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Human disease related genes
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UMAP gene cluster
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Chromosome
1
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8
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MT
Unmapped
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External id
Variability
Variable
Not variable
Tissue
Any
Adipose tissue
Brain
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Stomach 1
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Cluster
1 - Brain neurotransmission
2 - Brain neurotransmission
3 - Brain cellular structure
4 - Brain development
5 - Intracellular signalling
6 - Brain uncharacterized
7 - Retinal
8 - Neurohormonal
9 - Testis spermatogenesis
10 - Housekeeping transcription
11 - Testis uncharacterized
12 - Metabolic
13 - Testis sperm
14 - Low abundant uncharacterized
15 - Testis uncharacterized
16 - Aorta uncharacterized
17 - Cilium structure
18 - Low abundant uncharacterized
19 - Housekeeping mitochondrial
20 - Hormonal
21 - Low abundant uncharacterized
22 - Housekeeping transcription
23 - Cilium structure
24 - Low abundant uncharacterized
25 - Low abundant uncharacterized
26 - Low abundant uncharacterized
27 - Low abundant uncharacterized
28 - Housekeeping mitochondrial translation
29 - Male tissue bacterial defense
30 - Housekeeping structural
31 - Housekeeping uncharacterized
32 - Transport
33 - Lens
34 - Prostate uncharacterized
35 - Low abundant uncharacterized
36 - Receptors uncharacterized
37 - Olfactory bulb
38 - Lung and thyroid development
39 - Kidney transport
40 - Testis
41 - Low abundant uncharacterized
42 - Low abundant uncharacterized
43 - Breast uncharacterized
44 - Housekeeping
45 - Thymus uncharacterized
46 - Skeletal muscle contraction
47 - Spleen uncharacterized
48 - Low abundant uncharacterized
49 - Heart contraction
50 - Muscle contraction
51 - Liver and kidney
52 - Housekeeping
53 - Housekeeping mitochondrial
54 - Interferons
55 - Low abundant uncharacterized
56 - Low abundant uncharacterized
57 - Skin
58 - Immune cells
59 - Squamous epithelium
60 - Not detected
61 - Enzymes and secretion
62 - Squamous epithelium
63 - Small intestine
64 - Gastrointestinal
65 - Epithelium
66 - Housekeeping mRNA
67 - Gastrointestinal
68 - Housekeeping protein processing
69 - Housekeeping
70 - Housekeeping
71 - Housekeeping regulation
72 - Digestive and respiratory defense
73 - Housekeeping cell cycle
74 - Extracellular matrix
75 - Housekeeping
76 - Housekeeping regulation
77 - Housekeeping defense
78 - Lymphoid T cells
79 - Lymphoid myeloid
80 - Heart uncharacterized
81 - Vasculature and connective tissue
82 - Lymphoid B cell
83 - Not detected
84 - Epithelium transcription regulation
Tissue group
Any
Adipose tissue
Adrenal gland
Aorta
Bone marrow
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Breast
Cartilage
Cervix
Choroid plexus
Cornea
Ductus deferens
Dura mater
Endometrium
Epididymis
Esophagus
Fallopian tube
Gallbladder
Heart
Kidney
Large intestine
Lens
Liver
Lung
Lymphoid tissue
Male glands
Mesothelial tissue
Mouth
Ovary
Penis
Pineal gland
Pituitary gland
Retina
Salivary gland
Skeletal muscle
Skin
Small intestine
Smooth muscle
Stomach
Synovial tissue
Testis
Thyroid gland
Upper respiratory system
Urinary bladder
Vagus nerve
Category
Tissue enriched
Group enriched
Tissue enhanced
Low tissue specificity
Not detected
Detected in all
Detected in many
Detected in some
Detected in single
Is highest expressed
Brain region
Any
Amygdala
Basal ganglia
Cerebellum
Cerebral cortex
Corpus callosum
Hippocampal formation
Hypothalamus
Midbrain
Olfactory region
Pituitary gland
Pons and medulla
Retina
Spinal cord
Thalamus
Category
Region enriched
Group enriched
Region enhanced
Low region specificity
Not detected
Detected in all
Detected in many
Detected in some
Detected in single
Is highest expressed
Column
Gene
Position
Tissue specific score
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THE PIG PROTEOME
THE PIG ATLAS
TISSUE SPECIFIC PROTEOME
UMAP GENE CLUSTERING
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218 GENES FOUND
Gene
Gene
i
Gene name, if available.
