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Human disease related genes
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Keyword
Chromosome
1
2
3
4
5
6
7
8
9
10
11
12
13
14
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MT
Unmapped
X
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External id
Variability
Variable
Not variable
Tissue
Any
Adipose tissue
Brain
Cartilage
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Lymphoid tissue
Male glands
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Mouth
Skin
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Stomach 1
Upper respiratory system
Cluster
1 - Brain neurotransmission
2 - Brain neurotransmission
3 - Brain cellular structure
4 - Brain development
5 - Intracellular signalling
6 - Brain uncharacterized
7 - Retinal
8 - Neurohormonal
9 - Testis spermatogenesis
10 - Housekeeping transcription
11 - Testis uncharacterized
12 - Metabolic
13 - Testis sperm
14 - Low abundant uncharacterized
15 - Testis uncharacterized
16 - Aorta uncharacterized
17 - Cilium structure
18 - Low abundant uncharacterized
19 - Housekeeping mitochondrial
20 - Hormonal
21 - Low abundant uncharacterized
22 - Housekeeping transcription
23 - Cilium structure
24 - Low abundant uncharacterized
25 - Low abundant uncharacterized
26 - Low abundant uncharacterized
27 - Low abundant uncharacterized
28 - Housekeeping mitochondrial translation
29 - Male tissue bacterial defense
30 - Housekeeping structural
31 - Housekeeping uncharacterized
32 - Transport
33 - Lens
34 - Prostate uncharacterized
35 - Low abundant uncharacterized
36 - Receptors uncharacterized
37 - Olfactory bulb
38 - Lung and thyroid development
39 - Kidney transport
40 - Testis
41 - Low abundant uncharacterized
42 - Low abundant uncharacterized
43 - Breast uncharacterized
44 - Housekeeping
45 - Thymus uncharacterized
46 - Skeletal muscle contraction
47 - Spleen uncharacterized
48 - Low abundant uncharacterized
49 - Heart contraction
50 - Muscle contraction
51 - Liver and kidney
52 - Housekeeping
53 - Housekeeping mitochondrial
54 - Interferons
55 - Low abundant uncharacterized
56 - Low abundant uncharacterized
57 - Skin
58 - Immune cells
59 - Squamous epithelium
60 - Not detected
61 - Enzymes and secretion
62 - Squamous epithelium
63 - Small intestine
64 - Gastrointestinal
65 - Epithelium
66 - Housekeeping mRNA
67 - Gastrointestinal
68 - Housekeeping protein processing
69 - Housekeeping
70 - Housekeeping
71 - Housekeeping regulation
72 - Digestive and respiratory defense
73 - Housekeeping cell cycle
74 - Extracellular matrix
75 - Housekeeping
76 - Housekeeping regulation
77 - Housekeeping defense
78 - Lymphoid T cells
79 - Lymphoid myeloid
80 - Heart uncharacterized
81 - Vasculature and connective tissue
82 - Lymphoid B cell
83 - Not detected
84 - Epithelium transcription regulation
Tissue group
Any
Adipose tissue
Adrenal gland
Aorta
Bone marrow
Brain
Breast
Cartilage
Cervix
Choroid plexus
Cornea
Ductus deferens
Dura mater
Endometrium
Epididymis
Esophagus
Fallopian tube
Gallbladder
Heart
Kidney
Large intestine
Lens
Liver
Lung
Lymphoid tissue
Male glands
Mesothelial tissue
Mouth
Ovary
Penis
Pineal gland
Pituitary gland
Retina
Salivary gland
Skeletal muscle
Skin
Small intestine
Smooth muscle
Stomach
Synovial tissue
Testis
Thyroid gland
Upper respiratory system
Urinary bladder
Vagus nerve
Category
Tissue enriched
Group enriched
Tissue enhanced
Low tissue specificity
Not detected
Detected in all
Detected in many
Detected in some
Detected in single
Is highest expressed
Brain region
Any
Amygdala
Basal ganglia
Cerebellum
Cerebral cortex
Corpus callosum
Hippocampal formation
Hypothalamus
Midbrain
Olfactory region
Pituitary gland
Pons and medulla
Retina
Spinal cord
Thalamus
Category
Region enriched
Group enriched
Region enhanced
Low region specificity
Not detected
Detected in all
Detected in many
Detected in some
Detected in single
Is highest expressed
Column
Gene
Position
Tissue specific score
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THE PIG PROTEOME
THE PIG ATLAS
TISSUE SPECIFIC PROTEOME
UMAP GENE CLUSTERING
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382 GENES FOUND
Gene
Gene
i
Gene name, if available.
