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Human disease related genes
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UMAP gene cluster
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Subclass
Class
Biological process
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Keyword
Chromosome
1
2
3
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5
6
7
8
9
10
11
12
13
14
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MT
Unmapped
X
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External id
Variability
Variable
Not variable
Tissue
Any
Adipose tissue
Brain
Cartilage
Heart
Kidney
Large intestine
Lymphoid tissue
Male glands
Mesothelial tissue
Mouth
Skin
Small intestine
Stomach 1
Upper respiratory system
Cluster
1 - Brain neurotransmission
2 - Brain neurotransmission
3 - Brain cellular structure
4 - Brain development
5 - Intracellular signalling
6 - Brain uncharacterized
7 - Retinal
8 - Neurohormonal
9 - Testis spermatogenesis
10 - Housekeeping transcription
11 - Testis uncharacterized
12 - Metabolic
13 - Testis sperm
14 - Low abundant uncharacterized
15 - Testis uncharacterized
16 - Aorta uncharacterized
17 - Cilium structure
18 - Low abundant uncharacterized
19 - Housekeeping mitochondrial
20 - Hormonal
21 - Low abundant uncharacterized
22 - Housekeeping transcription
23 - Cilium structure
24 - Low abundant uncharacterized
25 - Low abundant uncharacterized
26 - Low abundant uncharacterized
27 - Low abundant uncharacterized
28 - Housekeeping mitochondrial translation
29 - Male tissue bacterial defense
30 - Housekeeping structural
31 - Housekeeping uncharacterized
32 - Transport
33 - Lens
34 - Prostate uncharacterized
35 - Low abundant uncharacterized
36 - Receptors uncharacterized
37 - Olfactory bulb
38 - Lung and thyroid development
39 - Kidney transport
40 - Testis
41 - Low abundant uncharacterized
42 - Low abundant uncharacterized
43 - Breast uncharacterized
44 - Housekeeping
45 - Thymus uncharacterized
46 - Skeletal muscle contraction
47 - Spleen uncharacterized
48 - Low abundant uncharacterized
49 - Heart contraction
50 - Muscle contraction
51 - Liver and kidney
52 - Housekeeping
53 - Housekeeping mitochondrial
54 - Interferons
55 - Low abundant uncharacterized
56 - Low abundant uncharacterized
57 - Skin
58 - Immune cells
59 - Squamous epithelium
60 - Not detected
61 - Enzymes and secretion
62 - Squamous epithelium
63 - Small intestine
64 - Gastrointestinal
65 - Epithelium
66 - Housekeeping mRNA
67 - Gastrointestinal
68 - Housekeeping protein processing
69 - Housekeeping
70 - Housekeeping
71 - Housekeeping regulation
72 - Digestive and respiratory defense
73 - Housekeeping cell cycle
74 - Extracellular matrix
75 - Housekeeping
76 - Housekeeping regulation
77 - Housekeeping defense
78 - Lymphoid T cells
79 - Lymphoid myeloid
80 - Heart uncharacterized
81 - Vasculature and connective tissue
82 - Lymphoid B cell
83 - Not detected
84 - Epithelium transcription regulation
Tissue group
Any
Adipose tissue
Adrenal gland
Aorta
Bone marrow
Brain
Breast
Cartilage
Cervix
Choroid plexus
Cornea
Ductus deferens
Dura mater
Endometrium
Epididymis
Esophagus
Fallopian tube
Gallbladder
Heart
Kidney
Large intestine
Lens
Liver
Lung
Lymphoid tissue
Male glands
Mesothelial tissue
Mouth
Ovary
Penis
Pineal gland
Pituitary gland
Retina
Salivary gland
Skeletal muscle
Skin
Small intestine
Smooth muscle
Stomach
Synovial tissue
Testis
Thyroid gland
Upper respiratory system
Urinary bladder
Vagus nerve
Category
Tissue enriched
Group enriched
Tissue enhanced
Low tissue specificity
Not detected
Detected in all
Detected in many
Detected in some
Detected in single
Is highest expressed
Brain region
Any
Amygdala
Basal ganglia
Cerebellum
Cerebral cortex
Corpus callosum
Hippocampal formation
Hypothalamus
Midbrain
Olfactory region
Pituitary gland
Pons and medulla
Retina
Spinal cord
Thalamus
Category
Region enriched
Group enriched
Region enhanced
Low region specificity
Not detected
Detected in all
Detected in many
Detected in some
Detected in single
Is highest expressed
Column
Gene
Position
Tissue specific score
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14549 GENES FOUND
Gene
Gene
i
Gene name, if available.