Gene synonym (Human ortholog)
Ensembl gene id
Ensembl gene id (Proteincoding human ortholog)
Gene description
Uniprot accession (Human ortholog)
Chromosome
Chromosome position
Related human disease
RNA category pig
RNA pig tissue group specificity
RNA pig tissue group distribution
RNA pig tissue group specificity score
RNA pig tissue group specific NX
RNA pig brain regional specificity
RNA pig brain regional distribution
RNA pig brain regional specificity score
RNA pig brain regional specific pTPM
Annotation
UMAP cluster
Within tissue variation
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1.
Select data columns:
Gene
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Gene
i
Gene name, if available.
Gene synonym (Human ortholog)
Ensembl gene id
Ensembl gene id (Proteincoding human ortholog)
Gene description
Uniprot accession (Human ortholog)
Chromosome
Chromosome position
Related human disease
RNA category pig
Expand
RNA pig tissue group specificity
RNA pig tissue group distribution
RNA pig tissue group specificity score
RNA pig tissue group specific NX
RNA pig brain regional specificity
RNA pig brain regional distribution
RNA pig brain regional specificity score
RNA pig brain regional specific pTPM
Annotation
Expand
UMAP cluster
Within tissue variation
Pig Tissue RNA
Expand
Abdominal adipose tissue [NX]
Adrenal gland [NX]
Amygdala [NX]
Aorta [NX]
Bone marrow [NX]
Breast [NX]
Bronchus [NX]
Bulbourethral gland [NX]
Caudate [NX]
Cecum [NX]
Cerebellum [NX]
Cervix [NX]
Choroid plexus [NX]
Cingulate cortex [NX]
Colon [NX]
Cornea [NX]
Corpus callosum [NX]
Dorsal hippocampus [NX]
Dorsal spinal cord [NX]
Ductus deferens [NX]
Duodenum [NX]
Dura mater [NX]
Ear cartilage [NX]
Endometrium 1 [NX]
Entorhinal cortex [NX]
Epididymis [NX]
Esophagus [NX]
Facial adipose tissue [NX]
Fallopian tube [NX]
Gallbladder [NX]
Heart atrium [NX]
Heart valve [NX]
Heart wall [NX]
Hypothalamus [NX]
Ileum [NX]
Insular cortex [NX]
Jejunum [NX]
Joint cartilage [NX]
Kidney (cortex) [NX]
Kidney (medulla) [NX]
Larynx [NX]
Lens [NX]
Lip [NX]
Liver [NX]
Lung [NX]
Lymph node [NX]
Medulla [NX]
Midbrain [NX]
Motor cortex [NX]
Nasopharynx epithelium [NX]
Occipital cortex [NX]
Olfactory bulb [NX]
Olfactory epithelium [NX]
Oral mucosa [NX]
Ovary [NX]
Penis [NX]
Periaqueductal gray [NX]
Peritoneum [NX]
Pineal gland [NX]
Pituitary gland [NX]
Pleura [NX]
Pons [NX]
Prefrontal cortex [NX]
Prostate [NX]
Putamen [NX]
Rectum [NX]
Retina [NX]
Retrosplenial cortex [NX]
Salivary gland [NX]
Seminal vesicle [NX]
Septum [NX]
Skeletal muscle [NX]
Skin (back) [NX]
Skin (groin) [NX]
Smooth muscle (intestine) [NX]
Somatosensory cortex [NX]
Spleen [NX]
Stomach (lower) [NX]
Stomach (upper) [NX]
Subcutaneous adipose tissue [NX]
Subiculum [NX]
Substantia nigra [NX]
Superior colliculi [NX]
Synovial tissue [NX]
Temporal cortex [NX]
Testis [NX]
Thalamus [NX]
Thymus [NX]
Thyroid gland [NX]
Tongue [NX]
Tonsil [NX]
Trachea [NX]
Urethral gland [NX]
Urinary bladder [NX]
Vagus nerve [NX]
Ventral hippocampus [NX]
Ventral pallidum [NX]
Ventral spinal cord [NX]
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Gene
i
Gene name, if available.
