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Human disease related genes
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UMAP gene cluster
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Biological process
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Keyword
Chromosome
1
2
3
4
5
6
7
8
9
10
11
12
13
14
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MT
Unmapped
X
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External id
Variability
Variable
Not variable
Tissue
Any
Adipose tissue
Brain
Cartilage
Heart
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Lymphoid tissue
Male glands
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Mouth
Skin
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Stomach 1
Upper respiratory system
Cluster
1 - Brain neurotransmission
2 - Brain neurotransmission
3 - Brain cellular structure
4 - Brain development
5 - Intracellular signalling
6 - Brain uncharacterized
7 - Retinal
8 - Neurohormonal
9 - Testis spermatogenesis
10 - Housekeeping transcription
11 - Testis uncharacterized
12 - Metabolic
13 - Testis sperm
14 - Low abundant uncharacterized
15 - Testis uncharacterized
16 - Aorta uncharacterized
17 - Cilium structure
18 - Low abundant uncharacterized
19 - Housekeeping mitochondrial
20 - Hormonal
21 - Low abundant uncharacterized
22 - Housekeeping transcription
23 - Cilium structure
24 - Low abundant uncharacterized
25 - Low abundant uncharacterized
26 - Low abundant uncharacterized
27 - Low abundant uncharacterized
28 - Housekeeping mitochondrial translation
29 - Male tissue bacterial defense
30 - Housekeeping structural
31 - Housekeeping uncharacterized
32 - Transport
33 - Lens
34 - Prostate uncharacterized
35 - Low abundant uncharacterized
36 - Receptors uncharacterized
37 - Olfactory bulb
38 - Lung and thyroid development
39 - Kidney transport
40 - Testis
41 - Low abundant uncharacterized
42 - Low abundant uncharacterized
43 - Breast uncharacterized
44 - Housekeeping
45 - Thymus uncharacterized
46 - Skeletal muscle contraction
47 - Spleen uncharacterized
48 - Low abundant uncharacterized
49 - Heart contraction
50 - Muscle contraction
51 - Liver and kidney
52 - Housekeeping
53 - Housekeeping mitochondrial
54 - Interferons
55 - Low abundant uncharacterized
56 - Low abundant uncharacterized
57 - Skin
58 - Immune cells
59 - Squamous epithelium
60 - Not detected
61 - Enzymes and secretion
62 - Squamous epithelium
63 - Small intestine
64 - Gastrointestinal
65 - Epithelium
66 - Housekeeping mRNA
67 - Gastrointestinal
68 - Housekeeping protein processing
69 - Housekeeping
70 - Housekeeping
71 - Housekeeping regulation
72 - Digestive and respiratory defense
73 - Housekeeping cell cycle
74 - Extracellular matrix
75 - Housekeeping
76 - Housekeeping regulation
77 - Housekeeping defense
78 - Lymphoid T cells
79 - Lymphoid myeloid
80 - Heart uncharacterized
81 - Vasculature and connective tissue
82 - Lymphoid B cell
83 - Not detected
84 - Epithelium transcription regulation
Tissue group
Any
Adipose tissue
Adrenal gland
Aorta
Bone marrow
Brain
Breast
Cartilage
Cervix
Choroid plexus
Cornea
Ductus deferens
Dura mater
Endometrium
Epididymis
Esophagus
Fallopian tube
Gallbladder
Heart
Kidney
Large intestine
Lens
Liver
Lung
Lymphoid tissue
Male glands
Mesothelial tissue
Mouth
Ovary
Penis
Pineal gland
Pituitary gland
Retina
Salivary gland
Skeletal muscle
Skin
Small intestine
Smooth muscle
Stomach
Synovial tissue
Testis
Thyroid gland
Upper respiratory system
Urinary bladder
Vagus nerve
Category
Tissue enriched
Group enriched
Tissue enhanced
Low tissue specificity
Not detected
Detected in all
Detected in many
Detected in some
Detected in single
Is highest expressed
Brain region
Any
Amygdala
Basal ganglia
Cerebellum
Cerebral cortex
Corpus callosum
Hippocampal formation
Hypothalamus
Midbrain
Olfactory region
Pituitary gland
Pons and medulla
Retina
Spinal cord
Thalamus
Category
Region enriched
Group enriched
Region enhanced
Low region specificity
Not detected
Detected in all
Detected in many
Detected in some
Detected in single
Is highest expressed
Column
Gene
Position
Tissue specific score
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THE PIG PROTEOME
THE PIG ATLAS
TISSUE SPECIFIC PROTEOME
UMAP GENE CLUSTERING
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765 GENES FOUND
Gene
Gene
i
Gene name, if available.
