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Human disease related genes
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UMAP gene cluster
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Subclass
Class
Biological process
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Disease
Keyword
Chromosome
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
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18
MT
Unmapped
X
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External id
Variability
Variable
Not variable
Tissue
Any
Adipose tissue
Brain
Cartilage
Heart
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Large intestine
Lymphoid tissue
Male glands
Mesothelial tissue
Mouth
Skin
Small intestine
Stomach 1
Upper respiratory system
Cluster
1 - Brain neurotransmission
2 - Brain neurotransmission
3 - Brain cellular structure
4 - Brain development
5 - Intracellular signalling
6 - Brain uncharacterized
7 - Retinal
8 - Neurohormonal
9 - Testis spermatogenesis
10 - Housekeeping transcription
11 - Testis uncharacterized
12 - Metabolic
13 - Testis sperm
14 - Low abundant uncharacterized
15 - Testis uncharacterized
16 - Aorta uncharacterized
17 - Cilium structure
18 - Low abundant uncharacterized
19 - Housekeeping mitochondrial
20 - Hormonal
21 - Low abundant uncharacterized
22 - Housekeeping transcription
23 - Cilium structure
24 - Low abundant uncharacterized
25 - Low abundant uncharacterized
26 - Low abundant uncharacterized
27 - Low abundant uncharacterized
28 - Housekeeping mitochondrial translation
29 - Male tissue bacterial defense
30 - Housekeeping structural
31 - Housekeeping uncharacterized
32 - Transport
33 - Lens
34 - Prostate uncharacterized
35 - Low abundant uncharacterized
36 - Receptors uncharacterized
37 - Olfactory bulb
38 - Lung and thyroid development
39 - Kidney transport
40 - Testis
41 - Low abundant uncharacterized
42 - Low abundant uncharacterized
43 - Breast uncharacterized
44 - Housekeeping
45 - Thymus uncharacterized
46 - Skeletal muscle contraction
47 - Spleen uncharacterized
48 - Low abundant uncharacterized
49 - Heart contraction
50 - Muscle contraction
51 - Liver and kidney
52 - Housekeeping
53 - Housekeeping mitochondrial
54 - Interferons
55 - Low abundant uncharacterized
56 - Low abundant uncharacterized
57 - Skin
58 - Immune cells
59 - Squamous epithelium
60 - Not detected
61 - Enzymes and secretion
62 - Squamous epithelium
63 - Small intestine
64 - Gastrointestinal
65 - Epithelium
66 - Housekeeping mRNA
67 - Gastrointestinal
68 - Housekeeping protein processing
69 - Housekeeping
70 - Housekeeping
71 - Housekeeping regulation
72 - Digestive and respiratory defense
73 - Housekeeping cell cycle
74 - Extracellular matrix
75 - Housekeeping
76 - Housekeeping regulation
77 - Housekeeping defense
78 - Lymphoid T cells
79 - Lymphoid myeloid
80 - Heart uncharacterized
81 - Vasculature and connective tissue
82 - Lymphoid B cell
83 - Not detected
84 - Epithelium transcription regulation
Tissue group
Any
Adipose tissue
Adrenal gland
Aorta
Bone marrow
Brain
Breast
Cartilage
Cervix
Choroid plexus
Cornea
Ductus deferens
Dura mater
Endometrium
Epididymis
Esophagus
Fallopian tube
Gallbladder
Heart
Kidney
Large intestine
Lens
Liver
Lung
Lymphoid tissue
Male glands
Mesothelial tissue
Mouth
Ovary
Penis
Pineal gland
Pituitary gland
Retina
Salivary gland
Skeletal muscle
Skin
Small intestine
Smooth muscle
Stomach
Synovial tissue
Testis
Thyroid gland
Upper respiratory system
Urinary bladder
Vagus nerve
Category
Tissue enriched
Group enriched
Tissue enhanced
Low tissue specificity
Not detected
Detected in all
Detected in many
Detected in some
Detected in single
Is highest expressed
Brain region
Any
Amygdala
Basal ganglia
Cerebellum
Cerebral cortex
Corpus callosum
Hippocampal formation
Hypothalamus
Midbrain
Olfactory region
Pituitary gland
Pons and medulla
Retina
Spinal cord
Thalamus
Category
Region enriched
Group enriched
Region enhanced
Low region specificity
Not detected
Detected in all
Detected in many
Detected in some
Detected in single
Is highest expressed
Column
Gene
Position
Tissue specific score
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THE PIG PROTEOME
THE PIG ATLAS
TISSUE SPECIFIC PROTEOME
UMAP GENE CLUSTERING
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16894 GENES FOUND
Gene
Gene
i
Gene name, if available.