Ensembl
x
Human ortholog
x
Gene description
x
RNA pig tissue group specificity
x
RNA pig tissue group distribution
x
RNA pig tissue group specific NX
x
ABL1
ENSSSCG00000005706
ENSG00000097007
ABL proto-oncogene 1, non-receptor tyrosine kinase
Tissue enriched
Detected in all
cervix:
131.8
AKT2
ENSSSCG00000002989
ENSG00000105221
RAC-beta serine/threonine-protein kinase
Tissue enhanced
Detected in all
adipose tissue:
96.5
ALK
ENSSSCG00000008533
ENSG00000171094
ALK receptor tyrosine kinase
Tissue enhanced
Detected in some
brain:
5.5
choroid plexus:
7.7
pituitary gland:
8.0
testis:
13.0
AMER1
ENSSSCG00000012361
ENSG00000184675
APC membrane recruitment protein 1
Low tissue specificity
Detected in all
APC
ENSSSCG00000014207
ENSG00000134982
Adenomatous polyposis coli protein
Tissue enhanced
Detected in all
brain:
50.8
APC2
ENSSSCG00000023329
ENSG00000115266
Adenomatous polyposis coli protein 2
Tissue enhanced
Detected in many
brain:
23.0
AR
ENSSSCG00000012371
ENSG00000169083
Androgen receptor
Tissue enhanced
Detected in many
cervix:
42.8
ARAF
ENSSSCG00000012275
ENSG00000078061
Serine/threonine-protein kinase A-Raf
Low tissue specificity
Detected in all
AREG
ENSSSCG00000008963
ENSG00000109321
Amphiregulin precursor
Tissue enhanced
Detected in all
ovary:
33.6
ARID1A
ENSSSCG00000003559
ENSG00000117713
AT-rich interaction domain 1A
Low tissue specificity
Detected in all
ARID2
ENSSSCG00000030685
ENSG00000189079
AT-rich interaction domain 2
Low tissue specificity
Detected in all
ASXL1
ENSSSCG00000007248
ENSG00000171456
Additional sex combs like 1, transcriptional regulator
Low tissue specificity
Detected in all
ATF1
ENSSSCG00000016138
ENSG00000123268
Activating transcription factor 1
Low tissue specificity
Detected in all
ATM
ENSSSCG00000025606
ENSG00000149311
Serine-protein kinase ATM
Low tissue specificity
Detected in all
ATR
ENSSSCG00000011679
ENSG00000175054
ATR serine/threonine kinase
Low tissue specificity
Detected in all
ATRX
ENSSSCG00000012434
ENSG00000085224
ATRX, chromatin remodeler
Low tissue specificity
Detected in all
AXIN1
ENSSSCG00000023204
ENSG00000103126
Axin 1
Low tissue specificity
Detected in all
AXIN2
ENSSSCG00000017265
ENSG00000168646
Axin 2
Tissue enhanced
Detected in all
cartilage:
55.2
B2M
ENSSSCG00000004687
ENSG00000166710
Beta-2-microglobulin
Low tissue specificity
Detected in all
BAX
ENSSSCG00000003144
ENSG00000087088
BCL2 associated X, apoptosis regulator
Low tissue specificity
Detected in all
BCL6
ENSSSCG00000011810
ENSG00000113916
B-cell lymphoma 6 protein
Low tissue specificity
Detected in all
BRAF
ENSSSCG00000016494
ENSG00000157764
B-Raf proto-oncogene, serine/threonine kinase
Low tissue specificity
Detected in all
BRCA1
ENSSSCG00000022101
ENSG00000012048
BRCA1, DNA repair associated
Low tissue specificity
Detected in all
BRCA2
ENSSSCG00000029039
ENSG00000139618
BRCA2, DNA repair associated
Tissue enhanced
Detected in many
lymphoid tissue:
17.0
CADM1
ENSSSCG00000031831
ENSG00000182985
Cell adhesion molecule 1
Tissue enhanced
Detected in all
lens:
122.4
CALR
ENSSSCG00000013746
ENSG00000179218
Calreticulin
Low tissue specificity
Detected in all
CARD11
ENSSSCG00000034390
ENSG00000198286
