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Human disease related genes
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UMAP gene cluster
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Subclass
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Biological process
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Disease
Keyword
Chromosome
1
2
3
4
5
6
7
8
9
10
11
12
13
14
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MT
Unmapped
X
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External id
Variability
Variable
Not variable
Tissue
Any
Adipose tissue
Brain
Cartilage
Heart
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Lymphoid tissue
Male glands
Mesothelial tissue
Mouth
Skin
Small intestine
Stomach 1
Upper respiratory system
Cluster
1 - Brain neurotransmission
2 - Brain neurotransmission
3 - Brain cellular structure
4 - Brain development
5 - Intracellular signalling
6 - Brain uncharacterized
7 - Retinal
8 - Neurohormonal
9 - Testis spermatogenesis
10 - Housekeeping transcription
11 - Testis uncharacterized
12 - Metabolic
13 - Testis sperm
14 - Low abundant uncharacterized
15 - Testis uncharacterized
16 - Aorta uncharacterized
17 - Cilium structure
18 - Low abundant uncharacterized
19 - Housekeeping mitochondrial
20 - Hormonal
21 - Low abundant uncharacterized
22 - Housekeeping transcription
23 - Cilium structure
24 - Low abundant uncharacterized
25 - Low abundant uncharacterized
26 - Low abundant uncharacterized
27 - Low abundant uncharacterized
28 - Housekeeping mitochondrial translation
29 - Male tissue bacterial defense
30 - Housekeeping structural
31 - Housekeeping uncharacterized
32 - Transport
33 - Lens
34 - Prostate uncharacterized
35 - Low abundant uncharacterized
36 - Receptors uncharacterized
37 - Olfactory bulb
38 - Lung and thyroid development
39 - Kidney transport
40 - Testis
41 - Low abundant uncharacterized
42 - Low abundant uncharacterized
43 - Breast uncharacterized
44 - Housekeeping
45 - Thymus uncharacterized
46 - Skeletal muscle contraction
47 - Spleen uncharacterized
48 - Low abundant uncharacterized
49 - Heart contraction
50 - Muscle contraction
51 - Liver and kidney
52 - Housekeeping
53 - Housekeeping mitochondrial
54 - Interferons
55 - Low abundant uncharacterized
56 - Low abundant uncharacterized
57 - Skin
58 - Immune cells
59 - Squamous epithelium
60 - Not detected
61 - Enzymes and secretion
62 - Squamous epithelium
63 - Small intestine
64 - Gastrointestinal
65 - Epithelium
66 - Housekeeping mRNA
67 - Gastrointestinal
68 - Housekeeping protein processing
69 - Housekeeping
70 - Housekeeping
71 - Housekeeping regulation
72 - Digestive and respiratory defense
73 - Housekeeping cell cycle
74 - Extracellular matrix
75 - Housekeeping
76 - Housekeeping regulation
77 - Housekeeping defense
78 - Lymphoid T cells
79 - Lymphoid myeloid
80 - Heart uncharacterized
81 - Vasculature and connective tissue
82 - Lymphoid B cell
83 - Not detected
84 - Epithelium transcription regulation
Tissue group
Any
Adipose tissue
Adrenal gland
Aorta
Bone marrow
Brain
Breast
Cartilage
Cervix
Choroid plexus
Cornea
Ductus deferens
Dura mater
Endometrium
Epididymis
Esophagus
Fallopian tube
Gallbladder
Heart
Kidney
Large intestine
Lens
Liver
Lung
Lymphoid tissue
Male glands
Mesothelial tissue
Mouth
Ovary
Penis
Pineal gland
Pituitary gland
Retina
Salivary gland
Skeletal muscle
Skin
Small intestine
Smooth muscle
Stomach
Synovial tissue
Testis
Thyroid gland
Upper respiratory system
Urinary bladder
Vagus nerve
Category
Tissue enriched
Group enriched
Tissue enhanced
Low tissue specificity
Not detected
Detected in all
Detected in many
Detected in some
Detected in single
Is highest expressed
Brain region
Any
Amygdala
Basal ganglia
Cerebellum
Cerebral cortex
Corpus callosum
Hippocampal formation
Hypothalamus
Midbrain
Olfactory region
Pituitary gland
Pons and medulla
Retina
Spinal cord
Thalamus
Category
Region enriched
Group enriched
Region enhanced
Low region specificity
Not detected
Detected in all
Detected in many
Detected in some
Detected in single
Is highest expressed
Column
Gene
Position
Tissue specific score
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THE PIG PROTEOME
THE PIG ATLAS
TISSUE SPECIFIC PROTEOME
UMAP GENE CLUSTERING
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704 GENES FOUND
Gene
Gene
i
Gene name, if available.