Gene synonym (Human ortholog)
Ensembl gene id
Ensembl gene id (Proteincoding human ortholog)
Gene description
Uniprot accession (Human ortholog)
Chromosome
Chromosome position
Related human disease
RNA category pig
RNA pig tissue group specificity
RNA pig tissue group distribution
RNA pig tissue group specificity score
RNA pig tissue group specific NX
RNA pig brain regional specificity
RNA pig brain regional distribution
RNA pig brain regional specificity score
RNA pig brain regional specific pTPM
Annotation
UMAP cluster
Within tissue variation
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1.
Select data columns:
Gene
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Gene
i
Gene name, if available.
Gene synonym (Human ortholog)
Ensembl gene id
Ensembl gene id (Proteincoding human ortholog)
Gene description
Uniprot accession (Human ortholog)
Chromosome
Chromosome position
Related human disease
RNA category pig
Expand
RNA pig tissue group specificity
RNA pig tissue group distribution
RNA pig tissue group specificity score
RNA pig tissue group specific NX
RNA pig brain regional specificity
RNA pig brain regional distribution
RNA pig brain regional specificity score
RNA pig brain regional specific pTPM
Annotation
Expand
UMAP cluster
Within tissue variation
Pig Tissue RNA
Expand
Abdominal adipose tissue [NX]
Adrenal gland [NX]
Amygdala [NX]
Aorta [NX]
Bone marrow [NX]
Breast [NX]
Bronchus [NX]
Bulbourethral gland [NX]
Caudate [NX]
Cecum [NX]
Cerebellum [NX]
Cervix [NX]
Choroid plexus [NX]
Cingulate cortex [NX]
Colon [NX]
Cornea [NX]
Corpus callosum [NX]
Dorsal hippocampus [NX]
Dorsal spinal cord [NX]
Ductus deferens [NX]
Duodenum [NX]
Dura mater [NX]
Ear cartilage [NX]
Endometrium 1 [NX]
Entorhinal cortex [NX]
Epididymis [NX]
Esophagus [NX]
Facial adipose tissue [NX]
Fallopian tube [NX]
Gallbladder [NX]
Heart atrium [NX]
Heart valve [NX]
Heart wall [NX]
Hypothalamus [NX]
Ileum [NX]
Insular cortex [NX]
Jejunum [NX]
Joint cartilage [NX]
Kidney (cortex) [NX]
Kidney (medulla) [NX]
Larynx [NX]
Lens [NX]
Lip [NX]
Liver [NX]
Lung [NX]
Lymph node [NX]
Medulla [NX]
Midbrain [NX]
Motor cortex [NX]
Nasopharynx epithelium [NX]
Occipital cortex [NX]
Olfactory bulb [NX]
Olfactory epithelium [NX]
Oral mucosa [NX]
Ovary [NX]
Penis [NX]
Periaqueductal gray [NX]
Peritoneum [NX]
Pineal gland [NX]
Pituitary gland [NX]
Pleura [NX]
Pons [NX]
Prefrontal cortex [NX]
Prostate [NX]
Putamen [NX]
Rectum [NX]
Retina [NX]
Retrosplenial cortex [NX]
Salivary gland [NX]
Seminal vesicle [NX]
Septum [NX]
Skeletal muscle [NX]
Skin (back) [NX]
Skin (groin) [NX]
Smooth muscle (intestine) [NX]
Somatosensory cortex [NX]
Spleen [NX]
Stomach (lower) [NX]
Stomach (upper) [NX]
Subcutaneous adipose tissue [NX]
Subiculum [NX]
Substantia nigra [NX]
Superior colliculi [NX]
Synovial tissue [NX]
Temporal cortex [NX]
Testis [NX]
Thalamus [NX]
Thymus [NX]
Thyroid gland [NX]
Tongue [NX]
Tonsil [NX]
Trachea [NX]
Urethral gland [NX]
Urinary bladder [NX]
Vagus nerve [NX]
Ventral hippocampus [NX]
Ventral pallidum [NX]
Ventral spinal cord [NX]
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Gene
i
Gene name, if available.
