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Human disease related genes
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UMAP gene cluster
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Subclass
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Keyword
Chromosome
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
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18
MT
Unmapped
X
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External id
Variability
Variable
Not variable
Tissue
Any
Adipose tissue
Brain
Cartilage
Heart
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Large intestine
Lymphoid tissue
Male glands
Mesothelial tissue
Mouth
Skin
Small intestine
Stomach 1
Upper respiratory system
Cluster
1 - Brain neurotransmission
2 - Brain neurotransmission
3 - Brain cellular structure
4 - Brain development
5 - Intracellular signalling
6 - Brain uncharacterized
7 - Retinal
8 - Neurohormonal
9 - Testis spermatogenesis
10 - Housekeeping transcription
11 - Testis uncharacterized
12 - Metabolic
13 - Testis sperm
14 - Low abundant uncharacterized
15 - Testis uncharacterized
16 - Aorta uncharacterized
17 - Cilium structure
18 - Low abundant uncharacterized
19 - Housekeeping mitochondrial
20 - Hormonal
21 - Low abundant uncharacterized
22 - Housekeeping transcription
23 - Cilium structure
24 - Low abundant uncharacterized
25 - Low abundant uncharacterized
26 - Low abundant uncharacterized
27 - Low abundant uncharacterized
28 - Housekeeping mitochondrial translation
29 - Male tissue bacterial defense
30 - Housekeeping structural
31 - Housekeeping uncharacterized
32 - Transport
33 - Lens
34 - Prostate uncharacterized
35 - Low abundant uncharacterized
36 - Receptors uncharacterized
37 - Olfactory bulb
38 - Lung and thyroid development
39 - Kidney transport
40 - Testis
41 - Low abundant uncharacterized
42 - Low abundant uncharacterized
43 - Breast uncharacterized
44 - Housekeeping
45 - Thymus uncharacterized
46 - Skeletal muscle contraction
47 - Spleen uncharacterized
48 - Low abundant uncharacterized
49 - Heart contraction
50 - Muscle contraction
51 - Liver and kidney
52 - Housekeeping
53 - Housekeeping mitochondrial
54 - Interferons
55 - Low abundant uncharacterized
56 - Low abundant uncharacterized
57 - Skin
58 - Immune cells
59 - Squamous epithelium
60 - Not detected
61 - Enzymes and secretion
62 - Squamous epithelium
63 - Small intestine
64 - Gastrointestinal
65 - Epithelium
66 - Housekeeping mRNA
67 - Gastrointestinal
68 - Housekeeping protein processing
69 - Housekeeping
70 - Housekeeping
71 - Housekeeping regulation
72 - Digestive and respiratory defense
73 - Housekeeping cell cycle
74 - Extracellular matrix
75 - Housekeeping
76 - Housekeeping regulation
77 - Housekeeping defense
78 - Lymphoid T cells
79 - Lymphoid myeloid
80 - Heart uncharacterized
81 - Vasculature and connective tissue
82 - Lymphoid B cell
83 - Not detected
84 - Epithelium transcription regulation
Tissue group
Any
Adipose tissue
Adrenal gland
Aorta
Bone marrow
Brain
Breast
Cartilage
Cervix
Choroid plexus
Cornea
Ductus deferens
Dura mater
Endometrium
Epididymis
Esophagus
Fallopian tube
Gallbladder
Heart
Kidney
Large intestine
Lens
Liver
Lung
Lymphoid tissue
Male glands
Mesothelial tissue
Mouth
Ovary
Penis
Pineal gland
Pituitary gland
Retina
Salivary gland
Skeletal muscle
Skin
Small intestine
Smooth muscle
Stomach
Synovial tissue
Testis
Thyroid gland
Upper respiratory system
Urinary bladder
Vagus nerve
Category
Tissue enriched
Group enriched
Tissue enhanced
Low tissue specificity
Not detected
Detected in all
Detected in many
Detected in some
Detected in single
Is highest expressed
Brain region
Any
Amygdala
Basal ganglia
Cerebellum
Cerebral cortex
Corpus callosum
Hippocampal formation
Hypothalamus
Midbrain
Olfactory region
Pituitary gland
Pons and medulla
Retina
Spinal cord
Thalamus
Category
Region enriched
Group enriched
Region enhanced
Low region specificity
Not detected
Detected in all
Detected in many
Detected in some
Detected in single
Is highest expressed
Column
Gene
Position
Tissue specific score
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THE PIG PROTEOME
THE PIG ATLAS
TISSUE SPECIFIC PROTEOME
UMAP GENE CLUSTERING
BIOMEDICAL RESEARCH
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THE PROJECT
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1362 GENES FOUND
Gene
Gene
i
Gene name, if available.
