Gene "Gene synonym (Human)" Ensembl "Human ortholog" "Gene description" "Uniprot (Human)" Chromosome Position "Related human disease" "RNA pig tissue group specificity" "RNA pig tissue group distribution" "RNA pig tissue group specificity score" "RNA pig tissue group specific NX" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific pTPM" "UMAP cluster" "Within tissue variation" "Pig Tissue RNA - abdominal adipose tissue [NX]" "Pig Tissue RNA - adrenal gland [NX]" "Pig Tissue RNA - amygdala [NX]" "Pig Tissue RNA - aorta [NX]" "Pig Tissue RNA - bone marrow [NX]" "Pig Tissue RNA - breast [NX]" "Pig Tissue RNA - bronchus [NX]" "Pig Tissue RNA - bulbourethral gland [NX]" "Pig Tissue RNA - caudate [NX]" "Pig Tissue RNA - cecum [NX]" "Pig Tissue RNA - cerebellum [NX]" "Pig Tissue RNA - cervix [NX]" "Pig Tissue RNA - choroid plexus [NX]" "Pig Tissue RNA - cingulate cortex [NX]" "Pig Tissue RNA - colon [NX]" "Pig Tissue RNA - cornea [NX]" "Pig Tissue RNA - corpus callosum [NX]" "Pig Tissue RNA - dorsal hippocampus [NX]" "Pig Tissue RNA - dorsal spinal cord [NX]" "Pig Tissue RNA - ductus deferens [NX]" "Pig Tissue RNA - duodenum [NX]" "Pig Tissue RNA - dura mater [NX]" "Pig Tissue RNA - ear cartilage [NX]" "Pig Tissue RNA - endometrium 1 [NX]" "Pig Tissue RNA - entorhinal cortex [NX]" "Pig Tissue RNA - epididymis [NX]" "Pig Tissue RNA - esophagus [NX]" "Pig Tissue RNA - facial adipose tissue [NX]" "Pig Tissue RNA - fallopian tube [NX]" "Pig Tissue RNA - gallbladder [NX]" "Pig Tissue RNA - heart atrium [NX]" "Pig Tissue RNA - heart valve [NX]" "Pig Tissue RNA - heart wall [NX]" "Pig Tissue RNA - hypothalamus [NX]" "Pig Tissue RNA - ileum [NX]" "Pig Tissue RNA - insular cortex [NX]" "Pig Tissue RNA - jejunum [NX]" "Pig Tissue RNA - joint cartilage [NX]" "Pig Tissue RNA - kidney (cortex) [NX]" "Pig Tissue RNA - kidney (medulla) [NX]" "Pig Tissue RNA - larynx [NX]" "Pig Tissue RNA - lens [NX]" "Pig Tissue RNA - lip [NX]" "Pig Tissue RNA - liver [NX]" "Pig Tissue RNA - lung [NX]" "Pig Tissue RNA - lymph node [NX]" "Pig Tissue RNA - medulla [NX]" "Pig Tissue RNA - midbrain [NX]" "Pig Tissue RNA - motor cortex [NX]" "Pig Tissue RNA - nasopharynx epithelium [NX]" "Pig Tissue RNA - occipital cortex [NX]" "Pig Tissue RNA - olfactory bulb [NX]" "Pig Tissue RNA - olfactory epithelium [NX]" "Pig Tissue RNA - oral mucosa [NX]" "Pig Tissue RNA - ovary [NX]" "Pig Tissue RNA - penis [NX]" "Pig Tissue RNA - periaqueductal gray [NX]" "Pig Tissue RNA - peritoneum [NX]" "Pig Tissue RNA - pineal gland [NX]" "Pig Tissue RNA - pituitary gland [NX]" "Pig Tissue RNA - pleura [NX]" "Pig Tissue RNA - pons [NX]" "Pig Tissue RNA - prefrontal cortex [NX]" "Pig Tissue RNA - prostate [NX]" "Pig Tissue RNA - putamen [NX]" "Pig Tissue RNA - rectum [NX]" "Pig Tissue RNA - retina [NX]" "Pig Tissue RNA - retrosplenial cortex [NX]" "Pig Tissue RNA - salivary gland [NX]" "Pig Tissue RNA - seminal vesicle [NX]" "Pig Tissue RNA - septum [NX]" "Pig Tissue RNA - skeletal muscle [NX]" "Pig Tissue RNA - skin (back) [NX]" "Pig Tissue RNA - skin (groin) [NX]" "Pig Tissue RNA - smooth muscle (intestine) [NX]" "Pig Tissue RNA - somatosensory cortex [NX]" "Pig Tissue RNA - spleen [NX]" "Pig Tissue RNA - stomach (lower) [NX]" "Pig Tissue RNA - stomach (upper) [NX]" "Pig Tissue RNA - subcutaneous adipose tissue [NX]" "Pig Tissue RNA - subiculum [NX]" "Pig Tissue RNA - substantia nigra [NX]" "Pig Tissue RNA - superior colliculi [NX]" "Pig Tissue RNA - synovial tissue [NX]" "Pig Tissue RNA - temporal cortex [NX]" "Pig Tissue RNA - testis [NX]" "Pig Tissue RNA - thalamus [NX]" "Pig Tissue RNA - thymus [NX]" "Pig Tissue RNA - thyroid gland [NX]" "Pig Tissue RNA - tongue [NX]" "Pig Tissue RNA - tonsil [NX]" "Pig Tissue RNA - trachea [NX]" "Pig Tissue RNA - urethral gland [NX]" "Pig Tissue RNA - urinary bladder [NX]" "Pig Tissue RNA - vagus nerve [NX]" "Pig Tissue RNA - ventral hippocampus [NX]" "Pig Tissue RNA - ventral pallidum [NX]" "Pig Tissue RNA - ventral spinal cord [NX]" AAAS ENSSSCG00000000268 "one2one with ENSG00000094914" "Aladin WD repeat nucleoporin" Q9NRG9 5 18521628-18537864 "Human disease related genes" "Low tissue specificity" "Detected in all" "Low region specificity" "Detected in all" "Cluster 44 - Housekeeping" "Not variable" 7.5 7.8 10.9 2.4 5.3 8.7 12.6 5.1 8.9 13.4 19.0 12.4 18.5 10.0 13.3 19.5 13.9 8.7 8.1 11.4 12.0 13.9 8.0 14.7 8.4 9.0 15.0 5.4 16.0 10.0 4.8 3.8 3.6 9.8 6.3 9.8 7.1 1.1 8.5 14.9 11.3 1.9 12.8 5.1 12.8 13.8 7.9 7.5 6.9 7.8 7.2 17.9 12.8 10.7 9.1 7.5 10.7 2.4 14.8 14.2 4.6 6.3 7.5 10.7 6.6 11.5 28.8 9.7 4.9 8.4 9.5 5.3 9.5 6.4 8.7 7.3 9.1 6.2 4.6 4.6 9.5 9.2 7.2 5.9 8.6 12.8 7.0 33.4 18.0 10.0 16.2 13.1 8.0 8.8 13.7 9.5 9.0 7.1 ABCC8 "ABC36, HHF1, HI, HRINS, MRP8, PHHI, SUR, SUR1, TNDM2" ENSSSCG00000013378 "one2one with ENSG00000006071" "ATP binding cassette subfamily C member 8" Q09428 2 41666909-41756703 "Human disease related genes" "Group enriched" "Detected in some" 8 "brain: 17.6;vagus nerve: 57.7" "Low region specificity" "Detected in all" "Cluster 4 - Brain development" "Variable (brain, heart)" 0.3 0.6 5.3 0.6 0.2 1.7 0.6 0.0 7.7 0.3 10.5 0.2 0.1 18.6 0.5 0.3 2.4 7.9 8.6 1.5 0.9 1.9 1.3 0.2 17.1 0.0 0.3 0.1 0.1 0.1 3.9 1.6 0.2 4.8 0.4 14.8 0.7 0.0 0.1 0.1 0.2 0.1 3.1 0.0 0.6 0.1 4.2 4.2 15.6 0.1 29.2 8.4 0.2 1.0 0.7 4.0 4.0 0.2 0.7 0.3 1.8 4.8 14.8 0.0 5.7 0.8 9.0 16.0 0.0 0.0 3.8 0.2 0.5 0.8 0.6 32.9 0.0 0.6 0.1 0.4 8.4 3.7 5.0 0.6 16.3 0.4 5.5 0.1 3.7 1.7 0.1 0.1 0.1 0.1 131.2 7.6 5.7 2.4 ACE "ACE1, CD143, DCP1" ENSSSCG00000017296 "one2many with ENSG00000159640" "Angiotensin-converting enzyme isoform 1 precursor " P12821 12 15394491-15414632 "Human disease related genes" "Tissue enhanced" "Detected in many" "testis: 102.1" "Low region specificity" "Detected in all" "Cluster 81 - Vasculature and connective tissue" "Variable (cartilage, kidney, lymphoid tissue, small intestine)" 33.9 33.3 8.2 13.3 19.6 37.3 50.2 1.8 13.6 4.3 7.3 22.5 7.0 9.6 3.9 2.5 10.4 6.6 17.3 18.0 6.2 18.1 36.4 24.1 9.0 4.9 10.0 39.6 41.5 34.4 14.1 10.3 9.2 12.7 30.6 10.2 21.9 0.1 63.3 21.3 8.9 0.0 36.4 0.9 58.5 5.6 13.0 12.9 8.7 8.5 8.2 9.9 9.4 19.7 20.7 35.8 10.4 9.1 26.3 16.2 32.0 12.9 8.2 2.7 13.6 6.0 3.9 8.6 1.4 3.7 10.2 13.8 15.0 13.6 9.9 9.8 9.9 3.9 3.2 24.4 8.1 16.1 14.2 16.1 9.3 373.3 13.3 1.3 8.3 20.5 3.0 14.5 6.2 11.3 41.7 8.7 10.0 13.4 ADAMTS9 KIAA1312 ENSSSCG00000011496 "one2one with ENSG00000163638" "ADAM metallopeptidase with thrombospondin type 1 motif 9" Q9P2N4 13 46033758-46207006 "Human disease related genes" "Tissue enhanced" "Detected in