Ensembl
x
Human ortholog
x
Gene description
x
RNA pig tissue group specificity
x
RNA pig tissue group distribution
x
RNA pig tissue group specific NX
x
CUX1
ENSSSCG00000007681
ENSG00000257923
Cut like homeobox 1
Low tissue specificity
Detected in all
CWC15
ENSSSCG00000014961
ENSG00000150316
CWC15 spliceosome associated protein homolog
Low tissue specificity
Detected in all
CWC22
ENSSSCG00000016008
ENSG00000163510
CWC22 spliceosome associated protein homolog
Low tissue specificity
Detected in all
CWC25
ENSSSCG00000021478
ENSG00000273559
Pre-mRNA-splicing factor CWC25 homolog
Low tissue specificity
Detected in all
CWC27
ENSSSCG00000016942
ENSG00000153015
Peptidyl-prolyl cis-trans isomerase CWC27 homolog
Low tissue specificity
Detected in all
CWF19L1
ENSSSCG00000010550
ENSG00000095485
CWF19 like 1, cell cycle control (S. pombe)
Low tissue specificity
Detected in all
CWF19L2
ENSSSCG00000028201
ENSG00000152404
CWF19-like protein 2
Low tissue specificity
Detected in all
CX3CL1
ENSSSCG00000024759
ENSG00000006210
C-X3-C motif chemokine ligand 1
Tissue enhanced
Detected in many
brain:
43.8
CXCL10
ENSSSCG00000032474
ENSG00000169245
C-X-C motif chemokine 10 precursor
Low tissue specificity
Detected in all
CXCL12
ENSSSCG00000034973
ENSG00000107562
Stromal cell-derived factor 1 precursor
Tissue enhanced
Detected in many
bone marrow:
71.3
lymphoid tissue:
82.7
CXCL14
ENSSSCG00000014310
ENSG00000145824
C-X-C motif chemokine 14 precursor
Tissue enhanced
Detected in many
skin:
100.3
stomach:
67.6
urinary bladder:
72.5
CXCL2
ENSSSCG00000008959
C-X-C motif chemokine 2 precursor
Tissue enhanced
Detected in all
adrenal gland:
51.3
CXCL9
ENSSSCG00000032777
ENSG00000138755
C-X-C motif chemokine 9 precursor
Tissue enhanced
Detected in many
large intestine:
26.7
liver:
29.3
lymphoid tissue:
41.0
CXCR3
ENSSSCG00000012402
ENSG00000186810
C-X-C motif chemokine receptor 3
Low tissue specificity
Detected in all
CXCR4
ENSSSCG00000039416
ENSG00000121966
C-X-C chemokine receptor type 4
Tissue enhanced
Detected in all
lymphoid tissue:
33.9
ovary:
25.7
CXCR5
ENSSSCG00000015098
ENSG00000160683
C-X-C motif chemokine receptor 5
Tissue enhanced
Detected in many
lymphoid tissue:
36.0
CXCR6
ENSSSCG00000011318
ENSG00000172215
C-X-C chemokine receptor type 6
Tissue enhanced
Detected in all
skeletal muscle:
30.1
CXorf36
ENSSSCG00000026984
ENSG00000147113
Chromosome X open reading frame 36
Low tissue specificity
Detected in many
CXorf38
ENSSSCG00000012249
ENSG00000185753
Chromosome X open reading frame 38
Low tissue specificity
Detected in all
CXorf56
ENSSSCG00000012622
ENSG00000018610
Chromosome X open reading frame 56
Low tissue specificity
Detected in all
CXorf57
ENSSSCG00000012549
ENSG00000147231
Chromosome X open reading frame 57
Low tissue specificity
Detected in all
CXXC1
ENSSSCG00000004517
ENSG00000154832
CXXC finger protein 1
Low tissue specificity
Detected in all
CXXC5
ENSSSCG00000037898
ENSG00000171604
CXXC finger protein 5
Low tissue specificity
Detected in all
CYB561
ENSSSCG00000017297
ENSG00000008283
Cytochrome b561
Tissue enhanced
Detected in many
adrenal gland:
75.2
ovary:
51.7
CYB561A3
ENSSSCG00000013086
ENSG00000162144
Cytochrome b561 family member A3
