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Human disease related genes
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UMAP gene cluster
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Chromosome
1
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7
8
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MT
Unmapped
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External id
Variability
Variable
Not variable
Tissue
Any
Adipose tissue
Brain
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Stomach 1
Upper respiratory system
Cluster
1 - Brain neurotransmission
2 - Brain neurotransmission
3 - Brain cellular structure
4 - Brain development
5 - Intracellular signalling
6 - Brain uncharacterized
7 - Retinal
8 - Neurohormonal
9 - Testis spermatogenesis
10 - Housekeeping transcription
11 - Testis uncharacterized
12 - Metabolic
13 - Testis sperm
14 - Low abundant uncharacterized
15 - Testis uncharacterized
16 - Aorta uncharacterized
17 - Cilium structure
18 - Low abundant uncharacterized
19 - Housekeeping mitochondrial
20 - Hormonal
21 - Low abundant uncharacterized
22 - Housekeeping transcription
23 - Cilium structure
24 - Low abundant uncharacterized
25 - Low abundant uncharacterized
26 - Low abundant uncharacterized
27 - Low abundant uncharacterized
28 - Housekeeping mitochondrial translation
29 - Male tissue bacterial defense
30 - Housekeeping structural
31 - Housekeeping uncharacterized
32 - Transport
33 - Lens
34 - Prostate uncharacterized
35 - Low abundant uncharacterized
36 - Receptors uncharacterized
37 - Olfactory bulb
38 - Lung and thyroid development
39 - Kidney transport
40 - Testis
41 - Low abundant uncharacterized
42 - Low abundant uncharacterized
43 - Breast uncharacterized
44 - Housekeeping
45 - Thymus uncharacterized
46 - Skeletal muscle contraction
47 - Spleen uncharacterized
48 - Low abundant uncharacterized
49 - Heart contraction
50 - Muscle contraction
51 - Liver and kidney
52 - Housekeeping
53 - Housekeeping mitochondrial
54 - Interferons
55 - Low abundant uncharacterized
56 - Low abundant uncharacterized
57 - Skin
58 - Immune cells
59 - Squamous epithelium
60 - Not detected
61 - Enzymes and secretion
62 - Squamous epithelium
63 - Small intestine
64 - Gastrointestinal
65 - Epithelium
66 - Housekeeping mRNA
67 - Gastrointestinal
68 - Housekeeping protein processing
69 - Housekeeping
70 - Housekeeping
71 - Housekeeping regulation
72 - Digestive and respiratory defense
73 - Housekeeping cell cycle
74 - Extracellular matrix
75 - Housekeeping
76 - Housekeeping regulation
77 - Housekeeping defense
78 - Lymphoid T cells
79 - Lymphoid myeloid
80 - Heart uncharacterized
81 - Vasculature and connective tissue
82 - Lymphoid B cell
83 - Not detected
84 - Epithelium transcription regulation
Tissue group
Any
Adipose tissue
Adrenal gland
Aorta
Bone marrow
Brain
Breast
Cartilage
Cervix
Choroid plexus
Cornea
Ductus deferens
Dura mater
Endometrium
Epididymis
Esophagus
Fallopian tube
Gallbladder
Heart
Kidney
Large intestine
Lens
Liver
Lung
Lymphoid tissue
Male glands
Mesothelial tissue
Mouth
Ovary
Penis
Pineal gland
Pituitary gland
Retina
Salivary gland
Skeletal muscle
Skin
Small intestine
Smooth muscle
Stomach
Synovial tissue
Testis
Thyroid gland
Upper respiratory system
Urinary bladder
Vagus nerve
Category
Tissue enriched
Group enriched
Tissue enhanced
Low tissue specificity
Not detected
Detected in all
Detected in many
Detected in some
Detected in single
Is highest expressed
Brain region
Any
Amygdala
Basal ganglia
Cerebellum
Cerebral cortex
Corpus callosum
Hippocampal formation
Hypothalamus
Midbrain
Olfactory region
Pituitary gland
Pons and medulla
Retina
Spinal cord
Thalamus
Category
Region enriched
Group enriched
Region enhanced
Low region specificity
Not detected
Detected in all
Detected in many
Detected in some
Detected in single
Is highest expressed
Column
Gene
Position
Tissue specific score
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THE PIG PROTEOME
THE PIG ATLAS
TISSUE SPECIFIC PROTEOME
UMAP GENE CLUSTERING
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15765 GENES FOUND
Gene
Gene
i
Gene name, if available.