many" "mesothelial tissue: 68.1" "Low region specificity" "Detected in many" "Cluster 81 - Vasculature and connective tissue" "Variable (brain, cartilage)" 28.2 10.1 3.4 35.0 65.0 29.2 24.7 8.1 1.4 5.3 7.6 65.3 4.2 2.4 4.9 7.1 4.2 3.2 16.7 36.2 4.3 66.1 39.1 70.1 3.0 7.7 10.6 43.2 11.7 30.0 10.8 12.9 12.2 4.5 3.8 1.9 5.7 1.6 13.3 10.2 12.7 0.0 36.5 2.4 22.8 5.9 10.6 7.9 1.9 9.0 1.5 4.3 15.8 22.9 75.2 40.1 8.4 12.6 19.0 17.6 99.7 4.7 1.9 3.5 0.9 6.9 0.8 2.3 2.2 2.7 2.2 17.4 18.7 16.7 19.5 1.9 6.4 4.9 4.8 37.2 3.0 11.3 5.3 29.6 3.3 9.4 4.3 3.9 8.0 14.7 6.0 19.4 8.8 28.9 46.0 4.4 1.9 15.6 ADCY3 AC3 ENSSSCG00000008578 "one2one with ENSG00000138031" "Adenylate cyclase 3" O60266 3 113876339-113985479 "Human disease related genes" "Tissue enhanced" "Detected in all" "ovary: 38.6" "Low region specificity" "Detected in all" "Cluster 5 - Intracellular signalling" "Variable (brain)" 15.6 6.6 11.3 3.7 2.5 9.6 8.8 5.4 24.4 6.0 11.4 10.4 12.6 9.8 6.3 8.9 5.7 10.0 8.6 13.6 4.7 12.1 9.1 8.2 9.3 5.3 6.6 8.7 10.1 5.9 5.4 2.9 2.1 11.4 2.8 9.2 3.5 4.8 3.6 5.8 6.6 1.1 12.4 2.4 9.4 4.6 7.7 8.7 7.8 5.4 8.3 11.3 7.3 9.5 49.0 17.5 9.9 7.2 10.7 9.6 11.1 10.0 8.1 5.6 14.5 5.7 13.8 9.1 2.2 3.1 17.0 3.0 5.6 5.8 4.5 9.5 3.4 3.6 3.1 4.4 10.1 8.0 10.0 11.2 9.7 9.4 9.7 14.4 8.0 6.5 5.8 11.8 4.7 13.6 16.5 10.9 18.1 5.3 ADRB2 "ADRB2R, ADRBR, B2AR, BAR" ENSSSCG00000038598 "one2one with ENSG00000169252" "Beta-2 adrenergic receptor " P07550 2 150033550-150035599 "Human disease related genes" "Low tissue specificity" "Detected in many" "Low region specificity" "Detected in all" "Cluster 81 - Vasculature and connective tissue" "Variable (brain, lymphoid tissue, male glands, mesothelial tissue)" 13.4 1.0 3.4 5.7 9.1 6.6 15.8 20.2 2.8 2.4 22.0 9.2 1.2 2.7 3.4 16.0 4.7 2.8 6.5 4.4 1.5 8.7 4.0 13.3 2.6 0.8 6.7 14.6 3.0 7.9 4.2 3.9 3.0 5.3 1.1 3.1 1.9 0.5 0.5 2.1 8.6 0.0 12.8 7.8 15.5 3.4 5.0 3.8 2.0 7.0 2.3 2.7 15.4 11.8 3.6 4.1 5.1 2.0 3.8 0.6 16.8 4.2 2.5 1.4 2.9 3.3 0.2 2.6 1.2 6.8 4.7 16.7 2.3 1.3 4.8 2.4 9.1 2.4 5.3 7.7 3.1 5.9 4.2 11.0 2.6 5.9 3.9 1.5 1.7 7.6 2.8 10.1 3.7 11.6 9.6 3.3 3.2 5.0 ADRB3 ENSSSCG00000015821 "one2one with ENSG00000188778" "Beta-3 adrenergic receptor " P13945 15 48475144-48479541 "Human disease related genes" "Group enriched" "Detected in some" 9 "lymphoid tissue: 28.2;smooth muscle: 7.3" "Not detected" "Not detected" "Cluster 47 - Spleen uncharacterized" "Variable (lymphoid tissue)" 0.0 0.0 0.0 0.0 0.0 0.2 1.3 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.0 0.0 1.0 0.0 0.0 0.1 0.0 1.8 1.1 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.6 0.0 16.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.1 0.0 1.0 0.1 0.0 0.2 0.2 0.0 0.0 0.0 AGRP "Agrt, ART, ASIP2" ENSSSCG00000002775 "one2one with ENSG00000159723" "Agouti-related protein " O00253 6 28132615-28133661 "Human disease related genes" "Group enriched" "Detected in some" 5 "brain: 9.1;pineal gland: 7.7;pituitary gland: 2.4" "Region enhanced" "Detected in many" "hypothalamus: 9.1" "Cluster 8 - Neurohormonal" "Not variable" 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.2 0.8 0.1 0.0 0.3 0.2 0.1 0.0 3.9 1.2 0.0 0.2 0.2 0.0 0.3 0.3 0.6 0.1 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.4 0.5 0.0 0.6 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.3 0.0 AIP "ARA9, FKBP16, XAP2" ENSSSCG00000012904 "one2one with ENSG00000110711" "Aryl hydrocarbon receptor interacting protein" O00170 2 5042125-5048963 "Human disease related genes" "Low tissue specificity" "Detected in all" "Low region specificity" "Detected in all" "Cluster 4 - Brain development" "Not variable" 22.8 13.5 22.9 9.3 16.8 11.8 21.0 14.9 27.1 18.2 38.1 28.2 27.8 26.6 17.7 20.8 28.8 28.0 29.1 24.3 12.8 26.3 11.2 20.4 25.5 6.9 16.0 18.0 14.2 24.0 8.1 6.8 6.2 30.9 9.1 22.7 12.5 6.5 8.9 22.1 12.3 8.8 13.8 4.3 24.1 33.5 28.9 32.1 22.9 10.1 24.4 34.6 20.0 13.5 16.9 23.8 27.4 7.3 48.8 27.2 13.7 30.0 21.7 8.6 21.3 17.2 40.9 24.0 4.5 8.0 31.4 7.9 9.1 7.5 23.2 30.4 17.6 10.6 14.4 12.1 26.6 27.6 37.6 15.8 26.8 12.2 32.3 35.5 16.9 8.7 27.1 17.5 7.7 19.4 27.8 28.7 26.2 25.1 APC "DP2, DP2.5, DP3, PPP1R46" ENSSSCG00000014207 "one2one with ENSG00000134982" "Adenomatous polyposis coli protein " P25054 2 116912626-117097925 "Human disease related genes" "Tissue enhanced" "Detected in all" "brain: 50.8" "Low region specificity" "Detected in all" "Cluster 1 - Brain neurotransmission" "Not variable" 26.9 28.9 144.3 8.4 21.5 19.1 31.7 38.4 102.3 26.8 120.8 27.8 33.0 187.1 32.2 19.9 158.0 161.8 101.6 21.4 26.5 38.3 13.0 25.1 183.2 14.4 28.5 18.7 22.5 22.6 14.2 12.1 10.0 109.0 21.6 175.3 24.6 2.4 22.0 59.0 21.2 11.9 27.1 18.7 34.2 30.4 109.6 118.5 173.3 19.9 177.2 223.6 24.5 22.6 35.8 23.4 111.6 6.0 96.4 61.2 10.5 101.9 171.2 16.7 92.8 34.2 75.8 182.4 14.9 18.8 117.4 17.2 16.3 12.5 29.6 184.4 24.0 15.2 15.6 14.2 174.2 111.8 116.0 20.8 182.6 26.8 119.0 46.3 34.0 23.7 37.7 28.9 18.4 21.6 36.2 150.6 110.0 108.6 APOA5 "APOA-V, RAP3" ENSSSCG00000015067 "one2one with ENSG00000110243" "Apolipoprotein A-V precursor " Q6Q788 9 44167425-44180885 "Human disease related genes" "Tissue enriched" "Detected in some" 17 "liver: 64.0" "Not detected" "Not detected" "Cluster 51 - Liver and kidney" "Variable (kidney)" 0.3 0.2 0.1 0.0 0.1 0.2 0.3 0.5 0.0 0.1 0.1 0.1 0.1 0.1 0.2 0.2 0.2 0.1 0.1 0.0 0.3 0.1 0.1 0.5 0.1 0.1 0.1 0.2 0.4 1.5 0.0 0.0 0.0 0.2 0.1 0.1 0.1 0.0 4.3 0.2 0.2 0.0 0.3 50.9 0.2 0.2 0.2 0.2 0.0 0.3 0.1 0.1 0.5 0.1 0.1 0.2 0.1 0.0 0.0 0.1 0.1 0.2 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.2 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.2 0.1 0.1 4.3 0.2 0.4 0.2 0.1 0.1 0.4 0.0 0.1 0.2 0.1 0.1 0.1 APOC2 ENSSSCG00000003086 "one2one with ENSG00000234906" "Apolipoprotein C-II precursor " P02655 6 51404280-51406445 "Human disease related genes" "Tissue enriched" "Detected in some" 51 "liver: 223.8" "Not detected" "Not detected" "Cluster 51 - Liver and kidney" "Not variable" 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 623.