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Human disease related genes
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UMAP gene cluster
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Keyword
Chromosome
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
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18
MT
Unmapped
X
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External id
Variability
Variable
Not variable
Tissue
Any
Adipose tissue
Brain
Cartilage
Heart
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Lymphoid tissue
Male glands
Mesothelial tissue
Mouth
Skin
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Stomach 1
Upper respiratory system
Cluster
1 - Brain neurotransmission
2 - Brain neurotransmission
3 - Brain cellular structure
4 - Brain development
5 - Intracellular signalling
6 - Brain uncharacterized
7 - Retinal
8 - Neurohormonal
9 - Testis spermatogenesis
10 - Housekeeping transcription
11 - Testis uncharacterized
12 - Metabolic
13 - Testis sperm
14 - Low abundant uncharacterized
15 - Testis uncharacterized
16 - Aorta uncharacterized
17 - Cilium structure
18 - Low abundant uncharacterized
19 - Housekeeping mitochondrial
20 - Hormonal
21 - Low abundant uncharacterized
22 - Housekeeping transcription
23 - Cilium structure
24 - Low abundant uncharacterized
25 - Low abundant uncharacterized
26 - Low abundant uncharacterized
27 - Low abundant uncharacterized
28 - Housekeeping mitochondrial translation
29 - Male tissue bacterial defense
30 - Housekeeping structural
31 - Housekeeping uncharacterized
32 - Transport
33 - Lens
34 - Prostate uncharacterized
35 - Low abundant uncharacterized
36 - Receptors uncharacterized
37 - Olfactory bulb
38 - Lung and thyroid development
39 - Kidney transport
40 - Testis
41 - Low abundant uncharacterized
42 - Low abundant uncharacterized
43 - Breast uncharacterized
44 - Housekeeping
45 - Thymus uncharacterized
46 - Skeletal muscle contraction
47 - Spleen uncharacterized
48 - Low abundant uncharacterized
49 - Heart contraction
50 - Muscle contraction
51 - Liver and kidney
52 - Housekeeping
53 - Housekeeping mitochondrial
54 - Interferons
55 - Low abundant uncharacterized
56 - Low abundant uncharacterized
57 - Skin
58 - Immune cells
59 - Squamous epithelium
60 - Not detected
61 - Enzymes and secretion
62 - Squamous epithelium
63 - Small intestine
64 - Gastrointestinal
65 - Epithelium
66 - Housekeeping mRNA
67 - Gastrointestinal
68 - Housekeeping protein processing
69 - Housekeeping
70 - Housekeeping
71 - Housekeeping regulation
72 - Digestive and respiratory defense
73 - Housekeeping cell cycle
74 - Extracellular matrix
75 - Housekeeping
76 - Housekeeping regulation
77 - Housekeeping defense
78 - Lymphoid T cells
79 - Lymphoid myeloid
80 - Heart uncharacterized
81 - Vasculature and connective tissue
82 - Lymphoid B cell
83 - Not detected
84 - Epithelium transcription regulation
Tissue group
Any
Adipose tissue
Adrenal gland
Aorta
Bone marrow
Brain
Breast
Cartilage
Cervix
Choroid plexus
Cornea
Ductus deferens
Dura mater
Endometrium
Epididymis
Esophagus
Fallopian tube
Gallbladder
Heart
Kidney
Large intestine
Lens
Liver
Lung
Lymphoid tissue
Male glands
Mesothelial tissue
Mouth
Ovary
Penis
Pineal gland
Pituitary gland
Retina
Salivary gland
Skeletal muscle
Skin
Small intestine
Smooth muscle
Stomach
Synovial tissue
Testis
Thyroid gland
Upper respiratory system
Urinary bladder
Vagus nerve
Category
Tissue enriched
Group enriched
Tissue enhanced
Low tissue specificity
Not detected
Detected in all
Detected in many
Detected in some
Detected in single
Is highest expressed
Brain region
Any
Amygdala
Basal ganglia
Cerebellum
Cerebral cortex
Corpus callosum
Hippocampal formation
Hypothalamus
Midbrain
Olfactory region
Pituitary gland
Pons and medulla
Retina
Spinal cord
Thalamus
Category
Region enriched
Group enriched
Region enhanced
Low region specificity
Not detected
Detected in all
Detected in many
Detected in some
Detected in single
Is highest expressed
Column
Gene
Position
Tissue specific score
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THE PIG PROTEOME
THE PIG ATLAS
TISSUE SPECIFIC PROTEOME
UMAP GENE CLUSTERING
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3143 GENES FOUND
Gene
Gene
i
Gene name, if available.