Gene synonym (Human ortholog)
Ensembl gene id
Ensembl gene id (Proteincoding human ortholog)
Gene description
Uniprot accession (Human ortholog)
Chromosome
Chromosome position
Related human disease
RNA category pig
RNA pig tissue group specificity
RNA pig tissue group distribution
RNA pig tissue group specificity score
RNA pig tissue group specific NX
RNA pig brain regional specificity
RNA pig brain regional distribution
RNA pig brain regional specificity score
RNA pig brain regional specific pTPM
Annotation
UMAP cluster
Within tissue variation
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1.
Select data columns:
Gene
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Gene
i
Gene name, if available.
Gene synonym (Human ortholog)
Ensembl gene id
Ensembl gene id (Proteincoding human ortholog)
Gene description
Uniprot accession (Human ortholog)
Chromosome
Chromosome position
Related human disease
RNA category pig
Expand
RNA pig tissue group specificity
RNA pig tissue group distribution
RNA pig tissue group specificity score
RNA pig tissue group specific NX
RNA pig brain regional specificity
RNA pig brain regional distribution
RNA pig brain regional specificity score
RNA pig brain regional specific pTPM
Annotation
Expand
UMAP cluster
Within tissue variation
Pig Tissue RNA
Expand
Abdominal adipose tissue [NX]
Adrenal gland [NX]
Amygdala [NX]
Aorta [NX]
Bone marrow [NX]
Breast [NX]
Bronchus [NX]
Bulbourethral gland [NX]
Caudate [NX]
Cecum [NX]
Cerebellum [NX]
Cervix [NX]
Choroid plexus [NX]
Cingulate cortex [NX]
Colon [NX]
Cornea [NX]
Corpus callosum [NX]
Dorsal hippocampus [NX]
Dorsal spinal cord [NX]
Ductus deferens [NX]
Duodenum [NX]
Dura mater [NX]
Ear cartilage [NX]
Endometrium 1 [NX]
Entorhinal cortex [NX]
Epididymis [NX]
Esophagus [NX]
Facial adipose tissue [NX]
Fallopian tube [NX]
Gallbladder [NX]
Heart atrium [NX]
Heart valve [NX]
Heart wall [NX]
Hypothalamus [NX]
Ileum [NX]
Insular cortex [NX]
Jejunum [NX]
Joint cartilage [NX]
Kidney (cortex) [NX]
Kidney (medulla) [NX]
Larynx [NX]
Lens [NX]
Lip [NX]
Liver [NX]
Lung [NX]
Lymph node [NX]
Medulla [NX]
Midbrain [NX]
Motor cortex [NX]
Nasopharynx epithelium [NX]
Occipital cortex [NX]
Olfactory bulb [NX]
Olfactory epithelium [NX]
Oral mucosa [NX]
Ovary [NX]
Penis [NX]
Periaqueductal gray [NX]
Peritoneum [NX]
Pineal gland [NX]
Pituitary gland [NX]
Pleura [NX]
Pons [NX]
Prefrontal cortex [NX]
Prostate [NX]
Putamen [NX]
Rectum [NX]
Retina [NX]
Retrosplenial cortex [NX]
Salivary gland [NX]
Seminal vesicle [NX]
Septum [NX]
Skeletal muscle [NX]
Skin (back) [NX]
Skin (groin) [NX]
Smooth muscle (intestine) [NX]
Somatosensory cortex [NX]
Spleen [NX]
Stomach (lower) [NX]
Stomach (upper) [NX]
Subcutaneous adipose tissue [NX]
Subiculum [NX]
Substantia nigra [NX]
Superior colliculi [NX]
Synovial tissue [NX]
Temporal cortex [NX]
Testis [NX]
Thalamus [NX]
Thymus [NX]
Thyroid gland [NX]
Tongue [NX]
Tonsil [NX]
Trachea [NX]
Urethral gland [NX]
Urinary bladder [NX]
Vagus nerve [NX]
Ventral hippocampus [NX]
Ventral pallidum [NX]
Ventral spinal cord [NX]
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Gene
i
Gene name, if available.
