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Human disease related genes
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UMAP gene cluster
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Keyword
Chromosome
1
2
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6
7
8
9
10
11
12
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MT
Unmapped
X
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External id
Variability
Variable
Not variable
Tissue
Any
Adipose tissue
Brain
Cartilage
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Lymphoid tissue
Male glands
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Mouth
Skin
Small intestine
Stomach 1
Upper respiratory system
Cluster
1 - Brain neurotransmission
2 - Brain neurotransmission
3 - Brain cellular structure
4 - Brain development
5 - Intracellular signalling
6 - Brain uncharacterized
7 - Retinal
8 - Neurohormonal
9 - Testis spermatogenesis
10 - Housekeeping transcription
11 - Testis uncharacterized
12 - Metabolic
13 - Testis sperm
14 - Low abundant uncharacterized
15 - Testis uncharacterized
16 - Aorta uncharacterized
17 - Cilium structure
18 - Low abundant uncharacterized
19 - Housekeeping mitochondrial
20 - Hormonal
21 - Low abundant uncharacterized
22 - Housekeeping transcription
23 - Cilium structure
24 - Low abundant uncharacterized
25 - Low abundant uncharacterized
26 - Low abundant uncharacterized
27 - Low abundant uncharacterized
28 - Housekeeping mitochondrial translation
29 - Male tissue bacterial defense
30 - Housekeeping structural
31 - Housekeeping uncharacterized
32 - Transport
33 - Lens
34 - Prostate uncharacterized
35 - Low abundant uncharacterized
36 - Receptors uncharacterized
37 - Olfactory bulb
38 - Lung and thyroid development
39 - Kidney transport
40 - Testis
41 - Low abundant uncharacterized
42 - Low abundant uncharacterized
43 - Breast uncharacterized
44 - Housekeeping
45 - Thymus uncharacterized
46 - Skeletal muscle contraction
47 - Spleen uncharacterized
48 - Low abundant uncharacterized
49 - Heart contraction
50 - Muscle contraction
51 - Liver and kidney
52 - Housekeeping
53 - Housekeeping mitochondrial
54 - Interferons
55 - Low abundant uncharacterized
56 - Low abundant uncharacterized
57 - Skin
58 - Immune cells
59 - Squamous epithelium
60 - Not detected
61 - Enzymes and secretion
62 - Squamous epithelium
63 - Small intestine
64 - Gastrointestinal
65 - Epithelium
66 - Housekeeping mRNA
67 - Gastrointestinal
68 - Housekeeping protein processing
69 - Housekeeping
70 - Housekeeping
71 - Housekeeping regulation
72 - Digestive and respiratory defense
73 - Housekeeping cell cycle
74 - Extracellular matrix
75 - Housekeeping
76 - Housekeeping regulation
77 - Housekeeping defense
78 - Lymphoid T cells
79 - Lymphoid myeloid
80 - Heart uncharacterized
81 - Vasculature and connective tissue
82 - Lymphoid B cell
83 - Not detected
84 - Epithelium transcription regulation
Tissue group
Any
Adipose tissue
Adrenal gland
Aorta
Bone marrow
Brain
Breast
Cartilage
Cervix
Choroid plexus
Cornea
Ductus deferens
Dura mater
Endometrium
Epididymis
Esophagus
Fallopian tube
Gallbladder
Heart
Kidney
Large intestine
Lens
Liver
Lung
Lymphoid tissue
Male glands
Mesothelial tissue
Mouth
Ovary
Penis
Pineal gland
Pituitary gland
Retina
Salivary gland
Skeletal muscle
Skin
Small intestine
Smooth muscle
Stomach
Synovial tissue
Testis
Thyroid gland
Upper respiratory system
Urinary bladder
Vagus nerve
Category
Tissue enriched
Group enriched
Tissue enhanced
Low tissue specificity
Not detected
Detected in all
Detected in many
Detected in some
Detected in single
Is highest expressed
Brain region
Any
Amygdala
Basal ganglia
Cerebellum
Cerebral cortex
Corpus callosum
Hippocampal formation
Hypothalamus
Midbrain
Olfactory region
Pituitary gland
Pons and medulla
Retina
Spinal cord
Thalamus
Category
Region enriched
Group enriched
Region enhanced
Low region specificity
Not detected
Detected in all
Detected in many
Detected in some
Detected in single
Is highest expressed
Column
Gene
Position
Tissue specific score
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THE PIG PROTEOME
THE PIG ATLAS
TISSUE SPECIFIC PROTEOME
UMAP GENE CLUSTERING
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208 GENES FOUND
Gene
Gene
i
Gene name, if available.
