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Human disease related genes
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UMAP gene cluster
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Subclass
Class
Biological process
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Disease
Keyword
Chromosome
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
MT
Unmapped
X
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External id
Variability
Variable
Not variable
Tissue
Any
Adipose tissue
Brain
Cartilage
Heart
Kidney
Large intestine
Lymphoid tissue
Male glands
Mesothelial tissue
Mouth
Skin
Small intestine
Stomach 1
Upper respiratory system
Cluster
1 - Brain neurotransmission
2 - Brain neurotransmission
3 - Brain cellular structure
4 - Brain development
5 - Intracellular signalling
6 - Brain uncharacterized
7 - Retinal
8 - Neurohormonal
9 - Testis spermatogenesis
10 - Housekeeping transcription
11 - Testis uncharacterized
12 - Metabolic
13 - Testis sperm
14 - Low abundant uncharacterized
15 - Testis uncharacterized
16 - Aorta uncharacterized
17 - Cilium structure
18 - Low abundant uncharacterized
19 - Housekeeping mitochondrial
20 - Hormonal
21 - Low abundant uncharacterized
22 - Housekeeping transcription
23 - Cilium structure
24 - Low abundant uncharacterized
25 - Low abundant uncharacterized
26 - Low abundant uncharacterized
27 - Low abundant uncharacterized
28 - Housekeeping mitochondrial translation
29 - Male tissue bacterial defense
30 - Housekeeping structural
31 - Housekeeping uncharacterized
32 - Transport
33 - Lens
34 - Prostate uncharacterized
35 - Low abundant uncharacterized
36 - Receptors uncharacterized
37 - Olfactory bulb
38 - Lung and thyroid development
39 - Kidney transport
40 - Testis
41 - Low abundant uncharacterized
42 - Low abundant uncharacterized
43 - Breast uncharacterized
44 - Housekeeping
45 - Thymus uncharacterized
46 - Skeletal muscle contraction
47 - Spleen uncharacterized
48 - Low abundant uncharacterized
49 - Heart contraction
50 - Muscle contraction
51 - Liver and kidney
52 - Housekeeping
53 - Housekeeping mitochondrial
54 - Interferons
55 - Low abundant uncharacterized
56 - Low abundant uncharacterized
57 - Skin
58 - Immune cells
59 - Squamous epithelium
60 - Not detected
61 - Enzymes and secretion
62 - Squamous epithelium
63 - Small intestine
64 - Gastrointestinal
65 - Epithelium
66 - Housekeeping mRNA
67 - Gastrointestinal
68 - Housekeeping protein processing
69 - Housekeeping
70 - Housekeeping
71 - Housekeeping regulation
72 - Digestive and respiratory defense
73 - Housekeeping cell cycle
74 - Extracellular matrix
75 - Housekeeping
76 - Housekeeping regulation
77 - Housekeeping defense
78 - Lymphoid T cells
79 - Lymphoid myeloid
80 - Heart uncharacterized
81 - Vasculature and connective tissue
82 - Lymphoid B cell
83 - Not detected
84 - Epithelium transcription regulation
Tissue group
Any
Adipose tissue
Adrenal gland
Aorta
Bone marrow
Brain
Breast
Cartilage
Cervix
Choroid plexus
Cornea
Ductus deferens
Dura mater
Endometrium
Epididymis
Esophagus
Fallopian tube
Gallbladder
Heart
Kidney
Large intestine
Lens
Liver
Lung
Lymphoid tissue
Male glands
Mesothelial tissue
Mouth
Ovary
Penis
Pineal gland
Pituitary gland
Retina
Salivary gland
Skeletal muscle
Skin
Small intestine
Smooth muscle
Stomach
Synovial tissue
Testis
Thyroid gland
Upper respiratory system
Urinary bladder
Vagus nerve
Category
Tissue enriched
Group enriched
Tissue enhanced
Low tissue specificity
Not detected
Detected in all
Detected in many
Detected in some
Detected in single
Is highest expressed
Brain region
Any
Amygdala
Basal ganglia
Cerebellum
Cerebral cortex
Corpus callosum
Hippocampal formation
Hypothalamus
Midbrain
Olfactory region
Pituitary gland
Pons and medulla
Retina
Spinal cord
Thalamus
Category
Region enriched
Group enriched
Region enhanced
Low region specificity
Not detected
Detected in all
Detected in many
Detected in some
Detected in single
Is highest expressed
Column
Gene
Position
Tissue specific score
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THE PIG PROTEOME
THE PIG ATLAS
TISSUE SPECIFIC PROTEOME
UMAP GENE CLUSTERING
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910 GENES FOUND
Gene
Gene
i
Gene name, if available.