Gene synonym (Human ortholog)
Ensembl gene id
Ensembl gene id (Proteincoding human ortholog)
Gene description
Uniprot accession (Human ortholog)
Chromosome
Chromosome position
Related human disease
RNA category pig
RNA pig tissue group specificity
RNA pig tissue group distribution
RNA pig tissue group specificity score
RNA pig tissue group specific NX
RNA pig brain regional specificity
RNA pig brain regional distribution
RNA pig brain regional specificity score
RNA pig brain regional specific pTPM
Annotation
UMAP cluster
Within tissue variation
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1.
Select data columns:
Gene
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Gene
i
Gene name, if available.
Gene synonym (Human ortholog)
Ensembl gene id
Ensembl gene id (Proteincoding human ortholog)
Gene description
Uniprot accession (Human ortholog)
Chromosome
Chromosome position
Related human disease
RNA category pig
Expand
RNA pig tissue group specificity
RNA pig tissue group distribution
RNA pig tissue group specificity score
RNA pig tissue group specific NX
RNA pig brain regional specificity
RNA pig brain regional distribution
RNA pig brain regional specificity score
RNA pig brain regional specific pTPM
Annotation
Expand
UMAP cluster
Within tissue variation
Pig Tissue RNA
Expand
Abdominal adipose tissue [NX]
Adrenal gland [NX]
Amygdala [NX]
Aorta [NX]
Bone marrow [NX]
Breast [NX]
Bronchus [NX]
Bulbourethral gland [NX]
Caudate [NX]
Cecum [NX]
Cerebellum [NX]
Cervix [NX]
Choroid plexus [NX]
Cingulate cortex [NX]
Colon [NX]
Cornea [NX]
Corpus callosum [NX]
Dorsal hippocampus [NX]
Dorsal spinal cord [NX]
Ductus deferens [NX]
Duodenum [NX]
Dura mater [NX]
Ear cartilage [NX]
Endometrium 1 [NX]
Entorhinal cortex [NX]
Epididymis [NX]
Esophagus [NX]
Facial adipose tissue [NX]
Fallopian tube [NX]
Gallbladder [NX]
Heart atrium [NX]
Heart valve [NX]
Heart wall [NX]
Hypothalamus [NX]
Ileum [NX]
Insular cortex [NX]
Jejunum [NX]
Joint cartilage [NX]
Kidney (cortex) [NX]
Kidney (medulla) [NX]
Larynx [NX]
Lens [NX]
Lip [NX]
Liver [NX]
Lung [NX]
Lymph node [NX]
Medulla [NX]
Midbrain [NX]
Motor cortex [NX]
Nasopharynx epithelium [NX]
Occipital cortex [NX]
Olfactory bulb [NX]
Olfactory epithelium [NX]
Oral mucosa [NX]
Ovary [NX]
Penis [NX]
Periaqueductal gray [NX]
Peritoneum [NX]
Pineal gland [NX]
Pituitary gland [NX]
Pleura [NX]
Pons [NX]
Prefrontal cortex [NX]
Prostate [NX]
Putamen [NX]
Rectum [NX]
Retina [NX]
Retrosplenial cortex [NX]
Salivary gland [NX]
Seminal vesicle [NX]
Septum [NX]
Skeletal muscle [NX]
Skin (back) [NX]
Skin (groin) [NX]
Smooth muscle (intestine) [NX]
Somatosensory cortex [NX]
Spleen [NX]
Stomach (lower) [NX]
Stomach (upper) [NX]
Subcutaneous adipose tissue [NX]
Subiculum [NX]
Substantia nigra [NX]
Superior colliculi [NX]
Synovial tissue [NX]
Temporal cortex [NX]
Testis [NX]
Thalamus [NX]
Thymus [NX]
Thyroid gland [NX]
Tongue [NX]
Tonsil [NX]
Trachea [NX]
Urethral gland [NX]
Urinary bladder [NX]
Vagus nerve [NX]
Ventral hippocampus [NX]
Ventral pallidum [NX]
Ventral spinal cord [NX]
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Gene
i
Gene name, if available.