Gene synonym (Human ortholog)
Ensembl gene id
Ensembl gene id (Proteincoding human ortholog)
Gene description
Uniprot accession (Human ortholog)
Chromosome
Chromosome position
Related human disease
RNA category pig
RNA pig tissue group specificity
RNA pig tissue group distribution
RNA pig tissue group specificity score
RNA pig tissue group specific NX
RNA pig brain regional specificity
RNA pig brain regional distribution
RNA pig brain regional specificity score
RNA pig brain regional specific pTPM
Annotation
UMAP cluster
Within tissue variation
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1.
Select data columns:
Gene
Expand
Gene
i
Gene name, if available.
Gene synonym (Human ortholog)
Ensembl gene id
Ensembl gene id (Proteincoding human ortholog)
Gene description
Uniprot accession (Human ortholog)
Chromosome
Chromosome position
Related human disease
RNA category pig
Expand
RNA pig tissue group specificity
RNA pig tissue group distribution
RNA pig tissue group specificity score
RNA pig tissue group specific NX
RNA pig brain regional specificity
RNA pig brain regional distribution
RNA pig brain regional specificity score
RNA pig brain regional specific pTPM
Annotation
Expand
UMAP cluster
Within tissue variation
Pig Tissue RNA
Expand
Abdominal adipose tissue [NX]
Adrenal gland [NX]
Amygdala [NX]
Aorta [NX]
Bone marrow [NX]
Breast [NX]
Bronchus [NX]
Bulbourethral gland [NX]
Caudate [NX]
Cecum [NX]
Cerebellum [NX]
Cervix [NX]
Choroid plexus [NX]
Cingulate cortex [NX]
Colon [NX]
Cornea [NX]
Corpus callosum [NX]
Dorsal hippocampus [NX]
Dorsal spinal cord [NX]
Ductus deferens [NX]
Duodenum [NX]
Dura mater [NX]
Ear cartilage [NX]
Endometrium 1 [NX]
Entorhinal cortex [NX]
Epididymis [NX]
Esophagus [NX]
Facial adipose tissue [NX]
Fallopian tube [NX]
Gallbladder [NX]
Heart atrium [NX]
Heart valve [NX]
Heart wall [NX]
Hypothalamus [NX]
Ileum [NX]
Insular cortex [NX]
Jejunum [NX]
Joint cartilage [NX]
Kidney (cortex) [NX]
Kidney (medulla) [NX]
Larynx [NX]
Lens [NX]
Lip [NX]
Liver [NX]
Lung [NX]
Lymph node [NX]
Medulla [NX]
Midbrain [NX]
Motor cortex [NX]
Nasopharynx epithelium [NX]
Occipital cortex [NX]
Olfactory bulb [NX]
Olfactory epithelium [NX]
Oral mucosa [NX]
Ovary [NX]
Penis [NX]
Periaqueductal gray [NX]
Peritoneum [NX]
Pineal gland [NX]
Pituitary gland [NX]
Pleura [NX]
Pons [NX]
Prefrontal cortex [NX]
Prostate [NX]
Putamen [NX]
Rectum [NX]
Retina [NX]
Retrosplenial cortex [NX]
Salivary gland [NX]
Seminal vesicle [NX]
Septum [NX]
Skeletal muscle [NX]
Skin (back) [NX]
Skin (groin) [NX]
Smooth muscle (intestine) [NX]
Somatosensory cortex [NX]
Spleen [NX]
Stomach (lower) [NX]
Stomach (upper) [NX]
Subcutaneous adipose tissue [NX]
Subiculum [NX]
Substantia nigra [NX]
Superior colliculi [NX]
Synovial tissue [NX]
Temporal cortex [NX]
Testis [NX]
Thalamus [NX]
Thymus [NX]
Thyroid gland [NX]
Tongue [NX]
Tonsil [NX]
Trachea [NX]
Urethral gland [NX]
Urinary bladder [NX]
Vagus nerve [NX]
Ventral hippocampus [NX]
Ventral pallidum [NX]
Ventral spinal cord [NX]
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Gene
i
Gene name, if available.
