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Human disease related genes
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UMAP gene cluster
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Subclass
Class
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Keyword
Chromosome
1
2
3
4
5
6
7
8
9
10
11
12
13
14
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MT
Unmapped
X
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External id
Variability
Variable
Not variable
Tissue
Any
Adipose tissue
Brain
Cartilage
Heart
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Lymphoid tissue
Male glands
Mesothelial tissue
Mouth
Skin
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Stomach 1
Upper respiratory system
Cluster
1 - Brain neurotransmission
2 - Brain neurotransmission
3 - Brain cellular structure
4 - Brain development
5 - Intracellular signalling
6 - Brain uncharacterized
7 - Retinal
8 - Neurohormonal
9 - Testis spermatogenesis
10 - Housekeeping transcription
11 - Testis uncharacterized
12 - Metabolic
13 - Testis sperm
14 - Low abundant uncharacterized
15 - Testis uncharacterized
16 - Aorta uncharacterized
17 - Cilium structure
18 - Low abundant uncharacterized
19 - Housekeeping mitochondrial
20 - Hormonal
21 - Low abundant uncharacterized
22 - Housekeeping transcription
23 - Cilium structure
24 - Low abundant uncharacterized
25 - Low abundant uncharacterized
26 - Low abundant uncharacterized
27 - Low abundant uncharacterized
28 - Housekeeping mitochondrial translation
29 - Male tissue bacterial defense
30 - Housekeeping structural
31 - Housekeeping uncharacterized
32 - Transport
33 - Lens
34 - Prostate uncharacterized
35 - Low abundant uncharacterized
36 - Receptors uncharacterized
37 - Olfactory bulb
38 - Lung and thyroid development
39 - Kidney transport
40 - Testis
41 - Low abundant uncharacterized
42 - Low abundant uncharacterized
43 - Breast uncharacterized
44 - Housekeeping
45 - Thymus uncharacterized
46 - Skeletal muscle contraction
47 - Spleen uncharacterized
48 - Low abundant uncharacterized
49 - Heart contraction
50 - Muscle contraction
51 - Liver and kidney
52 - Housekeeping
53 - Housekeeping mitochondrial
54 - Interferons
55 - Low abundant uncharacterized
56 - Low abundant uncharacterized
57 - Skin
58 - Immune cells
59 - Squamous epithelium
60 - Not detected
61 - Enzymes and secretion
62 - Squamous epithelium
63 - Small intestine
64 - Gastrointestinal
65 - Epithelium
66 - Housekeeping mRNA
67 - Gastrointestinal
68 - Housekeeping protein processing
69 - Housekeeping
70 - Housekeeping
71 - Housekeeping regulation
72 - Digestive and respiratory defense
73 - Housekeeping cell cycle
74 - Extracellular matrix
75 - Housekeeping
76 - Housekeeping regulation
77 - Housekeeping defense
78 - Lymphoid T cells
79 - Lymphoid myeloid
80 - Heart uncharacterized
81 - Vasculature and connective tissue
82 - Lymphoid B cell
83 - Not detected
84 - Epithelium transcription regulation
Tissue group
Any
Adipose tissue
Adrenal gland
Aorta
Bone marrow
Brain
Breast
Cartilage
Cervix
Choroid plexus
Cornea
Ductus deferens
Dura mater
Endometrium
Epididymis
Esophagus
Fallopian tube
Gallbladder
Heart
Kidney
Large intestine
Lens
Liver
Lung
Lymphoid tissue
Male glands
Mesothelial tissue
Mouth
Ovary
Penis
Pineal gland
Pituitary gland
Retina
Salivary gland
Skeletal muscle
Skin
Small intestine
Smooth muscle
Stomach
Synovial tissue
Testis
Thyroid gland
Upper respiratory system
Urinary bladder
Vagus nerve
Category
Tissue enriched
Group enriched
Tissue enhanced
Low tissue specificity
Not detected
Detected in all
Detected in many
Detected in some
Detected in single
Is highest expressed
Brain region
Any
Amygdala
Basal ganglia
Cerebellum
Cerebral cortex
Corpus callosum
Hippocampal formation
Hypothalamus
Midbrain
Olfactory region
Pituitary gland
Pons and medulla
Retina
Spinal cord
Thalamus
Category
Region enriched
Group enriched
Region enhanced
Low region specificity
Not detected
Detected in all
Detected in many
Detected in some
Detected in single
Is highest expressed
Column
Gene
Position
Tissue specific score
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THE PIG PROTEOME
THE PIG ATLAS
TISSUE SPECIFIC PROTEOME
UMAP GENE CLUSTERING
BIOMEDICAL RESEARCH
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THE PROJECT
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916 GENES FOUND
Gene
Gene
i
Gene name, if available.
