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Human disease related genes
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UMAP gene cluster
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Keyword
Chromosome
1
2
3
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5
6
7
8
9
10
11
12
13
14
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MT
Unmapped
X
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External id
Variability
Variable
Not variable
Tissue
Any
Adipose tissue
Brain
Cartilage
Heart
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Lymphoid tissue
Male glands
Mesothelial tissue
Mouth
Skin
Small intestine
Stomach 1
Upper respiratory system
Cluster
1 - Brain neurotransmission
2 - Brain neurotransmission
3 - Brain cellular structure
4 - Brain development
5 - Intracellular signalling
6 - Brain uncharacterized
7 - Retinal
8 - Neurohormonal
9 - Testis spermatogenesis
10 - Housekeeping transcription
11 - Testis uncharacterized
12 - Metabolic
13 - Testis sperm
14 - Low abundant uncharacterized
15 - Testis uncharacterized
16 - Aorta uncharacterized
17 - Cilium structure
18 - Low abundant uncharacterized
19 - Housekeeping mitochondrial
20 - Hormonal
21 - Low abundant uncharacterized
22 - Housekeeping transcription
23 - Cilium structure
24 - Low abundant uncharacterized
25 - Low abundant uncharacterized
26 - Low abundant uncharacterized
27 - Low abundant uncharacterized
28 - Housekeeping mitochondrial translation
29 - Male tissue bacterial defense
30 - Housekeeping structural
31 - Housekeeping uncharacterized
32 - Transport
33 - Lens
34 - Prostate uncharacterized
35 - Low abundant uncharacterized
36 - Receptors uncharacterized
37 - Olfactory bulb
38 - Lung and thyroid development
39 - Kidney transport
40 - Testis
41 - Low abundant uncharacterized
42 - Low abundant uncharacterized
43 - Breast uncharacterized
44 - Housekeeping
45 - Thymus uncharacterized
46 - Skeletal muscle contraction
47 - Spleen uncharacterized
48 - Low abundant uncharacterized
49 - Heart contraction
50 - Muscle contraction
51 - Liver and kidney
52 - Housekeeping
53 - Housekeeping mitochondrial
54 - Interferons
55 - Low abundant uncharacterized
56 - Low abundant uncharacterized
57 - Skin
58 - Immune cells
59 - Squamous epithelium
60 - Not detected
61 - Enzymes and secretion
62 - Squamous epithelium
63 - Small intestine
64 - Gastrointestinal
65 - Epithelium
66 - Housekeeping mRNA
67 - Gastrointestinal
68 - Housekeeping protein processing
69 - Housekeeping
70 - Housekeeping
71 - Housekeeping regulation
72 - Digestive and respiratory defense
73 - Housekeeping cell cycle
74 - Extracellular matrix
75 - Housekeeping
76 - Housekeeping regulation
77 - Housekeeping defense
78 - Lymphoid T cells
79 - Lymphoid myeloid
80 - Heart uncharacterized
81 - Vasculature and connective tissue
82 - Lymphoid B cell
83 - Not detected
84 - Epithelium transcription regulation
Tissue group
Any
Adipose tissue
Adrenal gland
Aorta
Bone marrow
Brain
Breast
Cartilage
Cervix
Choroid plexus
Cornea
Ductus deferens
Dura mater
Endometrium
Epididymis
Esophagus
Fallopian tube
Gallbladder
Heart
Kidney
Large intestine
Lens
Liver
Lung
Lymphoid tissue
Male glands
Mesothelial tissue
Mouth
Ovary
Penis
Pineal gland
Pituitary gland
Retina
Salivary gland
Skeletal muscle
Skin
Small intestine
Smooth muscle
Stomach
Synovial tissue
Testis
Thyroid gland
Upper respiratory system
Urinary bladder
Vagus nerve
Category
Tissue enriched
Group enriched
Tissue enhanced
Low tissue specificity
Not detected
Detected in all
Detected in many
Detected in some
Detected in single
Is highest expressed
Brain region
Any
Amygdala
Basal ganglia
Cerebellum
Cerebral cortex
Corpus callosum
Hippocampal formation
Hypothalamus
Midbrain
Olfactory region
Pituitary gland
Pons and medulla
Retina
Spinal cord
Thalamus
Category
Region enriched
Group enriched
Region enhanced
Low region specificity
Not detected
Detected in all
Detected in many
Detected in some
Detected in single
Is highest expressed
Column
Gene
Position
Tissue specific score
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THE PIG PROTEOME
THE PIG ATLAS
TISSUE SPECIFIC PROTEOME
UMAP GENE CLUSTERING
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270 GENES FOUND
Gene
Gene
i
Gene name, if available.