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 APPL1 APPL ENSSSCG00000032357 "one2one with ENSG00000157500" "DCC-interacting protein 13-alpha " Q9UKG1 13 39088704-39129433 "Human disease related genes" "Low tissue specificity" "Detected in all" "Low region specificity" "Detected in all" "Cluster 10 - Housekeeping transcription" "Not variable" 37.7 21.6 57.9 14.1 22.6 27.2 33.0 35.7 52.5 21.7 101.8 56.8 35.4 61.3 26.1 43.4 85.0 72.8 73.8 34.2 25.5 61.6 18.6 44.8 58.6 15.0 36.7 19.2 76.8 31.4 14.4 10.8 12.5 69.5 10.9 50.2 20.8 7.1 15.1 40.3 24.4 11.1 42.9 7.4 47.9 32.3 64.4 63.9 50.5 24.2 51.9 91.1 32.5 34.5 43.6 26.7 71.0 13.2 125.2 126.4 18.4 59.3 52.7 12.5 47.5 25.0 113.7 57.7 13.0 16.1 71.0 28.0 14.3 14.0 35.3 59.5 21.3 9.9 5.6 17.3 69.3 68.7 65.0 29.0 58.5 30.1 60.0 51.8 40.5 37.6 36.3 36.5 12.4 27.3 61.2 71.0 58.8 66.6 ARMC5 FLJ13063 ENSSSCG00000025245 "one2one with ENSG00000140691" "Armadillo repeat containing 5" Q96C12 3 17100897-17108981 "Human disease related genes" "Low tissue specificity" "Detected in all" "Low region specificity" "Detected in all" "Cluster 70 - Housekeeping" "Not variable" 4.3 4.6 3.0 1.2 1.8 2.1 3.8 3.0 3.3 2.7 4.7 7.5 7.4 3.2 2.4 5.1 3.9 3.4 3.4 4.4 2.6 5.5 2.7 6.6 3.1 2.4 3.8 3.1 4.3 4.8 1.4 1.3 0.9 4.1 1.5 3.0 1.9 1.3 1.9 4.3 2.5 1.2 2.9 1.5 4.2 3.2 3.6 3.2 2.7 2.3 2.8 4.2 4.4 2.7 5.0 3.4 4.2 1.6 3.7 5.2 2.9 3.3 2.7 3.3 2.4 2.9 4.6 2.9 1.7 3.3 3.5 1.4 2.1 0.9 2.7 3.4 2.3 2.0 2.2 1.7 3.6 3.8 4.2 3.3 3.2 3.6 3.6 5.0 3.5 1.8 4.0 3.6 2.4 3.6 4.2 4.0 2.9 3.3 ATP1A1 ENSSSCG00000006740 "one2one with ENSG00000163399" "Sodium/potassium-transporting ATPase subunit alpha-1 precursor " P05023 4 104349185-104384646 "Human disease related genes" "Tissue enhanced" "Detected in all" "kidney: 127.3;male glands: 141.9" "Low region specificity" "Detected in all" "Cluster 5 - Intracellular signalling" "Variable (brain, male glands)" 126.1 321.1 145.9 31.2 56.3 66.4 136.1 583.5 250.4 349.6 473.0 84.2 272.4 299.7 338.7 289.1 137.6 296.5 170.2 82.5 187.4 118.6 51.9 363.8 302.2 68.1 157.1 46.8 415.3 345.8 67.2 55.1 114.4 134.0 158.2 217.0 117.3 16.2 469.2 1035.5 172.9 65.2 86.7 28.6 182.9 44.9 180.2 218.0 252.8 222.6 380.7 439.1 145.8 116.3 272.2 76.5 126.9 42.1 225.9 241.9 64.5 183.4 274.0 375.7 192.6 255.7 195.6 245.6 257.0 65.9 178.8 14.9 56.8 26.4 41.6 476.9 29.3 93.7 96.6 29.7 183.6 149.0 217.6 90.1 319.3 60.7 201.6 81.2 567.8 71.0 53.6 178.0 583.7 57.4 75.8 265.5 205.4 194.0 ATP2B3 "CFAP39, CLA2, PMCA3, SCAX1" ENSSSCG00000012769 "one2one with ENSG00000067842" "ATPase plasma membrane Ca2+ transporting 3" Q16720 X 124301703-124357655 "Human disease related genes" "Group enriched" "Detected in some" 6 "adrenal gland: 25.3;brain: 25.9;choroid plexus: 33.3;ductus deferens: 15.0;pituitary gland: 13.8" "Low region specificity" "Detected in all" "Cluster 1 - Brain neurotransmission" "Variable (brain)" 0.5 38.6 22.7 0.1 0.1 0.1 0.4 3.5 17.0 0.2 77.0 0.4 87.1 31.8 0.3 0.2 3.4 53.5 5.3 30.5 0.3 1.4 0.1 1.1 29.6 4.6 0.4 0.0 0.4 0.2 0.3 0.4 0.6 11.9 0.2 28.3 0.3 0.0 4.6 7.6 0.5 0.0 0.7 1.6 0.4 0.0 12.1 15.3 29.3 0.3 34.5 25.6 0.3 1.1 2.4 0.7 11.7 0.5 10.7 40.0 0.5 15.3 27.3 0.6 12.1 0.2 13.1 30.9 0.2 2.7 14.8 2.9 0.2 0.0 0.7 41.1 0.3 0.0 0.0 0.0 26.3 10.3 21.3 1.1 30.0 1.0 18.2 0.1 0.0 1.6 0.2 0.9 1.8 0.3 1.6 50.0 17.0 5.0 AVP "ADH, ARVP" ENSSSCG00000007163 "one2one with ENSG00000101200" "Vasopressin-neurophysin 2-copeptin precursor " P01185 17 32580939-32583427 "Human disease related genes" "Tissue enriched" "Detected in some" 93 "brain: 151.7" "Group enriched" "Detected in some" 633 "basal ganglia: 151.8;hypothalamus: 144.2" "Cluster 8 - Neurohormonal" "Variable (brain)" 0.5 0.0 0.9 0.1 0.3 0.0 0.1 0.0 1.3 0.0 0.2 0.2 0.3 0.4 0.0 0.0 0.6 0.3 0.2 0.3 0.0 0.0 0.0 0.1 0.6 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 1058.2 0.0 0.3 0.0 0.0 1.8 0.0 0.0 0.0 0.2 0.0 0.1 0.2 0.5 0.5 0.5 0.0 0.8 0.8 0.0 0.0 0.0 0.3 0.2 0.0 0.1 14.0 0.2 0.4 0.3 0.0 0.3 0.0 0.8 0.6 0.0 0.5 1065.4 0.2 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.4 0.8 0.9 0.6 0.1 0.8 0.0 1.3 3.2 0.0 0.0 0.2 0.0 0.0 0.1 0.3 0.7 182.8 0.1 AVPR2 "DIR, DIR3, V2R" ENSSSCG00000012789 "one2one with ENSG00000126895" "Vasopressin V2 receptor " P30518 X 124638327-124643528 "Human disease related genes" "Tissue enhanced" "Detected in many" "ductus deferens: 10.9;kidney: 16.5;male glands: 19.8" "Region enriched" "Detected in single" 18 "cerebellum: 6.5" "Cluster 66 - Housekeeping mRNA" "Variable (brain, kidney, male glands)" 1.4 0.5 0.1 0.5 1.3 1.2 2.1 0.2 0.2 1.0 7.9 0.7 0.4 0.1 0.9 0.2 0.2 0.2 0.2 9.1 0.9 1.7 1.6 1.1 0.1 0.4 0.8 1.6 0.5 1.3 0.4 0.5 0.5 0.2 0.9 0.1 0.8 0.0 1.3 15.7 0.7 0.0 1.2 0.3 1.4 3.6 0.2 0.2 0.1 0.6 0.1 0.2 1.1 1.2 0.7 0.9 0.2 0.4 2.2 0.2 1.3 0.1 0.1 0.4 0.1 0.9 0.1 0.1 0.1 9.7 0.2 0.4 0.7 0.4 0.5 0.1 2.5 0.8 1.5 0.9 0.1 0.2 0.1 1.2 0.1 0.2 0.1 10.1 0.7 0.9 3.3 0.9 0.4 0.9 1.0 0.3 0.1 0.1 BACH2 BTBD25 ENSSSCG00000004332 "one2one with ENSG00000112182" "BTB domain and CNC homolog 2" Q9BYV9 1 57899809-58204804 "Human disease related genes" "Tissue enhanced" "Detected in many" "lymphoid tissue: 26.2" "Low region specificity" "Detected in many" "Cluster 82 - Lymphoid B cell" "Variable (lymphoid tissue, male glands)" 2.2 0.5 3.2 1.4 1.2 4.5 11.5 9.0 3.3 3.2 1.7 3.4 0.2 4.4 5.3 0.9 3.5 2.9 2.3 1.8 8.0 5.3 3.0 1.4 3.8 1.3 16.4 0.9 4.2 4.8 2.0 2.6 1.5 2.4 3.7 4.0 5.5 0.6 0.7 0.9 3.8 4.4 4.7 2.6 14.0 25.7 1.9 2.4 3.3 4.1 3.4 4.8 14.9 2.0 6.4 3.7 2.2 0.9 4.7 2.1 1.5 2.2 3.4 0.6 3.0 6.7 4.1 4.1 3.9 0.6 2.6 4.1 4.8 2.4 3.9 3.6 4.6 1.1 3.9 0.5 4.1 2.5 3.1 2.5 3.6 0.8 2.5 22.1 0.7 2.4 32.1 2.8 1.6 1.2 6.7 3.0 2.9 1.9 BLK MGC10442 ENSSSCG00000027568 "one2one with ENSG00000136573" "BLK proto-oncogene, Src family tyrosine kinase" P51451 14 14688908-14745981 "Human disease related genes" "Tissue enhanced" "Detected in many" "lymphoid tissue: 32.5;stomach: 14.4;upper respiratory system: 14.3" "Low region specificity" "Detected in many" "Cluster 78 - Lymphoid T cells" "Variable (upper respiratory system)" 1.2 1.7 2.4 1.6 2.3 1.2 16.9 0.7 1.8 6.4 3.9 1.3 2.6 2.5 8.8 2.6 2.6 1.5 1.7 1.6 8.0 4.4 0.8 2.5 1.9 1.0 6.7 1.0 2.4 4.7 2.2 2.1 0.7 1.9 5.7 1.9 6.5 0.1 1.4 2.2 4.9 0.2 4.5 1.4 16.1 43.0 1.4 1.6 1.2 7.3 1.7 4.0 22.7 2.2 1.3 1.2 2.2 0.2 2.6 3.0 0.6 1.0 2.0 1.7 1.2 8.8 5.4 2.1 0.5 1.2 1.8 0.8 1.1 2.7 1.6 1.5 20.9 2.8 10.9 0.6 1.9 1.6 1.1 0.8 2.2 4.3 1.3 52.2 3.0 1.9 50.6 4.8 1.5 1.3 1.8 1.8 1.7 1.8 BSND "BART, DFNB73" ENSSSCG00000020989 "one2one with ENSG00000162399" "Barttin CLCNK type accessory beta subunit" Q8WZ55 6 157425903-157432317 "Human disease related genes" "Tissue enriched" "Detected in some" 7 "kidney: 43.8" "Not detected" "Not detected" "Cluster 39 - Kidney transport" "Not variable" 0.0 0.0 0.0 0.0 0.0 0.0 0.9 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.4 70.1 3.6 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 4.5 0.0 0.0 3.3 1.8 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 3.3 0.3 0.0 0.0 0.0 0.0 0.0 BTK "AGMX1, ATK, IMD1, PSCTK1, XLA" ENSSSCG00000026742 "one2one with ENSG00000010671" "Tyrosine-protein kinase BTK " Q06187 X 82981207-83014583 "Human disease related