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Human disease related genes
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UMAP gene cluster
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Subclass
Class
Biological process
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Disease
Keyword
Chromosome
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
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18
MT
Unmapped
X
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External id
Variability
Variable
Not variable
Tissue
Any
Adipose tissue
Brain
Cartilage
Heart
Kidney
Large intestine
Lymphoid tissue
Male glands
Mesothelial tissue
Mouth
Skin
Small intestine
Stomach 1
Upper respiratory system
Cluster
1 - Brain neurotransmission
2 - Brain neurotransmission
3 - Brain cellular structure
4 - Brain development
5 - Intracellular signalling
6 - Brain uncharacterized
7 - Retinal
8 - Neurohormonal
9 - Testis spermatogenesis
10 - Housekeeping transcription
11 - Testis uncharacterized
12 - Metabolic
13 - Testis sperm
14 - Low abundant uncharacterized
15 - Testis uncharacterized
16 - Aorta uncharacterized
17 - Cilium structure
18 - Low abundant uncharacterized
19 - Housekeeping mitochondrial
20 - Hormonal
21 - Low abundant uncharacterized
22 - Housekeeping transcription
23 - Cilium structure
24 - Low abundant uncharacterized
25 - Low abundant uncharacterized
26 - Low abundant uncharacterized
27 - Low abundant uncharacterized
28 - Housekeeping mitochondrial translation
29 - Male tissue bacterial defense
30 - Housekeeping structural
31 - Housekeeping uncharacterized
32 - Transport
33 - Lens
34 - Prostate uncharacterized
35 - Low abundant uncharacterized
36 - Receptors uncharacterized
37 - Olfactory bulb
38 - Lung and thyroid development
39 - Kidney transport
40 - Testis
41 - Low abundant uncharacterized
42 - Low abundant uncharacterized
43 - Breast uncharacterized
44 - Housekeeping
45 - Thymus uncharacterized
46 - Skeletal muscle contraction
47 - Spleen uncharacterized
48 - Low abundant uncharacterized
49 - Heart contraction
50 - Muscle contraction
51 - Liver and kidney
52 - Housekeeping
53 - Housekeeping mitochondrial
54 - Interferons
55 - Low abundant uncharacterized
56 - Low abundant uncharacterized
57 - Skin
58 - Immune cells
59 - Squamous epithelium
60 - Not detected
61 - Enzymes and secretion
62 - Squamous epithelium
63 - Small intestine
64 - Gastrointestinal
65 - Epithelium
66 - Housekeeping mRNA
67 - Gastrointestinal
68 - Housekeeping protein processing
69 - Housekeeping
70 - Housekeeping
71 - Housekeeping regulation
72 - Digestive and respiratory defense
73 - Housekeeping cell cycle
74 - Extracellular matrix
75 - Housekeeping
76 - Housekeeping regulation
77 - Housekeeping defense
78 - Lymphoid T cells
79 - Lymphoid myeloid
80 - Heart uncharacterized
81 - Vasculature and connective tissue
82 - Lymphoid B cell
83 - Not detected
84 - Epithelium transcription regulation
Tissue group
Any
Adipose tissue
Adrenal gland
Aorta
Bone marrow
Brain
Breast
Cartilage
Cervix
Choroid plexus
Cornea
Ductus deferens
Dura mater
Endometrium
Epididymis
Esophagus
Fallopian tube
Gallbladder
Heart
Kidney
Large intestine
Lens
Liver
Lung
Lymphoid tissue
Male glands
Mesothelial tissue
Mouth
Ovary
Penis
Pineal gland
Pituitary gland
Retina
Salivary gland
Skeletal muscle
Skin
Small intestine
Smooth muscle
Stomach
Synovial tissue
Testis
Thyroid gland
Upper respiratory system
Urinary bladder
Vagus nerve
Category
Tissue enriched
Group enriched
Tissue enhanced
Low tissue specificity
Not detected
Detected in all
Detected in many
Detected in some
Detected in single
Is highest expressed
Brain region
Any
Amygdala
Basal ganglia
Cerebellum
Cerebral cortex
Corpus callosum
Hippocampal formation
Hypothalamus
Midbrain
Olfactory region
Pituitary gland
Pons and medulla
Retina
Spinal cord
Thalamus
Category
Region enriched
Group enriched
Region enhanced
Low region specificity
Not detected
Detected in all
Detected in many
Detected in some
Detected in single
Is highest expressed
Column
Gene
Position
Tissue specific score
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THE PIG PROTEOME
THE PIG ATLAS
TISSUE SPECIFIC PROTEOME
UMAP GENE CLUSTERING
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16894 GENES FOUND
Gene
Gene
i
Gene name, if available.