Gene synonym (Human ortholog)
Ensembl gene id
Ensembl gene id (Proteincoding human ortholog)
Gene description
Uniprot accession (Human ortholog)
Chromosome
Chromosome position
Related human disease
RNA category pig
RNA pig tissue group specificity
RNA pig tissue group distribution
RNA pig tissue group specificity score
RNA pig tissue group specific NX
RNA pig brain regional specificity
RNA pig brain regional distribution
RNA pig brain regional specificity score
RNA pig brain regional specific pTPM
Annotation
UMAP cluster
Within tissue variation
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Select data columns:
Gene
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Gene
i
Gene name, if available.
Gene synonym (Human ortholog)
Ensembl gene id
Ensembl gene id (Proteincoding human ortholog)
Gene description
Uniprot accession (Human ortholog)
Chromosome
Chromosome position
Related human disease
RNA category pig
Expand
RNA pig tissue group specificity
RNA pig tissue group distribution
RNA pig tissue group specificity score
RNA pig tissue group specific NX
RNA pig brain regional specificity
RNA pig brain regional distribution
RNA pig brain regional specificity score
RNA pig brain regional specific pTPM
Annotation
Expand
UMAP cluster
Within tissue variation
Pig Tissue RNA
Expand
Abdominal adipose tissue [NX]
Adrenal gland [NX]
Amygdala [NX]
Aorta [NX]
Bone marrow [NX]
Breast [NX]
Bronchus [NX]
Bulbourethral gland [NX]
Caudate [NX]
Cecum [NX]
Cerebellum [NX]
Cervix [NX]
Choroid plexus [NX]
Cingulate cortex [NX]
Colon [NX]
Cornea [NX]
Corpus callosum [NX]
Dorsal hippocampus [NX]
Dorsal spinal cord [NX]
Ductus deferens [NX]
Duodenum [NX]
Dura mater [NX]
Ear cartilage [NX]
Endometrium 1 [NX]
Entorhinal cortex [NX]
Epididymis [NX]
Esophagus [NX]
Facial adipose tissue [NX]
Fallopian tube [NX]
Gallbladder [NX]
Heart atrium [NX]
Heart valve [NX]
Heart wall [NX]
Hypothalamus [NX]
Ileum [NX]
Insular cortex [NX]
Jejunum [NX]
Joint cartilage [NX]
Kidney (cortex) [NX]
Kidney (medulla) [NX]
Larynx [NX]
Lens [NX]
Lip [NX]
Liver [NX]
Lung [NX]
Lymph node [NX]
Medulla [NX]
Midbrain [NX]
Motor cortex [NX]
Nasopharynx epithelium [NX]
Occipital cortex [NX]
Olfactory bulb [NX]
Olfactory epithelium [NX]
Oral mucosa [NX]
Ovary [NX]
Penis [NX]
Periaqueductal gray [NX]
Peritoneum [NX]
Pineal gland [NX]
Pituitary gland [NX]
Pleura [NX]
Pons [NX]
Prefrontal cortex [NX]
Prostate [NX]
Putamen [NX]
Rectum [NX]
Retina [NX]
Retrosplenial cortex [NX]
Salivary gland [NX]
Seminal vesicle [NX]
Septum [NX]
Skeletal muscle [NX]
Skin (back) [NX]
Skin (groin) [NX]
Smooth muscle (intestine) [NX]
Somatosensory cortex [NX]
Spleen [NX]
Stomach (lower) [NX]
Stomach (upper) [NX]
Subcutaneous adipose tissue [NX]
Subiculum [NX]
Substantia nigra [NX]
Superior colliculi [NX]
Synovial tissue [NX]
Temporal cortex [NX]
Testis [NX]
Thalamus [NX]
Thymus [NX]
Thyroid gland [NX]
Tongue [NX]
Tonsil [NX]
Trachea [NX]
Urethral gland [NX]
Urinary bladder [NX]
Vagus nerve [NX]
Ventral hippocampus [NX]
Ventral pallidum [NX]
Ventral spinal cord [NX]
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Gene
i
Gene name, if available.
