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Human disease related genes
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UMAP gene cluster
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Keyword
Chromosome
1
2
3
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5
6
7
8
9
10
11
12
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14
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MT
Unmapped
X
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External id
Variability
Variable
Not variable
Tissue
Any
Adipose tissue
Brain
Cartilage
Heart
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Large intestine
Lymphoid tissue
Male glands
Mesothelial tissue
Mouth
Skin
Small intestine
Stomach 1
Upper respiratory system
Cluster
1 - Brain neurotransmission
2 - Brain neurotransmission
3 - Brain cellular structure
4 - Brain development
5 - Intracellular signalling
6 - Brain uncharacterized
7 - Retinal
8 - Neurohormonal
9 - Testis spermatogenesis
10 - Housekeeping transcription
11 - Testis uncharacterized
12 - Metabolic
13 - Testis sperm
14 - Low abundant uncharacterized
15 - Testis uncharacterized
16 - Aorta uncharacterized
17 - Cilium structure
18 - Low abundant uncharacterized
19 - Housekeeping mitochondrial
20 - Hormonal
21 - Low abundant uncharacterized
22 - Housekeeping transcription
23 - Cilium structure
24 - Low abundant uncharacterized
25 - Low abundant uncharacterized
26 - Low abundant uncharacterized
27 - Low abundant uncharacterized
28 - Housekeeping mitochondrial translation
29 - Male tissue bacterial defense
30 - Housekeeping structural
31 - Housekeeping uncharacterized
32 - Transport
33 - Lens
34 - Prostate uncharacterized
35 - Low abundant uncharacterized
36 - Receptors uncharacterized
37 - Olfactory bulb
38 - Lung and thyroid development
39 - Kidney transport
40 - Testis
41 - Low abundant uncharacterized
42 - Low abundant uncharacterized
43 - Breast uncharacterized
44 - Housekeeping
45 - Thymus uncharacterized
46 - Skeletal muscle contraction
47 - Spleen uncharacterized
48 - Low abundant uncharacterized
49 - Heart contraction
50 - Muscle contraction
51 - Liver and kidney
52 - Housekeeping
53 - Housekeeping mitochondrial
54 - Interferons
55 - Low abundant uncharacterized
56 - Low abundant uncharacterized
57 - Skin
58 - Immune cells
59 - Squamous epithelium
60 - Not detected
61 - Enzymes and secretion
62 - Squamous epithelium
63 - Small intestine
64 - Gastrointestinal
65 - Epithelium
66 - Housekeeping mRNA
67 - Gastrointestinal
68 - Housekeeping protein processing
69 - Housekeeping
70 - Housekeeping
71 - Housekeeping regulation
72 - Digestive and respiratory defense
73 - Housekeeping cell cycle
74 - Extracellular matrix
75 - Housekeeping
76 - Housekeeping regulation
77 - Housekeeping defense
78 - Lymphoid T cells
79 - Lymphoid myeloid
80 - Heart uncharacterized
81 - Vasculature and connective tissue
82 - Lymphoid B cell
83 - Not detected
84 - Epithelium transcription regulation
Tissue group
Any
Adipose tissue
Adrenal gland
Aorta
Bone marrow
Brain
Breast
Cartilage
Cervix
Choroid plexus
Cornea
Ductus deferens
Dura mater
Endometrium
Epididymis
Esophagus
Fallopian tube
Gallbladder
Heart
Kidney
Large intestine
Lens
Liver
Lung
Lymphoid tissue
Male glands
Mesothelial tissue
Mouth
Ovary
Penis
Pineal gland
Pituitary gland
Retina
Salivary gland
Skeletal muscle
Skin
Small intestine
Smooth muscle
Stomach
Synovial tissue
Testis
Thyroid gland
Upper respiratory system
Urinary bladder
Vagus nerve
Category
Tissue enriched
Group enriched
Tissue enhanced
Low tissue specificity
Not detected
Detected in all
Detected in many
Detected in some
Detected in single
Is highest expressed
Brain region
Any
Amygdala
Basal ganglia
Cerebellum
Cerebral cortex
Corpus callosum
Hippocampal formation
Hypothalamus
Midbrain
Olfactory region
Pituitary gland
Pons and medulla
Retina
Spinal cord
Thalamus
Category
Region enriched
Group enriched
Region enhanced
Low region specificity
Not detected
Detected in all
Detected in many
Detected in some
Detected in single
Is highest expressed
Column
Gene
Position
Tissue specific score
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THE PIG PROTEOME
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TISSUE SPECIFIC PROTEOME
UMAP GENE CLUSTERING
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16894 GENES FOUND
Gene
Gene
i
Gene name, if available.