genes" "Tissue enhanced" "Detected in many" "lymphoid tissue: 33.5;upper respiratory system: 17.9" "Low region specificity" "Detected in many" "Cluster 79 - Lymphoid myeloid" "Variable (brain, lymphoid tissue, upper respiratory system)" 6.2 0.3 3.5 1.9 6.0 0.3 15.2 1.1 2.8 9.8 0.7 0.3 1.4 1.8 12.6 0.9 7.0 3.3 7.7 1.3 11.3 10.0 1.1 0.9 2.1 0.5 8.3 1.7 1.2 8.1 0.9 0.8 0.5 8.9 5.8 1.9 11.9 0.0 0.6 2.4 4.4 0.0 1.5 1.1 21.6 37.4 6.0 5.0 1.9 7.5 1.5 3.3 26.8 1.8 5.9 0.6 8.5 0.6 5.0 1.1 1.2 5.5 1.6 1.3 3.1 10.7 0.2 2.1 0.5 0.4 6.6 0.3 0.4 0.9 2.0 1.6 19.6 3.0 5.7 1.5 3.3 7.2 3.7 6.8 2.1 0.3 4.2 4.0 0.8 1.2 51.2 4.7 0.8 1.0 2.3 3.3 3.6 7.2 C1QTNF6 "CTRP6, ZACRP6" ENSSSCG00000030325 "one2one with ENSG00000133466" "Complement C1q tumor necrosis factor-related protein 6 precursor " Q9BXI9 5 10601790-10608783 "Human disease related genes" "Tissue enhanced" "Detected in all" "dura mater: 39.8;lens: 77.4" "Low region specificity" "Detected in all" "Cluster 74 - Extracellular matrix" "Not variable" 10.7 3.8 4.3 4.8 46.6 7.9 5.8 2.8 3.6 6.1 7.7 9.5 10.4 4.1 6.4 9.7 6.1 3.5 8.8 11.4 5.1 137.6 27.1 14.0 4.2 2.8 7.1 21.8 7.1 11.6 3.9 5.2 4.2 4.7 3.2 4.0 5.2 2.3 5.3 9.5 4.7 51.2 17.1 1.9 7.9 9.7 6.7 7.8 2.9 12.5 3.0 9.3 37.1 17.2 37.6 12.3 4.9 12.2 14.3 6.6 6.0 3.4 3.5 3.5 2.9 5.5 13.5 3.7 1.8 4.5 4.0 3.9 12.3 11.3 4.8 3.4 4.1 4.1 3.7 14.4 3.7 9.1 5.7 17.3 4.3 20.8 4.9 8.7 7.8 5.5 11.7 6.3 4.0 9.1 8.6 4.3 3.8 8.8 CACNA1D "CACH3, CACN4, CACNL1A2, Cav1.3, CCHL1A2" ENSSSCG00000011455 "one2one with ENSG00000157388" "Calcium voltage-gated channel subunit alpha1 D" Q01668 13 35568624-35907913 "Human disease related genes" "Tissue enhanced" "Detected in many" "adrenal gland: 52.2;male glands: 30.6" "Low region specificity" "Detected in all" "Cluster 1 - Brain neurotransmission" "Variable (brain, lymphoid tissue, male glands)" 0.8 70.9 13.1 0.3 1.3 1.9 9.3 0.4 9.3 0.6 20.4 2.4 2.3 13.5 1.1 11.7 4.0 11.1 5.3 9.2 1.8 5.9 1.7 10.3 12.8 15.6 1.2 0.4 6.8 9.9 1.6 1.4 0.2 10.3 1.0 13.6 1.3 0.0 1.5 3.5 1.0 0.9 4.9 1.4 8.6 1.0 4.1 6.3 10.1 2.8 11.2 34.0 3.0 2.9 6.5 4.4 7.0 0.1 37.1 25.4 2.0 5.3 10.7 2.9 6.4 0.8 24.9 12.2 1.0 32.6 9.6 0.2 1.8 3.6 4.8 12.6 14.9 1.4 0.7 0.2 12.4 4.2 7.2 1.6 13.5 2.9 7.7 11.9 1.6 2.0 0.6 2.1 0.8 7.6 9.5 11.5 8.9 3.1 CAPN10 ENSSSCG00000037779 "one2one with ENSG00000142330" "Calpain-10 " Q9HC96 15 139557202-139570181 "Human disease related genes" "Low tissue specificity" "Detected in all" "Low region specificity" "Detected in all" "Cluster 70 - Housekeeping" "Not variable" 3.7 2.1 4.5 1.2 3.0 4.0 7.4 2.9 3.4 3.8 4.4 4.7 3.9 4.4 4.0 4.8 2.6 3.7 3.2 3.6 3.9 5.9 4.4 3.6 4.5 2.7 3.9 2.6 4.0 5.4 1.4 1.1 0.8 4.1 3.8 4.7 3.7 1.7 6.3 4.5 4.0 3.1 4.1 2.4 6.4 9.0 3.2 3.5 4.4 3.7 3.8 3.6 5.4 3.1 3.6 4.1 3.8 1.7 3.2 2.9 2.9 3.4 4.5 2.8 2.4 3.9 3.8 4.2 1.8 1.2 4.0 1.1 3.3 2.6 2.9 4.6 6.0 3.2 5.6 2.1 4.3 3.5 4.2 3.2 4.7 7.4 3.6 18.2 6.2 1.9 8.3 5.0 2.0 4.2 3.4 4.5 3.3 2.9 CARTPT CART ENSSSCG00000016972 "one2one with ENSG00000164326" "Cocaine- and amphetamine-regulated transcript protein precursor " Q16568 16 48043080-48045689 "Human disease related genes" "Group enriched" "Detected in some" 5 "brain: 68.0;retina: 21.4" "Region enhanced" "Detected in many" "hippocampal formation: 68.1" "Cluster 1 - Brain neurotransmission" "Variable (brain)" 0.0 4.5 48.7 0.0 0.0 0.0 0.0 0.0 3.7 0.4 0.1 0.0 0.1 12.7 0.9 0.0 1.5 40.3 4.3 0.0 1.3 0.0 0.0 0.0 16.1 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 42.2 1.3 11.3 3.5 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 8.2 21.5 14.4 0.0 11.4 22.5 0.0 0.6 0.0 0.0 28.0 0.0 0.6 30.3 0.1 8.2 13.2 0.0 4.4 0.8 85.2 9.0 0.0 0.0 38.3 0.0 0.0 0.0 6.3 20.9 0.0 0.0 0.0 0.0 40.0 3.9 3.3 0.0 43.2 0.0 3.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 179.9 12.7 0.3 CASR "FHH, GPRC2A, HHC, HHC1, NSHPT" ENSSSCG00000011878 "one2one with ENSG00000036828" "Extracellular calcium-sensing receptor " P41180 13 138280364-138364953 "Human disease related genes" "Tissue enhanced" "Detected in all" "kidney: 24.5;pituitary gland: 23.8" "Low region specificity" "Detected in all" "Cluster 39 - Kidney transport" "Not variable" 1.7 2.6 2.4 0.6 1.1 2.2 3.3 0.8 1.9 2.3 4.3 3.1 3.4 2.2 3.2 3.7 2.5 1.7 1.8 2.5 3.4 3.0 1.8 3.0 1.8 2.9 4.1 1.4 4.4 2.4 1.3 0.9 0.9 2.4 2.0 2.0 2.9 0.3 8.5 28.9 2.8 0.2 3.0 2.0 3.7 5.8 1.6 1.4 1.4 2.1 1.4 4.4 4.4 2.3 12.5 1.7 2.1 0.6 2.8 35.1 1.3 1.3 1.6 2.3 1.4 2.4 6.5 1.9 1.2 2.8 2.1 1.3 1.8 1.5 2.0 1.6 2.9 1.9 1.0 1.1 2.0 1.5 1.4 1.2 1.9 2.2 1.4 5.6 14.8 2.2 8.3 3.0 1.9 2.2 3.9 1.9 1.7 1.2 CD226 "DNAM-1, DNAM1, PTA1, TLiSA1" ENSSSCG00000038398 "one2one with ENSG00000150637" "CD226 molecule" Q15762 1 152882736-152979845 "Human disease related genes" "Tissue enhanced" "Detected in many" "lymphoid tissue: 24.6;stomach: 16.0;testis: 16.3" "Low region specificity" "Detected in many" "Cluster 78 - Lymphoid T cells" "Not variable" 3.5 0.8 1.3 0.9 9.2 1.1 10.1 0.5 1.0 12.9 1.2 1.1 1.8 1.4 12.2 1.5 1.0 1.1 1.5 1.0 7.1 7.0 0.6 1.5 1.2 0.9 2.3 1.0 1.5 2.5 0.5 0.4 0.4 1.2 7.2 1.4 6.1 0.0 2.0 7.6 3.0 0.2 1.4 1.5 10.0 24.7 0.9 0.9 1.0 2.5 1.0 2.0 2.5 2.0 1.0 0.6 1.2 0.3 2.0 1.3 1.1 0.7 1.1 0.8 0.7 10.6 4.1 1.4 0.9 0.9 1.0 0.5 0.5 0.9 1.3 1.0 12.4 5.2 9.3 0.9 1.5 1.2 0.9 0.7 1.2 22.9 0.8 12.7 1.6 1.0 14.9 4.5 0.7 1.4 1.4 1.0 1.0 1.0 CDC73 "C1orf28, FIHP, HRPT1, HRPT2, parafibromin" ENSSSCG00000010801 "one2one with ENSG00000134371" "Cell division cycle 73" Q6P1J9 10 575075-667480 "Human disease related genes" "Low tissue specificity" "Detected in all" "Low region specificity" "Detected in all" "Cluster 66 - Housekeeping mRNA" "Not variable" 16.2 18.4 18.0 6.2 10.9 13.7 21.8 36.4 17.7 23.2 26.3 24.0 24.5 17.3 21.5 33.6 25.9 21.0 22.1 19.4 17.9 25.0 10.0 26.5 16.3 13.4 23.9 9.9 25.4 17.1 6.3 5.0 5.9 23.1 10.2 15.4 13.8 2.4 10.4 21.0 17.6 7.7 21.0 5.4 28.4 18.0 20.1 20.4 15.2 16.3 15.9 26.0 18.4 17.6 20.6 13.1 23.5 4.7 37.2 45.6 7.5 18.9 15.4 11.9 16.3 20.8 43.8 16.5 11.3 17.5 23.1 6.4 16.8 12.1 19.5 18.4 12.1 8.9 8.4 7.6 19.4 22.7 22.1 9.8 16.2 25.7 19.5 34.9 48.8 19.3 21.8 22.5 10.4 15.2 28.5 20.0 19.8 18.3 CDKAL1 FLJ20342 ENSSSCG00000001080 "one2one with ENSG00000145996" "CDK5 regulatory subunit associated protein 1 like 1" Q5VV42 7 15910494-16674989 "Human disease related genes" "Low tissue specificity" "Detected in all" "Low region specificity" "Detected in all" "Cluster 66 - Housekeeping mRNA" "Not variable" 16.9 12.8 12.8 5.4 11.5 12.6 23.8 18.5 12.2 18.4 29.1 20.7 21.1 14.5 20.7 18.6 20.4 14.7 17.0 16.6 26.4 23.0 10.8 17.9 13.7 13.4 35.1 9.3 21.3 15.6 8.8 8.0 7.3 14.4 13.4 12.4 15.7 2.6 13.3 17.0 24.2 7.5 