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Human disease related genes
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UMAP gene cluster
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Keyword
Chromosome
1
2
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7
8
9
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11
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MT
Unmapped
X
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External id
Variability
Variable
Not variable
Tissue
Any
Adipose tissue
Brain
Cartilage
Heart
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Large intestine
Lymphoid tissue
Male glands
Mesothelial tissue
Mouth
Skin
Small intestine
Stomach 1
Upper respiratory system
Cluster
1 - Brain neurotransmission
2 - Brain neurotransmission
3 - Brain cellular structure
4 - Brain development
5 - Intracellular signalling
6 - Brain uncharacterized
7 - Retinal
8 - Neurohormonal
9 - Testis spermatogenesis
10 - Housekeeping transcription
11 - Testis uncharacterized
12 - Metabolic
13 - Testis sperm
14 - Low abundant uncharacterized
15 - Testis uncharacterized
16 - Aorta uncharacterized
17 - Cilium structure
18 - Low abundant uncharacterized
19 - Housekeeping mitochondrial
20 - Hormonal
21 - Low abundant uncharacterized
22 - Housekeeping transcription
23 - Cilium structure
24 - Low abundant uncharacterized
25 - Low abundant uncharacterized
26 - Low abundant uncharacterized
27 - Low abundant uncharacterized
28 - Housekeeping mitochondrial translation
29 - Male tissue bacterial defense
30 - Housekeeping structural
31 - Housekeeping uncharacterized
32 - Transport
33 - Lens
34 - Prostate uncharacterized
35 - Low abundant uncharacterized
36 - Receptors uncharacterized
37 - Olfactory bulb
38 - Lung and thyroid development
39 - Kidney transport
40 - Testis
41 - Low abundant uncharacterized
42 - Low abundant uncharacterized
43 - Breast uncharacterized
44 - Housekeeping
45 - Thymus uncharacterized
46 - Skeletal muscle contraction
47 - Spleen uncharacterized
48 - Low abundant uncharacterized
49 - Heart contraction
50 - Muscle contraction
51 - Liver and kidney
52 - Housekeeping
53 - Housekeeping mitochondrial
54 - Interferons
55 - Low abundant uncharacterized
56 - Low abundant uncharacterized
57 - Skin
58 - Immune cells
59 - Squamous epithelium
60 - Not detected
61 - Enzymes and secretion
62 - Squamous epithelium
63 - Small intestine
64 - Gastrointestinal
65 - Epithelium
66 - Housekeeping mRNA
67 - Gastrointestinal
68 - Housekeeping protein processing
69 - Housekeeping
70 - Housekeeping
71 - Housekeeping regulation
72 - Digestive and respiratory defense
73 - Housekeeping cell cycle
74 - Extracellular matrix
75 - Housekeeping
76 - Housekeeping regulation
77 - Housekeeping defense
78 - Lymphoid T cells
79 - Lymphoid myeloid
80 - Heart uncharacterized
81 - Vasculature and connective tissue
82 - Lymphoid B cell
83 - Not detected
84 - Epithelium transcription regulation
Tissue group
Any
Adipose tissue
Adrenal gland
Aorta
Bone marrow
Brain
Breast
Cartilage
Cervix
Choroid plexus
Cornea
Ductus deferens
Dura mater
Endometrium
Epididymis
Esophagus
Fallopian tube
Gallbladder
Heart
Kidney
Large intestine
Lens
Liver
Lung
Lymphoid tissue
Male glands
Mesothelial tissue
Mouth
Ovary
Penis
Pineal gland
Pituitary gland
Retina
Salivary gland
Skeletal muscle
Skin
Small intestine
Smooth muscle
Stomach
Synovial tissue
Testis
Thyroid gland
Upper respiratory system
Urinary bladder
Vagus nerve
Category
Tissue enriched
Group enriched
Tissue enhanced
Low tissue specificity
Not detected
Detected in all
Detected in many
Detected in some
Detected in single
Is highest expressed
Brain region
Any
Amygdala
Basal ganglia
Cerebellum
Cerebral cortex
Corpus callosum
Hippocampal formation
Hypothalamus
Midbrain
Olfactory region
Pituitary gland
Pons and medulla
Retina
Spinal cord
Thalamus
Category
Region enriched
Group enriched
Region enhanced
Low region specificity
Not detected
Detected in all
Detected in many
Detected in some
Detected in single
Is highest expressed
Column
Gene
Position
Tissue specific score
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15311 GENES FOUND
Gene
Gene
i
Gene name, if available.