Ensembl
x
Human ortholog
x
Gene description
x
RNA pig tissue group specificity
x
RNA pig tissue group distribution
x
RNA pig tissue group specific NX
x
CCDC83
ENSSSCG00000014912
ENSG00000150676
Coiled-coil domain containing 83
Tissue enriched
Detected in some
testis:
70.9
CCER1
ENSSSCG00000039400
ENSG00000197651
Coiled-coil glutamate rich protein 1
Tissue enriched
Detected in single
testis:
99.2
CCIN
ENSSSCG00000005340
ENSG00000185972
Calicin
Tissue enriched
Detected in single
testis:
92.9
CCT6B
ENSSSCG00000022196
ENSG00000132141
Chaperonin containing TCP1 subunit 6B
Tissue enriched
Detected in many
testis:
50.4
CCT8L2
ENSSSCG00000016428
ENSG00000198445
Chaperonin containing TCP1 subunit 8 like 2
Tissue enriched
Detected in single
testis:
28.5
CELA2A
ENSSSCG00000003459
ENSG00000142615,ENSG00000215704
Chymotrypsin-like elastase family member 2A
Tissue enriched
Detected in some
testis:
29.8
CFAP97D1
ENSSSCG00000017373
ENSG00000231256
CFAP97 domain containing 1
Tissue enriched
Detected in some
testis:
143.7
CIB4
ENSSSCG00000008564
ENSG00000157884
Calcium and integrin binding family member 4
Tissue enhanced
Detected in many
testis:
34.9
CKLF
ENSSSCG00000031161
ENSG00000217555
Chemokine like factor
Tissue enriched
Detected in some
testis:
49.2
CMTM2
ENSSSCG00000031837
ENSG00000140932
CKLF like MARVEL transmembrane domain containing 2
Tissue enriched
Detected in some
testis:
101.3
CNBD1
ENSSSCG00000036161
ENSG00000176571
Cyclic nucleotide binding domain containing 1
Tissue enriched
Detected in single
testis:
12.6
CNBD2
ENSSSCG00000007313
ENSG00000149646
Cyclic nucleotide binding domain containing 2
Tissue enriched
Detected in some
testis:
57.2
COX6B2
ENSSSCG00000035612
ENSG00000160471
Cytochrome c oxidase subunit 6B2
Tissue enriched
Detected in some
testis:
128.8
COX7B2
ENSSSCG00000036922
ENSG00000170516
Cytochrome c oxidase subunit 7B2
Tissue enriched
Detected in some
testis:
51.0
COX8C
ENSSSCG00000002462
ENSG00000187581
Cytochrome c oxidase subunit 8C
Tissue enriched
Detected in some
testis:
30.8
CPB1
ENSSSCG00000011694
ENSG00000153002
Carboxypeptidase B precursor
Tissue enhanced
Detected in some
adipose tissue:
3.4
testis:
8.5
CXorf65
ENSSSCG00000030796
ENSG00000204165
Chromosome X open reading frame 65
Tissue enriched
Detected in single
testis:
17.7
CYLC1
ENSSSCG00000012455
ENSG00000183035
Cylicin 1
Tissue enriched
Detected in single
testis:
47.0
CYP19A1
ENSSSCG00000030168
ENSG00000137869
Aromatase 1
Tissue enriched
Detected in all
testis:
249.1
DAZL
ENSSSCG00000030671
ENSG00000092345
Deleted in azoospermia like
Tissue enriched
Detected in single
testis:
67.6
DDX4
ENSSSCG00000016913
ENSG00000152670
Probable ATP-dependent RNA helicase DDX4
Tissue enriched
Detected in some
testis:
73.8
DDX43
ENSSSCG00000004287
ENSG00000080007
DEAD-box helicase 43
Tissue enriched
Detected in single
testis:
21.5
DDX53
ENSSSCG00000012169
ENSG00000184735
DEAD-box helicase 53
Tissue enriched
Detected in some
testis:
25.4
DMC1
ENSSSCG00000000103
ENSG00000100206
DNA meiotic recombinase 1
Tissue enriched
Detected in some
testis:
24.8
DMRT1
ENSSSCG00000005236
ENSG00000137090
Doublesex- and mab-3-related transcription factor 1
Tissue enriched
Detected in some
testis:
35.7
DMRTB1
ENSSSCG00000003847