Gene synonym (Human ortholog)
Ensembl gene id
Ensembl gene id (Proteincoding human ortholog)
Gene description
Uniprot accession (Human ortholog)
Chromosome
Chromosome position
Related human disease
RNA category pig
RNA pig tissue group specificity
RNA pig tissue group distribution
RNA pig tissue group specificity score
RNA pig tissue group specific NX
RNA pig brain regional specificity
RNA pig brain regional distribution
RNA pig brain regional specificity score
RNA pig brain regional specific pTPM
Annotation
UMAP cluster
Within tissue variation
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1.
Select data columns:
Gene
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Gene
i
Gene name, if available.
Gene synonym (Human ortholog)
Ensembl gene id
Ensembl gene id (Proteincoding human ortholog)
Gene description
Uniprot accession (Human ortholog)
Chromosome
Chromosome position
Related human disease
RNA category pig
Expand
RNA pig tissue group specificity
RNA pig tissue group distribution
RNA pig tissue group specificity score
RNA pig tissue group specific NX
RNA pig brain regional specificity
RNA pig brain regional distribution
RNA pig brain regional specificity score
RNA pig brain regional specific pTPM
Annotation
Expand
UMAP cluster
Within tissue variation
Pig Tissue RNA
Expand
Abdominal adipose tissue [NX]
Adrenal gland [NX]
Amygdala [NX]
Aorta [NX]
Bone marrow [NX]
Breast [NX]
Bronchus [NX]
Bulbourethral gland [NX]
Caudate [NX]
Cecum [NX]
Cerebellum [NX]
Cervix [NX]
Choroid plexus [NX]
Cingulate cortex [NX]
Colon [NX]
Cornea [NX]
Corpus callosum [NX]
Dorsal hippocampus [NX]
Dorsal spinal cord [NX]
Ductus deferens [NX]
Duodenum [NX]
Dura mater [NX]
Ear cartilage [NX]
Endometrium 1 [NX]
Entorhinal cortex [NX]
Epididymis [NX]
Esophagus [NX]
Facial adipose tissue [NX]
Fallopian tube [NX]
Gallbladder [NX]
Heart atrium [NX]
Heart valve [NX]
Heart wall [NX]
Hypothalamus [NX]
Ileum [NX]
Insular cortex [NX]
Jejunum [NX]
Joint cartilage [NX]
Kidney (cortex) [NX]
Kidney (medulla) [NX]
Larynx [NX]
Lens [NX]
Lip [NX]
Liver [NX]
Lung [NX]
Lymph node [NX]
Medulla [NX]
Midbrain [NX]
Motor cortex [NX]
Nasopharynx epithelium [NX]
Occipital cortex [NX]
Olfactory bulb [NX]
Olfactory epithelium [NX]
Oral mucosa [NX]
Ovary [NX]
Penis [NX]
Periaqueductal gray [NX]
Peritoneum [NX]
Pineal gland [NX]
Pituitary gland [NX]
Pleura [NX]
Pons [NX]
Prefrontal cortex [NX]
Prostate [NX]
Putamen [NX]
Rectum [NX]
Retina [NX]
Retrosplenial cortex [NX]
Salivary gland [NX]
Seminal vesicle [NX]
Septum [NX]
Skeletal muscle [NX]
Skin (back) [NX]
Skin (groin) [NX]
Smooth muscle (intestine) [NX]
Somatosensory cortex [NX]
Spleen [NX]
Stomach (lower) [NX]
Stomach (upper) [NX]
Subcutaneous adipose tissue [NX]
Subiculum [NX]
Substantia nigra [NX]
Superior colliculi [NX]
Synovial tissue [NX]
Temporal cortex [NX]
Testis [NX]
Thalamus [NX]
Thymus [NX]
Thyroid gland [NX]
Tongue [NX]
Tonsil [NX]
Trachea [NX]
Urethral gland [NX]
Urinary bladder [NX]
Vagus nerve [NX]
Ventral hippocampus [NX]
Ventral pallidum [NX]
Ventral spinal cord [NX]
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Gene
i
Gene name, if available.