Gene synonym (Human ortholog)
Ensembl gene id
Ensembl gene id (Proteincoding human ortholog)
Gene description
Uniprot accession (Human ortholog)
Chromosome
Chromosome position
Related human disease
RNA category pig
RNA pig tissue group specificity
RNA pig tissue group distribution
RNA pig tissue group specificity score
RNA pig tissue group specific NX
RNA pig brain regional specificity
RNA pig brain regional distribution
RNA pig brain regional specificity score
RNA pig brain regional specific pTPM
Annotation
UMAP cluster
Within tissue variation
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1.
Select data columns:
Gene
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Gene
i
Gene name, if available.
Gene synonym (Human ortholog)
Ensembl gene id
Ensembl gene id (Proteincoding human ortholog)
Gene description
Uniprot accession (Human ortholog)
Chromosome
Chromosome position
Related human disease
RNA category pig
Expand
RNA pig tissue group specificity
RNA pig tissue group distribution
RNA pig tissue group specificity score
RNA pig tissue group specific NX
RNA pig brain regional specificity
RNA pig brain regional distribution
RNA pig brain regional specificity score
RNA pig brain regional specific pTPM
Annotation
Expand
UMAP cluster
Within tissue variation
Pig Tissue RNA
Expand
Abdominal adipose tissue [NX]
Adrenal gland [NX]
Amygdala [NX]
Aorta [NX]
Bone marrow [NX]
Breast [NX]
Bronchus [NX]
Bulbourethral gland [NX]
Caudate [NX]
Cecum [NX]
Cerebellum [NX]
Cervix [NX]
Choroid plexus [NX]
Cingulate cortex [NX]
Colon [NX]
Cornea [NX]
Corpus callosum [NX]
Dorsal hippocampus [NX]
Dorsal spinal cord [NX]
Ductus deferens [NX]
Duodenum [NX]
Dura mater [NX]
Ear cartilage [NX]
Endometrium 1 [NX]
Entorhinal cortex [NX]
Epididymis [NX]
Esophagus [NX]
Facial adipose tissue [NX]
Fallopian tube [NX]
Gallbladder [NX]
Heart atrium [NX]
Heart valve [NX]
Heart wall [NX]
Hypothalamus [NX]
Ileum [NX]
Insular cortex [NX]
Jejunum [NX]
Joint cartilage [NX]
Kidney (cortex) [NX]
Kidney (medulla) [NX]
Larynx [NX]
Lens [NX]
Lip [NX]
Liver [NX]
Lung [NX]
Lymph node [NX]
Medulla [NX]
Midbrain [NX]
Motor cortex [NX]
Nasopharynx epithelium [NX]
Occipital cortex [NX]
Olfactory bulb [NX]
Olfactory epithelium [NX]
Oral mucosa [NX]
Ovary [NX]
Penis [NX]
Periaqueductal gray [NX]
Peritoneum [NX]
Pineal gland [NX]
Pituitary gland [NX]
Pleura [NX]
Pons [NX]
Prefrontal cortex [NX]
Prostate [NX]
Putamen [NX]
Rectum [NX]
Retina [NX]
Retrosplenial cortex [NX]
Salivary gland [NX]
Seminal vesicle [NX]
Septum [NX]
Skeletal muscle [NX]
Skin (back) [NX]
Skin (groin) [NX]
Smooth muscle (intestine) [NX]
Somatosensory cortex [NX]
Spleen [NX]
Stomach (lower) [NX]
Stomach (upper) [NX]
Subcutaneous adipose tissue [NX]
Subiculum [NX]
Substantia nigra [NX]
Superior colliculi [NX]
Synovial tissue [NX]
Temporal cortex [NX]
Testis [NX]
Thalamus [NX]
Thymus [NX]
Thyroid gland [NX]
Tongue [NX]
Tonsil [NX]
Trachea [NX]
Urethral gland [NX]
Urinary bladder [NX]
Vagus nerve [NX]
Ventral hippocampus [NX]
Ventral pallidum [NX]
Ventral spinal cord [NX]
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Gene
i
Gene name, if available.