Ensembl
x
Human ortholog
x
Gene description
x
RNA pig tissue group specificity
x
RNA pig tissue group distribution
x
RNA pig tissue group specific NX
x
IKBKE
ENSSSCG00000015644
ENSG00000263528
Inhibitor of nuclear factor kappa B kinase subunit epsilon
Tissue enhanced
Detected in many
lymphoid tissue:
23.4
stomach:
34.5
IKBKG
ENSSSCG00000012825
ENSG00000269335
NF-kappa-B essential modulator
Low tissue specificity
Detected in all
IKZF1
ENSSSCG00000038345
ENSG00000185811
IKAROS family zinc finger 1
Tissue enhanced
Detected in many
lymphoid tissue:
58.1
stomach:
28.1
IKZF2
ENSSSCG00000016164
ENSG00000030419
IKAROS family zinc finger 2
Tissue enhanced
Detected in many
lymphoid tissue:
50.2
IKZF3
ENSSSCG00000017494
ENSG00000161405
IKAROS family zinc finger 3
Tissue enhanced
Detected in many
lung:
19.1
lymphoid tissue:
49.4
small intestine:
20.5
stomach:
22.2
upper respiratory system:
27.0
IKZF4
ENSSSCG00000031139
ENSG00000123411
IKAROS family zinc finger 4
Low tissue specificity
Detected in all
IKZF5
ENSSSCG00000023565
ENSG00000095574
IKAROS family zinc finger 5
Low tissue specificity
Detected in all
IL10
ENSSSCG00000015652
ENSG00000136634
Interleukin-10
Tissue enhanced
Detected in many
lymphoid tissue:
16.1
IL10RA
ENSSSCG00000015085
ENSG00000110324
Interleukin 10 receptor subunit alpha
Tissue enhanced
Detected in many
lymphoid tissue:
47.1
IL10RB
ENSSSCG00000036556
ENSG00000159110,ENSG00000249624
Interferon alpha/beta receptor 2
Low tissue specificity
Detected in all
IL11RA
ENSSSCG00000010968
ENSG00000137070
Interleukin 11 receptor subunit alpha
Low tissue specificity
Detected in all
IL12A
ENSSSCG00000011730
ENSG00000168811
Interleukin-12 subunit alpha
Low tissue specificity
Detected in many
IL12RB1
ENSSSCG00000013894
ENSG00000096996
Interleukin-12 receptor subunit beta-1 precursor
Tissue enhanced
Detected in all
lymphoid tissue:
25.4
IL12RB2
ENSSSCG00000003799
ENSG00000081985
Interleukin-12 receptor subunit beta-2 precursor
Tissue enhanced
Detected in all
lymphoid tissue:
38.6
IL13
ENSSSCG00000014281
ENSG00000169194
Interleukin-13
Tissue enhanced
Detected in many
testis:
6.9
IL13RA1
ENSSSCG00000012633
ENSG00000131724
Interleukin-13 receptor subunit alpha-1 precursor
Low tissue specificity
Detected in many
IL13RA2
ENSSSCG00000012594
ENSG00000123496
Interleukin-13 receptor subunit alpha-2 precursor
Tissue enhanced
Detected in many
liver:
16.9
testis:
10.6
IL15
ENSSSCG00000009051
ENSG00000164136
Interleukin-15 precursor
Tissue enhanced
Detected in many
choroid plexus:
25.5
male glands:
26.7
IL16
ENSSSCG00000001787
ENSG00000172349
Interleukin 16
Tissue enhanced
Detected in many
brain:
33.7
cartilage:
33.1
lymphoid tissue:
27.4
mesothelial tissue:
27.3
vagus nerve:
24.3
IL17B
ENSSSCG00000014434
ENSG00000127743
Interleukin 17B
Tissue enhanced
Detected in many
cartilage:
51.8
male glands:
48.2
IL17C
ENSSSCG00000040406
ENSG00000124391
Interleukin 17C
Group enriched
Detected in many
stomach:
30.5
upper respiratory system:
11.9
IL17D
ENSSSCG00000025308
ENSG00000172458
Interleukin 17D
Low tissue specificity
Detected in all
IL17F
ENSSSCG00000001749
ENSG00000112116
Interleukin 17F
Low tissue specificity
Detected in all
IL17RA
ENSSSCG00000000765
ENSG00000177663
Interleukin 17 receptor A
Low tissue specificity
Detected in all