Ensembl
x
Human ortholog
x
Gene description
x
RNA pig tissue group specificity
x
RNA pig tissue group distribution
x
RNA pig tissue group specific NX
x
NLGN1
ENSSSCG00000011756
ENSG00000169760
Neuroligin 1
Tissue enhanced
Detected in some
brain:
21.5
pineal gland:
6.9
NMB
ENSSSCG00000036907
ENSG00000197696
Neuromedin-B precursor
Group enriched
Detected in many
brain:
36.5
endometrium:
35.2
NOG
ENSSSCG00000036437
ENSG00000183691
Noggin precursor
Tissue enhanced
Detected in many
brain:
23.0
NOS1
ENSSSCG00000009856
ENSG00000089250
Nitric oxide synthase 1
Tissue enhanced
Detected in many
brain:
19.2
choroid plexus:
34.3
fallopian tube:
16.4
skeletal muscle:
18.1
NOVA1
ENSSSCG00000024396
ENSG00000139910
NOVA alternative splicing regulator 1
Tissue enhanced
Detected in many
brain:
35.0
synovial tissue:
21.8
NPTX2
ENSSSCG00000007603
ENSG00000106236
Neuronal pentraxin 2
Tissue enhanced
Detected in some
ovary:
51.1
pituitary gland:
22.2
salivary gland:
23.9
NPTXR
ENSSSCG00000000092
ENSG00000221890
Neuronal pentraxin receptor
Tissue enriched
Detected in many
brain:
54.3
NRIP3
ENSSSCG00000014570
ENSG00000175352
Nuclear receptor interacting protein 3
Tissue enhanced
Detected in many
brain:
28.4
salivary gland:
14.1
NRN1
ENSSSCG00000026211
ENSG00000124785
Neuritin precursor
Group enriched
Detected in some
brain:
38.2
retina:
10.5
NRSN1
ENSSSCG00000021696
ENSG00000152954
Neurensin 1
Tissue enriched
Detected in many
brain:
50.9
NRSN2
ENSSSCG00000031519
ENSG00000125841
Neurensin 2
Tissue enhanced
Detected in all
brain:
24.3
NRXN1
ENSSSCG00000008419
ENSG00000179915
Neurexin 1
Tissue enhanced
Detected in many
bone marrow:
25.5
brain:
62.7
pituitary gland:
24.4
NSF
ENSSSCG00000017316
ENSG00000073969
Vesicle-fusing ATPase
Group enriched
Detected in all
brain:
64.6
pineal gland:
31.4
pituitary gland:
17.8
retina:
24.6
NSG1
ENSSSCG00000024892
ENSG00000168824
Neuronal vesicle trafficking associated 1
Tissue enhanced
Detected in many
brain:
56.3
pineal gland:
28.5
pituitary gland:
27.4
NSG2
ENSSSCG00000016979
ENSG00000170091
Neuronal vesicle trafficking associated 2
Group enriched
Detected in some
brain:
78.7
pituitary gland:
20.0
NTM
ENSSSCG00000015253
ENSG00000182667
Neurotrimin
Group enriched
Detected in many
brain:
38.2
gallbladder:
14.3
lens:
17.6
pineal gland:
30.5
retina:
15.2
NTNG1
ENSSSCG00000006852
ENSG00000162631
Netrin G1
Tissue enhanced
Detected in many
brain:
38.4
retina:
11.0
testis:
11.8
NTNG2
ENSSSCG00000005723
ENSG00000196358
Netrin G2
Tissue enhanced
Detected in many
brain:
20.3
lens:
22.6
retina:
62.4
NTRK3
ENSSSCG00000005106
ENSG00000140538
Neurotrophic receptor tyrosine kinase 3
Tissue enhanced
Detected in many
brain:
32.2
ovary:
35.6
NTS
ENSSSCG00000000932
ENSG00000133636
Neurotensin
Group enriched
Detected in some
brain:
39.6
pituitary gland:
46.5
NXPH1
ENSSSCG00000037207
ENSG00000122584
Neurexophilin 1
Tissue enriched
Detected in some
brain:
19.2
NXPH2
ENSSSCG00000040715
ENSG00000144227
Neurexophilin 2
Tissue enhanced
Detected in many
brain:
10.7
male glands:
16.3
salivary gland:
10.6
upper respiratory system:
9.4
NXPH4
ENSSSCG00000039966
ENSG00000182379
Neurexophilin 4
Tissue enhanced
Detected in some
adrenal gland:
9.4
brain:
19.3
pineal gland:
14.3
skin:
9.1
NYAP2
ENSSSCG00000016239
ENSG00000144460
Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 2
Tissue enhanced
Detected in some
brain:
19.6
lens:
28.2
pineal gland:
19.3
retina:
18.4
OCIAD2
ENSSSCG00000008829
ENSG00000145247
OCIA domain containing 2