19.4 10.8 21.7 27.9 14.2 14.6 12.0 15.6 13.0 22.0 18.6 18.1 13.0 13.8 15.4 6.7 22.3 20.8 9.0 13.7 10.9 12.9 11.3 21.8 31.5 13.3 13.4 8.9 15.0 12.5 15.3 12.3 20.9 14.0 22.0 16.4 9.7 7.4 13.2 15.5 17.7 11.3 13.8 27.1 14.9 49.8 17.7 20.2 34.8 21.3 10.4 17.3 27.1 13.6 12.6 13.2 CDKN1B "KIP1, P27KIP1" ENSSSCG00000037144 "one2one with ENSG00000111276" "Cyclin-dependent kinase inhibitor 1B " P46527 5 59731208-59736685 "Human disease related genes" "Low tissue specificity" "Detected in all" "Low region specificity" "Detected in all" "Cluster 19 - Housekeeping mitochondrial" "Not variable" 66.3 27.9 50.2 23.5 35.7 39.6 49.5 42.6 39.5 38.6 151.7 129.4 39.1 62.5 42.0 58.8 88.8 64.9 100.7 55.1 39.6 104.9 23.1 91.2 62.3 16.9 38.9 39.2 88.8 54.6 20.1 17.4 16.9 72.6 21.2 55.1 33.7 14.5 24.0 57.5 38.8 22.1 40.8 14.0 70.4 51.8 64.2 70.9 56.6 39.8 64.3 108.4 41.9 37.0 33.6 51.7 70.8 24.1 109.3 105.1 41.4 63.2 54.1 18.4 37.9 40.6 107.7 61.2 13.3 37.9 60.8 36.8 25.1 19.2 64.8 73.8 32.1 16.4 12.7 26.7 62.9 75.6 84.9 43.3 59.0 17.6 70.5 85.0 55.0 25.2 41.1 61.5 20.6 53.9 248.5 59.1 48.1 68.9 CDKN2B "CDK4I, INK4B, MTS2, P15, p15INK4b, TP15" ENSSSCG00000034120 "one2one with ENSG00000147883" "Cyclin-dependent kinase 4 inhibitor B " P42772 1 200761004-200770633 "Human disease related genes" "Tissue enhanced" "Detected in all" "mouth: 21.6;small intestine: 20.9" "Low region specificity" "Detected in many" "Cluster 67 - Gastrointestinal" "Variable (mouth)" 1.6 2.7 1.5 0.7 1.8 1.4 12.5 1.9 1.2 23.5 2.8 2.0 2.6 1.3 17.8 12.0 1.5 1.5 2.0 1.4 15.4 2.1 1.2 2.4 1.1 1.0 9.7 1.1 2.0 2.6 0.9 0.9 0.7 1.7 15.3 1.2 10.7 0.3 1.7 2.7 7.8 1.4 7.3 1.1 16.2 4.2 1.4 1.2 0.9 3.4 0.9 2.7 3.7 27.3 4.8 1.3 1.6 0.6 2.1 4.8 1.0 1.0 1.1 5.8 1.1 10.6 4.2 1.1 1.3 2.3 1.5 0.7 11.6 5.2 1.7 0.8 3.2 12.5 10.4 0.9 1.1 1.8 1.1 1.8 1.2 7.9 1.3 4.8 4.4 17.8 8.5 4.8 2.2 6.6 3.0 2.6 1.1 1.6 CEL "BSSL, MODY8" ENSSSCG00000028671 "one2one with ENSG00000170835" "Carboxyl ester lipase" 1 272763226-272770353 "Human disease related genes" "Tissue enhanced" "Detected in many" "male glands: 9.0" "Low region specificity" "Detected in single" "Cluster 71 - Housekeeping regulation" "Not variable" 0.6 0.0 0.3 0.1 0.1 1.1 0.4 1.0 0.7 0.1 0.6 0.7 0.2 0.3 0.2 0.5 0.3 0.3 0.2 1.2 0.1 0.9 0.3 1.3 0.3 0.3 0.8 0.3 0.5 0.4 0.8 0.3 0.3 0.4 0.1 0.2 0.1 0.2 0.6 0.7 0.7 0.1 0.8 0.0 0.4 0.2 0.2 0.3 0.3 0.4 0.1 0.6 0.4 0.2 0.2 0.4 0.3 0.2 0.4 2.6 0.3 0.4 0.2 2.1 0.6 0.1 0.6 0.4 0.0 0.0 0.5 0.1 0.1 0.5 0.8 0.5 0.4 0.1 0.0 0.0 0.4 0.4 0.3 0.3 0.3 0.7 0.4 0.6 1.3 0.2 0.2 1.1 1.6 0.4 0.1 0.4 0.5 0.2 CELA2A "ELA2A, ELA2B, RP11-265F14.2" ENSSSCG00000003459 "one2many with ENSG00000142615,ENSG00000215704" "Chymotrypsin-like elastase family member 2A " "P08217, P08218" 6 74691653-74707598 "Human disease related genes" "Tissue enriched" "Detected in some" 11 "testis: 29.8" "Not detected" "Not detected" "Cluster 9 - Testis spermatogenesis" "Not variable" 0.4 0.0 0.2 0.1 0.2 0.0 0.0 0.0 0.1 0.2 0.0 0.3 1.0 0.3 0.2 0.0 0.5 0.3 0.3 0.2 0.1 0.1 0.0 0.2 0.2 0.0 0.0 0.1 0.8 0.3 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.3 0.3 0.1 0.0 0.2 0.1 0.0 0.1 0.1 0.0 0.2 0.0 3.2 0.1 0.0 0.2 0.1 0.0 0.3 0.2 0.1 0.2 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.2 0.1 0.1 0.1 0.1 0.2 0.4 0.5 0.1 0.2 29.4 0.3 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.2 0.1 0.4 CEP19 "C3orf34, MGC14126" ENSSSCG00000021918 "one2one with ENSG00000174007" "Centrosomal protein 19" Q96LK0 13 133420017-133427544 "Human disease related genes" "Low tissue specificity" "Detected in all" "Low region specificity" "Detected in all" "Cluster 2 - Brain neurotransmission" "Not variable" 4.3 4.1 8.5 1.6 3.3 4.3 4.6 6.6 7.3 5.0 15.1 6.8 8.4 10.4 5.8 18.3 6.6 10.3 6.0 6.1 5.7 8.6 3.7 7.9 9.3 3.5 7.6 3.6 7.0 4.1 2.7 2.2 2.4 8.6 2.4 9.0 3.2 0.8 3.1 6.3 4.7 2.1 6.2 2.7 4.6 4.8 6.3 7.5 8.6 3.4 9.5 13.4 4.5 7.1 3.9 3.9 8.3 1.8 11.6 12.0 2.7 7.3 9.1 4.7 5.4 4.7 17.7 9.3 3.0 4.0 8.9 4.2 4.9 2.7 5.1 10.8 3.9 2.8 2.0 2.8 9.7 7.6 7.9 3.6 9.5 4.8 7.1 12.9 8.4 5.7 6.0 4.9 3.9 4.8 6.9 10.3 7.3 5.8 CHD7 "CRG, FLJ20357, FLJ20361, KIAA1416" ENSSSCG00000006231 "one2one with ENSG00000171316" "Chromodomain helicase DNA binding protein 7" Q9P2D1 4 72573566-72694141 "Human disease related genes" "Low tissue specificity" "Detected in all" "Region enriched" "Detected in all" 4 "cerebellum: 36.8" "Cluster 66 - Housekeeping mRNA" "Variable (brain, lymphoid tissue)" 15.4 15.1 12.4 9.6 18.7 23.0 34.7 14.7 9.9 30.6 110.3 5.8 9.1 7.4 29.9 17.6 37.4 12.8 15.0 17.9 25.1 18.2 15.0 18.7 6.3 11.6 30.4 14.1 27.6 19.1 17.9 11.8 11.0 17.8 28.1 8.4 22.1 1.3 12.9 18.3 26.5 3.4 23.3 11.8 31.8 43.7 16.8 15.4 6.5 15.4 5.7 16.9 23.9 31.4 14.5 14.8 19.5 3.7 30.7 22.1 16.4 13.4 6.6 28.5 10.6 26.5 114.9 8.6 16.4 18.9 14.6 11.9 16.2 25.2 9.2 6.2 21.8 14.9 42.4 13.7 9.9 19.9 14.0 14.7 6.9 9.4 13.7 12.4 12.1 27.1 46.1 27.1 19.8 18.5 43.3 11.7 13.9 13.3 CISD2 "ERIS, Miner1, NAF-1, WFS2, ZCD2" ENSSSCG00000009164 "one2one with ENSG00000145354" "CDGSH iron sulfur domain 2" Q8N5K1 8 118152701-118164654 "Human disease related genes" "Tissue enhanced" "Detected in all" "male glands: 44.6" "Low region specificity" "Detected in all" "Cluster 10 - Housekeeping transcription" "Variable (male glands)" 7.7 18.8 9.4 2.0 4.4 2.9 10.1 45.2 10.0 11.3 21.1 8.5 46.1 12.4 10.8 14.8 17.3 12.4 14.7 9.3 8.2 18.3 3.4 11.7 10.1 7.8 8.7 3.0 9.7 8.4 3.5 3.0 4.2 16.0 4.3 9.3 6.5 2.0 5.6 13.9 8.4 5.9 7.7 7.1 14.5 8.5 15.2 14.8 11.2 7.5 11.3 13.8 10.6 8.6 22.8 4.8 14.6 2.4 39.6 24.2 3.1 15.3 10.1 7.1 10.1 10.5 25.7 12.5 5.0 9.2 16.0 4.6 5.6 1.7 7.1 12.9 6.8 5.1 2.7 3.0 10.6 16.9 15.7 5.6 10.0 22.0 14.3 11.8 12.0 8.2 9.4 10.9 5.3 4.6 5.5 10.4 12.2 14.8 CLEC16A "Gop-1, KIAA0350" ENSSSCG00000026569 "one2one with ENSG00000038532" "C-type lectin domain containing 16A" Q2KHT3 3 31938135-32158327 "Human disease related genes" "Low tissue specificity" "Detected in all" "Low region specificity" "Detected in all" "Cluster 66 - Housekeeping mRNA" "Not variable" 12.3 12.4 15.3 4.3 8.1 11.8 20.5 9.3 22.1 18.7 20.5 15.0 15.3 16.3 17.1 16.0 14.2 15.5 11.5 27.1 15.1 13.7 10.0 20.8 16.0 17.2 18.2 10.0 12.3 14.5 10.9 7.8 8.0 13.4 13.7 15.7 12.6 3.3 14.0 17.9 12.5 4.3 13.9 7.7 18.7 22.9 12.4 13.6 14.6 8.5 15.7 22.3 16.1 15.6 14.3 15.0 13.1 6.0 14.0 16.3 9.5 12.5 14.3 22.1 16.3 16.6 46.8 15.3 11.2 13.3 15.7 6.3 15.1 14.6 12.0 17.5 12.8 12.2 21.2 7.4 16.0 12.7 14.9 11.5 16.1 40.0 13.4 35.5 15.7 12.5 25.0 13.0 12.8 14.7 18.5 17.0 17.9 10.7 CTLA4 "CD, CD152, CELIAC3, GSE, IDDM12" ENSSSCG00000016122 "one2one with ENSG00000163599" "Cytotoxic