Gene synonym (Human ortholog)
Ensembl gene id
Ensembl gene id (Proteincoding human ortholog)
Gene description
Uniprot accession (Human ortholog)
Chromosome
Chromosome position
Related human disease
RNA category pig
RNA pig tissue group specificity
RNA pig tissue group distribution
RNA pig tissue group specificity score
RNA pig tissue group specific NX
RNA pig brain regional specificity
RNA pig brain regional distribution
RNA pig brain regional specificity score
RNA pig brain regional specific pTPM
Annotation
UMAP cluster
Within tissue variation
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1.
Select data columns:
Gene
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Gene
i
Gene name, if available.
Gene synonym (Human ortholog)
Ensembl gene id
Ensembl gene id (Proteincoding human ortholog)
Gene description
Uniprot accession (Human ortholog)
Chromosome
Chromosome position
Related human disease
RNA category pig
Expand
RNA pig tissue group specificity
RNA pig tissue group distribution
RNA pig tissue group specificity score
RNA pig tissue group specific NX
RNA pig brain regional specificity
RNA pig brain regional distribution
RNA pig brain regional specificity score
RNA pig brain regional specific pTPM
Annotation
Expand
UMAP cluster
Within tissue variation
Pig Tissue RNA
Expand
Abdominal adipose tissue [NX]
Adrenal gland [NX]
Amygdala [NX]
Aorta [NX]
Bone marrow [NX]
Breast [NX]
Bronchus [NX]
Bulbourethral gland [NX]
Caudate [NX]
Cecum [NX]
Cerebellum [NX]
Cervix [NX]
Choroid plexus [NX]
Cingulate cortex [NX]
Colon [NX]
Cornea [NX]
Corpus callosum [NX]
Dorsal hippocampus [NX]
Dorsal spinal cord [NX]
Ductus deferens [NX]
Duodenum [NX]
Dura mater [NX]
Ear cartilage [NX]
Endometrium 1 [NX]
Entorhinal cortex [NX]
Epididymis [NX]
Esophagus [NX]
Facial adipose tissue [NX]
Fallopian tube [NX]
Gallbladder [NX]
Heart atrium [NX]
Heart valve [NX]
Heart wall [NX]
Hypothalamus [NX]
Ileum [NX]
Insular cortex [NX]
Jejunum [NX]
Joint cartilage [NX]
Kidney (cortex) [NX]
Kidney (medulla) [NX]
Larynx [NX]
Lens [NX]
Lip [NX]
Liver [NX]
Lung [NX]
Lymph node [NX]
Medulla [NX]
Midbrain [NX]
Motor cortex [NX]
Nasopharynx epithelium [NX]
Occipital cortex [NX]
Olfactory bulb [NX]
Olfactory epithelium [NX]
Oral mucosa [NX]
Ovary [NX]
Penis [NX]
Periaqueductal gray [NX]
Peritoneum [NX]
Pineal gland [NX]
Pituitary gland [NX]
Pleura [NX]
Pons [NX]
Prefrontal cortex [NX]
Prostate [NX]
Putamen [NX]
Rectum [NX]
Retina [NX]
Retrosplenial cortex [NX]
Salivary gland [NX]
Seminal vesicle [NX]
Septum [NX]
Skeletal muscle [NX]
Skin (back) [NX]
Skin (groin) [NX]
Smooth muscle (intestine) [NX]
Somatosensory cortex [NX]
Spleen [NX]
Stomach (lower) [NX]
Stomach (upper) [NX]
Subcutaneous adipose tissue [NX]
Subiculum [NX]
Substantia nigra [NX]
Superior colliculi [NX]
Synovial tissue [NX]
Temporal cortex [NX]
Testis [NX]
Thalamus [NX]
Thymus [NX]
Thyroid gland [NX]
Tongue [NX]
Tonsil [NX]
Trachea [NX]
Urethral gland [NX]
Urinary bladder [NX]
Vagus nerve [NX]
Ventral hippocampus [NX]
Ventral pallidum [NX]
Ventral spinal cord [NX]
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Gene
i
Gene name, if available.