Gene synonym (Human ortholog)
Ensembl gene id
Ensembl gene id (Proteincoding human ortholog)
Gene description
Uniprot accession (Human ortholog)
Chromosome
Chromosome position
Related human disease
RNA category pig
RNA pig tissue group specificity
RNA pig tissue group distribution
RNA pig tissue group specificity score
RNA pig tissue group specific NX
RNA pig brain regional specificity
RNA pig brain regional distribution
RNA pig brain regional specificity score
RNA pig brain regional specific pTPM
Annotation
UMAP cluster
Within tissue variation
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Select data columns:
Gene
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Gene
i
Gene name, if available.
Gene synonym (Human ortholog)
Ensembl gene id
Ensembl gene id (Proteincoding human ortholog)
Gene description
Uniprot accession (Human ortholog)
Chromosome
Chromosome position
Related human disease
RNA category pig
Expand
RNA pig tissue group specificity
RNA pig tissue group distribution
RNA pig tissue group specificity score
RNA pig tissue group specific NX
RNA pig brain regional specificity
RNA pig brain regional distribution
RNA pig brain regional specificity score
RNA pig brain regional specific pTPM
Annotation
Expand
UMAP cluster
Within tissue variation
Pig Tissue RNA
Expand
Abdominal adipose tissue [NX]
Adrenal gland [NX]
Amygdala [NX]
Aorta [NX]
Bone marrow [NX]
Breast [NX]
Bronchus [NX]
Bulbourethral gland [NX]
Caudate [NX]
Cecum [NX]
Cerebellum [NX]
Cervix [NX]
Choroid plexus [NX]
Cingulate cortex [NX]
Colon [NX]
Cornea [NX]
Corpus callosum [NX]
Dorsal hippocampus [NX]
Dorsal spinal cord [NX]
Ductus deferens [NX]
Duodenum [NX]
Dura mater [NX]
Ear cartilage [NX]
Endometrium 1 [NX]
Entorhinal cortex [NX]
Epididymis [NX]
Esophagus [NX]
Facial adipose tissue [NX]
Fallopian tube [NX]
Gallbladder [NX]
Heart atrium [NX]
Heart valve [NX]
Heart wall [NX]
Hypothalamus [NX]
Ileum [NX]
Insular cortex [NX]
Jejunum [NX]
Joint cartilage [NX]
Kidney (cortex) [NX]
Kidney (medulla) [NX]
Larynx [NX]
Lens [NX]
Lip [NX]
Liver [NX]
Lung [NX]
Lymph node [NX]
Medulla [NX]
Midbrain [NX]
Motor cortex [NX]
Nasopharynx epithelium [NX]
Occipital cortex [NX]
Olfactory bulb [NX]
Olfactory epithelium [NX]
Oral mucosa [NX]
Ovary [NX]
Penis [NX]
Periaqueductal gray [NX]
Peritoneum [NX]
Pineal gland [NX]
Pituitary gland [NX]
Pleura [NX]
Pons [NX]
Prefrontal cortex [NX]
Prostate [NX]
Putamen [NX]
Rectum [NX]
Retina [NX]
Retrosplenial cortex [NX]
Salivary gland [NX]
Seminal vesicle [NX]
Septum [NX]
Skeletal muscle [NX]
Skin (back) [NX]
Skin (groin) [NX]
Smooth muscle (intestine) [NX]
Somatosensory cortex [NX]
Spleen [NX]
Stomach (lower) [NX]
Stomach (upper) [NX]
Subcutaneous adipose tissue [NX]
Subiculum [NX]
Substantia nigra [NX]
Superior colliculi [NX]
Synovial tissue [NX]
Temporal cortex [NX]
Testis [NX]
Thalamus [NX]
Thymus [NX]
Thyroid gland [NX]
Tongue [NX]
Tonsil [NX]
Trachea [NX]
Urethral gland [NX]
Urinary bladder [NX]
Vagus nerve [NX]
Ventral hippocampus [NX]
Ventral pallidum [NX]
Ventral spinal cord [NX]
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Gene
i
Gene name, if available.