Ensembl
x
Human ortholog
x
Gene description
x
RNA pig tissue group specificity
x
RNA pig tissue group distribution
x
RNA pig tissue group specific NX
x
A1CF
ENSSSCG00000010431
ENSG00000148584
APOBEC1 complementation factor
Tissue enriched
Detected in some
liver:
99.7
A2M
ENSSSCG00000000660
ENSG00000175899
Alpha-2-macroglobulin
Tissue enhanced
Detected in many
adrenal gland:
238.9
liver:
109.4
testis:
79.2
ABAT
ENSSSCG00000007909
ENSG00000183044
4-aminobutyrate aminotransferase, mitochondrial
Tissue enhanced
Detected in many
brain:
48.0
kidney:
43.5
liver:
29.0
ABCC2
ENSSSCG00000010543
ENSG00000023839
ATP binding cassette subfamily C member 2
Group enriched
Detected in some
kidney:
33.8
liver:
71.6
ABCC6
ENSSSCG00000007873
ENSG00000091262
ATP binding cassette subfamily C member 6
Tissue enriched
Detected in some
liver:
71.9
ABHD15
ENSSSCG00000017789
ENSG00000168792
Abhydrolase domain containing 15
Tissue enhanced
Detected in many
adipose tissue:
25.8
ABLIM3
ENSSSCG00000014430
ENSG00000173210
Actin binding LIM protein family member 3
Tissue enhanced
Detected in many
brain:
53.4
ACAA1
ENSSSCG00000011250
ENSG00000060971
Acetyl-CoA acyltransferase 1
Tissue enhanced
Detected in all
adipose tissue:
72.9
liver:
58.5
ACE
ENSSSCG00000017296
ENSG00000159640
Angiotensin-converting enzyme isoform 1 precursor
Tissue enhanced
Detected in many
testis:
102.1
ACE2
ENSSSCG00000012138
ENSG00000130234
Angiotensin-converting enzyme 2 precursor
Group enriched
Detected in some
adipose tissue:
37.4
aorta:
16.8
kidney:
31.1
small intestine:
50.4
ACOXL
ENSSSCG00000037846
ENSG00000153093
Acyl-CoA oxidase like
Group enriched
Detected in some
ductus deferens:
15.1
epididymis:
36.6
kidney:
18.8
ACSM3
ENSSSCG00000007857
ENSG00000005187
Acyl-CoA synthetase medium chain family member 3
Tissue enhanced
Detected in many
fallopian tube:
50.3
liver:
26.6
ACSM4
ENSSSCG00000030033
ENSG00000215009
Acyl-CoA synthetase medium-chain family member 4
Tissue enriched
Detected in some
liver:
189.4
ACTC1
ENSSSCG00000004803
ENSG00000159251
Actin, alpha cardiac muscle 1
Tissue enriched
Detected in some
heart:
271.3
ADAM22
ENSSSCG00000015297
ENSG00000008277
ADAM metallopeptidase domain 22
Tissue enriched
Detected in many
brain:
51.4
ADGRL3
ENSSSCG00000026129
ENSG00000150471
Adhesion G protein-coupled receptor L3
Tissue enhanced
Detected in many
brain:
28.5
pineal gland:
20.4
ADHFE1
ENSSSCG00000006213
ENSG00000147576
Alcohol dehydrogenase, iron containing 1
Tissue enhanced
Detected in all
kidney:
35.5
ADM
ENSSSCG00000013408
ENSG00000148926
ADM Adrenomedullin Proadrenomedullin N-20 terminal peptide
Tissue enhanced
Detected in many
aorta:
30.1
cartilage:
36.0
AGFG2
ENSSSCG00000007664
ENSG00000106351
ArfGAP with FG repeats 2
Tissue enhanced
Detected in all
esophagus:
39.0
male glands:
37.6
AGMAT
ENSSSCG00000003463
ENSG00000116771
Agmatinase
Group enriched
Detected in many
kidney:
49.3
liver:
67.0
small intestine:
18.0
AGXT
ENSSSCG00000016402
ENSG00000172482
Alanine-glyoxylate aminotransferase
Group enriched
Detected in some
kidney:
67.1
liver:
90.1
AGXT2
ENSSSCG00000016829
ENSG00000113492
Alanine--glyoxylate aminotransferase 2, mitochondrial
Group enriched
Detected in all
kidney:
36.1
liver:
106.3
AHCYL2
ENSSSCG00000016568
ENSG00000158467
Adenosylhomocysteinase like 2
Tissue enhanced
Detected in all
choroid plexus:
93.8
large intestine:
59.1
AK7
ENSSSCG00000002504
ENSG00000140057
Adenylate kinase 7
Tissue enhanced
Detected in some
choroid plexus:
32.5
fallopian tube:
49.5
upper respiratory system:
26.9
AKR1B1
ENSSSCG00000040608