Gene synonym (Human ortholog)
Ensembl gene id
Ensembl gene id (Proteincoding human ortholog)
Gene description
Uniprot accession (Human ortholog)
Chromosome
Chromosome position
Related human disease
RNA category pig
RNA pig tissue group specificity
RNA pig tissue group distribution
RNA pig tissue group specificity score
RNA pig tissue group specific NX
RNA pig brain regional specificity
RNA pig brain regional distribution
RNA pig brain regional specificity score
RNA pig brain regional specific pTPM
Annotation
UMAP cluster
Within tissue variation
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Select data columns:
Gene
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Gene
i
Gene name, if available.
Gene synonym (Human ortholog)
Ensembl gene id
Ensembl gene id (Proteincoding human ortholog)
Gene description
Uniprot accession (Human ortholog)
Chromosome
Chromosome position
Related human disease
RNA category pig
Expand
RNA pig tissue group specificity
RNA pig tissue group distribution
RNA pig tissue group specificity score
RNA pig tissue group specific NX
RNA pig brain regional specificity
RNA pig brain regional distribution
RNA pig brain regional specificity score
RNA pig brain regional specific pTPM
Annotation
Expand
UMAP cluster
Within tissue variation
Pig Tissue RNA
Expand
Abdominal adipose tissue [NX]
Adrenal gland [NX]
Amygdala [NX]
Aorta [NX]
Bone marrow [NX]
Breast [NX]
Bronchus [NX]
Bulbourethral gland [NX]
Caudate [NX]
Cecum [NX]
Cerebellum [NX]
Cervix [NX]
Choroid plexus [NX]
Cingulate cortex [NX]
Colon [NX]
Cornea [NX]
Corpus callosum [NX]
Dorsal hippocampus [NX]
Dorsal spinal cord [NX]
Ductus deferens [NX]
Duodenum [NX]
Dura mater [NX]
Ear cartilage [NX]
Endometrium 1 [NX]
Entorhinal cortex [NX]
Epididymis [NX]
Esophagus [NX]
Facial adipose tissue [NX]
Fallopian tube [NX]
Gallbladder [NX]
Heart atrium [NX]
Heart valve [NX]
Heart wall [NX]
Hypothalamus [NX]
Ileum [NX]
Insular cortex [NX]
Jejunum [NX]
Joint cartilage [NX]
Kidney (cortex) [NX]
Kidney (medulla) [NX]
Larynx [NX]
Lens [NX]
Lip [NX]
Liver [NX]
Lung [NX]
Lymph node [NX]
Medulla [NX]
Midbrain [NX]
Motor cortex [NX]
Nasopharynx epithelium [NX]
Occipital cortex [NX]
Olfactory bulb [NX]
Olfactory epithelium [NX]
Oral mucosa [NX]
Ovary [NX]
Penis [NX]
Periaqueductal gray [NX]
Peritoneum [NX]
Pineal gland [NX]
Pituitary gland [NX]
Pleura [NX]
Pons [NX]
Prefrontal cortex [NX]
Prostate [NX]
Putamen [NX]
Rectum [NX]
Retina [NX]
Retrosplenial cortex [NX]
Salivary gland [NX]
Seminal vesicle [NX]
Septum [NX]
Skeletal muscle [NX]
Skin (back) [NX]
Skin (groin) [NX]
Smooth muscle (intestine) [NX]
Somatosensory cortex [NX]
Spleen [NX]
Stomach (lower) [NX]
Stomach (upper) [NX]
Subcutaneous adipose tissue [NX]
Subiculum [NX]
Substantia nigra [NX]
Superior colliculi [NX]
Synovial tissue [NX]
Temporal cortex [NX]
Testis [NX]
Thalamus [NX]
Thymus [NX]
Thyroid gland [NX]
Tongue [NX]
Tonsil [NX]
Trachea [NX]
Urethral gland [NX]
Urinary bladder [NX]
Vagus nerve [NX]
Ventral hippocampus [NX]
Ventral pallidum [NX]
Ventral spinal cord [NX]
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Gene
i
Gene name, if available.