Gene synonym (Human ortholog)
Ensembl gene id
Ensembl gene id (Proteincoding human ortholog)
Gene description
Uniprot accession (Human ortholog)
Chromosome
Chromosome position
Related human disease
RNA category pig
RNA pig tissue group specificity
RNA pig tissue group distribution
RNA pig tissue group specificity score
RNA pig tissue group specific NX
RNA pig brain regional specificity
RNA pig brain regional distribution
RNA pig brain regional specificity score
RNA pig brain regional specific pTPM
Annotation
UMAP cluster
Within tissue variation
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Select data columns:
Gene
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Gene
i
Gene name, if available.
Gene synonym (Human ortholog)
Ensembl gene id
Ensembl gene id (Proteincoding human ortholog)
Gene description
Uniprot accession (Human ortholog)
Chromosome
Chromosome position
Related human disease
RNA category pig
Expand
RNA pig tissue group specificity
RNA pig tissue group distribution
RNA pig tissue group specificity score
RNA pig tissue group specific NX
RNA pig brain regional specificity
RNA pig brain regional distribution
RNA pig brain regional specificity score
RNA pig brain regional specific pTPM
Annotation
Expand
UMAP cluster
Within tissue variation
Pig Tissue RNA
Expand
Abdominal adipose tissue [NX]
Adrenal gland [NX]
Amygdala [NX]
Aorta [NX]
Bone marrow [NX]
Breast [NX]
Bronchus [NX]
Bulbourethral gland [NX]
Caudate [NX]
Cecum [NX]
Cerebellum [NX]
Cervix [NX]
Choroid plexus [NX]
Cingulate cortex [NX]
Colon [NX]
Cornea [NX]
Corpus callosum [NX]
Dorsal hippocampus [NX]
Dorsal spinal cord [NX]
Ductus deferens [NX]
Duodenum [NX]
Dura mater [NX]
Ear cartilage [NX]
Endometrium 1 [NX]
Entorhinal cortex [NX]
Epididymis [NX]
Esophagus [NX]
Facial adipose tissue [NX]
Fallopian tube [NX]
Gallbladder [NX]
Heart atrium [NX]
Heart valve [NX]
Heart wall [NX]
Hypothalamus [NX]
Ileum [NX]
Insular cortex [NX]
Jejunum [NX]
Joint cartilage [NX]
Kidney (cortex) [NX]
Kidney (medulla) [NX]
Larynx [NX]
Lens [NX]
Lip [NX]
Liver [NX]
Lung [NX]
Lymph node [NX]
Medulla [NX]
Midbrain [NX]
Motor cortex [NX]
Nasopharynx epithelium [NX]
Occipital cortex [NX]
Olfactory bulb [NX]
Olfactory epithelium [NX]
Oral mucosa [NX]
Ovary [NX]
Penis [NX]
Periaqueductal gray [NX]
Peritoneum [NX]
Pineal gland [NX]
Pituitary gland [NX]
Pleura [NX]
Pons [NX]
Prefrontal cortex [NX]
Prostate [NX]
Putamen [NX]
Rectum [NX]
Retina [NX]
Retrosplenial cortex [NX]
Salivary gland [NX]
Seminal vesicle [NX]
Septum [NX]
Skeletal muscle [NX]
Skin (back) [NX]
Skin (groin) [NX]
Smooth muscle (intestine) [NX]
Somatosensory cortex [NX]
Spleen [NX]
Stomach (lower) [NX]
Stomach (upper) [NX]
Subcutaneous adipose tissue [NX]
Subiculum [NX]
Substantia nigra [NX]
Superior colliculi [NX]
Synovial tissue [NX]
Temporal cortex [NX]
Testis [NX]
Thalamus [NX]
Thymus [NX]
Thyroid gland [NX]
Tongue [NX]
Tonsil [NX]
Trachea [NX]
Urethral gland [NX]
Urinary bladder [NX]
Vagus nerve [NX]
Ventral hippocampus [NX]
Ventral pallidum [NX]
Ventral spinal cord [NX]
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Gene
i
Gene name, if available.