Gene synonym (Human ortholog)
Ensembl gene id
Ensembl gene id (Proteincoding human ortholog)
Gene description
Uniprot accession (Human ortholog)
Chromosome
Chromosome position
Related human disease
RNA category pig
RNA pig tissue group specificity
RNA pig tissue group distribution
RNA pig tissue group specificity score
RNA pig tissue group specific NX
RNA pig brain regional specificity
RNA pig brain regional distribution
RNA pig brain regional specificity score
RNA pig brain regional specific pTPM
Annotation
UMAP cluster
Within tissue variation
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Select data columns:
Gene
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Gene
i
Gene name, if available.
Gene synonym (Human ortholog)
Ensembl gene id
Ensembl gene id (Proteincoding human ortholog)
Gene description
Uniprot accession (Human ortholog)
Chromosome
Chromosome position
Related human disease
RNA category pig
Expand
RNA pig tissue group specificity
RNA pig tissue group distribution
RNA pig tissue group specificity score
RNA pig tissue group specific NX
RNA pig brain regional specificity
RNA pig brain regional distribution
RNA pig brain regional specificity score
RNA pig brain regional specific pTPM
Annotation
Expand
UMAP cluster
Within tissue variation
Pig Tissue RNA
Expand
Abdominal adipose tissue [NX]
Adrenal gland [NX]
Amygdala [NX]
Aorta [NX]
Bone marrow [NX]
Breast [NX]
Bronchus [NX]
Bulbourethral gland [NX]
Caudate [NX]
Cecum [NX]
Cerebellum [NX]
Cervix [NX]
Choroid plexus [NX]
Cingulate cortex [NX]
Colon [NX]
Cornea [NX]
Corpus callosum [NX]
Dorsal hippocampus [NX]
Dorsal spinal cord [NX]
Ductus deferens [NX]
Duodenum [NX]
Dura mater [NX]
Ear cartilage [NX]
Endometrium 1 [NX]
Entorhinal cortex [NX]
Epididymis [NX]
Esophagus [NX]
Facial adipose tissue [NX]
Fallopian tube [NX]
Gallbladder [NX]
Heart atrium [NX]
Heart valve [NX]
Heart wall [NX]
Hypothalamus [NX]
Ileum [NX]
Insular cortex [NX]
Jejunum [NX]
Joint cartilage [NX]
Kidney (cortex) [NX]
Kidney (medulla) [NX]
Larynx [NX]
Lens [NX]
Lip [NX]
Liver [NX]
Lung [NX]
Lymph node [NX]
Medulla [NX]
Midbrain [NX]
Motor cortex [NX]
Nasopharynx epithelium [NX]
Occipital cortex [NX]
Olfactory bulb [NX]
Olfactory epithelium [NX]
Oral mucosa [NX]
Ovary [NX]
Penis [NX]
Periaqueductal gray [NX]
Peritoneum [NX]
Pineal gland [NX]
Pituitary gland [NX]
Pleura [NX]
Pons [NX]
Prefrontal cortex [NX]
Prostate [NX]
Putamen [NX]
Rectum [NX]
Retina [NX]
Retrosplenial cortex [NX]
Salivary gland [NX]
Seminal vesicle [NX]
Septum [NX]
Skeletal muscle [NX]
Skin (back) [NX]
Skin (groin) [NX]
Smooth muscle (intestine) [NX]
Somatosensory cortex [NX]
Spleen [NX]
Stomach (lower) [NX]
Stomach (upper) [NX]
Subcutaneous adipose tissue [NX]
Subiculum [NX]
Substantia nigra [NX]
Superior colliculi [NX]
Synovial tissue [NX]
Temporal cortex [NX]
Testis [NX]
Thalamus [NX]
Thymus [NX]
Thyroid gland [NX]
Tongue [NX]
Tonsil [NX]
Trachea [NX]
Urethral gland [NX]
Urinary bladder [NX]
Vagus nerve [NX]
Ventral hippocampus [NX]
Ventral pallidum [NX]
Ventral spinal cord [NX]
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Gene
i
Gene name, if available.