T-lymphocyte protein 4 precursor " P16410 15 107282927-107289103 "Human disease related genes" "Tissue enhanced" "Detected in some" "large intestine: 8.5;lymphoid tissue: 20.8;stomach: 6.7" "Not detected" "Not detected" "Cluster 82 - Lymphoid B cell" "Variable (lymphoid tissue)" 0.3 0.0 0.2 0.6 0.3 0.1 3.9 0.5 0.0 5.8 0.0 0.0 0.1 0.0 7.9 0.0 0.1 0.1 0.3 0.0 2.2 0.6 0.0 0.0 0.1 0.0 1.5 0.0 0.0 0.8 0.0 0.1 0.0 0.3 1.5 0.1 2.0 0.0 0.0 0.6 0.8 0.0 0.2 0.0 4.9 14.1 0.2 0.2 0.0 2.4 0.0 0.1 4.8 0.4 0.1 0.1 0.6 0.0 0.4 0.3 0.2 0.2 0.0 0.1 0.0 4.2 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.1 2.6 0.0 0.7 0.6 2.9 0.3 0.0 0.3 0.1 0.2 0.0 0.1 0.1 5.0 2.3 0.4 18.9 0.9 1.0 0.1 0.4 0.0 0.0 0.2 CTSH "ACC-4, ACC-5, ACC4, ACC5, CPSB" ENSSSCG00000001770 "one2one with ENSG00000103811" "Pro-cathepsin H Cathepsin H mini chain Cathepsin H Cathepsin H heavy chain Cathepsin H light chain" P09668 7 48083572-48106074 "Human disease related genes" "Tissue enhanced" "Detected in all" "ovary: 77.2;synovial tissue: 85.6" "Low region specificity" "Detected in many" "Cluster 71 - Housekeeping regulation" "Variable (brain, lymphoid tissue)" 58.6 24.2 2.8 28.5 32.3 38.9 62.6 21.1 2.3 48.7 4.9 61.7 67.5 2.8 46.6 75.7 3.2 2.5 17.1 16.4 30.8 60.0 34.5 36.7 2.7 4.5 30.3 17.1 14.6 51.6 9.7 7.7 4.5 3.9 9.9 2.7 23.9 10.1 31.9 45.2 16.8 9.3 45.3 13.4 109.6 70.2 5.4 3.3 2.0 29.0 2.0 8.7 60.3 35.9 257.3 54.4 4.2 31.7 24.2 21.7 35.8 3.2 2.2 10.1 1.6 38.7 8.4 2.6 4.4 27.9 3.5 6.1 27.5 24.9 27.7 2.4 28.0 17.5 17.1 24.8 3.2 5.8 8.3 216.5 3.1 17.9 3.8 26.9 39.8 21.9 82.7 35.3 10.4 24.3 29.8 2.8 2.5 8.0 CYP11A1 "CYP11A, P450SCC" ENSSSCG00000025273 "one2one with ENSG00000140459" "Cholesterol side-chain cleavage enzyme, mitochondrial " P05108 7 59175820-59188720 "Human disease related genes" "Group enriched" "Detected in some" 117 "adrenal gland: 230.0;ovary: 287.1;testis: 79.2" "Not detected" "Not detected" "Cluster 20 - Hormonal" "Variable (brain, lymphoid tissue)" 0.0 1843.8 0.4 0.2 0.0 0.9 7.4 0.2 2.2 0.3 0.0 0.3 0.0 0.1 0.3 0.4 0.4 1.3 0.0 0.0 0.3 0.3 0.0 2.7 0.1 0.0 0.1 0.1 11.7 0.3 0.0 0.0 0.0 2.2 0.1 0.0 0.1 0.0 0.0 1.0 2.8 0.0 0.3 0.0 7.4 0.6 0.5 0.2 0.1 0.7 0.1 0.2 2.4 0.2 2878.2 0.9 6.9 0.0 0.3 1.5 0.3 1.5 0.1 0.0 0.0 0.3 0.1 0.0 7.6 0.4 1.3 0.0 0.0 0.1 0.1 0.1 0.6 0.0 0.0 0.0 0.6 0.2 0.1 0.7 0.0 979.2 0.4 0.8 0.0 0.4 5.2 8.0 0.1 0.0 0.4 1.5 0.3 0.0 CYP17A1 "CPT7, CYP17, P450C17, S17AH" ENSSSCG00000010591 "one2one with ENSG00000148795" "Steroid 17-alpha-hydroxylase/17,20 lyase " P05093 14 113805753-113812504 "Human disease related genes" "Group enriched" "Detected in some" 227 "adrenal gland: 453.1;testis: 241.1" "Not detected" "Not detected" "Cluster 20 - Hormonal" "Not variable" 0.0 4973.8 0.2 0.1 0.0 0.0 0.0 0.8 0.1 0.8 0.2 0.0 1.4 0.1 0.9 0.0 0.0 0.2 0.1 0.1 0.6 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.6 0.2 0.2 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.1 2.3 0.0 0.1 0.0 0.1 0.0 0.2 0.1 0.1 0.0 0.1 0.2 0.0 0.0 20.9 0.1 0.2 0.0 0.1 0.2 0.1 0.1 0.1 0.0 0.0 1.4 0.1 0.2 0.1 1.5 0.1 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.2 0.4 0.2 4082.1 0.2 0.1 0.0 0.1 0.1 0.0 0.6 0.0 0.7 0.2 0.1 0.1 CYP19A1 "ARO, ARO1, aromatase, CPV1, CYAR, CYP19, P-450AROM" ENSSSCG00000030168 "one2one with ENSG00000137869" "Aromatase 1 " P11511 1 120477197-120696877 "Human disease related genes" "Tissue enriched" "Detected in all" 49 "testis: 249.1" "Low region specificity" "Detected in all" "Cluster 9 - Testis spermatogenesis" "Variable (male glands)" 7.7 10.2 24.9 2.5 6.1 9.1 14.6 3.5 17.0 11.5 31.3 14.1 20.4 21.5 12.6 21.2 18.5 13.5 9.5 16.6 11.5 17.0 6.4 14.9 18.9 11.6 15.5 5.7 18.5 8.7 6.6 4.1 4.7 22.6 5.7 21.9 5.6 0.8 7.1 14.7 12.1 1.9 13.2 6.6 19.4 9.5 9.2 10.5 13.6 8.2 14.8 33.5 11.2 10.6 14.0 8.4 15.6 2.8 24.6 16.9 4.8 8.8 16.6 8.6 10.3 10.1 61.5 20.9 4.3 12.0 26.8 8.8 7.9 6.6 11.1 13.4 8.8 4.3 1.9 4.8 21.2 15.6 8.4 7.4 20.2 2040.7 14.7 32.2 24.4 10.5 13.7 13.3 8.1 8.8 21.3 19.0 18.0 8.0 CYP21A2 "CA21H, CAH1, CPS1, CYP21, CYP21B, P450c21B" ENSSSCG00000001428 "one2one with ENSG00000231852" "Steroid 21-hydroxylase " P08686 7 24086258-24089371 "Human disease related genes" "Tissue enriched" "Detected in many" 50 "adrenal gland: 367.3" "Not detected" "Not detected" "Cluster 76 - Housekeeping regulation" "Variable (kidney, upper respiratory system)" 16.0 2893.8 0.3 4.1 0.4 6.2 2.7 2.3 0.2 3.6 0.8 20.5 2.1 0.4 4.1 1.4 0.2 0.3 2.0 6.9 4.6 2.1 9.4 11.9 0.5 1.4 8.5 12.1 6.5 15.7 8.9 9.4 3.7 0.5 2.6 0.3 6.1 11.9 0.4 7.2 3.1 0.0 21.3 0.4 4.0 1.0 1.1 1.1 0.4 0.7 0.6 1.2 0.7 15.4 2.3 29.0 0.6 10.0 1.0 0.9 17.7 0.7 0.4 2.0 0.8 7.6 0.3 0.3 0.5 4.2 0.4 4.8 3.9 3.9 21.1 0.8 1.3 4.9 2.1 7.4 0.6 1.4 2.4 42.4 0.4 3.1 1.1 0.5 1.7 16.3 2.1 8.6 4.8 16.0 22.3 0.4 0.4 1.5 CYP27B1 "CYP1, P450c1, PDDR, VDD1" ENSSSCG00000028637 "one2one with ENSG00000111012" "25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial " O15528 5 23050114-23058435 "Human disease related genes" "Low tissue specificity" "Detected in all" "Low region specificity" "Detected in all" "Cluster 44 - Housekeeping" "Not variable" 4.6 7.1 8.3 1.7 3.1 5.0 9.9 3.3 6.7 6.1 9.8 7.4 8.1 7.2 6.7 10.0 8.3 6.3 5.4 7.8 6.8 6.8 4.8 9.4 6.3 3.8 9.2 3.4 10.6 5.7 3.6 2.5 2.3 10.4 3.1 6.9 3.5 0.7 11.3 7.5 7.2 0.7 9.2 3.1 10.6 5.8 5.8 6.5 5.4 4.9 5.1 9.3 6.1 6.4 5.4 4.5 8.9 1.5 6.9 6.3 3.2 7.0 5.7 5.7 6.8 5.6 15.0 6.7 3.2 5.1 7.8 4.7 5.7 3.7 6.0 5.0 5.4 2.9 1.6 2.7 6.5 7.2 6.4 3.7 6.7 6.9 5.4 24.3 10.3 6.6 9.1 7.4 5.9 5.9 10.3 7.8 6.5 4.4 DICER1 "Dicer, HERNA, K12H4.8-LIKE, KIAA0928, MNG1" ENSSSCG00000028225 "one2one with ENSG00000100697" "Endoribonuclease Dicer " Q9UPY3 7 116361678-116436396 "Human disease related genes" "Low tissue specificity" "Detected in all" "Low region specificity" "Detected in all" "Cluster 66 - Housekeeping mRNA" "Not variable" 38.6 40.5 27.6 11.4 26.3 28.7 38.8 18.4 24.1 35.4 47.2 40.7 39.7 26.1 33.6 52.7 50.9 29.5 32.5 36.8 34.2 42.2 18.7 44.2 24.3 30.7 38.0 29.0 52.6 32.6 17.7 15.1 15.3 32.7 23.0 25.2 26.5 6.2 31.6 45.4 30.7 12.6 38.5 16.0 38.3 37.2 29.8 29.8 21.8 24.2 21.4 43.3 31.6 35.5 31.5 31.9 31.5 10.3 31.6 41.8 18.8 25.1 23.1 22.0 22.6 32.8 56.3 25.3 22.3 37.4 32.0 19.8 22.7 21.3 38.5 24.6 30.4 23.3 29.2 21.0 29.1 33.5 28.9 24.8 25.0 25.5 28.6 68.9 67.5 35.5 43.0 35.0 19.1 32.7 53.9 30.8 30.0 27.6 DUOX2 "LNOX2, P138-TOX, P138(TOX), THOX2" ENSSSCG00000004678 "one2one with ENSG00000140279" "Dual oxidase 2 precursor " Q9NRD8 1 126620510-126642480 "Human disease related genes" "Group enriched" "Detected in many" 5 "gallbladder: 21.4;large intestine: 37.0;stomach: 