Caspase recruitment domain family member 11
Tissue enhanced
Detected in many
heart:
26.3
lymphoid tissue:
33.3
stomach:
42.8
CASR
ENSSSCG00000011878
ENSG00000036828
Extracellular calcium-sensing receptor
Tissue enhanced
Detected in all
kidney:
24.5
pituitary gland:
23.8
CBL
ENSSSCG00000015115
ENSG00000110395
Cbl proto-oncogene
Tissue enhanced
Detected in all
lymphoid tissue:
74.6
CCDC6
ENSSSCG00000010211
ENSG00000108091
Coiled-coil domain containing 6
Tissue enhanced
Detected in all
cervix:
87.3
lens:
97.5
CCND1
ENSSSCG00000037900
ENSG00000110092
Cyclin D1
Low tissue specificity
Detected in many
CCND2
ENSSSCG00000038694
ENSG00000118971
G1/S-specific cyclin-D2
Low tissue specificity
Detected in all
CCND3
ENSSSCG00000032284
ENSG00000112576
G1/S-specific cyclin-D3
Low tissue specificity
Detected in all
CD58
ENSSSCG00000006738
ENSG00000116815
Lymphocyte function-associated antigen 3 precursor
Low tissue specificity
Detected in all
CD79A
ENSSSCG00000033684
ENSG00000105369
B-cell antigen receptor complex-associated protein alpha chain precursor
Tissue enhanced
Detected in many
lymphoid tissue:
59.2
CD79B
ENSSSCG00000017283
ENSG00000007312
B-cell antigen receptor complex-associated protein beta chain precursor
Tissue enhanced
Detected in some
lymphoid tissue:
49.6
pituitary gland:
14.0
upper respiratory system:
33.2
CDC73
ENSSSCG00000010801
ENSG00000134371
Cell division cycle 73
Low tissue specificity
Detected in all
CDH1
ENSSSCG00000025652
ENSG00000039068
Cadherin-1 precursor
Tissue enhanced
Detected in many
male glands:
78.6
CDH11
ENSSSCG00000002795
ENSG00000140937
Cadherin-11 preproprotein
Tissue enhanced
Detected in many
dura mater:
51.5
CDK4
ENSSSCG00000025092
ENSG00000135446
Cyclin-dependent kinase 4
Low tissue specificity
Detected in all
CDKN1A
ENSSSCG00000001565
ENSG00000124762
Cyclin dependent kinase inhibitor 1A
Tissue enhanced
Detected in many
choroid plexus:
88.1
CDKN1B
ENSSSCG00000037144
ENSG00000111276
Cyclin-dependent kinase inhibitor 1B
Low tissue specificity
Detected in all
CDKN2B
ENSSSCG00000034120
ENSG00000147883
Cyclin-dependent kinase 4 inhibitor B
Tissue enhanced
Detected in all
mouth:
21.6
small intestine:
20.9
CDX2
ENSSSCG00000009317
ENSG00000165556
Homeobox protein CDX-2
Group enriched
Detected in some
large intestine:
91.0
small intestine:
38.5
CEBPA
ENSSSCG00000002866
ENSG00000245848
CCAAT/enhancer binding protein alpha
Tissue enhanced
Detected in many
adipose tissue:
149.5
bone marrow:
77.5
CREBBP
ENSSSCG00000007951
ENSG00000005339
CREB binding protein
Low tissue specificity
Detected in all
CRTC1
ENSSSCG00000013915
ENSG00000105662
CREB regulated transcription coactivator 1
Tissue enhanced
Detected in all
brain:
50.3
CSF1R
ENSSSCG00000014441
ENSG00000182578
Colony stimulating factor 1 receptor
Tissue enhanced
Detected in many
lymphoid tissue:
74.4
synovial tissue:
55.6
CSF3R
ENSSSCG00000025795
ENSG00000119535
Colony stimulating factor 3 receptor
Tissue enhanced
Detected in many
dura mater:
20.7
lung:
17.6
lymphoid tissue:
21.1
CTNNB1
ENSSSCG00000011274
ENSG00000168036
Catenin beta-1
Low tissue specificity
Detected in all
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