
Detected in many
kidney:
43.2
liver:
112.9
HAO1
ENSSSCG00000027439
ENSG00000101323
Hydroxyacid oxidase 1
Group enriched
Detected in some
kidney:
16.9
liver:
61.9
HAO2
ENSSSCG00000006720
ENSG00000116882
Hydroxyacid oxidase 2
Group enriched
Detected in all
kidney:
103.3
liver:
62.4
HDAC6
ENSSSCG00000025545
ENSG00000094631
Histone deacetylase 6
Tissue enriched
Detected in all
kidney:
96.2
HECW1
ENSSSCG00000036443
ENSG00000002746
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
Group enriched
Detected in some
brain:
17.4
kidney:
27.3
pineal gland:
14.3
retina:
9.4
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