Ensembl
x
Human ortholog
x
Gene description
x
RNA pig tissue group specificity
x
RNA pig tissue group distribution
x
RNA pig tissue group specific NX
x
HMGCLL1
ENSSSCG00000001479
ENSG00000146151
3-hydroxymethyl-3-methylglutaryl-CoA lyase like 1
Tissue enhanced
Detected in many
brain:
20.2
HMGCR
ENSSSCG00000014080
ENSG00000113161
3-hydroxy-3-methylglutaryl-coenzyme A reductase
Tissue enhanced
Detected in all
ovary:
72.7
HMGCS1
ENSSSCG00000016872
ENSG00000112972
Hydroxymethylglutaryl-CoA synthase, cytoplasmic
Tissue enhanced
Detected in all
brain:
90.9
ovary:
47.5
HMGCS2
ENSSSCG00000036808
ENSG00000134240
Hydroxymethylglutaryl-CoA synthase, mitochondrial
Tissue enriched
Detected in all
large intestine:
116.1
HMGN2
ENSSSCG00000003555
Non-histone chromosomal protein HMG-17
Low tissue specificity
Detected in all
HMGN3
ENSSSCG00000004470
ENSG00000118418
High mobility group nucleosome-binding domain-containing protein 3
Low tissue specificity
Detected in all
HMGN4
ENSSSCG00000020696
ENSG00000182952
High mobility group nucleosomal binding domain 4
Low tissue specificity
Detected in all
HMGN5
ENSSSCG00000032946
ENSG00000198157
High mobility group nucleosome binding domain 5
Tissue enhanced
Detected in all
lymphoid tissue:
21.5
HMGXB3
ENSSSCG00000014440
ENSG00000113716
HMG-box containing 3
Low tissue specificity
Detected in all
HMGXB4
ENSSSCG00000025780
ENSG00000100281
HMG-box containing 4
Low tissue specificity
Detected in all
HMMR
ENSSSCG00000017022
ENSG00000072571
Hyaluronan mediated motility receptor
Low tissue specificity
Detected in all
HMOX1
ENSSSCG00000039745
ENSG00000100292
Heme oxygenase 1
Tissue enriched
Detected in many
lymphoid tissue:
118.9
HMOX2
ENSSSCG00000007942
ENSG00000103415
Heme oxygenase 2
Low tissue specificity
Detected in all
HNF1B
ENSSSCG00000022417
ENSG00000275410
Hepatocyte nuclear factor 1-beta
Tissue enhanced
Detected in many
gallbladder:
24.5
kidney:
75.6
HNF4G
ENSSSCG00000034242
ENSG00000164749
Hepatocyte nuclear factor 4 gamma
Group enriched
Detected in some
large intestine:
44.1
small intestine:
52.4
HNMT
ENSSSCG00000035195
ENSG00000150540
Histamine N-methyltransferase
Low tissue specificity
Detected in all
HNRNPA2B1
ENSSSCG00000036350
ENSG00000122566
Heterogeneous nuclear ribonucleoprotein A2/B1
Low tissue specificity
Detected in all
HNRNPD
ENSSSCG00000009249
ENSG00000138668
Heterogeneous nuclear ribonucleoprotein D
Low tissue specificity
Detected in all
HNRNPDL
ENSSSCG00000037245
ENSG00000152795
Heterogeneous nuclear ribonucleoprotein D like
Low tissue specificity
Detected in all
HNRNPF
ENSSSCG00000010203
ENSG00000169813
Heterogeneous nuclear ribonucleoprotein F
Low tissue specificity
Detected in all
HNRNPH1
ENSSSCG00000014022
ENSG00000169045
Heterogeneous nuclear ribonucleoprotein H1
Low tissue specificity
Detected in all
HNRNPH2
ENSSSCG00000033161
ENSG00000126945
Heterogeneous nuclear ribonucleoprotein H2
Low tissue specificity
Detected in all
HNRNPH3
ENSSSCG00000010238
ENSG00000096746
Heterogeneous nuclear ribonucleoprotein H3
Low tissue specificity
Detected in all
HNRNPLL
ENSSSCG00000020878
ENSG00000143889
Heterogeneous nuclear ribonucleoprotein L like
Low tissue specificity
Detected in all
HNRNPM
ENSSSCG00000013602
ENSG00000099783