Low tissue specificity
Detected in all
CYB561D1
ENSSSCG00000006827
ENSG00000174151
Cytochrome b561 family member D1
Tissue enhanced
Detected in all
male glands:
43.6
CYB5A
ENSSSCG00000004875
ENSG00000166347
Cytochrome b5
Tissue enhanced
Detected in all
ovary:
184.6
testis:
159.0
CYB5B
ENSSSCG00000033944
ENSG00000103018
Cytochrome b5 type B
Tissue enriched
Detected in all
adrenal gland:
111.6
CYB5D2
ENSSSCG00000017876
ENSG00000167740
Cytochrome b5 domain containing 2
Low tissue specificity
Detected in all
CYB5R1
ENSSSCG00000010929
ENSG00000159348
Cytochrome b5 reductase 1
Tissue enhanced
Detected in all
heart:
24.6
skeletal muscle:
41.5
CYB5R3
ENSSSCG00000000038
ENSG00000100243
Cytochrome b5 reductase 3
Low tissue specificity
Detected in all
CYB5R4
ENSSSCG00000022994
ENSG00000065615
Cytochrome b5 reductase 4
Low tissue specificity
Detected in all
CYBA
ENSSSCG00000031493
ENSG00000051523
Cytochrome b-245 light chain
Low tissue specificity
Detected in all
CYBRD1
ENSSSCG00000025049
ENSG00000071967
Cytochrome b reductase 1
Low tissue specificity
Detected in all
CYC1
ENSSSCG00000031918
ENSG00000179091
Cytochrome c1
Tissue enhanced
Detected in all
heart:
112.1
skeletal muscle:
120.4
CYCS
ENSSSCG00000016714
Cytochrome c
Tissue enhanced
Detected in all
heart:
71.0
skeletal muscle:
76.2
CYGB
ENSSSCG00000017181
ENSG00000161544
Cytoglobin
Low tissue specificity
Detected in many
CYHR1
ENSSSCG00000027076
ENSG00000187954
Cysteine and histidine rich 1
Low tissue specificity
Detected in all
CYLD
ENSSSCG00000040286
ENSG00000083799
CYLD lysine 63 deubiquitinase
Low tissue specificity
Detected in all
CYP19A1
ENSSSCG00000030168
ENSG00000137869
Aromatase 1
Tissue enriched
Detected in all
testis:
249.1
CYP1A1
ENSSSCG00000001906
ENSG00000140465
Cytochrome P450 1A1
Tissue enriched
Detected in many
liver:
54.7
CYP1B1
ENSSSCG00000033844
ENSG00000138061
Cytochrome P450 family 1 subfamily B member 1
Tissue enhanced
Detected in many
dura mater:
50.8
ovary:
77.7
CYP20A1
ENSSSCG00000016118
ENSG00000119004
Cytochrome P450, family 20, subfamily A, polypeptide 1
Low tissue specificity
Detected in all
CYP21A2
ENSSSCG00000001428
ENSG00000231852
Steroid 21-hydroxylase
Tissue enriched
Detected in many
adrenal gland:
367.3
CYP24A1
ENSSSCG00000007486
ENSG00000019186
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial
Tissue enhanced
Detected in all
upper respiratory system:
29.3
CYP26C1
ENSSSCG00000010474
ENSG00000187553
Cytochrome P450 family 26 subfamily C member 1
Low tissue specificity
Detected in many
CYP27A1
ENSSSCG00000016199
ENSG00000135929
Sterol 26-hydroxylase, mitochondrial
Tissue enriched
Detected in many
liver:
139.3
CYP27B1
ENSSSCG00000028637
ENSG00000111012
25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial
Low tissue specificity
Detected in all
CYP2A19
ENSSSCG00000002993
ENSG00000197838,ENSG00000255974
Cytochrome P450 2A19
Group enriched
Detected in many
kidney:
186.8
liver:
187.0
upper respiratory system:
177.8
CYP2B22
ENSSSCG00000003006
ENSG00000197408
Cytochrome P450 2B22 precursor
Tissue enhanced
Detected in many
esophagus:
30.3
lung:
33.2
upper respiratory system:
92.8
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