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Human disease related genes
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UMAP gene cluster
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Subclass
Class
Biological process
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Disease
Keyword
Chromosome
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
MT
Unmapped
X
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External id
Variability
Variable
Not variable
Tissue
Any
Adipose tissue
Brain
Cartilage
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Lymphoid tissue
Male glands
Mesothelial tissue
Mouth
Skin
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Stomach 1
Upper respiratory system
Cluster
1 - Brain neurotransmission
2 - Brain neurotransmission
3 - Brain cellular structure
4 - Brain development
5 - Intracellular signalling
6 - Brain uncharacterized
7 - Retinal
8 - Neurohormonal
9 - Testis spermatogenesis
10 - Housekeeping transcription
11 - Testis uncharacterized
12 - Metabolic
13 - Testis sperm
14 - Low abundant uncharacterized
15 - Testis uncharacterized
16 - Aorta uncharacterized
17 - Cilium structure
18 - Low abundant uncharacterized
19 - Housekeeping mitochondrial
20 - Hormonal
21 - Low abundant uncharacterized
22 - Housekeeping transcription
23 - Cilium structure
24 - Low abundant uncharacterized
25 - Low abundant uncharacterized
26 - Low abundant uncharacterized
27 - Low abundant uncharacterized
28 - Housekeeping mitochondrial translation
29 - Male tissue bacterial defense
30 - Housekeeping structural
31 - Housekeeping uncharacterized
32 - Transport
33 - Lens
34 - Prostate uncharacterized
35 - Low abundant uncharacterized
36 - Receptors uncharacterized
37 - Olfactory bulb
38 - Lung and thyroid development
39 - Kidney transport
40 - Testis
41 - Low abundant uncharacterized
42 - Low abundant uncharacterized
43 - Breast uncharacterized
44 - Housekeeping
45 - Thymus uncharacterized
46 - Skeletal muscle contraction
47 - Spleen uncharacterized
48 - Low abundant uncharacterized
49 - Heart contraction
50 - Muscle contraction
51 - Liver and kidney
52 - Housekeeping
53 - Housekeeping mitochondrial
54 - Interferons
55 - Low abundant uncharacterized
56 - Low abundant uncharacterized
57 - Skin
58 - Immune cells
59 - Squamous epithelium
60 - Not detected
61 - Enzymes and secretion
62 - Squamous epithelium
63 - Small intestine
64 - Gastrointestinal
65 - Epithelium
66 - Housekeeping mRNA
67 - Gastrointestinal
68 - Housekeeping protein processing
69 - Housekeeping
70 - Housekeeping
71 - Housekeeping regulation
72 - Digestive and respiratory defense
73 - Housekeeping cell cycle
74 - Extracellular matrix
75 - Housekeeping
76 - Housekeeping regulation
77 - Housekeeping defense
78 - Lymphoid T cells
79 - Lymphoid myeloid
80 - Heart uncharacterized
81 - Vasculature and connective tissue
82 - Lymphoid B cell
83 - Not detected
84 - Epithelium transcription regulation
Tissue group
Any
Adipose tissue
Adrenal gland
Aorta
Bone marrow
Brain
Breast
Cartilage
Cervix
Choroid plexus
Cornea
Ductus deferens
Dura mater
Endometrium
Epididymis
Esophagus
Fallopian tube
Gallbladder
Heart
Kidney
Large intestine
Lens
Liver
Lung
Lymphoid tissue
Male glands
Mesothelial tissue
Mouth
Ovary
Penis
Pineal gland
Pituitary gland
Retina
Salivary gland
Skeletal muscle
Skin
Small intestine
Smooth muscle
Stomach
Synovial tissue
Testis
Thyroid gland
Upper respiratory system
Urinary bladder
Vagus nerve
Category
Tissue enriched
Group enriched
Tissue enhanced
Low tissue specificity
Not detected
Detected in all
Detected in many
Detected in some
Detected in single
Is highest expressed
Brain region
Any
Amygdala
Basal ganglia
Cerebellum
Cerebral cortex
Corpus callosum
Hippocampal formation
Hypothalamus
Midbrain
Olfactory region
Pituitary gland
Pons and medulla
Retina
Spinal cord
Thalamus
Category
Region enriched
Group enriched
Region enhanced
Low region specificity
Not detected
Detected in all
Detected in many
Detected in some
Detected in single
Is highest expressed
Column
Gene
Position
Tissue specific score
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THE PIG PROTEOME
THE PIG ATLAS
TISSUE SPECIFIC PROTEOME
UMAP GENE CLUSTERING
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4635 GENES FOUND
Gene
Gene
i
Gene name, if available.