Gene synonym (Human ortholog)
Ensembl gene id
Ensembl gene id (Proteincoding human ortholog)
Gene description
Uniprot accession (Human ortholog)
Chromosome
Chromosome position
Related human disease
RNA category pig
RNA pig tissue group specificity
RNA pig tissue group distribution
RNA pig tissue group specificity score
RNA pig tissue group specific NX
RNA pig brain regional specificity
RNA pig brain regional distribution
RNA pig brain regional specificity score
RNA pig brain regional specific pTPM
Annotation
UMAP cluster
Within tissue variation
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1.
Select data columns:
Gene
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Gene
i
Gene name, if available.
Gene synonym (Human ortholog)
Ensembl gene id
Ensembl gene id (Proteincoding human ortholog)
Gene description
Uniprot accession (Human ortholog)
Chromosome
Chromosome position
Related human disease
RNA category pig
Expand
RNA pig tissue group specificity
RNA pig tissue group distribution
RNA pig tissue group specificity score
RNA pig tissue group specific NX
RNA pig brain regional specificity
RNA pig brain regional distribution
RNA pig brain regional specificity score
RNA pig brain regional specific pTPM
Annotation
Expand
UMAP cluster
Within tissue variation
Pig Tissue RNA
Expand
Abdominal adipose tissue [NX]
Adrenal gland [NX]
Amygdala [NX]
Aorta [NX]
Bone marrow [NX]
Breast [NX]
Bronchus [NX]
Bulbourethral gland [NX]
Caudate [NX]
Cecum [NX]
Cerebellum [NX]
Cervix [NX]
Choroid plexus [NX]
Cingulate cortex [NX]
Colon [NX]
Cornea [NX]
Corpus callosum [NX]
Dorsal hippocampus [NX]
Dorsal spinal cord [NX]
Ductus deferens [NX]
Duodenum [NX]
Dura mater [NX]
Ear cartilage [NX]
Endometrium 1 [NX]
Entorhinal cortex [NX]
Epididymis [NX]
Esophagus [NX]
Facial adipose tissue [NX]
Fallopian tube [NX]
Gallbladder [NX]
Heart atrium [NX]
Heart valve [NX]
Heart wall [NX]
Hypothalamus [NX]
Ileum [NX]
Insular cortex [NX]
Jejunum [NX]
Joint cartilage [NX]
Kidney (cortex) [NX]
Kidney (medulla) [NX]
Larynx [NX]
Lens [NX]
Lip [NX]
Liver [NX]
Lung [NX]
Lymph node [NX]
Medulla [NX]
Midbrain [NX]
Motor cortex [NX]
Nasopharynx epithelium [NX]
Occipital cortex [NX]
Olfactory bulb [NX]
Olfactory epithelium [NX]
Oral mucosa [NX]
Ovary [NX]
Penis [NX]
Periaqueductal gray [NX]
Peritoneum [NX]
Pineal gland [NX]
Pituitary gland [NX]
Pleura [NX]
Pons [NX]
Prefrontal cortex [NX]
Prostate [NX]
Putamen [NX]
Rectum [NX]
Retina [NX]
Retrosplenial cortex [NX]
Salivary gland [NX]
Seminal vesicle [NX]
Septum [NX]
Skeletal muscle [NX]
Skin (back) [NX]
Skin (groin) [NX]
Smooth muscle (intestine) [NX]
Somatosensory cortex [NX]
Spleen [NX]
Stomach (lower) [NX]
Stomach (upper) [NX]
Subcutaneous adipose tissue [NX]
Subiculum [NX]
Substantia nigra [NX]
Superior colliculi [NX]
Synovial tissue [NX]
Temporal cortex [NX]
Testis [NX]
Thalamus [NX]
Thymus [NX]
Thyroid gland [NX]
Tongue [NX]
Tonsil [NX]
Trachea [NX]
Urethral gland [NX]
Urinary bladder [NX]
Vagus nerve [NX]
Ventral hippocampus [NX]
Ventral pallidum [NX]
Ventral spinal cord [NX]
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Gene
i
Gene name, if available.