Ensembl
x
Human ortholog
x
Gene description
x
RNA pig tissue group specificity
x
RNA pig tissue group distribution
x
RNA pig tissue group specific NX
x
IRX5
ENSSSCG00000032145
ENSG00000176842
Iroquois homeobox 5
Tissue enhanced
Detected in many
breast:
32.9
male glands:
51.4
ISCA2
ENSSSCG00000002367
ENSG00000165898
Iron-sulfur cluster assembly 2
Tissue enhanced
Detected in all
epididymis:
41.7
ISCU
ENSSSCG00000023380
ENSG00000136003
Iron-sulfur cluster assembly enzyme
Low tissue specificity
Detected in all
ISG12(A)
ENSSSCG00000035297
ENSG00000165949
Uncharacterized protein LOC100153902
Low tissue specificity
Detected in all
ISG15
ENSSSCG00000040575
ENSG00000187608
ISG15 ubiquitin-like modifier
Low tissue specificity
Detected in many
ISG20
ENSSSCG00000024867
ENSG00000172183
Interferon stimulated exonuclease gene 20
Tissue enhanced
Detected in many
large intestine:
15.5
small intestine:
26.5
stomach:
18.2
upper respiratory system:
15.9
ISG20L2
ENSSSCG00000006471
ENSG00000143319
Interferon stimulated exonuclease gene 20 like 2
Tissue enriched
Detected in all
testis:
88.7
ISL1
ENSSSCG00000016883
ENSG00000016082
ISL LIM homeobox 1
Tissue enhanced
Detected in many
male glands:
16.6
penis:
36.4
ISLR
ENSSSCG00000001910
ENSG00000129009
Immunoglobulin superfamily containing leucine rich repeat
Tissue enhanced
Detected in many
cartilage:
98.7
vagus nerve:
73.3
ISLR2
ENSSSCG00000036011
ENSG00000167178
Immunoglobulin superfamily containing leucine rich repeat 2
Tissue enhanced
Detected in many
brain:
18.8
mesothelial tissue:
13.3
vagus nerve:
15.9
ISM1
ENSSSCG00000007073
ENSG00000101230
Isthmin 1
Tissue enhanced
Detected in many
cartilage:
84.7
ISOC1
ENSSSCG00000014258
ENSG00000066583
Isochorismatase domain containing 1
Tissue enhanced
Detected in all
male glands:
35.7
ISOC2
ENSSSCG00000003289
ENSG00000063241
Isochorismatase domain containing 2
Low tissue specificity
Detected in all
ISPD
ENSSSCG00000015358
ENSG00000214960
Isoprenoid synthase domain containing
Tissue enhanced
Detected in all
choroid plexus:
28.9
ISYNA1
ENSSSCG00000040524
ENSG00000105655
Inositol-3-phosphate synthase 1
Tissue enhanced
Detected in many
choroid plexus:
135.7
testis:
64.6
ITCH
ENSSSCG00000007280
ENSG00000078747
Itchy E3 ubiquitin protein ligase
Low tissue specificity
Detected in all
ITFG1
ENSSSCG00000033527
ENSG00000129636
Integrin alpha FG-GAP repeat containing 1
Low tissue specificity
Detected in all
ITFG2
ENSSSCG00000000742
ENSG00000111203
Integrin alpha FG-GAP repeat containing 2
Low tissue specificity
Detected in all
ITGA1
ENSSSCG00000016885
ENSG00000213949
Integrin subunit alpha 1
Tissue enhanced
Detected in many
cartilage:
56.4
smooth muscle:
85.1
ITGA10
ENSSSCG00000006687
ENSG00000143127
Integrin subunit alpha 10
Tissue enriched
Detected in all
cartilage:
55.2
ITGA11
ENSSSCG00000004961
ENSG00000137809
Integrin subunit alpha 11
Tissue enhanced
Detected in many
dura mater:
26.8
ITGA2
ENSSSCG00000016887
ENSG00000164171
Integrin alpha-2 precursor
Low tissue specificity
Detected in many
ITGA2B
ENSSSCG00000017357
ENSG00000186566
Integrin alpha-IIb precursor
Low tissue specificity
Detected in all
ITGA3
ENSSSCG00000017578
ENSG00000005884
Integrin subunit alpha 3
Low tissue specificity
Detected in many
ITGA4
ENSSSCG00000016009
ENSG00000115232
Integrin subunit alpha 4
Tissue enriched
