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Human disease related genes
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UMAP gene cluster
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Keyword
Chromosome
1
2
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5
6
7
8
9
10
11
12
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MT
Unmapped
X
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External id
Variability
Variable
Not variable
Tissue
Any
Adipose tissue
Brain
Cartilage
Heart
Kidney
Large intestine
Lymphoid tissue
Male glands
Mesothelial tissue
Mouth
Skin
Small intestine
Stomach 1
Upper respiratory system
Cluster
1 - Brain neurotransmission
2 - Brain neurotransmission
3 - Brain cellular structure
4 - Brain development
5 - Intracellular signalling
6 - Brain uncharacterized
7 - Retinal
8 - Neurohormonal
9 - Testis spermatogenesis
10 - Housekeeping transcription
11 - Testis uncharacterized
12 - Metabolic
13 - Testis sperm
14 - Low abundant uncharacterized
15 - Testis uncharacterized
16 - Aorta uncharacterized
17 - Cilium structure
18 - Low abundant uncharacterized
19 - Housekeeping mitochondrial
20 - Hormonal
21 - Low abundant uncharacterized
22 - Housekeeping transcription
23 - Cilium structure
24 - Low abundant uncharacterized
25 - Low abundant uncharacterized
26 - Low abundant uncharacterized
27 - Low abundant uncharacterized
28 - Housekeeping mitochondrial translation
29 - Male tissue bacterial defense
30 - Housekeeping structural
31 - Housekeeping uncharacterized
32 - Transport
33 - Lens
34 - Prostate uncharacterized
35 - Low abundant uncharacterized
36 - Receptors uncharacterized
37 - Olfactory bulb
38 - Lung and thyroid development
39 - Kidney transport
40 - Testis
41 - Low abundant uncharacterized
42 - Low abundant uncharacterized
43 - Breast uncharacterized
44 - Housekeeping
45 - Thymus uncharacterized
46 - Skeletal muscle contraction
47 - Spleen uncharacterized
48 - Low abundant uncharacterized
49 - Heart contraction
50 - Muscle contraction
51 - Liver and kidney
52 - Housekeeping
53 - Housekeeping mitochondrial
54 - Interferons
55 - Low abundant uncharacterized
56 - Low abundant uncharacterized
57 - Skin
58 - Immune cells
59 - Squamous epithelium
60 - Not detected
61 - Enzymes and secretion
62 - Squamous epithelium
63 - Small intestine
64 - Gastrointestinal
65 - Epithelium
66 - Housekeeping mRNA
67 - Gastrointestinal
68 - Housekeeping protein processing
69 - Housekeeping
70 - Housekeeping
71 - Housekeeping regulation
72 - Digestive and respiratory defense
73 - Housekeeping cell cycle
74 - Extracellular matrix
75 - Housekeeping
76 - Housekeeping regulation
77 - Housekeeping defense
78 - Lymphoid T cells
79 - Lymphoid myeloid
80 - Heart uncharacterized
81 - Vasculature and connective tissue
82 - Lymphoid B cell
83 - Not detected
84 - Epithelium transcription regulation
Tissue group
Any
Adipose tissue
Adrenal gland
Aorta
Bone marrow
Brain
Breast
Cartilage
Cervix
Choroid plexus
Cornea
Ductus deferens
Dura mater
Endometrium
Epididymis
Esophagus
Fallopian tube
Gallbladder
Heart
Kidney
Large intestine
Lens
Liver
Lung
Lymphoid tissue
Male glands
Mesothelial tissue
Mouth
Ovary
Penis
Pineal gland
Pituitary gland
Retina
Salivary gland
Skeletal muscle
Skin
Small intestine
Smooth muscle
Stomach
Synovial tissue
Testis
Thyroid gland
Upper respiratory system
Urinary bladder
Vagus nerve
Category
Tissue enriched
Group enriched
Tissue enhanced
Low tissue specificity
Not detected
Detected in all
Detected in many
Detected in some
Detected in single
Is highest expressed
Brain region
Any
Amygdala
Basal ganglia
Cerebellum
Cerebral cortex
Corpus callosum
Hippocampal formation
Hypothalamus
Midbrain
Olfactory region
Pituitary gland
Pons and medulla
Retina
Spinal cord
Thalamus
Category
Region enriched
Group enriched
Region enhanced
Low region specificity
Not detected
Detected in all
Detected in many
Detected in some
Detected in single
Is highest expressed
Column
Gene
Position
Tissue specific score
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THE PIG PROTEOME
THE PIG ATLAS
TISSUE SPECIFIC PROTEOME
UMAP GENE CLUSTERING
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218 GENES FOUND
Gene
Gene
i
Gene name, if available.