Ensembl
x
Human ortholog
x
Gene description
x
RNA pig tissue group specificity
x
RNA pig tissue group distribution
x
RNA pig tissue group specific NX
x
ACSL4
ENSSSCG00000012583
ENSG00000068366
Long-chain-fatty-acid--CoA ligase 4
Tissue enriched
Detected in all
ovary:
135.8
ADAT3
ENSSSCG00000038810
ENSG00000213638
Adenosine deaminase, tRNA specific 3
Low tissue specificity
Detected in all
AFF2
ENSSSCG00000012730
ENSG00000155966
AF4/FMR2 family member 2
Tissue enhanced
Detected in many
epididymis:
37.8
male glands:
53.3
AGRP
ENSSSCG00000002775
ENSG00000159723
Agouti-related protein
Group enriched
Detected in some
brain:
9.1
pineal gland:
7.7
pituitary gland:
2.4
AHDC1
ENSSSCG00000003579
ENSG00000126705
AT-hook DNA binding motif containing 1
Low tissue specificity
Detected in all
ALDH2
ENSSSCG00000009889
ENSG00000111275
Aldehyde dehydrogenase, mitochondrial
Tissue enhanced
Detected in all
liver:
117.1
ALKBH8
ENSSSCG00000024628
ENSG00000137760
AlkB homolog 8, tRNA methyltransferase
Low tissue specificity
Detected in all
ARHGEF6
ENSSSCG00000030460
ENSG00000129675
Rac/Cdc42 guanine nucleotide exchange factor 6
Low tissue specificity
Detected in all
ARID1A
ENSSSCG00000003559
ENSG00000117713
AT-rich interaction domain 1A
Low tissue specificity
Detected in all
ARID1B
ENSSSCG00000004064
ENSG00000049618
AT-rich interaction domain 1B
Low tissue specificity
Detected in all
ARX
ENSSSCG00000020801
ENSG00000004848
Aristaless related homeobox
Group enriched
Detected in some
brain:
19.5
ovary:
19.2
skeletal muscle:
16.1
ASH1L
ENSSSCG00000006508
ENSG00000116539
ASH1 like histone lysine methyltransferase
Low tissue specificity
Detected in all
ATP6AP2
ENSSSCG00000012247
ENSG00000182220
ATPase H+ transporting accessory protein 2
Low tissue specificity
Detected in all
AUTS2
ENSSSCG00000007727
ENSG00000158321
Autism susceptibility gene 2 protein
Tissue enhanced
Detected in many
cartilage:
165.4
male glands:
64.3
BDNF
ENSSSCG00000013333
ENSG00000176697
Brain-derived neurotrophic factor
Tissue enhanced
Detected in many
brain:
18.1
pituitary gland:
7.9
BRWD3
ENSSSCG00000025156
ENSG00000165288
Bromodomain and WD repeat domain containing 3
Low tissue specificity
Detected in all
C12orf4
ENSSSCG00000000723
ENSG00000047621
homolog isoform 2
Low tissue specificity
Detected in all
C4A
ENSSSCG00000001427
ENSG00000224389,ENSG00000244731
Complement C4-A precursor
Tissue enhanced
Detected in many
adipose tissue:
79.1
liver:
104.7
CACNG2
ENSSSCG00000033551
ENSG00000166862
Calcium voltage-gated channel auxiliary subunit gamma 2
Tissue enhanced
Detected in some
brain:
15.4
retina:
5.4
CAMK2A
ENSSSCG00000014443
ENSG00000070808
Calcium/calmodulin dependent protein kinase II alpha
Tissue enriched
Detected in some
brain:
130.1
CAMK2B
ENSSSCG00000039535
ENSG00000058404
Calcium/calmodulin dependent protein kinase II beta
Tissue enhanced
Detected in some
brain:
59.2
heart:
18.2
skeletal muscle:
17.4
CC2D1A
ENSSSCG00000013761
ENSG00000132024
Coiled-coil and C2 domain-containing protein 1A
Low tissue specificity
Detected in all
CDH15
ENSSSCG00000002642
ENSG00000129910
Cadherin 15
Tissue enhanced
Detected in many
brain:
17.2
skeletal muscle:
19.1
CHD8
ENSSSCG00000002127
ENSG00000100888
Chromodomain helicase DNA binding protein 8
Low tissue specificity
Detected in all
CHEK2
ENSSSCG00000034864