52.0;thyroid gland: 72.5;upper respiratory system: 24.4" "Not detected" "Not detected" "Cluster 67 - Gastrointestinal" "Variable (large intestine, lymphoid tissue, male glands)" 2.6 1.8 2.1 0.8 0.6 2.0 11.6 0.4 0.9 108.2 2.6 3.3 1.6 1.1 52.3 3.6 1.2 1.2 0.7 2.1 3.3 1.9 1.5 2.9 0.9 1.3 3.1 1.4 2.0 63.6 0.5 0.4 0.4 1.0 2.1 1.1 2.8 0.0 1.4 2.2 57.7 0.1 4.3 1.1 10.7 1.3 0.6 0.6 0.7 22.0 0.7 2.0 19.6 5.3 16.3 1.2 1.1 1.8 32.0 1.3 3.5 0.5 0.8 1.2 0.6 11.7 7.4 1.1 2.1 3.2 1.0 0.6 1.7 2.3 5.1 0.9 3.2 4.4 73.1 0.8 1.3 0.8 1.4 0.9 1.0 3.9 0.6 3.4 251.3 4.1 6.9 79.6 1.1 3.9 3.0 1.7 0.9 0.6 DUOXA2 ENSSSCG00000004676 "one2one with ENSG00000140274" "Dual oxidase maturation factor 2 " Q1HG44 1 126603069-126652463 "Human disease related genes" "Tissue enhanced" "Detected in many" "large intestine: 30.1;stomach: 34.1;thyroid gland: 45.4;upper respiratory system: 28.0" "Low region specificity" "Detected in single" "Cluster 67 - Gastrointestinal" "Variable (large intestine, male glands)" 1.0 0.9 1.5 1.1 0.0 1.1 17.9 0.0 0.0 64.8 0.2 1.5 0.0 0.1 18.7 1.2 0.1 1.1 0.1 1.1 1.5 0.0 0.5 1.9 0.4 0.3 1.2 0.6 0.1 15.9 0.0 0.0 0.0 0.6 1.0 0.1 1.5 0.0 0.3 0.4 46.9 0.0 1.9 0.6 19.6 0.1 0.1 0.1 0.1 11.0 0.1 0.2 9.2 1.3 28.4 0.4 0.3 1.9 13.9 0.2 1.1 0.1 0.2 0.0 0.0 6.3 1.8 0.2 0.3 5.5 0.3 0.1 0.4 0.5 2.9 0.0 0.9 1.9 34.9 0.3 0.6 0.1 0.6 0.2 0.2 2.5 0.2 0.1 114.4 2.1 4.4 67.7 0.2 2.4 0.6 2.6 0.0 0.3 DUSP6 "MKP-3, PYST1" ENSSSCG00000037910 "one2one with ENSG00000139318" "Dual specificity protein phosphatase 6 " Q16828 5 93303519-93309678 "Human disease related genes" "Low tissue specificity" "Detected in many" "Low region specificity" "Detected in all" "Cluster 81 - Vasculature and connective tissue" "Variable (brain, cartilage)" 24.2 7.0 7.9 7.7 21.4 13.3 15.0 10.2 12.5 15.7 3.3 4.4 6.2 16.5 15.7 19.6 6.6 14.9 14.4 15.1 10.9 20.3 6.8 15.4 17.0 3.2 16.8 9.0 22.3 10.5 5.0 4.1 3.6 9.3 5.0 13.7 6.2 0.1 5.8 31.0 18.5 0.0 11.4 14.7 34.7 7.7 7.1 8.5 13.3 13.5 18.4 7.6 17.5 7.8 48.7 10.9 7.2 2.5 7.8 35.8 7.4 7.9 16.0 4.4 13.1 13.0 5.4 17.0 6.8 13.5 8.8 4.4 10.7 3.8 9.8 15.7 12.5 3.9 2.7 11.7 9.9 8.7 9.8 17.1 14.7 3.5 8.7 7.8 8.6 8.5 8.9 19.0 7.9 5.8 29.5 13.9 8.8 8.3 DYRK1B MIRK ENSSSCG00000027197 "one2one with ENSG00000105204" "Dual specificity tyrosine phosphorylation regulated kinase 1B" Q9Y463 6 48305847-48314517 "Human disease related genes" "Tissue enhanced" "Detected in all" "skeletal muscle: 71.1" "Low region specificity" "Detected in all" "Cluster 66 - Housekeeping mRNA" "Not variable" 36.4 30.2 22.3 9.6 18.0 27.8 48.1 18.9 21.1 25.1 28.8 39.6 36.5 21.1 24.1 24.6 22.9 22.2 20.3 38.9 25.8 26.8 17.5 43.4 21.3 25.9 36.1 27.5 47.9 30.9 17.5 14.5 11.9 26.0 24.7 21.9 24.5 4.6 29.9 36.3 27.5 7.0 53.3 11.8 48.2 41.8 18.9 20.6 18.1 17.3 17.8 35.7 27.1 56.3 16.1 38.8 25.0 13.5 26.4 37.9 16.7 20.1 19.3 23.1 16.0 23.4 49.5 20.7 14.0 23.5 22.1 78.0 17.7 19.8 31.5 21.7 25.5 20.6 31.3 20.3 23.4 22.4 23.7 46.1 22.5 158.3 21.0 84.7 42.6 34.2 36.3 42.8 35.8 30.3 52.5 24.0 20.0 17.4 EIF2AK3 "PEK, PERK" ENSSSCG00000008208 "one2one with ENSG00000172071" "Eukaryotic translation initiation factor 2 alpha kinase 3" Q9NZJ5 3 57423943-57506246 "Human disease related genes" "Tissue enhanced" "Detected in all" "male glands: 53.2" "Low region specificity" "Detected in all" "Cluster 69 - Housekeeping" "Not variable" 15.1 11.1 12.8 5.8 13.0 11.8 32.0 83.3 10.4 32.6 37.2 20.3 15.7 15.7 33.3 18.2 19.7 16.0 16.7 17.9 48.8 30.5 13.0 20.2 14.5 19.0 64.0 9.1 18.2 26.2 6.9 6.9 4.8 16.8 16.1 13.2 20.2 7.7 19.4 29.6 44.6 4.5 14.8 6.9 33.6 37.0 15.0 16.7 13.0 26.8 14.3 21.9 21.6 15.2 23.9 14.7 15.2 5.1 17.2 31.5 9.3 14.6 13.1 27.3 10.0 32.6 20.7 15.0 38.2 25.5 16.0 5.0 9.2 9.0 14.0 16.2 20.2 42.0 28.4 7.5 14.7 15.5 17.7 16.7 14.0 6.3 16.0 60.8 23.7 13.8 41.8 32.7 21.1 14.1 24.3 15.7 13.5 13.9 ENPP1 "M6S1, NPPS, PC-1, PCA1, PDNP1" ENSSSCG00000004193 "one2one with ENSG00000197594" "Ectonucleotide pyrophosphatase/phosphodiesterase 1" P22413 1 31722508-31797460 "Human disease related genes" "Tissue enriched" "Detected in many" 4 "cartilage: 130.3" "Low region specificity" "Detected in many" "Cluster 76 - Housekeeping regulation" "Variable (brain, cartilage, lymphoid tissue)" 53.9 6.2 1.4 12.5 17.4 10.4 36.5 63.5 1.7 4.2 2.7 11.7 18.0 1.1 7.8 151.5 4.7 2.4 22.6 40.9 14.2 135.3 22.7 37.3 3.6 33.9 18.2 18.3 21.4 12.8 20.5 17.4 19.6 3.1 5.1 0.7 9.2 80.8 15.7 50.8 11.4 0.6 20.2 19.9 42.4 11.4 7.1 5.2 1.0 6.8 0.7 5.9 6.8 12.6 42.8 18.6 3.5 35.0 16.1 10.4 22.3 4.9 0.7 19.1 4.8 13.7 2.3 1.0 12.6 53.2 2.0 10.4 8.7 5.5 25.3 0.9 7.2 6.9 3.2 9.2 4.4 9.4 39.5 66.0 1.6 4.7 4.9 109.0 4.3 26.4 11.8 18.5 17.1 8.9 51.4 2.8 1.7 11.9 EPO EP ENSSSCG00000007673 "one2one with ENSG00000130427" "Erythropoietin " P01588 3 8620508-8622936 "Human disease related genes" "Tissue enhanced" "Detected in some" "testis: 5.3" "Not detected" "Not detected" "Cluster 9 - Testis spermatogenesis" "Not variable" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 ESR1 "ER-alpha, Era, ESR, NR3A1" ENSSSCG00000025777 "one2one with ENSG00000091831" "Estrogen receptor " P03372 1 14217036-14507715 "Human disease related genes" "Group enriched" "Detected in many" 5 "cervix: 80.7;endometrium: 72.0;fallopian tube: 57.2" "Low region specificity" "Detected in many" "Cluster 71 - Housekeeping regulation" "Variable (brain)" 8.9 4.3 5.9 7.0 3.9 34.8 5.5 0.6 3.1 0.7 5.2 319.5 3.2 2.2 0.7 1.1 1.4 3.2 1.8 4.4 1.0 2.9 3.0 321.8 2.0 4.3 3.1 4.2 241.2 1.2 0.4 0.4 0.2 7.7 0.4 2.2 0.6 0.9 13.6 6.7 6.2 0.2 3.9 3.6 5.0 1.2 2.1 2.1 2.1 3.1 1.6 1.3 4.5 2.7 7.8 3.2 4.5 8.1 1.7 27.5 2.4 2.6 1.7 1.0 2.3 1.0 1.9 2.0 0.5 0.7 4.6 7.7 2.1 2.4 1.0 1.6 2.3 0.1 0.7 2.8 2.3 3.0 1.9 5.6 2.0 3.6 2.0 1.5 0.6 2.1 2.3 6.6 1.2 13.8 1.1 3.3 2.9 1.6 FEZF1 ZNF312B ENSSSCG00000031221 "one2one with ENSG00000128610" "FEZ family zinc finger 1" A0PJY2 18 24879031-24884917 "Human disease related genes" "Tissue enhanced" "Detected in some" "brain: 10.4;pituitary gland: 3.4;upper respiratory system: 15.2" "Region enriched" "Detected in some" 9 "hypothalamus: 10.4" "Cluster 23 - Cilium structure" "Variable (brain, upper respiratory system)" 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 5.7 0.0 0.1 1.5 0.0 0.0 0.0 0.0 0.0 0.1 2.6 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 FFAR4 "GPR120, GPR129, O3FAR1, PGR4" ENSSSCG00000010478 "one2one with ENSG00000186188" "Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha' " Q5NUL3 14 105011408-105033633 "Human disease related genes" "Tissue enhanced" "Detected in many" "adipose tissue: 16.2;upper respiratory system: 28.1" "Low