Gene synonym (Human ortholog)
Ensembl gene id
Ensembl gene id (Proteincoding human ortholog)
Gene description
Uniprot accession (Human ortholog)
Chromosome
Chromosome position
Related human disease
RNA category pig
RNA pig tissue group specificity
RNA pig tissue group distribution
RNA pig tissue group specificity score
RNA pig tissue group specific NX
RNA pig brain regional specificity
RNA pig brain regional distribution
RNA pig brain regional specificity score
RNA pig brain regional specific pTPM
Annotation
UMAP cluster
Within tissue variation
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Select data columns:
Gene
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Gene
i
Gene name, if available.
Gene synonym (Human ortholog)
Ensembl gene id
Ensembl gene id (Proteincoding human ortholog)
Gene description
Uniprot accession (Human ortholog)
Chromosome
Chromosome position
Related human disease
RNA category pig
Expand
RNA pig tissue group specificity
RNA pig tissue group distribution
RNA pig tissue group specificity score
RNA pig tissue group specific NX
RNA pig brain regional specificity
RNA pig brain regional distribution
RNA pig brain regional specificity score
RNA pig brain regional specific pTPM
Annotation
Expand
UMAP cluster
Within tissue variation
Pig Tissue RNA
Expand
Abdominal adipose tissue [NX]
Adrenal gland [NX]
Amygdala [NX]
Aorta [NX]
Bone marrow [NX]
Breast [NX]
Bronchus [NX]
Bulbourethral gland [NX]
Caudate [NX]
Cecum [NX]
Cerebellum [NX]
Cervix [NX]
Choroid plexus [NX]
Cingulate cortex [NX]
Colon [NX]
Cornea [NX]
Corpus callosum [NX]
Dorsal hippocampus [NX]
Dorsal spinal cord [NX]
Ductus deferens [NX]
Duodenum [NX]
Dura mater [NX]
Ear cartilage [NX]
Endometrium 1 [NX]
Entorhinal cortex [NX]
Epididymis [NX]
Esophagus [NX]
Facial adipose tissue [NX]
Fallopian tube [NX]
Gallbladder [NX]
Heart atrium [NX]
Heart valve [NX]
Heart wall [NX]
Hypothalamus [NX]
Ileum [NX]
Insular cortex [NX]
Jejunum [NX]
Joint cartilage [NX]
Kidney (cortex) [NX]
Kidney (medulla) [NX]
Larynx [NX]
Lens [NX]
Lip [NX]
Liver [NX]
Lung [NX]
Lymph node [NX]
Medulla [NX]
Midbrain [NX]
Motor cortex [NX]
Nasopharynx epithelium [NX]
Occipital cortex [NX]
Olfactory bulb [NX]
Olfactory epithelium [NX]
Oral mucosa [NX]
Ovary [NX]
Penis [NX]
Periaqueductal gray [NX]
Peritoneum [NX]
Pineal gland [NX]
Pituitary gland [NX]
Pleura [NX]
Pons [NX]
Prefrontal cortex [NX]
Prostate [NX]
Putamen [NX]
Rectum [NX]
Retina [NX]
Retrosplenial cortex [NX]
Salivary gland [NX]
Seminal vesicle [NX]
Septum [NX]
Skeletal muscle [NX]
Skin (back) [NX]
Skin (groin) [NX]
Smooth muscle (intestine) [NX]
Somatosensory cortex [NX]
Spleen [NX]
Stomach (lower) [NX]
Stomach (upper) [NX]
Subcutaneous adipose tissue [NX]
Subiculum [NX]
Substantia nigra [NX]
Superior colliculi [NX]
Synovial tissue [NX]
Temporal cortex [NX]
Testis [NX]
Thalamus [NX]
Thymus [NX]
Thyroid gland [NX]
Tongue [NX]
Tonsil [NX]
Trachea [NX]
Urethral gland [NX]
Urinary bladder [NX]
Vagus nerve [NX]
Ventral hippocampus [NX]
Ventral pallidum [NX]
Ventral spinal cord [NX]
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Gene
i
Gene name, if available.