Gene synonym (Human ortholog)
Ensembl gene id
Ensembl gene id (Proteincoding human ortholog)
Gene description
Uniprot accession (Human ortholog)
Chromosome
Chromosome position
Related human disease
RNA category pig
RNA pig tissue group specificity
RNA pig tissue group distribution
RNA pig tissue group specificity score
RNA pig tissue group specific NX
RNA pig brain regional specificity
RNA pig brain regional distribution
RNA pig brain regional specificity score
RNA pig brain regional specific pTPM
Annotation
UMAP cluster
Within tissue variation
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Select data columns:
Gene
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Gene
i
Gene name, if available.
Gene synonym (Human ortholog)
Ensembl gene id
Ensembl gene id (Proteincoding human ortholog)
Gene description
Uniprot accession (Human ortholog)
Chromosome
Chromosome position
Related human disease
RNA category pig
Expand
RNA pig tissue group specificity
RNA pig tissue group distribution
RNA pig tissue group specificity score
RNA pig tissue group specific NX
RNA pig brain regional specificity
RNA pig brain regional distribution
RNA pig brain regional specificity score
RNA pig brain regional specific pTPM
Annotation
Expand
UMAP cluster
Within tissue variation
Pig Tissue RNA
Expand
Abdominal adipose tissue [NX]
Adrenal gland [NX]
Amygdala [NX]
Aorta [NX]
Bone marrow [NX]
Breast [NX]
Bronchus [NX]
Bulbourethral gland [NX]
Caudate [NX]
Cecum [NX]
Cerebellum [NX]
Cervix [NX]
Choroid plexus [NX]
Cingulate cortex [NX]
Colon [NX]
Cornea [NX]
Corpus callosum [NX]
Dorsal hippocampus [NX]
Dorsal spinal cord [NX]
Ductus deferens [NX]
Duodenum [NX]
Dura mater [NX]
Ear cartilage [NX]
Endometrium 1 [NX]
Entorhinal cortex [NX]
Epididymis [NX]
Esophagus [NX]
Facial adipose tissue [NX]
Fallopian tube [NX]
Gallbladder [NX]
Heart atrium [NX]
Heart valve [NX]
Heart wall [NX]
Hypothalamus [NX]
Ileum [NX]
Insular cortex [NX]
Jejunum [NX]
Joint cartilage [NX]
Kidney (cortex) [NX]
Kidney (medulla) [NX]
Larynx [NX]
Lens [NX]
Lip [NX]
Liver [NX]
Lung [NX]
Lymph node [NX]
Medulla [NX]
Midbrain [NX]
Motor cortex [NX]
Nasopharynx epithelium [NX]
Occipital cortex [NX]
Olfactory bulb [NX]
Olfactory epithelium [NX]
Oral mucosa [NX]
Ovary [NX]
Penis [NX]
Periaqueductal gray [NX]
Peritoneum [NX]
Pineal gland [NX]
Pituitary gland [NX]
Pleura [NX]
Pons [NX]
Prefrontal cortex [NX]
Prostate [NX]
Putamen [NX]
Rectum [NX]
Retina [NX]
Retrosplenial cortex [NX]
Salivary gland [NX]
Seminal vesicle [NX]
Septum [NX]
Skeletal muscle [NX]
Skin (back) [NX]
Skin (groin) [NX]
Smooth muscle (intestine) [NX]
Somatosensory cortex [NX]
Spleen [NX]
Stomach (lower) [NX]
Stomach (upper) [NX]
Subcutaneous adipose tissue [NX]
Subiculum [NX]
Substantia nigra [NX]
Superior colliculi [NX]
Synovial tissue [NX]
Temporal cortex [NX]
Testis [NX]
Thalamus [NX]
Thymus [NX]
Thyroid gland [NX]
Tongue [NX]
Tonsil [NX]
Trachea [NX]
Urethral gland [NX]
Urinary bladder [NX]
Vagus nerve [NX]
Ventral hippocampus [NX]
Ventral pallidum [NX]
Ventral spinal cord [NX]
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Gene
i
Gene name, if available.