IL17RB
ENSSSCG00000037914
ENSG00000056736
Interleukin 17 receptor B
Low tissue specificity
Detected in all
IL17RC
ENSSSCG00000011559
ENSG00000163702
Interleukin 17 receptor C
Low tissue specificity
Detected in many
IL17RD
ENSSSCG00000011463
ENSG00000144730
Interleukin 17 receptor D
Tissue enhanced
Detected in many
pituitary gland:
26.0
IL18
ENSSSCG00000015037
ENSG00000150782
Interleukin-18
Low tissue specificity
Detected in many
IL18R1
ENSSSCG00000032795
ENSG00000115604
Interleukin-18 receptor 1 precursor
Tissue enhanced
Detected in all
lymphoid tissue:
36.5
IL18RAP
ENSSSCG00000008157
ENSG00000115607
Interleukin 18 receptor accessory protein
Tissue enhanced
Detected in some
dura mater:
6.9
lymphoid tissue:
5.7
stomach:
4.3
IL1A
ENSSSCG00000008090
ENSG00000115008
Interleukin-1 alpha
Tissue enhanced
Detected in many
lung:
17.9
IL1R1
ENSSSCG00000008162
ENSG00000115594
Interleukin 1 receptor type 1
Tissue enhanced
Detected in all
liver:
74.2
IL1RAP
ENSSSCG00000021206
ENSG00000196083
Interleukin 1 receptor accessory protein
Tissue enhanced
Detected in all
liver:
31.1
IL1RL1
ENSSSCG00000008159
ENSG00000115602
Interleukin 1 receptor like 1
Group enriched
Detected in many
gallbladder:
53.2
smooth muscle:
37.6
IL2
ENSSSCG00000033267
ENSG00000109471
Interleukin-2
Low tissue specificity
Detected in all
IL20RA
ENSSSCG00000004157
ENSG00000016402
Interleukin 20 receptor subunit alpha
Tissue enhanced
Detected in all
skin:
26.5
IL20RB
ENSSSCG00000022500
ENSG00000174564
Interleukin 20 receptor subunit beta
Tissue enhanced
Detected in some
cornea:
34.2
lymphoid tissue:
53.8
skin:
17.3
IL21R
ENSSSCG00000007816
ENSG00000103522
Interleukin 21 receptor
Tissue enhanced
Detected in many
lymphoid tissue:
30.9
IL22RA1
ENSSSCG00000038848
ENSG00000142677
Interleukin 22 receptor subunit alpha 1
Tissue enhanced
Detected in some
gallbladder:
14.6
liver:
29.4
small intestine:
17.4
stomach:
17.9
IL23R
ENSSSCG00000003801
ENSG00000162594
Interleukin-23 receptor
Low tissue specificity
Detected in all
IL26
ENSSSCG00000039976
ENSG00000111536
Interleukin 26
Low tissue specificity
Detected in all
IL27RA
ENSSSCG00000013766
ENSG00000104998
Interleukin-27 receptor subunit alpha precursor
Tissue enhanced
Detected in many
lymphoid tissue:
36.5
ovary:
26.3
IL29
ENSSSCG00000036439
ENSG00000182393
Interleukin-29 precursor
Low tissue specificity
Detected in many
IL2RA
ENSSSCG00000022849
ENSG00000134460
Interleukin-2 receptor subunit alpha precursor
Tissue enhanced
Detected in many
lymphoid tissue:
23.3
IL2RB
ENSSSCG00000029668
ENSG00000100385
Interleukin 2 receptor subunit beta
Tissue enhanced
Detected in many
lymphoid tissue:
37.9
stomach:
44.7
IL31RA
ENSSSCG00000016915
ENSG00000164509
Interleukin 31 receptor A
Tissue enhanced
Detected in some
male glands:
22.8
IL33
ENSSSCG00000005203
ENSG00000137033
Interleukin-33
Low tissue specificity
Detected in many
IL34
ENSSSCG00000040629
ENSG00000157368
Interleukin-34 precursor
Tissue enhanced
Detected in many
brain:
39.4
vagus nerve:
22.3
IL4
ENSSSCG00000014282
ENSG00000113520
Interleukin-4
Tissue enhanced
Detected in many
fallopian tube:
8.5
testis:
6.5
IL4I1
ENSSSCG00000003192
ENSG00000104951
Interleukin 4 induced 1
Tissue enriched
Detected in many
testis:
91.7
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