Gene synonym (Human ortholog)
Ensembl gene id
Ensembl gene id (Proteincoding human ortholog)
Gene description
Uniprot accession (Human ortholog)
Chromosome
Chromosome position
Related human disease
RNA category pig
RNA pig tissue group specificity
RNA pig tissue group distribution
RNA pig tissue group specificity score
RNA pig tissue group specific NX
RNA pig brain regional specificity
RNA pig brain regional distribution
RNA pig brain regional specificity score
RNA pig brain regional specific pTPM
Annotation
UMAP cluster
Within tissue variation
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1.
Select data columns:
Gene
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Gene
i
Gene name, if available.
Gene synonym (Human ortholog)
Ensembl gene id
Ensembl gene id (Proteincoding human ortholog)
Gene description
Uniprot accession (Human ortholog)
Chromosome
Chromosome position
Related human disease
RNA category pig
Expand
RNA pig tissue group specificity
RNA pig tissue group distribution
RNA pig tissue group specificity score
RNA pig tissue group specific NX
RNA pig brain regional specificity
RNA pig brain regional distribution
RNA pig brain regional specificity score
RNA pig brain regional specific pTPM
Annotation
Expand
UMAP cluster
Within tissue variation
Pig Tissue RNA
Expand
Abdominal adipose tissue [NX]
Adrenal gland [NX]
Amygdala [NX]
Aorta [NX]
Bone marrow [NX]
Breast [NX]
Bronchus [NX]
Bulbourethral gland [NX]
Caudate [NX]
Cecum [NX]
Cerebellum [NX]
Cervix [NX]
Choroid plexus [NX]
Cingulate cortex [NX]
Colon [NX]
Cornea [NX]
Corpus callosum [NX]
Dorsal hippocampus [NX]
Dorsal spinal cord [NX]
Ductus deferens [NX]
Duodenum [NX]
Dura mater [NX]
Ear cartilage [NX]
Endometrium 1 [NX]
Entorhinal cortex [NX]
Epididymis [NX]
Esophagus [NX]
Facial adipose tissue [NX]
Fallopian tube [NX]
Gallbladder [NX]
Heart atrium [NX]
Heart valve [NX]
Heart wall [NX]
Hypothalamus [NX]
Ileum [NX]
Insular cortex [NX]
Jejunum [NX]
Joint cartilage [NX]
Kidney (cortex) [NX]
Kidney (medulla) [NX]
Larynx [NX]
Lens [NX]
Lip [NX]
Liver [NX]
Lung [NX]
Lymph node [NX]
Medulla [NX]
Midbrain [NX]
Motor cortex [NX]
Nasopharynx epithelium [NX]
Occipital cortex [NX]
Olfactory bulb [NX]
Olfactory epithelium [NX]
Oral mucosa [NX]
Ovary [NX]
Penis [NX]
Periaqueductal gray [NX]
Peritoneum [NX]
Pineal gland [NX]
Pituitary gland [NX]
Pleura [NX]
Pons [NX]
Prefrontal cortex [NX]
Prostate [NX]
Putamen [NX]
Rectum [NX]
Retina [NX]
Retrosplenial cortex [NX]
Salivary gland [NX]
Seminal vesicle [NX]
Septum [NX]
Skeletal muscle [NX]
Skin (back) [NX]
Skin (groin) [NX]
Smooth muscle (intestine) [NX]
Somatosensory cortex [NX]
Spleen [NX]
Stomach (lower) [NX]
Stomach (upper) [NX]
Subcutaneous adipose tissue [NX]
Subiculum [NX]
Substantia nigra [NX]
Superior colliculi [NX]
Synovial tissue [NX]
Temporal cortex [NX]
Testis [NX]
Thalamus [NX]
Thymus [NX]
Thyroid gland [NX]
Tongue [NX]
Tonsil [NX]
Trachea [NX]
Urethral gland [NX]
Urinary bladder [NX]
Vagus nerve [NX]
Ventral hippocampus [NX]
Ventral pallidum [NX]
Ventral spinal cord [NX]
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Gene
i
Gene name, if available.