Ensembl
x
Human ortholog
x
Gene description
x
RNA pig tissue group specificity
x
RNA pig tissue group distribution
x
RNA pig tissue group specific NX
x
LRAT
ENSSSCG00000008995
ENSG00000121207
Lecithin retinol acyltransferase
Low tissue specificity
Detected in all
LRBA
ENSSSCG00000009021
ENSG00000198589
LPS responsive beige-like anchor protein
Tissue enhanced
Detected in all
fallopian tube:
98.5
LRCH1
ENSSSCG00000009408
ENSG00000136141
Leucine rich repeats and calponin homology domain containing 1
Low tissue specificity
Detected in all
LRCH2
ENSSSCG00000012595
ENSG00000130224
Leucine rich repeats and calponin homology domain containing 2
Low tissue specificity
Detected in many
LRCH3
ENSSSCG00000011854
ENSG00000186001
Leucine rich repeats and calponin homology domain containing 3
Low tissue specificity
Detected in all
LRCH4
ENSSSCG00000007667
ENSG00000077454
Leucine rich repeats and calponin homology domain containing 4
Tissue enhanced
Detected in all
lymphoid tissue:
78.2
LRFN1
ENSSSCG00000032407
ENSG00000128011
Leucine rich repeat and fibronectin type III domain containing 1
Tissue enhanced
Detected in many
brain:
15.7
LRFN2
ENSSSCG00000001597
ENSG00000156564
Leucine rich repeat and fibronectin type III domain containing 2
Tissue enhanced
Detected in many
brain:
11.4
retina:
20.9
LRFN3
ENSSSCG00000002927
ENSG00000126243
Leucine rich repeat and fibronectin type III domain containing 3
Tissue enhanced
Detected in many
brain:
16.3
LRFN4
ENSSSCG00000039360
ENSG00000173621
Leucine rich repeat and fibronectin type III domain containing 4
Tissue enhanced
Detected in many
adipose tissue:
35.7
LRFN5
ENSSSCG00000004990
ENSG00000165379
Leucine rich repeat and fibronectin type III domain containing 5
Tissue enhanced
Detected in many
brain:
16.9
cervix:
11.5
LRG1
ENSSSCG00000013514
ENSG00000171236
Leucine rich alpha-2-glycoprotein 1
Tissue enriched
Detected in many
liver:
64.1
LRGUK
ENSSSCG00000016542
ENSG00000155530
Leucine rich repeats and guanylate kinase domain containing
Tissue enhanced
Detected in many
brain:
16.3
fallopian tube:
35.2
upper respiratory system:
19.4
LRIF1
ENSSSCG00000006799
ENSG00000121931
Ligand dependent nuclear receptor interacting factor 1
Group enriched
Detected in all
lens:
36.7
retina:
17.1
testis:
43.6
LRIG1
ENSSSCG00000011499
ENSG00000144749
Leucine rich repeats and immunoglobulin like domains 1
Tissue enhanced
Detected in all
male glands:
68.7
LRIG2
ENSSSCG00000034581
ENSG00000198799
Leucine rich repeats and immunoglobulin like domains 2
Low tissue specificity
Detected in all
LRIG3
ENSSSCG00000000455
ENSG00000139263
Leucine rich repeats and immunoglobulin like domains 3
Low tissue specificity
Detected in many
LRIT1
ENSSSCG00000034402
ENSG00000148602
Leucine rich repeat, Ig-like and transmembrane domains 1
Tissue enriched
Detected in all
retina:
50.8
LRIT3
ENSSSCG00000009135
ENSG00000183423
Leucine rich repeat, Ig-like and transmembrane domains 3
Tissue enriched
Detected in many
retina:
49.8
LRMDA
ENSSSCG00000034308
ENSG00000148655
Leucine rich melanocyte differentiation associated
Low tissue specificity
Detected in many
LRMP
ENSSSCG00000000563
ENSG00000118308
Lymphoid restricted membrane protein
Tissue enhanced
Detected in many
lymphoid tissue:
77.5
upper respiratory system:
34.9
LRP1
ENSSSCG00000000423
ENSG00000123384
LDL receptor related protein 1
Tissue enhanced
Detected in all
cartilage:
102.7
LRP10
ENSSSCG00000034465
ENSG00000197324
Low-density lipoprotein receptor-related protein 10 precursor
Low tissue specificity
Detected in all
LRP11
ENSSSCG00000004101
ENSG00000120256