Gene synonym (Human ortholog)
Ensembl gene id
Ensembl gene id (Proteincoding human ortholog)
Gene description
Uniprot accession (Human ortholog)
Chromosome
Chromosome position
Related human disease
RNA category pig
RNA pig tissue group specificity
RNA pig tissue group distribution
RNA pig tissue group specificity score
RNA pig tissue group specific NX
RNA pig brain regional specificity
RNA pig brain regional distribution
RNA pig brain regional specificity score
RNA pig brain regional specific pTPM
Annotation
UMAP cluster
Within tissue variation
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1.
Select data columns:
Gene
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Gene
i
Gene name, if available.
Gene synonym (Human ortholog)
Ensembl gene id
Ensembl gene id (Proteincoding human ortholog)
Gene description
Uniprot accession (Human ortholog)
Chromosome
Chromosome position
Related human disease
RNA category pig
Expand
RNA pig tissue group specificity
RNA pig tissue group distribution
RNA pig tissue group specificity score
RNA pig tissue group specific NX
RNA pig brain regional specificity
RNA pig brain regional distribution
RNA pig brain regional specificity score
RNA pig brain regional specific pTPM
Annotation
Expand
UMAP cluster
Within tissue variation
Pig Tissue RNA
Expand
Abdominal adipose tissue [NX]
Adrenal gland [NX]
Amygdala [NX]
Aorta [NX]
Bone marrow [NX]
Breast [NX]
Bronchus [NX]
Bulbourethral gland [NX]
Caudate [NX]
Cecum [NX]
Cerebellum [NX]
Cervix [NX]
Choroid plexus [NX]
Cingulate cortex [NX]
Colon [NX]
Cornea [NX]
Corpus callosum [NX]
Dorsal hippocampus [NX]
Dorsal spinal cord [NX]
Ductus deferens [NX]
Duodenum [NX]
Dura mater [NX]
Ear cartilage [NX]
Endometrium 1 [NX]
Entorhinal cortex [NX]
Epididymis [NX]
Esophagus [NX]
Facial adipose tissue [NX]
Fallopian tube [NX]
Gallbladder [NX]
Heart atrium [NX]
Heart valve [NX]
Heart wall [NX]
Hypothalamus [NX]
Ileum [NX]
Insular cortex [NX]
Jejunum [NX]
Joint cartilage [NX]
Kidney (cortex) [NX]
Kidney (medulla) [NX]
Larynx [NX]
Lens [NX]
Lip [NX]
Liver [NX]
Lung [NX]
Lymph node [NX]
Medulla [NX]
Midbrain [NX]
Motor cortex [NX]
Nasopharynx epithelium [NX]
Occipital cortex [NX]
Olfactory bulb [NX]
Olfactory epithelium [NX]
Oral mucosa [NX]
Ovary [NX]
Penis [NX]
Periaqueductal gray [NX]
Peritoneum [NX]
Pineal gland [NX]
Pituitary gland [NX]
Pleura [NX]
Pons [NX]
Prefrontal cortex [NX]
Prostate [NX]
Putamen [NX]
Rectum [NX]
Retina [NX]
Retrosplenial cortex [NX]
Salivary gland [NX]
Seminal vesicle [NX]
Septum [NX]
Skeletal muscle [NX]
Skin (back) [NX]
Skin (groin) [NX]
Smooth muscle (intestine) [NX]
Somatosensory cortex [NX]
Spleen [NX]
Stomach (lower) [NX]
Stomach (upper) [NX]
Subcutaneous adipose tissue [NX]
Subiculum [NX]
Substantia nigra [NX]
Superior colliculi [NX]
Synovial tissue [NX]
Temporal cortex [NX]
Testis [NX]
Thalamus [NX]
Thymus [NX]
Thyroid gland [NX]
Tongue [NX]
Tonsil [NX]
Trachea [NX]
Urethral gland [NX]
Urinary bladder [NX]
Vagus nerve [NX]
Ventral hippocampus [NX]
Ventral pallidum [NX]
Ventral spinal cord [NX]
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Gene
i
Gene name, if available.