Ensembl
x
Human ortholog
x
Gene description
x
RNA pig tissue group specificity
x
RNA pig tissue group distribution
x
RNA pig tissue group specific NX
x
HERC1
ENSSSCG00000004561
ENSG00000103657
HECT and RLD domain containing E3 ubiquitin protein ligase family member 1
Low tissue specificity
Detected in all
HERC2
ENSSSCG00000015853
ENSG00000128731
HECT and RLD domain containing E3 ubiquitin protein ligase 2
Low tissue specificity
Detected in all
HERC3
ENSSSCG00000009208
ENSG00000138641
HECT and RLD domain containing E3 ubiquitin protein ligase 3
Low tissue specificity
Detected in all
HERC4
ENSSSCG00000038913
ENSG00000148634
HECT and RLD domain containing E3 ubiquitin protein ligase 4
Low tissue specificity
Detected in all
HERC5
ENSSSCG00000030548
ENSG00000138646
HECT and RLD domain containing E3 ubiquitin protein ligase 5
Low tissue specificity
Detected in many
HERC6
ENSSSCG00000021712
ENSG00000138642
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
Low tissue specificity
Detected in many
HERPUD1
ENSSSCG00000040663
ENSG00000051108
Homocysteine inducible ER protein with ubiquitin like domain 1
Low tissue specificity
Detected in all
HERPUD2
ENSSSCG00000027389
ENSG00000122557
HERPUD family member 2
Low tissue specificity
Detected in all
HES1
ENSSSCG00000031356
ENSG00000114315
Transcription factor HES-1
Tissue enhanced
Detected in all
urinary bladder:
45.1
HES2
ENSSSCG00000034297
ENSG00000069812
Hes family bHLH transcription factor 2
Tissue enhanced
Detected in many
epididymis:
27.7
HES4
ENSSSCG00000035420
ENSG00000188290
Hes family bHLH transcription factor 4
Low tissue specificity
Detected in all
HES5
ENSSSCG00000037304
ENSG00000197921
Hes family bHLH transcription factor 5
Tissue enhanced
Detected in some
brain:
11.4
lens:
3.1
retina:
3.8
HES6
ENSSSCG00000016342
ENSG00000144485
Hes family bHLH transcription factor 6
Tissue enhanced
Detected in many
adipose tissue:
24.4
HES7
ENSSSCG00000017982
ENSG00000179111
Hes family bHLH transcription factor 7
Tissue enhanced
Detected in many
cartilage:
9.3
epididymis:
7.2
HESX1
ENSSSCG00000021207
ENSG00000163666
HESX homeobox 1
Low tissue specificity
Detected in all
HEXB
ENSSSCG00000014073
ENSG00000049860
Hexosaminidase subunit beta
Group enriched
Detected in many
epididymis:
222.2
male glands:
59.9
HEXIM2
ENSSSCG00000017335
ENSG00000168517
Hexamethylene bisacetamide inducible 2
Low tissue specificity
Detected in all
HEY1
ENSSSCG00000006159
ENSG00000164683
Hes related family bHLH transcription factor with YRPW motif 1
Low tissue specificity
Detected in all
HEY2
ENSSSCG00000004223
ENSG00000135547
Hairy/enhancer-of-split related with YRPW motif protein 2
Tissue enhanced
Detected in many
heart:
20.6
penis:
24.7
HEYL
ENSSSCG00000038956
ENSG00000163909
Hes related family bHLH transcription factor with YRPW motif-like
Low tissue specificity
Detected in many
HFE
ENSSSCG00000037682
ENSG00000010704
Hemochromatosis
Tissue enhanced
Detected in all
choroid plexus:
41.3
HFM1
ENSSSCG00000006912
ENSG00000162669
HFM1, ATP dependent DNA helicase homolog
Low tissue specificity
Detected in all
HGD
ENSSSCG00000021227
ENSG00000113924
Homogentisate 1,2-dioxygenase
Tissue enriched
Detected in many
liver:
91.2
HGF
ENSSSCG00000015403
ENSG00000019991
Hepatocyte growth factor
Tissue enhanced
Detected in many
liver:
19.6
HGH1