ENSG00000143006
DMRT like family B with proline rich C-terminal 1
Tissue enriched
Detected in some
testis:
28.8
DNAH8
ENSSSCG00000001588
ENSG00000124721
Dynein axonemal heavy chain 8
Tissue enriched
Detected in some
testis:
45.9
DUSP15
ENSSSCG00000007232
ENSG00000149599
Dual specificity phosphatase 15
Group enriched
Detected in many
testis:
74.0
vagus nerve:
20.7
DUSP21
ENSSSCG00000023500
ENSG00000189037
Dual specificity phosphatase 21
Tissue enriched
Detected in some
testis:
39.0
EFCAB13
ENSSSCG00000017305
ENSG00000178852
EF-hand calcium binding domain 13
Tissue enriched
Detected in single
testis:
22.7
EFCAB5
ENSSSCG00000017794
ENSG00000176927
EF-hand calcium binding domain 5
Tissue enriched
Detected in many
testis:
33.5
EFCAB9
ENSSSCG00000016995
ENSG00000214360
EF-hand calcium binding domain 9
Tissue enriched
Detected in many
testis:
35.2
EPO
ENSSSCG00000007673
ENSG00000130427
Erythropoietin
Tissue enhanced
Detected in some
testis:
5.3
EXD1
ENSSSCG00000004752
ENSG00000178997
Exonuclease 3'-5' domain containing 1
Tissue enhanced
Detected in many
epididymis:
12.9
testis:
21.5
FAM166A
ENSSSCG00000005848
ENSG00000188163
Family with sequence similarity 166 member A
Tissue enriched
Detected in single
testis:
62.8
FAM170B
ENSSSCG00000010387
ENSG00000172538
Family with sequence similarity 170 member B
Tissue enriched
Detected in single
testis:
35.4
FAM187B
ENSSSCG00000027989
ENSG00000177558
Family with sequence similarity 187 member B
Tissue enriched
Detected in single
testis:
54.1
FAM221B
ENSSSCG00000005324
ENSG00000204930
Family with sequence similarity 221 member B
Tissue enriched
Detected in many
testis:
43.6
FAM46D
ENSSSCG00000012450
ENSG00000174016
Family with sequence similarity 46 member D
Tissue enriched
Detected in single
testis:
32.6
FAM50B
ENSSSCG00000026323
ENSG00000145945
Family with sequence similarity 50 member B
Tissue enriched
Detected in single
testis:
94.1
FAM71A
ENSSSCG00000015596
ENSG00000162771
Family with sequence similarity 71 member A
Tissue enriched
Detected in single
testis:
88.0
FAM71B
ENSSSCG00000017057
ENSG00000170613
Family with sequence similarity 71 member B
Tissue enriched
Detected in many
testis:
77.7
FAM71F1
ENSSSCG00000016582
ENSG00000135248
Family with sequence similarity 71 member F1
Tissue enriched
Detected in some
testis:
76.6
FAM71F2
ENSSSCG00000016583
ENSG00000205085
Family with sequence similarity 71 member F2
Tissue enriched
Detected in some
testis:
119.0
FANCD2OS
ENSSSCG00000034155
ENSG00000163705
FANCD2 opposite strand
Tissue enriched
Detected in some
testis:
68.3
FATE1
ENSSSCG00000039345
ENSG00000147378
Fetal and adult testis-expressed transcript protein homolog
Tissue enriched
Detected in some
testis:
55.2
FBXO47
ENSSSCG00000036532
ENSG00000204952
F-box protein 47
Group enriched
Detected in some
retina:
7.4
testis:
25.8
FKBP6
ENSSSCG00000007702
ENSG00000077800
FK506 binding protein 6
Tissue enriched
Detected in single
testis:
66.6
FNDC11
ENSSSCG00000038651
ENSG00000125531
Fibronectin type III domain containing 11
Tissue enriched
Detected in single
testis:
93.7
FNDC8
ENSSSCG00000021617
ENSG00000073598
Fibronectin type III domain containing 8
Tissue enriched
Detected in single
testis:
90.8
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