Ensembl
x
Human ortholog
x
Gene description
x
RNA pig tissue group specificity
x
RNA pig tissue group distribution
x
RNA pig tissue group specific NX
x
IL7R
ENSSSCG00000016832
ENSG00000168685
Interleukin-7 receptor subunit alpha precursor
Tissue enhanced
Detected in many
lymphoid tissue:
39.3
small intestine:
13.2
stomach:
16.2
ILDR2
ENSSSCG00000035124
ENSG00000143195
Immunoglobulin like domain containing receptor 2
Tissue enhanced
Detected in many
liver:
19.0
IRX1
ENSSSCG00000034884
ENSG00000170549
Iroquois homeobox 1
Tissue enhanced
Detected in many
breast:
42.9
esophagus:
28.4
salivary gland:
50.8
skin:
34.9
IRX3
ENSSSCG00000002831
ENSG00000177508
Iroquois homeobox 3
Tissue enhanced
Detected in many
breast:
24.6
male glands:
63.3
IRX5
ENSSSCG00000032145
ENSG00000176842
Iroquois homeobox 5
Tissue enhanced
Detected in many
breast:
32.9
male glands:
51.4
ISL1
ENSSSCG00000016883
ENSG00000016082
ISL LIM homeobox 1
Tissue enhanced
Detected in many
male glands:
16.6
penis:
36.4
ISM1
ENSSSCG00000007073
ENSG00000101230
Isthmin 1
Tissue enhanced
Detected in many
cartilage:
84.7
ISYNA1
ENSSSCG00000040524
ENSG00000105655
Inositol-3-phosphate synthase 1
Tissue enhanced
Detected in many
choroid plexus:
135.7
testis:
64.6
ITGBL1
ENSSSCG00000009526
ENSG00000198542
Integrin subunit beta like 1
Tissue enhanced
Detected in many
aorta:
29.7
cornea:
42.0
dura mater:
31.8
vagus nerve:
32.9
ITIH3
ENSSSCG00000011451
ENSG00000162267
Inter-alpha-trypsin inhibitor heavy chain H3 precursor
Tissue enriched
Detected in many
liver:
105.3
KANK4
ENSSSCG00000003821
ENSG00000132854
KN motif and ankyrin repeat domains 4
Tissue enriched
Detected in many
vagus nerve:
84.4
KCNIP2
ENSSSCG00000010570
ENSG00000120049
Potassium voltage-gated channel interacting protein 2
Group enriched
Detected in many
brain:
34.9
heart:
89.5
KCNJ5
ENSSSCG00000021573
ENSG00000120457
G protein-activated inward rectifier potassium channel 4
Tissue enhanced
Detected in many
adrenal gland:
36.1
epididymis:
18.1
heart:
66.5
KCNK13
ENSSSCG00000002432
ENSG00000152315
Potassium channel subfamily K member 13
Tissue enhanced
Detected in some
adipose tissue:
8.6
kidney:
20.2
testis:
10.5
KCNMA1
ENSSSCG00000010325
ENSG00000156113
Calcium-activated potassium channel subunit alpha-1
Tissue enhanced
Detected in many
cervix:
87.5
pineal gland:
73.5
smooth muscle:
70.9
KERA
ENSSSCG00000000917
ENSG00000139330
Keratocan
Tissue enriched
Detected in many
cornea:
288.6
KIAA1324
ENSSSCG00000006836
ENSG00000116299
KIAA1324
Tissue enhanced
Detected in many
male glands:
100.4
pituitary gland:
104.7
salivary gland:
32.1
KLF5
ENSSSCG00000035101
ENSG00000102554
Krueppel-like factor 5
Tissue enhanced
Detected in many
large intestine:
80.4
stomach:
60.7
upper respiratory system:
64.6
KRT14
ENSSSCG00000017448
ENSG00000186847
Keratin 14
Tissue enhanced
Detected in many
large intestine:
131.5
mouth:
166.7
skin:
199.4
KRT7
ENSSSCG00000038966
ENSG00000135480
Keratin 7
Tissue enhanced
Detected in many
breast:
50.7
gallbladder:
38.2
salivary gland:
40.2
KRT8
ENSSSCG00000000252
ENSG00000170421
Keratin, type II cytoskeletal 8
Tissue enhanced
Detected in many
gallbladder:
64.3
large intestine:
167.1
stomach:
63.3
LAMC3
ENSSSCG00000005710
ENSG00000050555
Laminin subunit gamma 3
Tissue enhanced
Detected in many
penis:
26.8
LCN1
ENSSSCG00000035964
ENSG00000160349
Lipocalin-1 precursor
Group enriched
Detected in some
esophagus:
521.6
upper respiratory system:
1195.4
LEF1
ENSSSCG00000009148
ENSG00000138795
Lymphoid enhancer-binding factor 1
Tissue enriched
Detected in many
lymphoid tissue:
206.1
LGI2
ENSSSCG00000028927
ENSG00000153012