Ensembl
x
Human ortholog
x
Gene description
x
RNA pig tissue group specificity
x
RNA pig tissue group distribution
x
RNA pig tissue group specific NX
x
H2AFZ
ENSSSCG00000009178
Histone H2A.Z
Tissue enhanced
Detected in all
male glands:
42.6
HEATR6
ENSSSCG00000038478
ENSG00000068097
HEAT repeat containing 6
Tissue enhanced
Detected in all
salivary gland:
81.5
HEY2
ENSSSCG00000004223
ENSG00000135547
Hairy/enhancer-of-split related with YRPW motif protein 2
Tissue enhanced
Detected in many
heart:
20.6
penis:
24.7
HHEX
ENSSSCG00000036314
ENSG00000152804
Hematopoietically-expressed homeobox protein HHEX
Tissue enhanced
Detected in many
thyroid gland:
19.5
HHIPL2
ENSSSCG00000010832
ENSG00000143512
HHIP like 2
Group enriched
Detected in many
cartilage:
71.0
synovial tissue:
27.8
HIF3A
ENSSSCG00000003101
ENSG00000124440
Hypoxia inducible factor 3 alpha subunit
Tissue enhanced
Detected in many
breast:
38.6
heart:
44.0
HIST1H2AJ
ENSSSCG00000032609
ENSG00000276368
Histone cluster 1 H2A family member j
Tissue enhanced
Detected in many
lymphoid tissue:
104.2
upper respiratory system:
68.0
HIST1H2BB
ENSSSCG00000031122
ENSG00000276410
Histone cluster 1 H2B family member b
Tissue enhanced
Detected in all
lymphoid tissue:
131.4
HIST1H2BN
ENSSSCG00000040923
ENSG00000233822
Histone cluster 1 H2B family member n
Tissue enhanced
Detected in many
lymphoid tissue:
119.5
upper respiratory system:
51.8
HIST1H3E
ENSSSCG00000039112
ENSG00000278272
Histone H3.1
Tissue enhanced
Detected in many
lymphoid tissue:
96.8
upper respiratory system:
67.8
HIST2H2AB
ENSSSCG00000037533
ENSG00000184270
Histone cluster 2 H2A family member b
Tissue enhanced
Detected in all
lymphoid tissue:
59.4
HIST3H2A
ENSSSCG00000040622
ENSG00000181218
Histone cluster 3 H2A
Tissue enhanced
Detected in many
brain:
23.1
pituitary gland:
23.2
HMCES
ENSSSCG00000011611
ENSG00000183624
5-hydroxymethylcytosine binding, ES cell specific
Tissue enhanced
Detected in all
lymphoid tissue:
62.7
HMGB2
ENSSSCG00000009704
ENSG00000164104
High mobility group protein B2
Tissue enhanced
Detected in all
lymphoid tissue:
86.5
HNF1B
ENSSSCG00000022417
ENSG00000275410
Hepatocyte nuclear factor 1-beta
Tissue enhanced
Detected in many
gallbladder:
24.5
kidney:
75.6
HOXA1
ENSSSCG00000016707
ENSG00000105991
Homeobox A1
Tissue enhanced
Detected in many
upper respiratory system:
18.7
HOXA2
ENSSSCG00000016706
ENSG00000105996
Homeobox A2
Tissue enhanced
Detected in many
male glands:
21.9
HOXA3
ENSSSCG00000016705
ENSG00000105997
Homeobox A3
Low tissue specificity
Detected in many
HOXA4
ENSSSCG00000016704
ENSG00000197576
Homeobox A4
Tissue enhanced
Detected in many
male glands:
28.6
HOXB2
ENSSSCG00000017533
ENSG00000173917
Homeobox B2
Tissue enhanced
Detected in many
male glands:
48.0
HOXB3
ENSSSCG00000017534
ENSG00000120093
Homeobox B3
Tissue enhanced
Detected in many
male glands:
64.2
HOXB4
ENSSSCG00000017535
ENSG00000182742
Homeobox B4
Tissue enhanced
Detected in many
epididymis:
47.8
male glands:
83.5
HOXB6
ENSSSCG00000017539
ENSG00000108511
Homeobox B6
Group enriched
Detected in many
epididymis:
55.3
male glands:
186.0
HOXD9
ENSSSCG00000015982
ENSG00000128709
Homeobox D9
Tissue enhanced
Detected in many
cartilage:
40.7
epididymis:
30.9
kidney:
34.1
male glands:
31.3
HRASLS
ENSSSCG00000036094
ENSG00000127252
HRAS like suppressor
Low tissue specificity
Detected in all
HRCT1
ENSSSCG00000035720
ENSG00000196196
Histidine rich carboxyl terminus 1
Tissue enhanced
Detected in many
penis:
46.2
HSD11B2
ENSSSCG00000002777
ENSG00000176387
Corticosteroid 11-beta-dehydrogenase isozyme 2
Group enriched
Detected in many
adrenal gland:
19.3
kidney:
52.6