Ensembl
x
Human ortholog
x
Gene description
x
RNA pig tissue group specificity
x
RNA pig tissue group distribution
x
RNA pig tissue group specific NX
x
NF2
ENSSSCG00000028707
ENSG00000186575
Neurofibromin 2
Low tissue specificity
Detected in all
NFE2L2
ENSSSCG00000015987
ENSG00000116044
Nuclear factor, erythroid 2 like 2
Low tissue specificity
Detected in all
NFKBIA
ENSSSCG00000001952
ENSG00000100906
NF-kappa-B inhibitor alpha
Low tissue specificity
Detected in all
NFKBIE
ENSSSCG00000001703
ENSG00000146232
NFKB inhibitor epsilon
Low tissue specificity
Detected in all
NKX3-1
ENSSSCG00000031924
ENSG00000167034
NK3 homeobox 1
Tissue enriched
Detected in some
male glands:
206.7
NOS2
ENSSSCG00000017755
ENSG00000007171
Nitric oxide synthase, inducible
Tissue enhanced
Detected in many
cartilage:
34.7
large intestine:
42.1
NOTCH1
ENSSSCG00000038509
ENSG00000148400
Notch 1
Low tissue specificity
Detected in all
NOTCH4
ENSSSCG00000001440
ENSG00000204301
Neurogenic locus notch homolog protein 4 precursor
Low tissue specificity
Detected in many
NPM1
ENSSSCG00000016998
ENSG00000181163
Nucleophosmin 1
Low tissue specificity
Detected in all
NR4A3
ENSSSCG00000005385
ENSG00000119508
Nuclear receptor subfamily 4 group A member 3
Tissue enhanced
Detected in many
heart:
83.4
male glands:
171.7
NSD2
ENSSSCG00000008682
ENSG00000109685
Nuclear receptor binding SET domain protein 2
Low tissue specificity
Detected in all
NTRK1
ENSSSCG00000006464
ENSG00000198400
Neurotrophic receptor tyrosine kinase 1
Tissue enriched
Detected in all
adrenal gland:
37.7
NTRK2
ENSSSCG00000010959
ENSG00000148053
Neurotrophic receptor tyrosine kinase 2
Tissue enhanced
Detected in many
brain:
63.2
cornea:
45.4
NTRK3
ENSSSCG00000005106
ENSG00000140538
Neurotrophic receptor tyrosine kinase 3
Tissue enhanced
Detected in many
brain:
32.2
ovary:
35.6
P14ARF
ENSSSCG00000005134
ENSG00000147889
P14ARF protein
Tissue enriched
Detected in many
testis:
66.5
PAX5
ENSSSCG00000036086
ENSG00000196092
Paired box 5
Tissue enhanced
Detected in some
lymphoid tissue:
69.4
upper respiratory system:
37.6
PDGFA
ENSSSCG00000007541
ENSG00000197461
Platelet derived growth factor subunit A
Low tissue specificity
Detected in all
PDGFB
ENSSSCG00000033327
ENSG00000100311
Platelet derived growth factor subunit B
Low tissue specificity
Detected in many
PDGFRA
ENSSSCG00000008841
ENSG00000134853
Platelet-derived growth factor receptor alpha precursor
Tissue enhanced
Detected in all
cartilage:
67.5
ovary:
55.7
PDGFRB
ENSSSCG00000022741
ENSG00000113721
Platelet derived growth factor receptor beta
Low tissue specificity
Detected in many
PIK3CA
ENSSSCG00000030413
ENSG00000121879
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
Low tissue specificity
Detected in all
PML
ENSSSCG00000001912
ENSG00000140464
Promyelocytic leukemia
Low tissue specificity
Detected in all
PRDM1
ENSSSCG00000004369
ENSG00000057657
PR/SET domain 1
Low tissue specificity
Detected in many
PTCH1
ENSSSCG00000027312
ENSG00000185920
Patched 1
Tissue enhanced
Detected in all
cartilage:
55.5
vagus nerve:
69.7
PTGES2
ENSSSCG00000022655
ENSG00000148334
Prostaglandin E synthase 2
Low tissue specificity
Detected in all