ENSSSCG00000026590
ENSG00000235173
HGH1 homolog
Low tissue specificity
Detected in all
HGS
ENSSSCG00000033082
ENSG00000185359
Hepatocyte growth factor-regulated tyrosine kinase substrate
Low tissue specificity
Detected in all
HHAT
ENSSSCG00000015607
ENSG00000054392
Hedgehog acyltransferase
Tissue enhanced
Detected in all
testis:
31.8
HHIP
ENSSSCG00000009045
ENSG00000164161
Hedgehog interacting protein
Tissue enhanced
Detected in many
cartilage:
79.0
lymphoid tissue:
59.2
HHIPL2
ENSSSCG00000010832
ENSG00000143512
HHIP like 2
Group enriched
Detected in many
cartilage:
71.0
synovial tissue:
27.8
HHLA2
ENSSSCG00000027275
ENSG00000114455
HERV-H LTR-associating 2
Group enriched
Detected in all
kidney:
61.9
large intestine:
31.9
liver:
58.9
small intestine:
46.3
HIBADH
ENSSSCG00000016695
ENSG00000106049
3-hydroxyisobutyrate dehydrogenase
Low tissue specificity
Detected in all
HIBCH
ENSSSCG00000016049
ENSG00000198130
3-hydroxyisobutyryl-CoA hydrolase
Low tissue specificity
Detected in all
HIC1
ENSSSCG00000025717
ENSG00000177374
HIC ZBTB transcriptional repressor 1
Low tissue specificity
Detected in many
HIC2
ENSSSCG00000036472
ENSG00000169635
HIC ZBTB transcriptional repressor 2
Low tissue specificity
Detected in all
HID1
ENSSSCG00000017219
ENSG00000167861
HID1 domain containing
Tissue enhanced
Detected in many
male glands:
54.1
stomach:
43.9
HIF1A
ENSSSCG00000005096
ENSG00000100644
Hypoxia-inducible factor 1-alpha
Tissue enhanced
Detected in all
cartilage:
106.3
HIF1AN
ENSSSCG00000010555
ENSG00000166135
Hypoxia inducible factor 1 alpha subunit inhibitor
Low tissue specificity
Detected in all
HIF3A
ENSSSCG00000003101
ENSG00000124440
Hypoxia inducible factor 3 alpha subunit
Tissue enhanced
Detected in many
breast:
38.6
heart:
44.0
HIGD1B
ENSSSCG00000017347
ENSG00000131097
HIG1 hypoxia inducible domain family member 1B
Low tissue specificity
Detected in many
HIGD1C
ENSSSCG00000035326
ENSG00000214511
HIG1 hypoxia inducible domain family member 1C
Low tissue specificity
Detected in many
HIGD2A
ENSSSCG00000029179
ENSG00000146066,ENSG00000175202
HIG1 domain family member 2A, mitochondrial
Low tissue specificity
Detected in all
HIKESHI
ENSSSCG00000021210
ENSG00000149196
Hikeshi, heat shock protein nuclear import factor
Tissue enhanced
Detected in all
lens:
60.3
HILPDA
ENSSSCG00000031109
ENSG00000135245
Hypoxia-inducible lipid droplet-associated protein
Low tissue specificity
Detected in all
HINFP
ENSSSCG00000015112
ENSG00000172273
Histone H4 transcription factor
Low tissue specificity
Detected in all
HIP1
ENSSSCG00000007700
ENSG00000127946
Huntingtin interacting protein 1
Low tissue specificity
Detected in all
HIP1R
ENSSSCG00000009786
ENSG00000130787
Huntingtin interacting protein 1 related
Low tissue specificity
Detected in many
HIPK1
ENSSSCG00000006760
ENSG00000163349
Homeodomain interacting protein kinase 1
Low tissue specificity
Detected in all
HIPK2
ENSSSCG00000026733
ENSG00000064393
Homeodomain interacting protein kinase 2
Low tissue specificity
Detected in all
HIPK3
ENSSSCG00000013312
ENSG00000110422
Homeodomain interacting protein kinase 3
Tissue enhanced
Detected in all
lens:
111.4
HIPK4
ENSSSCG00000021917
ENSG00000160396
Homeodomain interacting protein kinase 4
Tissue enriched
Detected in many
testis:
55.0
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