Ensembl
x
Human ortholog
x
Gene description
x
RNA pig tissue group specificity
x
RNA pig tissue group distribution
x
RNA pig tissue group specific NX
x
ORAI1
ENSSSCG00000034510
ENSG00000276045
Calcium release-activated calcium channel protein 1
Low tissue specificity
Detected in all
OTULIN
ENSSSCG00000034714
ENSG00000154124
OTU deubiquitinase with linear linkage specificity
Low tissue specificity
Detected in all
PDCD1
ENSSSCG00000037319
ENSG00000188389
Programmed cell death protein 1 precursor
Tissue enhanced
Detected in some
large intestine:
11.0
lymphoid tissue:
14.8
thyroid gland:
7.5
PGM3
ENSSSCG00000004456
ENSG00000013375
Phosphoglucomutase 3
Tissue enhanced
Detected in all
male glands:
47.1
PIK3CD
ENSSSCG00000003395
ENSG00000171608
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
Tissue enhanced
Detected in all
lymphoid tissue:
41.1
stomach:
40.1
PLCG2
ENSSSCG00000002688
ENSG00000197943
Phospholipase C gamma 2
Tissue enhanced
Detected in many
cartilage:
44.5
lymphoid tissue:
44.7
PNP
ENSSSCG00000002135
ENSG00000198805
Purine nucleoside phosphorylase
Low tissue specificity
Detected in many
PRF1
ENSSSCG00000010271
ENSG00000180644
Perforin 1
Tissue enhanced
Detected in many
lymphoid tissue:
21.5
PRKCD
ENSSSCG00000023503
ENSG00000163932
Protein kinase C delta
Tissue enhanced
Detected in all
stomach:
54.1
PRKDC
ENSSSCG00000006274
ENSG00000253729
Protein kinase, DNA-activated, catalytic polypeptide
Low tissue specificity
Detected in all
PSMB8
ENSSSCG00000026951
ENSG00000204264
Proteasome subunit beta 8
Tissue enhanced
Detected in many
large intestine:
38.6
lymphoid tissue:
36.3
PSTPIP1
ENSSSCG00000001867
ENSG00000140368
Proline-serine-threonine phosphatase-interacting protein 1
Low tissue specificity
Detected in all
PTGER2
ENSSSCG00000021862
ENSG00000125384
Prostaglandin E receptor 2
Low tissue specificity
Detected in all
PTPN22
ENSSSCG00000006764
ENSG00000134242
Protein tyrosine phosphatase, non-receptor type 22
Tissue enhanced
Detected in many
large intestine:
13.3
lymphoid tissue:
29.9
PTPRC
ENSSSCG00000010908
ENSG00000081237
Protein tyrosine phosphatase, receptor type C
Tissue enhanced
Detected in many
lung:
34.8
lymphoid tissue:
98.6
upper respiratory system:
33.5
RAB27A
ENSSSCG00000004612
ENSG00000069974
Ras-related protein Rab-27A
Tissue enhanced
Detected in all
pituitary gland:
55.5
RAC2
ENSSSCG00000021944
ENSG00000128340
Rac family small GTPase 2
Tissue enhanced
Detected in many
lymphoid tissue:
60.0
stomach:
53.4
RAG1
ENSSSCG00000026145
ENSG00000166349
V(D)J recombination-activating protein 1
Tissue enriched
Detected in single
lymphoid tissue:
164.0
RAG2
ENSSSCG00000034285
ENSG00000175097
V(D)J recombination-activating protein 2
Tissue enriched
Detected in many
lymphoid tissue:
40.3
RBCK1
ENSSSCG00000007206
ENSG00000125826
RANBP2-type and C3HC4-type zinc finger containing 1
Low tissue specificity
Detected in all
RFX5
ENSSSCG00000006625
ENSG00000143390
Regulatory factor X5
Low tissue specificity
Detected in all
RFXANK
ENSSSCG00000036310
ENSG00000064490
DNA-binding protein RFXANK
Low tissue specificity
Detected in all
RFXAP
ENSSSCG00000009356
ENSG00000133111
Regulatory factor X associated protein
Low tissue specificity
Detected in all
RNASEH2A
ENSSSCG00000013737
ENSG00000104889
Ribonuclease H2 subunit A
Low tissue specificity
Detected in all
RNASEH2B
ENSSSCG00000024385
ENSG00000136104