Ensembl
x
Human ortholog
x
Gene description
x
RNA pig tissue group specificity
x
RNA pig tissue group distribution
x
RNA pig tissue group specific NX
x
HOXD10
ENSSSCG00000015981
ENSG00000128710
Homeobox D10
Tissue enhanced
Detected in many
ductus deferens:
17.4
male glands:
59.0
smooth muscle:
17.7
HOXD11
ENSSSCG00000034741
ENSG00000128713
Homeobox D11
Tissue enhanced
Detected in many
male glands:
55.2
smooth muscle:
21.6
urinary bladder:
18.8
HOXD3
ENSSSCG00000015985
ENSG00000128652
Homeobox D3
Tissue enhanced
Detected in many
epididymis:
21.2
kidney:
23.0
male glands:
57.4
HOXD4
ENSSSCG00000015984
ENSG00000170166
Homeobox D4
Tissue enhanced
Detected in many
epididymis:
59.9
kidney:
38.0
male glands:
48.8
HOXD8
ENSSSCG00000040349
ENSG00000175879
Homeobox D8
Tissue enhanced
Detected in many
adrenal gland:
26.3
cartilage:
24.8
epididymis:
42.1
HOXD9
ENSSSCG00000015982
ENSG00000128709
Homeobox D9
Tissue enhanced
Detected in many
cartilage:
40.7
epididymis:
30.9
kidney:
34.1
male glands:
31.3
HPCA
ENSSSCG00000032664
ENSG00000121905
Neuron-specific calcium-binding protein hippocalcin
Tissue enriched
Detected in some
brain:
171.1
HPCAL1
ENSSSCG00000003663
ENSG00000115756
Hippocalcin-like protein 1
Tissue enhanced
Detected in all
brain:
70.4
HPCAL4
ENSSSCG00000023460
ENSG00000116983
Hippocalcin-like protein 4
Tissue enriched
Detected in some
brain:
65.9
HR
ENSSSCG00000009616
ENSG00000168453
Lysine-specific demethylase hairless
Tissue enhanced
Detected in many
mouth:
21.3
skin:
49.7
HRCT1
ENSSSCG00000035720
ENSG00000196196
Histidine rich carboxyl terminus 1
Tissue enhanced
Detected in many
penis:
46.2
HS3ST4
ENSSSCG00000039406
ENSG00000182601
Heparan sulfate-glucosamine 3-sulfotransferase 4
Tissue enriched
Detected in some
brain:
17.4
HS3ST5
ENSSSCG00000004433
ENSG00000249853
Heparan sulfate-glucosamine 3-sulfotransferase 5
Tissue enhanced
Detected in many
adrenal gland:
11.0
brain:
21.2
ductus deferens:
14.5
kidney:
13.4
HS6ST3
ENSSSCG00000009504
ENSG00000185352
Heparan sulfate 6-O-sulfotransferase 3
Tissue enhanced
Detected in many
brain:
30.3
thyroid gland:
11.0
HSBP1L1
ENSSSCG00000005778
ENSG00000226742
Heat shock factor-binding protein 1-like protein 1
Tissue enhanced
Detected in many
pineal gland:
15.3
smooth muscle:
15.4
HSCB
ENSSSCG00000034860
ENSG00000100209
HscB mitochondrial iron-sulfur cluster cochaperone
Low tissue specificity
Detected in all
HSD17B14
ENSSSCG00000003138
ENSG00000087076
Hydroxysteroid 17-beta dehydrogenase 14
Tissue enhanced
Detected in all
kidney:
90.5
liver:
62.6
HSD17B6
ENSSSCG00000027854
ENSG00000025423
Hydroxysteroid 17-beta dehydrogenase 6
Group enriched
Detected in some
brain:
22.5
liver:
82.6
male glands:
22.4
HSF4
ENSSSCG00000002792
ENSG00000102878
Heat shock transcription factor 4
Tissue enhanced
Detected in many
epididymis:
58.3
thyroid gland:
127.8
HSPA12A
ENSSSCG00000036758
ENSG00000165868
Heat shock protein family A (Hsp70) member 12A
Tissue enhanced
Detected in many
brain:
48.2
vagus nerve:
36.5
HSPA2
ENSSSCG00000002274
ENSG00000126803
Heat shock protein family A (Hsp70) member 2
Tissue enhanced
Detected in many
brain:
72.2
cornea:
50.0
testis:
72.1
vagus nerve:
68.5
HSPB1
ENSSSCG00000039962
ENSG00000106211
Heat shock protein beta-1
Low tissue specificity
Detected in all
HSPB6
ENSSSCG00000023498
ENSG00000004776
Heat shock protein family B (small) member 6
Tissue enhanced
Detected in many
skeletal muscle:
207.1
smooth muscle:
238.3
HSPB8
ENSSSCG00000009844
ENSG00000152137
Heat shock protein family B (small) member 8
Tissue enhanced
Detected in many