Tissue enhanced
Detected in all
liver:
55.0
OGDHL
ENSSSCG00000010394
ENSG00000197444
Oxoglutarate dehydrogenase like
Tissue enhanced
Detected in some
brain:
15.2
liver:
28.0
pineal gland:
12.1
pituitary gland:
11.6
retina:
12.1
OLFM1
ENSSSCG00000029715
ENSG00000130558
Olfactomedin 1
Tissue enhanced
Detected in many
brain:
87.2
lens:
29.0
OLFM2
ENSSSCG00000027434
ENSG00000105088
Olfactomedin 2
Tissue enriched
Detected in all
ovary:
121.9
OLFM3
ENSSSCG00000006858
ENSG00000118733
Olfactomedin 3
Group enriched
Detected in some
brain:
33.3
ovary:
12.9
OPCML
ENSSSCG00000037534
ENSG00000183715
Opioid binding protein/cell adhesion molecule like
Tissue enriched
Detected in some
brain:
42.1
OPRK1
ENSSSCG00000006264
ENSG00000082556
Opioid receptor kappa 1
Tissue enhanced
Detected in many
brain:
17.7
kidney:
16.8
pituitary gland:
15.5
OPRM1
ENSSSCG00000004074
ENSG00000112038
Mu-type opioid receptor
Tissue enriched
Detected in some
brain:
11.7
OSBP2
ENSSSCG00000010015
ENSG00000184792
Oxysterol binding protein 2
Group enriched
Detected in some
brain:
16.1
lens:
22.2
retina:
60.4
testis:
40.6
OTUD7A
ENSSSCG00000004840
ENSG00000169918
OTU deubiquitinase 7A
Group enriched
Detected in many
brain:
15.3
male glands:
22.8
PACSIN1
ENSSSCG00000027053
ENSG00000124507
Protein kinase C and casein kinase substrate in neurons 1
Group enriched
Detected in many
brain:
36.8
pineal gland:
17.0
retina:
28.3
PANK2
ENSSSCG00000007142
ENSG00000125779
Pantothenate kinase 2
Low tissue specificity
Detected in all
PANX2
ENSSSCG00000000975
ENSG00000073150
Pannexin 2
Tissue enhanced
Detected in many
brain:
28.5
PAQR3
ENSSSCG00000009259
ENSG00000163291
Progestin and adipoQ receptor family member 3
Low tissue specificity
Detected in all
PAQR9
ENSSSCG00000011685
ENSG00000188582
Progestin and adipoQ receptor family member 9
Tissue enhanced
Detected in some
heart:
10.3
liver:
11.6
ovary:
15.5
retina:
13.4
testis:
25.3
PCBP3
ENSSSCG00000023041
ENSG00000183570
Poly(rC) binding protein 3
Group enriched
Detected in some
brain:
48.7
pineal gland:
16.8
retina:
65.0
testis:
28.0
PCDH10
ENSSSCG00000036125
ENSG00000138650
Protocadherin 10
Tissue enhanced
Detected in some
adrenal gland:
9.6
brain:
27.1
fallopian tube:
7.6
PCDH15
ENSSSCG00000010426
ENSG00000150275
Protocadherin related 15
Tissue enhanced
Detected in some
lens:
24.5
ovary:
13.8
retina:
67.0
PCDHA11
ENSSSCG00000024998
ENSG00000249158
Protocadherin alpha 11
Tissue enhanced
Detected in some
brain:
11.6
pineal gland:
7.4
pituitary gland:
8.9
retina:
9.1
PCNX2
ENSSSCG00000010165
ENSG00000135749
Pecanex homolog 2
Group enriched
Detected in some
brain:
36.5
pineal gland:
9.9
retina:
13.6
PCSK1
ENSSSCG00000014169
ENSG00000175426
Neuroendocrine convertase 1 precursor
Group enriched
Detected in some
brain:
28.5
pineal gland:
47.8
pituitary gland:
42.7
PCSK2
ENSSSCG00000007083
ENSG00000125851
Neuroendocrine convertase 2 precursor
Tissue enhanced
Detected in some
brain:
38.0
pituitary gland:
51.1
thyroid gland:
19.5
PDXK
ENSSSCG00000034758
ENSG00000160209
Pyridoxal kinase
Tissue enhanced
Detected in all
brain:
25.4
PDXP
ENSSSCG00000034632
ENSG00000241360
Pyridoxal phosphatase
Tissue enhanced
Detected in many
brain:
33.1
PDYN
ENSSSCG00000037684
ENSG00000101327
Proenkephalin-B preproprotein
Group enriched
Detected in some
brain:
49.1
cornea:
60.7
PDZD4
ENSSSCG00000012785
ENSG00000067840
PDZ domain containing 4
Tissue enriched
Detected in some
brain:
40.9
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