ENSG00000085662
Aldose reductase
Tissue enhanced
Detected in all
kidney:
55.9
lens:
113.2
male glands:
56.6
AKR1E2
ENSSSCG00000036941
ENSG00000165568
1,5-anhydro-D-fructose reductase
Tissue enriched
Detected in many
kidney:
93.3
AKR7A2
ENSSSCG00000003491
ENSG00000053371,ENSG00000162482
Aflatoxin B1 aldehyde reductase member 2
Tissue enhanced
Detected in all
kidney:
78.9
liver:
51.0
ALDH1L1
ENSSSCG00000030626
ENSG00000144908
Cytosolic 10-formyltetrahydrofolate dehydrogenase
Group enriched
Detected in many
kidney:
42.9
liver:
148.3
ALDH3A1
ENSSSCG00000018044
ENSG00000108602
Aldehyde dehydrogenase 3 family member A1
Tissue enriched
Detected in some
cornea:
707.1
ALDH3B2
ENSSSCG00000026349
ENSG00000132746
Aldehyde dehydrogenase 3 family member B2
Tissue enhanced
Detected in many
mouth:
13.0
skin:
48.0
ALDH4A1
ENSSSCG00000024752
ENSG00000159423
Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial
Tissue enhanced
Detected in all
kidney:
61.1
liver:
78.9
ALDH6A1
ENSSSCG00000002357
ENSG00000119711
Aldehyde dehydrogenase 6 family member A1
Tissue enhanced
Detected in all
kidney:
85.2
ALDH8A1
ENSSSCG00000028115
ENSG00000118514
Aldehyde dehydrogenase 8 family member A1
Group enriched
Detected in some
kidney:
47.1
liver:
82.2
ALDOB
ENSSSCG00000038300
ENSG00000136872
Aldolase, fructose-bisphosphate B
Group enriched
Detected in some
kidney:
156.9
liver:
172.6
ALPL
ENSSSCG00000032607
ENSG00000162551
Alkaline phosphatase, liver/bone/kidney
Tissue enhanced
Detected in many
dura mater:
56.0
kidney:
77.7
ALX1
ENSSSCG00000036744
ENSG00000180318
ALX homeobox 1
Tissue enhanced
Detected in many
kidney:
16.7
upper respiratory system:
8.8
AMBP
ENSSSCG00000005485
ENSG00000106927
Protein AMBP precursor
Tissue enriched
Detected in some
liver:
375.7
AMIGO2
ENSSSCG00000000810
ENSG00000139211
Adhesion molecule with Ig like domain 2
Tissue enhanced
Detected in many
ovary:
33.6
AMN
ENSSSCG00000002524
ENSG00000166126
Amnion associated transmembrane protein
Tissue enriched
Detected in some
kidney:
94.2
ANGPT2
ENSSSCG00000015753
ENSG00000091879
Angiopoietin-2 precursor
Low tissue specificity
Detected in many
ANKRD53
ENSSSCG00000031976
ENSG00000144031
Ankyrin repeat domain 53
Tissue enhanced
Detected in many
adipose tissue:
11.9
kidney:
26.0
testis:
24.9
ANKS1A
ENSSSCG00000001534
ENSG00000064999
Ankyrin repeat and SAM domain-containing protein 1A
Tissue enriched
Detected in all
kidney:
96.5
ANKS4B
ENSSSCG00000007850
ENSG00000175311
Ankyrin repeat and sterile alpha motif domain containing 4B
Tissue enhanced
Detected in some
large intestine:
27.2
liver:
35.4
male glands:
24.8
small intestine:
28.6
ANPEP
ENSSSCG00000001849
ENSG00000166825
Aminopeptidase N
Tissue enhanced
Detected in many
male glands:
57.2
small intestine:
208.3
ANXA2
ENSSSCG00000004578
ENSG00000182718
Annexin A2
Low tissue specificity
Detected in all
AOC1
ENSSSCG00000016442
ENSG00000002726
Amiloride-sensitive amine oxidase [copper-containing]
Group enriched
Detected in some
kidney:
147.9
large intestine:
49.3
small intestine:
58.7
AP1S3
ENSSSCG00000040847
ENSG00000152056
Adaptor related protein complex 1 sigma 3 subunit
Tissue enhanced
Detected in many
male glands:
31.5
APCDD1
ENSSSCG00000039797
ENSG00000154856
APC down-regulated 1
Tissue enhanced
Detected in all
epididymis:
55.5
APOA5
ENSSSCG00000015067
ENSG00000110243
Apolipoprotein A-V precursor
Tissue enriched
Detected in some
liver:
64.0
APOC3
ENSSSCG00000015069
ENSG00000110245
Apolipoprotein C-III
Tissue enriched
Detected in some
liver:
814.1
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