Ensembl
x
Human ortholog
x
Gene description
x
RNA pig tissue group specificity
x
RNA pig tissue group distribution
x
RNA pig tissue group specific NX
x
SHANK3
ENSSSCG00000031925
ENSG00000251322
SH3 and multiple ankyrin repeat domains 3
Low tissue specificity
Detected in all
SHC3
ENSSSCG00000039841
ENSG00000148082
SHC adaptor protein 3
Tissue enhanced
Detected in many
brain:
28.0
SHE
ENSSSCG00000006547
ENSG00000169291
Src homology 2 domain containing E
Low tissue specificity
Detected in many
SHISA2
ENSSSCG00000030113
ENSG00000180730
Shisa family member 2
Tissue enhanced
Detected in many
cartilage:
90.7
male glands:
23.3
skeletal muscle:
26.0
SHISA3
ENSSSCG00000040147
ENSG00000178343
Shisa family member 3
Tissue enhanced
Detected in many
cartilage:
17.0
vagus nerve:
61.0
SHISA4
ENSSSCG00000031981
ENSG00000198892
Shisa family member 4
Tissue enhanced
Detected in many
brain:
43.2
skeletal muscle:
124.2
SHISA8
ENSSSCG00000035755
ENSG00000234965
Shisa family member 8
Tissue enriched
Detected in many
vagus nerve:
85.6
SHISA9
ENSSSCG00000032878
ENSG00000237515
Shisa family member 9
Tissue enriched
Detected in some
brain:
51.9
SHROOM3
ENSSSCG00000008984
ENSG00000138771
Shroom family member 3
Tissue enhanced
Detected in many
ductus deferens:
63.6
salivary gland:
51.6
stomach:
71.7
SHROOM4
ENSSSCG00000012309
ENSG00000158352
Shroom family member 4
Low tissue specificity
Detected in many
SIM2
ENSSSCG00000027179
ENSG00000159263
Single-minded family bHLH transcription factor 2
Tissue enhanced
Detected in some
esophagus:
46.7
male glands:
42.5
stomach:
44.6
SIPA1L2
ENSSSCG00000010169
ENSG00000116991
Signal induced proliferation associated 1 like 2
Low tissue specificity
Detected in many
SIRPB2
ENSSSCG00000007185
ENSG00000196209
Signal regulatory protein beta 2
Tissue enhanced
Detected in all
lymphoid tissue:
24.2
SIT1
ENSSSCG00000005312
ENSG00000137078
Signaling threshold regulating transmembrane adaptor 1
Tissue enriched
Detected in some
lymphoid tissue:
64.0
SIX1
ENSSSCG00000005087
ENSG00000126778
Homeobox protein SIX1
Tissue enhanced
Detected in many
pituitary gland:
39.5
salivary gland:
31.6
skeletal muscle:
47.3
SIX5
ENSSSCG00000035791
ENSG00000177045
SIX homeobox 5
Low tissue specificity
Detected in many
SKAP2
ENSSSCG00000016708
ENSG00000005020
Src kinase associated phosphoprotein 2
Low tissue specificity
Detected in many
SKP2
ENSSSCG00000016835
ENSG00000145604
S-phase kinase-associated protein 2
Tissue enhanced
Detected in all
heart:
40.4
SLA
ENSSSCG00000005949
ENSG00000155926
Src like adaptor
Group enriched
Detected in all
lymphoid tissue:
39.2
thyroid gland:
112.2
SLA-5
ENSSSCG00000030767
MHC class I antigen 5 precursor
Low tissue specificity
Detected in many
SLA-DMA
ENSSSCG00000001470
ENSG00000204257
SLA-DM alpha chain precursor
Tissue enhanced
Detected in many
lymphoid tissue:
51.5
SLA-DMB
ENSSSCG00000001469
ENSG00000242574
MHC class II, DM beta precursor
Low tissue specificity
Detected in many
SLA-DQB1
ENSSSCG00000001457
ENSG00000179344,ENSG00000232629
SLA class II histocompatibility antigen, DQ haplotype C beta chain precursor
Tissue enhanced
Detected in many
lymphoid tissue:
129.0
SLAMF1
ENSSSCG00000006380
ENSG00000117090
Signaling lymphocytic activation molecule precursor
Tissue enriched
Detected in all
lymphoid tissue:
49.1
SLC10A6
ENSSSCG00000028952
ENSG00000145283
Solute carrier family 10 member 6
Tissue enhanced
Detected in many
mouth:
27.1
skin:
30.3
SLC11A1
ENSSSCG00000039798
ENSG00000018280
Natural resistance-associated macrophage protein 1