skeletal muscle:
123.2
HSPG2
ENSSSCG00000003514
ENSG00000142798
Heparan sulfate proteoglycan 2
Low tissue specificity
Detected in many
HSPH1
ENSSSCG00000009334
ENSG00000120694
Heat shock protein 105 kDa
Tissue enhanced
Detected in all
brain:
54.3
HTATIP2
ENSSSCG00000013349
ENSG00000109854
HIV-1 Tat interactive protein 2
Tissue enhanced
Detected in many
stomach:
73.6
HTR1A
ENSSSCG00000016940
ENSG00000178394
5-hydroxytryptamine receptor 1A
Group enriched
Detected in some
brain:
23.9
testis:
6.3
HTR1D
ENSSSCG00000025500
ENSG00000179546
5-hydroxytryptamine receptor 1D
Tissue enhanced
Detected in many
ovary:
25.9
testis:
20.4
HTR1E
ENSSSCG00000035251
ENSG00000168830
5-hydroxytryptamine receptor 1E
Tissue enhanced
Detected in some
brain:
8.3
thyroid gland:
9.6
vagus nerve:
3.8
HTR2C
ENSSSCG00000012593
ENSG00000147246
5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled
Tissue enriched
Detected in some
choroid plexus:
103.0
HTR4
ENSSSCG00000014428
ENSG00000164270
5-hydroxytryptamine receptor 4
Tissue enhanced
Detected in many
epididymis:
23.1
lens:
25.9
small intestine:
32.0
testis:
33.2
HTR6
ENSSSCG00000025244
ENSG00000158748
5-hydroxytryptamine receptor 6
Tissue enriched
Detected in many
brain:
15.1
HTR7
ENSSSCG00000010459
ENSG00000148680
5-hydroxytryptamine receptor 7
Low tissue specificity
Detected in many
HTRA3
ENSSSCG00000008723
ENSG00000170801
Serine protease HTRA3 precursor
Tissue enhanced
Detected in many
lens:
46.6
mesothelial tissue:
88.8
HUNK
ENSSSCG00000029392
ENSG00000142149
Hormonally up-regulated Neu-associated kinase
Tissue enhanced
Detected in many
cornea:
35.6
lens:
35.0
ovary:
37.7
HVCN1
ENSSSCG00000009827
ENSG00000122986
Hydrogen voltage gated channel 1
Group enriched
Detected in many
choroid plexus:
88.8
lymphoid tissue:
24.2
HYDIN
ENSSSCG00000040973
ENSG00000157423
HYDIN, axonemal central pair apparatus protein
Tissue enhanced
Detected in some
choroid plexus:
18.5
fallopian tube:
61.3
lung:
21.1
upper respiratory system:
31.1
IAPP
ENSSSCG00000000582
ENSG00000121351
Islet amyloid polypeptide
Tissue enhanced
Detected in many
brain:
42.4
choroid plexus:
21.5
upper respiratory system:
20.5
ICA1
ENSSSCG00000015346
ENSG00000003147
Islet cell autoantigen 1
Tissue enhanced
Detected in many
testis:
51.4
ICA1L
ENSSSCG00000016115
ENSG00000163596
Islet cell autoantigen 1 like
Group enriched
Detected in many
brain:
16.6
testis:
52.6
ICAM1
ENSSSCG00000013655
ENSG00000090339
Intercellular adhesion molecule 1 precursor
Tissue enhanced
Detected in many
lung:
45.5
ICAM2
ENSSSCG00000039909
ENSG00000108622
Intercellular adhesion molecule 2 precursor
Low tissue specificity
Detected in many
ID1
ENSSSCG00000037016
ENSG00000125968
DNA-binding protein inhibitor ID-1
Tissue enriched
Detected in all
brain:
58.7
ID3
ENSSSCG00000039514
ENSG00000117318
DNA-binding protein inhibitor ID-3
Low tissue specificity
Detected in all
IER2
ENSSSCG00000013753
ENSG00000160888
Immediate early response 2
Low tissue specificity
Detected in many
IER3
ENSSSCG00000027607
ENSG00000137331
Immediate early response 3
Tissue enhanced
Detected in many
cartilage:
140.2
IER5
ENSSSCG00000015541
ENSG00000162783
Immediate early response gene 5 protein
Low tissue specificity
Detected in all
IER5L
ENSSSCG00000005673
ENSG00000188483
Immediate early response 5 like
Low tissue specificity
Detected in many
IFI30
ENSSSCG00000013901
ENSG00000216490
Gamma-interferon-inducible-lysosomal thiol reductase
Tissue enhanced
Detected in many
lymphoid tissue:
50.2
ovary:
51.3
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