Detected in many
lymphoid tissue:
63.2
ITGA5
ENSSSCG00000000293
ENSG00000161638
Integrin subunit alpha 5
Tissue enhanced
Detected in many
ovary:
54.9
ITGA6
ENSSSCG00000015955
ENSG00000091409
Integrin subunit alpha 6
Low tissue specificity
Detected in all
ITGA7
ENSSSCG00000036237
ENSG00000135424
Integrin subunit alpha 7
Tissue enhanced
Detected in many
adipose tissue:
76.7
ITGA8
ENSSSCG00000011046
ENSG00000077943
Integrin subunit alpha 8
Tissue enhanced
Detected in many
cervix:
61.7
endometrium:
34.7
fallopian tube:
40.9
ITGA9
ENSSSCG00000011245
ENSG00000144668
Integrin subunit alpha 9
Tissue enhanced
Detected in many
liver:
66.6
lymphoid tissue:
63.5
ITGAE
ENSSSCG00000017869
ENSG00000083457
Integrin subunit alpha E
Tissue enhanced
Detected in many
lens:
57.9
lymphoid tissue:
25.9
ITGAL
ENSSSCG00000007797
ENSG00000005844
Integrin alpha-L precursor
Tissue enhanced
Detected in many
lymphoid tissue:
49.4
stomach:
27.1
ITGAV
ENSSSCG00000016027
ENSG00000138448
Integrin alpha-V precursor
Tissue enhanced
Detected in all
ovary:
65.8
ITGAX
ENSSSCG00000007754
ENSG00000140678
Integrin subunit alpha X
Tissue enhanced
Detected in all
lymphoid tissue:
83.4
ITGB1
ENSSSCG00000011101
ENSG00000150093
Integrin beta-1 precursor
Low tissue specificity
Detected in all
ITGB1BP1
ENSSSCG00000029313
ENSG00000119185
Integrin subunit beta 1 binding protein 1
Low tissue specificity
Detected in all
ITGB1BP2
ENSSSCG00000022209
ENSG00000147166
Integrin beta-1-binding protein 2
Group enriched
Detected in many
heart:
33.1
skeletal muscle:
27.7
smooth muscle:
20.9
ITGB2
ENSSSCG00000025133
ENSG00000160255
Integrin beta-2 precursor
Tissue enhanced
Detected in all
lymphoid tissue:
71.8
ITGB3
ENSSSCG00000017306
ENSG00000259207
Integrin beta-3 precursor
Tissue enhanced
Detected in all
dura mater:
31.3
ovary:
30.1
ITGB4
ENSSSCG00000017204
ENSG00000132470
Integrin subunit beta 4
Tissue enhanced
Detected in many
vagus nerve:
116.2
ITGB5
ENSSSCG00000037905
ENSG00000082781
Integrin beta-5 precursor
Low tissue specificity
Detected in all
ITGB6
ENSSSCG00000015886
ENSG00000115221
Integrin beta-6 precursor
Tissue enhanced
Detected in many
epididymis:
22.6
heart:
30.6
skeletal muscle:
26.4
ITGB7
ENSSSCG00000000257
ENSG00000139626
Integrin subunit beta 7
Tissue enhanced
Detected in many
lymphoid tissue:
36.0
stomach:
32.9
ITGB8
ENSSSCG00000015375
ENSG00000105855
Integrin beta-8 precursor
Tissue enhanced
Detected in many
brain:
49.6
vagus nerve:
60.5
ITGBL1
ENSSSCG00000009526
ENSG00000198542
Integrin subunit beta like 1
Tissue enhanced
Detected in many
aorta:
29.7
cornea:
42.0
dura mater:
31.8
vagus nerve:
32.9
ITIH1
ENSSSCG00000011450
ENSG00000055957
Inter-alpha-trypsin inhibitor heavy chain 1
Tissue enriched
Detected in all
liver:
234.9
ITIH4
ENSSSCG00000011453
ENSG00000055955
Inter-alpha-trypsin inhibitor heavy chain H4 precursor
Tissue enhanced
Detected in many
cervix:
61.4
liver:
161.3
ITIH5
ENSSSCG00000011129
ENSG00000123243
Inter-alpha-trypsin inhibitor heavy chain family member 5
Low tissue specificity
Detected in all
ITK
ENSSSCG00000038003
ENSG00000113263
IL2 inducible T cell kinase
Tissue enriched
Detected in many
lymphoid tissue:
43.4
ITM2A
ENSSSCG00000012448
ENSG00000078596
Integral membrane protein 2A
Low tissue specificity
Detected in all
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