Tissue enriched
Detected in some
lymphoid tissue:
65.1
SLC12A2
ENSSSCG00000014255
ENSG00000064651
Solute carrier family 12 member 2
Tissue enriched
Detected in many
male glands:
217.5
SLC12A7
ENSSSCG00000034302
ENSG00000113504
Solute carrier family 12 member 7
Tissue enhanced
Detected in many
heart:
47.8
SLC15A2
ENSSSCG00000030305
ENSG00000163406
Solute carrier family 15 member 2
Tissue enhanced
Detected in many
lymphoid tissue:
37.7
SLC15A3
ENSSSCG00000013114
ENSG00000110446
Solute carrier family 15 member 3
Tissue enhanced
Detected in many
lymphoid tissue:
33.7
synovial tissue:
44.0
SLC16A1
ENSSSCG00000006771
ENSG00000155380
Monocarboxylate transporter 1
Tissue enhanced
Detected in many
large intestine:
76.4
SLC16A6
ENSSSCG00000017262
ENSG00000108932
Solute carrier family 16 member 6
Tissue enriched
Detected in many
choroid plexus:
84.7
SLC17A9
ENSSSCG00000040931
ENSG00000101194
Solute carrier family 17 member 9
Tissue enhanced
Detected in many
male glands:
40.3
stomach:
33.0
SLC18A1
ENSSSCG00000009601
ENSG00000036565
Solute carrier family 18 member A1
Tissue enhanced
Detected in many
adrenal gland:
26.0
lymphoid tissue:
12.0
SLC1A2
ENSSSCG00000013296
ENSG00000110436
Solute carrier family 1 member 2
Tissue enriched
Detected in some
brain:
89.6
SLC1A5
ENSSSCG00000003105
ENSG00000105281
Solute carrier family 1 member 5
Tissue enhanced
Detected in many
male glands:
70.1
SLC23A1
ENSSSCG00000026423
ENSG00000170482
Solute carrier family 23 member 1
Tissue enhanced
Detected in many
kidney:
50.6
male glands:
31.0
SLC24A3
ENSSSCG00000007100
ENSG00000185052
Solute carrier family 24 member 3
Tissue enhanced
Detected in many
brain:
52.7
SLC24A5
ENSSSCG00000004662
ENSG00000188467
Solute carrier family 24 member 5
Tissue enhanced
Detected in many
choroid plexus:
18.2
SLC27A1
ENSSSCG00000013879
ENSG00000130304
Long-chain fatty acid transport protein 1 precursor
Tissue enhanced
Detected in all
male glands:
48.1
SLC27A6
ENSSSCG00000014257
ENSG00000113396
Solute carrier family 27 member 6
Tissue enhanced
Detected in many
choroid plexus:
22.6
kidney:
34.9
SLC29A4
ENSSSCG00000027768
ENSG00000164638
Solute carrier family 29 member 4
Tissue enhanced
Detected in many
adrenal gland:
17.6
brain:
17.6
SLC2A6
ENSSSCG00000024166
ENSG00000160326
Solute carrier family 2 member 6
Tissue enhanced
Detected in many
brain:
17.6
lymphoid tissue:
13.1
stomach:
18.4
SLC31A2
ENSSSCG00000023714
ENSG00000136867
Probable low affinity copper uptake protein 2
Tissue enhanced
Detected in many
esophagus:
26.6
salivary gland:
89.5
upper respiratory system:
21.7
SLC35G2
ENSSSCG00000021508
ENSG00000168917
Solute carrier family 35 member G2
Tissue enhanced
Detected in many
brain:
26.4
pineal gland:
14.9
pituitary gland:
19.5
SLC37A2
ENSSSCG00000022536
ENSG00000134955
Solute carrier family 37 member 2
Tissue enhanced
Detected in all
choroid plexus:
58.4
SLC37A3
ENSSSCG00000032266
ENSG00000157800
Sugar phosphate exchanger 3
Tissue enhanced
Detected in all
lymphoid tissue:
43.2
SLC39A8
ENSSSCG00000009169
ENSG00000138821
Solute carrier family 39 member 8
Tissue enhanced
Detected in many
male glands:
64.5
mesothelial tissue:
55.2
upper respiratory system:
35.1
SLC40A1
ENSSSCG00000027157
ENSG00000138449
Solute carrier family 40 member 1
Tissue enhanced
Detected in many
bone marrow:
62.4
liver:
70.2
lymphoid tissue:
58.0
SLC41A2
ENSSSCG00000000838
ENSG00000136052
Solute carrier family 41 member 2
Tissue enhanced
Detected in all
male glands:
41.9
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