ENSG00000183765
Serine/threonine-protein kinase Chk2
Low tissue specificity
Detected in all
CHI3L1
ENSSSCG00000015476
ENSG00000133048
Chitinase-3-like protein 1 precursor
Group enriched
Detected in some
cartilage:
58.5
lung:
39.6
synovial tissue:
21.1
upper respiratory system:
18.7
CHRM3
ENSSSCG00000026176
ENSG00000133019
Muscarinic acetylcholine receptor M3
Tissue enhanced
Detected in many
salivary gland:
36.8
smooth muscle:
32.6
CIC
ENSSSCG00000003030
ENSG00000079432
Capicua transcriptional repressor
Low tissue specificity
Detected in all
CLCN4
ENSSSCG00000024809
ENSG00000073464
Chloride voltage-gated channel 4
Tissue enhanced
Detected in many
brain:
26.5
lens:
27.1
pineal gland:
12.6
retina:
12.6
CLIC2
ENSSSCG00000039998
ENSG00000155962
Chloride intracellular channel protein 2
Low tissue specificity
Detected in all
CNKSR2
ENSSSCG00000012164
ENSG00000149970
Connector enhancer of kinase suppressor of Ras 2
Tissue enhanced
Detected in many
brain:
46.2
lens:
24.9
vagus nerve:
15.1
CNTNAP2
ENSSSCG00000037981
ENSG00000174469
Contactin associated protein like 2
Tissue enhanced
Detected in many
brain:
24.4
cervix:
19.4
pituitary gland:
25.1
thyroid gland:
18.3
COL4A3BP
ENSSSCG00000014081
ENSG00000113163
Collagen type IV alpha 3 binding protein
Low tissue specificity
Detected in all
COMT
ENSSSCG00000010132
ENSG00000093010
Catechol O-methyltransferase
Tissue enhanced
Detected in all
liver:
118.4
CRADD
ENSSSCG00000000910
ENSG00000169372
Suppressor of cytokine signaling 2
Low tissue specificity
Detected in all
CRBN
ENSSSCG00000011530
ENSG00000113851
Cereblon
Tissue enhanced
Detected in all
lens:
55.5
CTCF
ENSSSCG00000024253
ENSG00000102974
Transcriptional repressor CTCF
Low tissue specificity
Detected in all
CTNNB1
ENSSSCG00000011274
ENSG00000168036
Catenin beta-1
Low tissue specificity
Detected in all
CUL4B
ENSSSCG00000029478
ENSG00000158290
Cullin 4B
Tissue enhanced
Detected in all
pituitary gland:
69.0
DDX3X
ENSSSCG00000012252
ENSG00000215301
ATP-dependent RNA helicase DDX3X
Low tissue specificity
Detected in all
DEAF1
ENSSSCG00000012850
ENSG00000177030
DEAF1, transcription factor
Low tissue specificity
Detected in all
DIP2B
ENSSSCG00000029196
ENSG00000066084
Disco interacting protein 2 homolog B
Low tissue specificity
Detected in all
DISC1
ENSSSCG00000010170
ENSG00000162946
Disrupted in schizophrenia 1
Tissue enhanced
Detected in all
lens:
47.8
DLG3
ENSSSCG00000012375
ENSG00000082458
Discs large MAGUK scaffold protein 3
Tissue enhanced
Detected in many
male glands:
43.5
DNAAF4
ENSSSCG00000004608
ENSG00000256061
Dynein axonemal assembly factor 4
Tissue enhanced
Detected in many
lens:
23.0
testis:
23.0
DOCK8
ENSSSCG00000005240
ENSG00000107099
Dedicator of cytokinesis 8
Tissue enhanced
Detected in many
lymphoid tissue:
48.5
DPP6
ENSSSCG00000016423
ENSG00000130226
Dipeptidyl peptidase like 6
Tissue enriched
Detected in some
brain:
44.0
DRD2
ENSSSCG00000015048
ENSG00000149295
D(2) dopamine receptor
Tissue enhanced
Detected in many
brain:
56.0
pineal gland:
16.5
pituitary gland:
32.6
DRD3
ENSSSCG00000011911
ENSG00000151577
Dopamine receptor D3
Tissue enriched
Detected in some
brain:
26.2
DRD4
ENSSSCG00000012851
ENSG00000069696
Dopamine receptor D4
Tissue enriched
Detected in some
retina:
113.1
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