Ensembl
x
Human ortholog
x
Gene description
x
RNA pig tissue group specificity
x
RNA pig tissue group distribution
x
RNA pig tissue group specific NX
x
KITLG
ENSSSCG00000035495
ENSG00000049130
Kit ligand precursor
Low tissue specificity
Detected in many
KLHL23
ENSSSCG00000015937
ENSG00000213160
Kelch like family member 23
Tissue enhanced
Detected in many
smooth muscle:
29.1
KLHL29
ENSSSCG00000008593
ENSG00000119771
Kelch like family member 29
Tissue enhanced
Detected in many
cartilage:
34.0
KRT14
ENSSSCG00000017448
ENSG00000186847
Keratin 14
Tissue enhanced
Detected in many
large intestine:
131.5
mouth:
166.7
skin:
199.4
KRT18
ENSSSCG00000000253
ENSG00000111057
Keratin 18
Tissue enhanced
Detected in many
gallbladder:
41.8
male glands:
48.4
salivary gland:
54.6
L1CAM
ENSSSCG00000012787
ENSG00000198910
L1 cell adhesion molecule
Tissue enhanced
Detected in many
ductus deferens:
55.0
kidney:
58.6
vagus nerve:
52.3
L3MBTL3
ENSSSCG00000004203
ENSG00000198945
L3MBTL3, histone methyl-lysine binding protein
Tissue enhanced
Detected in all
cartilage:
41.4
LAG3
ENSSSCG00000000688
ENSG00000089692
Lymphocyte activation gene 3 protein precursor
Tissue enhanced
Detected in many
cartilage:
22.4
lymphoid tissue:
18.4
LAMA3
ENSSSCG00000003709
ENSG00000053747
Laminin subunit alpha 3
Tissue enhanced
Detected in many
mesothelial tissue:
32.6
skin:
31.3
LAMA5
ENSSSCG00000032761
ENSG00000130702
Laminin subunit alpha 5
Low tissue specificity
Detected in all
LAMB1
ENSSSCG00000015444
ENSG00000091136
Laminin subunit beta 1
Low tissue specificity
Detected in all
LAPTM5
ENSSSCG00000025034
ENSG00000162511
Lysosomal protein transmembrane 5
Tissue enhanced
Detected in many
lymphoid tissue:
82.6
LAYN
ENSSSCG00000015022
ENSG00000204381
Layilin precursor
Tissue enhanced
Detected in many
cartilage:
29.8
pineal gland:
22.1
LBR
ENSSSCG00000032397
ENSG00000143815
Lamin B receptor
Tissue enhanced
Detected in all
lymphoid tissue:
40.7
LCP2
ENSSSCG00000017006
ENSG00000043462
Lymphocyte cytosolic protein 2
Tissue enhanced
Detected in many
lymphoid tissue:
115.5
stomach:
43.9
LDLRAD3
ENSSSCG00000013294
ENSG00000179241
Low density lipoprotein receptor class A domain containing 3
Tissue enhanced
Detected in all
cartilage:
58.8
LEF1
ENSSSCG00000009148
ENSG00000138795
Lymphoid enhancer-binding factor 1
Tissue enriched
Detected in many
lymphoid tissue:
206.1
LEPR
ENSSSCG00000025188
ENSG00000116678
Leptin receptor precursor
Tissue enhanced
Detected in many
bone marrow:
44.4
choroid plexus:
52.3
LFNG
ENSSSCG00000007572
ENSG00000106003
LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
Tissue enhanced
Detected in all
male glands:
81.6
LGALS2
ENSSSCG00000021728
ENSG00000100079
Galectin-2
Tissue enriched
Detected in some
gallbladder:
273.1
LGI4
ENSSSCG00000025126
ENSG00000153902
Leucine rich repeat LGI family member 4
Tissue enhanced
Detected in many
vagus nerve:
94.2
LGR4
ENSSSCG00000013335
ENSG00000205213
Leucine rich repeat containing G protein-coupled receptor 4
Tissue enhanced
Detected in many
stomach:
54.0
LHX6
ENSSSCG00000005530
ENSG00000106852
LIM homeobox 6
Tissue enhanced
Detected in many
cartilage:
32.4
LHX9
ENSSSCG00000010903
ENSG00000143355
LIM homeobox 9
Tissue enhanced
Detected in some
brain:
30.1
cartilage:
9.3
pineal gland:
12.3
LIMK1
ENSSSCG00000030378
ENSG00000106683
LIM domain kinase 1
Tissue enhanced
Detected in all
cartilage:
57.1
LIMS2
ENSSSCG00000015862
ENSG00000072163
LIM zinc finger domain containing 2
Tissue enhanced
Detected in many
smooth muscle:
121.2
LIN7A
ENSSSCG00000040348
ENSG00000111052
Lin-7 homolog A, crumbs cell polarity complex component
Tissue enhanced
Detected in all
testis:
45.9
LIPC
ENSSSCG00000004596
ENSG00000166035
Hepatic triacylglycerol lipase precursor
Group enriched
Detected in all
liver:
58.1
small intestine:
22.1
LIPG
ENSSSCG00000004509
ENSG00000101670
Endothelial lipase precursor
Tissue enhanced
Detected in all
adrenal gland:
49.3
ovary:
56.0
LMAN1L
ENSSSCG00000001899
ENSG00000140506
Lectin, mannose binding 1 like
Group enriched
Detected in some
esophagus:
79.5
male glands:
267.8
salivary gland:
90.9
LMO2
ENSSSCG00000013307
ENSG00000135363
LIM domain only 2
Low tissue specificity
Detected in many
LMOD1
ENSSSCG00000031201
ENSG00000163431
Leiomodin 1
Tissue enhanced
Detected in many
cervix:
83.2
smooth muscle:
104.3
LMTK2
ENSSSCG00000007599
ENSG00000164715
Lemur tyrosine kinase 2
Low tissue specificity
Detected in all
LNX1
ENSSSCG00000008838
ENSG00000072201
Ligand of numb-protein X 1
Tissue enhanced
Detected in many
brain:
26.7
male glands:
27.7
LONRF3
ENSSSCG00000012631
ENSG00000175556
LON peptidase N-terminal domain and ring finger 3
Low tissue specificity
Detected in all
LOX
ENSSSCG00000014232
ENSG00000113083
Protein-lysine 6-oxidase precursor
Tissue enhanced
Detected in many
cartilage:
54.1
ovary:
44.2
LOXL2
ENSSSCG00000033608
ENSG00000134013
Lysyl oxidase like 2
Tissue enhanced
Detected in many
cartilage:
85.0
LOXL3
ENSSSCG00000008266
ENSG00000115318
Lysyl oxidase like 3
Tissue enriched
Detected in many
cartilage:
82.9
LOXL4
ENSSSCG00000010532
ENSG00000138131
Lysyl oxidase like 4
Group enriched
Detected in many
cartilage:
29.1
ovary:
36.9
LRG1
ENSSSCG00000013514
ENSG00000171236
Leucine rich alpha-2-glycoprotein 1
Tissue enriched
Detected in many
liver:
64.1
LRRC32
ENSSSCG00000014869
ENSG00000137507
Leucine rich repeat containing 32
Tissue enhanced
Detected in many
mesothelial tissue:
43.0
LRRC38
ENSSSCG00000003449
ENSG00000162494
Leucine rich repeat containing 38
Tissue enhanced
Detected in some
brain:
10.0
cartilage:
8.6
epididymis:
5.9
heart:
7.6
LRRC3B
ENSSSCG00000011216
ENSG00000179796
Leucine rich repeat containing 3B
Tissue enhanced
Detected in many
brain:
16.9
male glands:
39.8
LRRC70
ENSSSCG00000037608
ENSG00000186105
Leucine rich repeat containing 70
Low tissue specificity
Detected in many
LRRTM3
ENSSSCG00000010232
ENSG00000198739
Leucine rich repeat transmembrane neuronal 3
Tissue enhanced
Detected in many
brain:
29.4
heart:
15.5
vagus nerve:
14.9
LSM10
ENSSSCG00000038916
ENSG00000181817
LSM10, U7 small nuclear RNA associated
Low tissue specificity
Detected in all
LTBP1
ENSSSCG00000008510
ENSG00000049323
Latent transforming growth factor beta binding protein 1
Tissue enhanced
Detected in many
cartilage:
91.5
ovary:
106.5
LTBP3
ENSSSCG00000012985
ENSG00000168056
Latent transforming growth factor beta binding protein 3
Tissue enhanced
Detected in all
cartilage:
96.6
LUM
ENSSSCG00000000916
ENSG00000139329
Lumican precursor
Tissue enhanced
Detected in many
cornea:
60.7
dura mater:
57.2
synovial tissue:
57.4
LURAP1L
ENSSSCG00000036360
ENSG00000153714
Leucine rich adaptor protein 1 like
Low tissue specificity
Detected in many
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