Leucine rich repeat LGI family member 2
Tissue enhanced
Detected in many
adipose tissue:
8.8
brain:
29.9
mesothelial tissue:
12.9
LGR5
ENSSSCG00000030511
ENSG00000139292
Leucine-rich repeat-containing G-protein coupled receptor 5 precursor
Tissue enhanced
Detected in many
skin:
34.4
LHX8
ENSSSCG00000003778
ENSG00000162624
LIM/homeobox protein Lhx8
Group enriched
Detected in some
adipose tissue:
18.4
brain:
12.0
esophagus:
10.8
lymphoid tissue:
14.8
mouth:
18.3
LMX1A
ENSSSCG00000006329
ENSG00000162761
LIM homeobox transcription factor 1 alpha
Group enriched
Detected in many
choroid plexus:
56.9
pineal gland:
31.0
LRP2
ENSSSCG00000040746
ENSG00000081479
LDL receptor related protein 2
Tissue enriched
Detected in many
kidney:
179.2
LRP4
ENSSSCG00000013248
ENSG00000134569
LDL receptor related protein 4
Tissue enhanced
Detected in many
skin:
40.7
small intestine:
32.8
LRRC4B
ENSSSCG00000029960
ENSG00000131409
Leucine rich repeat containing 4B
Group enriched
Detected in many
brain:
30.6
heart:
19.4
LTBP2
ENSSSCG00000002368
ENSG00000119681
Latent transforming growth factor beta binding protein 2
Tissue enhanced
Detected in many
mesothelial tissue:
67.7
LY86
ENSSSCG00000032355
ENSG00000112799
Lymphocyte antigen 86 precursor
Tissue enhanced
Detected in many
lymphoid tissue:
46.7
LYZ
ENSSSCG00000000492
ENSG00000090382
Lysozyme C-3 precursor
Tissue enhanced
Detected in many
large intestine:
87.6
small intestine:
117.4
stomach:
158.7
MAB21L1
ENSSSCG00000009351
ENSG00000180660
Mab-21 like 1
Tissue enhanced
Detected in many
lens:
45.0
retina:
44.9
MAOB
ENSSSCG00000023215
ENSG00000069535
Amine oxidase
Tissue enhanced
Detected in many
liver:
102.0
ovary:
41.3
MAPK15
ENSSSCG00000035933
ENSG00000181085
Mitogen-activated protein kinase 15
Tissue enhanced
Detected in many
fallopian tube:
59.5
lung:
50.4
upper respiratory system:
25.1
MATN2
ENSSSCG00000006082
ENSG00000132561
Matrilin 2
Tissue enhanced
Detected in many
adipose tissue:
49.5
mesothelial tissue:
53.4
MCU
ENSSSCG00000010290
ENSG00000156026
Mitochondrial calcium uniporter
Low tissue specificity
Detected in all
MEGF6
ENSSSCG00000024678
ENSG00000162591
Multiple EGF like domains 6
Tissue enhanced
Detected in many
mesothelial tissue:
34.2
MEIS1
ENSSSCG00000039161
ENSG00000143995
Meis homeobox 1
Tissue enhanced
Detected in many
fallopian tube:
45.9
MET
ENSSSCG00000024351
ENSG00000105976
Hepatocyte growth factor receptor
Tissue enhanced
Detected in many
thyroid gland:
33.5
MFAP3L
ENSSSCG00000009709
ENSG00000198948
Microfibril associated protein 3 like
Tissue enhanced
Detected in many
brain:
24.9
kidney:
38.9
skin:
23.6
MMP27
ENSSSCG00000014984
ENSG00000137675
Matrix metallopeptidase 27
Group enriched
Detected in some
adipose tissue:
14.1
cartilage:
7.3
mouth:
24.1
skin:
14.9
MPP6
ENSSSCG00000016717
ENSG00000105926
Membrane palmitoylated protein 6
Tissue enhanced
Detected in many
vagus nerve:
67.5
MST1R
ENSSSCG00000027992
ENSG00000164078
Macrophage stimulating 1 receptor
Tissue enhanced
Detected in many
skin:
31.4
stomach:
32.8
MYCL
ENSSSCG00000039761
ENSG00000116990
MYCL proto-oncogene, bHLH transcription factor
Tissue enhanced
Detected in many
stomach:
21.9
upper respiratory system:
27.0
urinary bladder:
33.8
MYO5B
ENSSSCG00000004511
ENSG00000167306
Myosin VB
Tissue enhanced
Detected in many
lens:
59.4
MYRF
ENSSSCG00000013078
ENSG00000124920
Myelin regulatory factor
Group enriched
Detected in many
adipose tissue:
28.3
brain:
62.5
gallbladder:
23.3
mesothelial tissue:
37.1
stomach:
55.6
na
ENSSSCG00000000759
Tissue enriched
Detected in many
lens:
87.5
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