Ribonuclease H2 subunit B
Tissue enriched
Detected in all
lymphoid tissue:
109.6
RNASEH2C
ENSSSCG00000012979
ENSG00000172922
Ribonuclease H2 subunit C
Low tissue specificity
Detected in all
RORC
ENSSSCG00000026427
ENSG00000143365
RAR related orphan receptor C
Tissue enhanced
Detected in many
liver:
41.5
lymphoid tissue:
53.4
male glands:
45.5
SAMHD1
ENSSSCG00000027806
ENSG00000101347
Deoxynucleoside triphosphate triphosphohydrolase SAMHD1
Tissue enhanced
Detected in all
male glands:
89.0
SBDS
ENSSSCG00000007732
ENSG00000126524
Ribosome maturation protein SBDS
Tissue enhanced
Detected in all
lens:
115.3
SERPING1
ENSSSCG00000013181
ENSG00000149131
Plasma protease C1 inhibitor precursor
Tissue enhanced
Detected in all
liver:
234.9
SH2D1A
ENSSSCG00000012643
ENSG00000183918
SH2 domain-containing protein 1A
Tissue enriched
Detected in all
lymphoid tissue:
73.7
SLA-DMA
ENSSSCG00000001470
ENSG00000204257
SLA-DM alpha chain precursor
Tissue enhanced
Detected in many
lymphoid tissue:
51.5
SLA-DQB1
ENSSSCG00000001457
ENSG00000179344,ENSG00000232629
SLA class II histocompatibility antigen, DQ haplotype C beta chain precursor
Tissue enhanced
Detected in many
lymphoid tissue:
129.0
SLC22A4
ENSSSCG00000014275
ENSG00000197208
Solute carrier family 22 member 4
Tissue enhanced
Detected in many
male glands:
34.2
SLC35C1
ENSSSCG00000025647
ENSG00000181830
GDP-fucose transporter 1
Tissue enhanced
Detected in all
male glands:
33.3
SPINK5
ENSSSCG00000014422
ENSG00000133710
Serine peptidase inhibitor, Kazal type 5
Tissue enhanced
Detected in some
esophagus:
19.0
mouth:
96.6
skin:
26.0
STAT1
ENSSSCG00000016057
ENSG00000115415
Signal transducer and activator of transcription 1
Low tissue specificity
Detected in all
STAT3
ENSSSCG00000017403
ENSG00000168610
Signal transducer and activator of transcription 3
Low tissue specificity
Detected in all
STAT4
ENSSSCG00000016059
ENSG00000138378
Signal transducer and activator of transcription 4
Tissue enriched
Detected in some
testis:
72.7
STAT5B
ENSSSCG00000017406
ENSG00000173757
Signal transducer and activator of transcription 5B
Low tissue specificity
Detected in all
STX11
ENSSSCG00000004125
ENSG00000135604
Syntaxin 11
Tissue enhanced
Detected in many
lung:
17.8
TAP1
ENSSSCG00000025618
ENSG00000168394
Antigen peptide transporter 1
Tissue enhanced
Detected in many
large intestine:
38.1
stomach:
49.4
TAPBP
ENSSSCG00000001507
ENSG00000231925
TAP binding protein
Low tissue specificity
Detected in all
TBX1
ENSSSCG00000037762
ENSG00000184058
T-box 1
Tissue enhanced
Detected in many
mouth:
31.0
skin:
39.2
TBX21
ENSSSCG00000017517
ENSG00000073861
T-box transcription factor TBX21
Low tissue specificity
Detected in all
TGFB1
ENSSSCG00000003017
ENSG00000105329
Transforming growth factor beta-1 precursor
Low tissue specificity
Detected in all
TGFB2
ENSSSCG00000010816
ENSG00000092969
Transforming growth factor beta 2
Tissue enhanced
Detected in all
choroid plexus:
100.6
TGFB3
ENSSSCG00000002385
ENSG00000119699
Transforming growth factor beta-3 precursor
Tissue enhanced
Detected in many
cartilage:
37.8
penis:
51.2
TLR2
ENSSSCG00000009002
ENSG00000137462
Toll-like receptor 2 precursor
Low tissue specificity
Detected in all
TMEM173
ENSSSCG00000014349
ENSG00000184584
Stimulator of interferon genes protein
Low tissue specificity
Detected in all
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