PTGS2
ENSSSCG00000015579
ENSG00000073756
Prostaglandin G/H synthase 2 precursor
Low tissue specificity
Detected in many
PTPN11
ENSSSCG00000030289
ENSG00000179295
Protein tyrosine phosphatase, non-receptor type 11
Low tissue specificity
Detected in all
RARB
ENSSSCG00000011212
ENSG00000077092
Retinoic acid receptor beta
Low tissue specificity
Detected in all
RASSF1
ENSSSCG00000011407
ENSG00000068028
Ras association domain family member 1
Low tissue specificity
Detected in all
RB1
ENSSSCG00000009401
ENSG00000139687
Retinoblastoma-associated protein
Low tissue specificity
Detected in all
REL
ENSSSCG00000008388
ENSG00000162924
REL proto-oncogene, NF-kB subunit
Low tissue specificity
Detected in all
RET
ENSSSCG00000010199
ENSG00000165731
Ret proto-oncogene
Tissue enriched
Detected in many
brain:
52.4
ROS1
ENSSSCG00000026978
ENSG00000047936
ROS proto-oncogene 1, receptor tyrosine kinase
Tissue enhanced
Detected in some
epididymis:
17.9
gallbladder:
16.8
lung:
8.9
small intestine:
20.7
RUNX1
ENSSSCG00000035537
ENSG00000159216
Runt-related transcription factor 1
Low tissue specificity
Detected in many
SDHB
ENSSSCG00000020926
ENSG00000117118
Succinate dehydrogenase
Tissue enhanced
Detected in all
skeletal muscle:
86.3
SETBP1
ENSSSCG00000004490
ENSG00000152217
SET binding protein 1
Low tissue specificity
Detected in all
SF3B1
ENSSSCG00000016075
ENSG00000115524
Splicing factor 3b subunit 1
Low tissue specificity
Detected in all
SHH
ENSSSCG00000016416
ENSG00000164690
Sonic hedgehog protein preproprotein
Group enriched
Detected in some
epididymis:
13.3
stomach:
31.7
urinary bladder:
33.0
SMAD2
ENSSSCG00000004505
ENSG00000175387
Mothers against decapentaplegic homolog 2
Low tissue specificity
Detected in all
SMAD4
ENSSSCG00000004524
ENSG00000141646
Mothers against decapentaplegic homolog 4
Low tissue specificity
Detected in all
SMARCB1
ENSSSCG00000010070
ENSG00000099956
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1
Low tissue specificity
Detected in all
SMARCE1
ENSSSCG00000039137
ENSG00000073584
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1
Low tissue specificity
Detected in all
SMO
ENSSSCG00000016569
ENSG00000128602
Smoothened, frizzled class receptor
Tissue enhanced
Detected in many
cartilage:
68.4
SPI1
ENSSSCG00000013237
ENSG00000066336
Transcription factor PU.1
Tissue enhanced
Detected in many
lung:
52.3
SRSF2
ENSSSCG00000036592
ENSG00000161547
Serine/arginine-rich splicing factor 2
Low tissue specificity
Detected in all
STAT3
ENSSSCG00000017403
ENSG00000168610
Signal transducer and activator of transcription 3
Low tissue specificity
Detected in all
STK11
ENSSSCG00000013429
ENSG00000118046
Serine/threonine kinase 11
Low tissue specificity
Detected in all
SUFU
ENSSSCG00000010586
ENSG00000107882
SUFU negative regulator of hedgehog signaling
Tissue enhanced
Detected in all
epididymis:
70.9
TAL1
ENSSSCG00000035847
ENSG00000162367
TAL bHLH transcription factor 1, erythroid differentiation factor
Tissue enhanced
Detected in many
mesothelial tissue:
33.6
TCF3
ENSSSCG00000013437
ENSG00000071564
Transcription factor 3
Low tissue specificity
Detected in all
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