LDL receptor related protein 11
Tissue enhanced
Detected in all
pineal gland:
61.1
LRP12
ENSSSCG00000006039
ENSG00000147650
Low-density lipoprotein receptor-related protein 12 precursor
Low tissue specificity
Detected in all
LRP2BP
ENSSSCG00000015792
ENSG00000109771
LRP2-binding protein
Low tissue specificity
Detected in all
LRP3
ENSSSCG00000002863
ENSG00000130881
LDL receptor related protein 3
Low tissue specificity
Detected in all
LRP4
ENSSSCG00000013248
ENSG00000134569
LDL receptor related protein 4
Tissue enhanced
Detected in many
skin:
40.7
small intestine:
32.8
LRP5
ENSSSCG00000012885
ENSG00000162337
LDL receptor related protein 5
Low tissue specificity
Detected in all
LRP6
ENSSSCG00000000625
ENSG00000070018
LDL receptor related protein 6
Low tissue specificity
Detected in all
LRP8
ENSSSCG00000003848
ENSG00000157193
Low-density lipoprotein receptor-related protein 8 precursor
Tissue enhanced
Detected in many
brain:
30.5
ovary:
21.9
LRPAP1
ENSSSCG00000008701
ENSG00000163956
Alpha-2-macroglobulin receptor-associated protein precursor
Low tissue specificity
Detected in all
LRPPRC
ENSSSCG00000008452
ENSG00000138095
Leucine rich pentatricopeptide repeat containing
Low tissue specificity
Detected in all
LRR1
ENSSSCG00000005004
ENSG00000165501
Leucine rich repeat protein 1
Low tissue specificity
Detected in all
LRRC1
ENSSSCG00000001486
ENSG00000137269
Leucine rich repeat containing 1
Low tissue specificity
Detected in many
LRRC10B
ENSSSCG00000013088
ENSG00000204950
Leucine rich repeat containing 10B
Tissue enhanced
Detected in many
brain:
23.1
fallopian tube:
32.9
upper respiratory system:
32.2
LRRC14
ENSSSCG00000030451
ENSG00000160959
Leucine rich repeat containing 14
Low tissue specificity
Detected in all
LRRC14B
ENSSSCG00000033375
ENSG00000185028
Leucine rich repeat containing 14B
Low tissue specificity
Detected in all
LRRC15
ENSSSCG00000026868
ENSG00000172061
Leucine rich repeat containing 15
Tissue enhanced
Detected in some
adrenal gland:
54.8
dura mater:
10.9
skin:
27.9
LRRC17
ENSSSCG00000036452
ENSG00000128606
Leucine rich repeat containing 17
Tissue enhanced
Detected in many
heart:
29.1
male glands:
28.8
synovial tissue:
26.6
LRRC18
ENSSSCG00000010384
ENSG00000165383
Leucine rich repeat containing 18
Tissue enhanced
Detected in some
choroid plexus:
19.8
testis:
86.6
upper respiratory system:
24.4
LRRC19
ENSSSCG00000005125
ENSG00000184434
Leucine rich repeat containing 19
Tissue enhanced
Detected in all
large intestine:
21.4
LRRC2
ENSSSCG00000026945
ENSG00000163827
Leucine-rich repeat-containing protein 2
Group enriched
Detected in many
heart:
70.2
skeletal muscle:
50.1
LRRC20
ENSSSCG00000010267
ENSG00000172731
Leucine rich repeat containing 20
Tissue enhanced
Detected in all
skeletal muscle:
38.2
LRRC23
ENSSSCG00000000679
ENSG00000010626
Leucine rich repeat containing 23
Tissue enhanced
Detected in many
fallopian tube:
24.2
lung:
15.1
testis:
26.6
upper respiratory system:
24.0
LRRC24
ENSSSCG00000005896
ENSG00000254402
Leucine rich repeat containing 24
Low tissue specificity
Detected in all
LRRC25
ENSSSCG00000036963
ENSG00000175489
Leucine rich repeat containing 25
Low tissue specificity
Detected in all
LRRC26
ENSSSCG00000032509
ENSG00000184709
Leucine rich repeat containing 26
Tissue enriched
Detected in many
male glands:
160.2
LRRC28
ENSSSCG00000004814
ENSG00000168904
Leucine rich repeat containing 28
Low tissue specificity
Detected in all
LRRC3
ENSSSCG00000027975
ENSG00000160233
Leucine rich repeat containing 3
Tissue enhanced
Detected in many
liver:
47.7
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