large intestine:
68.6
salivary gland:
18.1
urinary bladder:
36.6
HSPB6
ENSSSCG00000023498
ENSG00000004776
Heat shock protein family B (small) member 6
Tissue enhanced
Detected in many
skeletal muscle:
207.1
smooth muscle:
238.3
HSPB7
ENSSSCG00000037457
ENSG00000173641
Heat shock protein beta-7
Group enriched
Detected in many
heart:
170.0
skeletal muscle:
72.9
HSPH1
ENSSSCG00000009334
ENSG00000120694
Heat shock protein 105 kDa
Tissue enhanced
Detected in all
brain:
54.3
HTRA3
ENSSSCG00000008723
ENSG00000170801
Serine protease HTRA3 precursor
Tissue enhanced
Detected in many
lens:
46.6
mesothelial tissue:
88.8
HTRA4
ENSSSCG00000015810
ENSG00000169495
HtrA serine peptidase 4
Group enriched
Detected in many
cartilage:
44.7
lymphoid tissue:
22.2
synovial tissue:
57.7
HVCN1
ENSSSCG00000009827
ENSG00000122986
Hydrogen voltage gated channel 1
Group enriched
Detected in many
choroid plexus:
88.8
lymphoid tissue:
24.2
IAPP
ENSSSCG00000000582
ENSG00000121351
Islet amyloid polypeptide
Tissue enhanced
Detected in many
brain:
42.4
choroid plexus:
21.5
upper respiratory system:
20.5
IBSP
ENSSSCG00000009219
ENSG00000029559
Integrin binding sialoprotein
Group enriched
Detected in some
bone marrow:
43.8
cartilage:
19.9
dura mater:
44.2
ovary:
57.5
ICAM3
ENSSSCG00000013649
ENSG00000076662
Intercellular adhesion molecule 3 precursor
Tissue enhanced
Detected in many
dura mater:
9.3
lung:
8.6
lymphoid tissue:
21.6
ICOS
ENSSSCG00000025042
ENSG00000163600
Tissue enhanced
Detected in some
large intestine:
7.4
lymphoid tissue:
24.6
stomach:
7.7
upper respiratory system:
7.3
IFI30
ENSSSCG00000013901
ENSG00000216490
Gamma-interferon-inducible-lysosomal thiol reductase
Tissue enhanced
Detected in many
lymphoid tissue:
50.2
ovary:
51.3
IGFBP2
ENSSSCG00000035392
ENSG00000115457
Insulin-like growth factor-binding protein 2
Tissue enhanced
Detected in many
choroid plexus:
61.1
cornea:
73.1
liver:
114.0
IGSF11
ENSSSCG00000011906
ENSG00000144847
Immunoglobulin superfamily member 11
Tissue enhanced
Detected in many
brain:
36.0
retina:
13.2
vagus nerve:
14.8
IGSF9B
ENSSSCG00000015255
ENSG00000080854
Immunoglobulin superfamily member 9B
Tissue enhanced
Detected in many
brain:
28.1
cervix:
26.6
IKZF3
ENSSSCG00000017494
ENSG00000161405
IKAROS family zinc finger 3
Tissue enhanced
Detected in many
lung:
19.1
lymphoid tissue:
49.4
small intestine:
20.5
stomach:
22.2
upper respiratory system:
27.0
IL21R
ENSSSCG00000007816
ENSG00000103522
Interleukin 21 receptor
Tissue enhanced
Detected in many
lymphoid tissue:
30.9
INMT
ENSSSCG00000016676
Indolethylamine N-methyltransferase
Tissue enriched
Detected in many
liver:
77.9
INPP5D
ENSSSCG00000016298
ENSG00000168918
Inositol polyphosphate-5-phosphatase D
Tissue enhanced
Detected in many
lymphoid tissue:
54.2
IRS4
ENSSSCG00000031027
ENSG00000133124
Insulin receptor substrate 4
Group enriched
Detected in some
brain:
18.6
choroid plexus:
55.2
pituitary gland:
62.6
IRX1
ENSSSCG00000034884
ENSG00000170549
Iroquois homeobox 1
Tissue enhanced
Detected in many
breast:
42.9
esophagus:
28.4
salivary gland:
50.8
skin:
34.9
IRX2
ENSSSCG00000032074
ENSG00000170561
Iroquois homeobox 2
Tissue enhanced
Detected in many
breast:
24.7
salivary gland:
26.6
ITGA8
ENSSSCG00000011046
ENSG00000077943
Integrin subunit alpha 8
Tissue enhanced
Detected in many
cervix:
61.7
endometrium:
34.7
fallopian tube:
40.9
KCNN4
ENSSSCG00000003069
ENSG00000104783
Intermediate conductance calcium-activated potassium channel protein 4
Tissue enhanced
Detected in some
esophagus:
17.7
male glands:
41.4
salivary gland:
35.3
upper respiratory system:
24.5
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