Heterogeneous nuclear ribonucleoprotein M
Low tissue specificity
Detected in all
HNRNPR
ENSSSCG00000023761
ENSG00000125944
Heterogeneous nuclear ribonucleoprotein R
Low tissue specificity
Detected in all
HNRNPU
ENSSSCG00000010877
ENSG00000153187
Heterogeneous nuclear ribonucleoprotein U
Low tissue specificity
Detected in all
HNRNPUL1
ENSSSCG00000030049
ENSG00000105323
Heterogeneous nuclear ribonucleoprotein U like 1
Low tissue specificity
Detected in all
HOGA1
ENSSSCG00000010523
ENSG00000241935
4-hydroxy-2-oxoglutarate aldolase, mitochondrial
Group enriched
Detected in many
kidney:
67.9
liver:
30.6
HOMER1
ENSSSCG00000014113
ENSG00000152413
Homer protein homolog 1
Tissue enhanced
Detected in many
brain:
51.9
skeletal muscle:
39.4
HOMER2
ENSSSCG00000001804
ENSG00000103942
Homer scaffolding protein 2
Tissue enhanced
Detected in many
salivary gland:
47.6
HOMER3
ENSSSCG00000013919
ENSG00000051128
Homer scaffolding protein 3
Tissue enhanced
Detected in many
cornea:
25.4
skeletal muscle:
30.3
HOMEZ
ENSSSCG00000028190
ENSG00000215271
Homeobox and leucine zipper encoding
Tissue enhanced
Detected in all
testis:
53.1
HOOK1
ENSSSCG00000003826
ENSG00000134709
Hook microtubule tethering protein 1
Tissue enhanced
Detected in many
pineal gland:
51.2
salivary gland:
64.1
testis:
39.8
HOOK2
ENSSSCG00000013734
ENSG00000095066
Hook microtubule tethering protein 2
Low tissue specificity
Detected in many
HOXA1
ENSSSCG00000016707
ENSG00000105991
Homeobox A1
Tissue enhanced
Detected in many
upper respiratory system:
18.7
HOXA2
ENSSSCG00000016706
ENSG00000105996
Homeobox A2
Tissue enhanced
Detected in many
male glands:
21.9
HOXA3
ENSSSCG00000016705
ENSG00000105997
Homeobox A3
Low tissue specificity
Detected in many
HOXA4
ENSSSCG00000016704
ENSG00000197576
Homeobox A4
Tissue enhanced
Detected in many
male glands:
28.6
HOXA5
ENSSSCG00000016703
ENSG00000106004
Homeobox protein Hox-A5
Tissue enhanced
Detected in many
epididymis:
34.4
male glands:
42.7
HOXB2
ENSSSCG00000017533
ENSG00000173917
Homeobox B2
Tissue enhanced
Detected in many
male glands:
48.0
HOXB3
ENSSSCG00000017534
ENSG00000120093
Homeobox B3
Tissue enhanced
Detected in many
male glands:
64.2
HOXB4
ENSSSCG00000017535
ENSG00000182742
Homeobox B4
Tissue enhanced
Detected in many
epididymis:
47.8
male glands:
83.5
HOXB5
ENSSSCG00000017540
ENSG00000120075
Homeobox B5
Tissue enhanced
Detected in many
epididymis:
17.9
male glands:
17.7
HOXB6
ENSSSCG00000017539
ENSG00000108511
Homeobox B6
Group enriched
Detected in many
epididymis:
55.3
male glands:
186.0
HOXB7
ENSSSCG00000017538
ENSG00000260027
Homeobox B7
Tissue enhanced
Detected in many
epididymis:
21.7
male glands:
15.6
HOXB8
ENSSSCG00000017537
ENSG00000120068
Homeobox B8
Tissue enhanced
Detected in many
epididymis:
62.0
male glands:
53.0
HOXD3
ENSSSCG00000015985
ENSG00000128652
Homeobox D3
Tissue enhanced
Detected in many
epididymis:
21.2
kidney:
23.0
male glands:
57.4
HOXD4
ENSSSCG00000015984
ENSG00000170166
Homeobox D4
Tissue enhanced
Detected in many
epididymis:
59.9
kidney:
38.0
male glands:
48.8
HOXD9
ENSSSCG00000015982
ENSG00000128709
Homeobox D9
Tissue enhanced
Detected in many
cartilage:
40.7
epididymis:
30.9
kidney:
34.1
male glands:
31.3
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