region specificity" "Detected in many" "Cluster 23 - Cilium structure" 8.7 0.7 1.6 3.3 3.6 0.5 12.7 0.0 0.3 6.3 0.4 0.4 0.6 3.5 7.4 0.8 0.4 1.5 0.2 0.5 1.1 0.8 0.4 6.3 3.3 0.4 1.0 12.4 16.6 7.2 0.2 0.1 0.1 0.6 0.5 2.8 0.6 0.1 0.9 2.4 16.5 0.0 0.8 0.7 14.6 0.5 0.2 0.4 2.1 8.6 1.4 0.6 15.8 0.6 0.2 0.6 0.4 0.1 0.4 18.7 2.3 0.1 3.7 0.9 0.2 8.4 0.9 3.3 0.1 0.9 0.5 0.4 0.7 0.7 0.6 2.1 0.6 0.6 2.3 5.6 1.9 1.6 0.1 0.4 2.9 5.1 0.1 1.2 5.3 0.4 0.5 38.3 1.3 0.4 0.5 1.3 0.8 0.2 FGF17 FGF-13 ENSSSCG00000009609 "one2one with ENSG00000158815" "Fibroblast growth factor 17" O60258 14 6310169-6314976 "Human disease related genes" "Tissue enhanced" "Detected in many" "epididymis: 19.5" "Low region specificity" "Detected in some" "Cluster 66 - Housekeeping mRNA" "Not variable" 0.6 1.2 0.6 0.0 0.0 2.2 0.3 1.3 0.5 0.3 5.4 0.7 5.9 0.3 0.2 5.3 0.2 0.3 0.3 1.6 0.6 0.7 1.2 1.9 0.4 9.2 1.7 0.5 2.4 0.4 0.8 0.2 0.6 1.2 0.1 0.6 0.3 0.3 3.8 7.0 1.2 0.3 1.5 0.3 0.3 0.5 0.2 0.6 0.3 0.9 0.3 1.2 2.3 0.4 0.0 0.7 0.7 0.9 3.0 4.7 0.0 0.5 0.3 2.4 0.3 0.6 2.4 0.4 0.7 1.2 0.7 0.0 0.6 0.4 0.1 0.3 0.3 0.5 0.6 0.7 0.7 0.4 0.6 0.3 0.5 0.1 0.5 1.1 6.6 0.6 0.6 0.7 1.1 0.2 0.2 0.4 0.6 0.2 FGF8 AIGF ENSSSCG00000036146 "one2one with ENSG00000107831" "Fibroblast growth factor 8" P55075 14 112808107-112813870 "Human disease related genes" "Tissue enhanced" "Detected in some" "adipose tissue: 3.5;brain: 2.1;cartilage: 1.8;retina: 2.1" "Low region specificity" "Detected in many" "Cluster 1 - Brain neurotransmission" "Not variable" 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 FGFR1 "BFGFR, CD331, CEK, FLG, FLT2, H2, H3, H4, H5, KAL2, N-SAM" ENSSSCG00000015815 "one2one with ENSG00000077782" "Fibroblast growth factor receptor 1" P11362 15 48053367-48106860 "Human disease related genes" "Tissue enhanced" "Detected in all" "cartilage: 88.1" "Low region specificity" "Detected in all" "Cluster 74 - Extracellular matrix" "Variable (brain)" 99.3 29.1 29.5 23.5 46.2 68.5 29.4 9.3 22.1 14.5 246.0 66.1 79.8 17.9 20.7 66.2 25.3 42.1 59.2 29.8 17.5 117.1 82.8 38.8 20.0 11.1 76.0 65.8 48.8 72.8 47.2 36.2 24.0 42.0 9.8 18.8 16.9 46.5 13.7 36.6 32.4 6.9 56.9 5.6 33.9 12.1 42.1 34.8 15.4 30.4 13.5 28.4 31.6 31.1 38.6 86.3 50.6 30.4 48.3 62.6 52.8 48.0 15.9 8.2 13.2 22.4 22.5 17.6 39.7 10.7 30.3 14.6 27.4 19.1 84.9 15.9 14.0 12.3 9.7 40.0 32.1 42.3 50.0 77.2 20.1 11.8 31.3 14.5 44.7 26.4 18.5 57.0 11.0 59.3 99.7 38.4 21.0 44.8 FH fumarase ENSSSCG00000028178 "one2one with ENSG00000091483" "Fumarate hydratase, mitochondrial " P07954 10 12402675-12431821 "Human disease related genes" "Tissue enhanced" "Detected in all" "skeletal muscle: 54.3" "Low region specificity" "Detected in all" "Cluster 19 - Housekeeping mitochondrial" "Not variable" 17.7 16.6 19.3 5.7 9.8 12.7 12.0 22.4 18.7 27.6 40.6 25.8 32.0 26.1 24.9 19.8 22.0 27.3 25.8 11.1 19.4 19.1 7.6 25.9 24.6 6.0 14.6 10.1 17.1 16.9 11.7 7.6 20.2 26.9 8.6 20.8 13.3 1.8 17.2 20.8 13.2 13.2 18.4 19.5 14.4 13.0 26.5 27.5 22.6 11.4 24.9 31.1 15.9 20.0 31.1 9.4 25.9 3.9 32.2 28.5 7.5 26.2 23.1 8.6 16.5 21.4 35.1 23.9 6.5 6.5 25.3 42.5 10.5 5.4 22.7 30.0 7.8 8.0 5.5 8.7 23.6 27.5 31.9 12.3 26.6 22.5 28.7 22.0 18.1 15.6 17.2 18.8 14.2 11.7 15.1 24.7 21.7 26.1 FLRT3 ENSSSCG00000007079 "one2one with ENSG00000125848" "Fibronectin leucine rich transmembrane protein 3" Q9NZU0 17 22940499-22954452 "Human disease related genes" "Tissue enhanced" "Detected in many" "skin: 24.8" "Low region specificity" "Detected in all" "Cluster 1 - Brain neurotransmission" "Not variable" 3.4 0.8 10.4 1.3 1.0 2.3 5.0 2.4 15.7 5.3 27.8 2.0 9.2 19.9 7.6 8.6 8.1 20.2 10.7 9.8 28.8 4.6 2.9 1.8 18.4 0.4 3.7 1.3 4.2 3.3 2.4 1.8 0.9 15.3 6.6 13.9 10.6 0.2 1.5 3.1 2.1 6.9 12.0 1.4 7.9 0.6 10.0 16.1 15.3 2.0 16.7 12.3 3.7 4.1 3.6 3.0 12.7 2.2 24.3 11.6 1.5 16.3 16.4 0.9 11.0 7.4 17.3 15.9 1.3 1.0 18.0 0.3 24.4 4.1 3.1 20.5 2.5 6.2 1.5 1.5 21.8 16.6 14.4 2.5 16.7 3.4 14.5 1.7 12.0 7.0 1.2 2.7 0.7 2.4 32.7 19.7 17.8 6.8 FOXE1 "FKHL15, FOXE2, HFKH4, TITF2, TTF-2" ENSSSCG00000005369 "one2one with ENSG00000178919" "Forkhead box E1" O00358 1 239727855-239728976 "Human disease related genes" "Tissue enriched" "Detected in some" 27 "thyroid gland: 117.2" "Not detected" "Not detected" "Cluster 38 - Lung and thyroid development" "Variable (lymphoid tissue)" 0.2 0.1 0.0 0.1 0.0 0.0 1.3 2.9 0.2 0.2 0.0 0.7 0.1 0.0 0.1 1.8 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.4 0.0 0.0 9.4 0.0 0.1 1.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.1 10.4 0.0 9.7 0.0 1.2 0.4 0.0 0.0 0.0 6.5 0.0 0.0 12.9 8.3 0.0 0.4 0.0 0.5 0.1 1.0 0.1 0.0 0.0 0.2 0.4 0.1 0.3 0.1 3.0 0.0 0.1 0.0 7.6 0.3 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.6 467.1 5.3 8.6 16.4 1.2 0.4 0.1 0.0 0.1 0.0 FOXI1 "FKHL10, FREAC6" ENSSSCG00000017009 "one2one with ENSG00000168269" "Forkhead box I1" Q12951 16 53836400-53839109 "Human disease related genes" "Tissue enriched" "Detected in some" 6 "kidney: 61.2" "Not detected" "Not detected" "Cluster 65 - Epithelium" "Variable (kidney)" 0.1 0.0 0.0 0.0 0.1 2.1 4.8 2.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 2.4 5.7 0.1 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 73.2 29.6 10.8 0.0 0.2 0.1 2.1 0.4 0.0 0.1 0.0 14.0 0.0 0.0 11.3 7.0 0.0 0.8 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.9 0.0 0.1 0.0 0.0 7.8 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.7 0.2 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.6 0.0 0.0 0.7 13.6 0.8 0.0 0.0 0.0 0.0 0.0 FOXP3 "AIID, DIETER, IPEX, JM2, PIDX, SCURFIN, XPID" ENSSSCG00000012300 "one2one with ENSG00000049768" "Forkhead box protein P3 " Q9BZS1 X 43302539-43328735 "Human disease related genes" "Tissue enriched" "Detected in many" 5 "lymphoid tissue: 23.0" "Not detected" "Not detected" "Cluster 82 - Lymphoid B cell" "Variable (lymphoid tissue)" 0.4 0.6 0.5 0.3 0.3 0.2 1.0 0.1 0.5 2.6 0.5 0.1 1.0 0.4 3.3 0.6 0.7 0.5 0.5 0.5 1.1 0.2 0.3 0.4 0.4 0.7 0.5 0.3 0.6 0.6 0.0 0.1 0.0 0.7 0.8 0.4 0.9 0.0 0.2 0.7 0.3 0.4 0.2 0.3 1.0 13.4 0.5 0.4 0.3 0.5 0.4 0.5 0.9 0.4 1.0 0.1 0.6 0.0 0.6 1.0 0.1 0.5 0.4 0.3 0.4 1.5 1.6 0.4 0.1 0.4 0.6 0.1 0.1 0.3 0.2 0.4 0.7 0.3 1.3 0.4 0.4 0.5 0.4 0.1 0.4 2.1 0.5 7.1 0.2 0.3 4.1 0.5 0.0 0.1 1.0 0.6 0.5 0.4 FSHB ENSSSCG00000013328 "one2many with ENSG00000131808" "Follitropin subunit beta " P01225 2 30386995-30399287 "Human disease related genes" "Tissue enriched" "Detected in many" 65 "pituitary gland: 353.5" "Low region specificity" "Detected in all" "Cluster 44 - Housekeeping" "Variable (brain)" 12.3 10.8 26.3 3.4 9.5 11.3 14.8 3.3 19.5 13.9 64.8 20.4 34.5 28.7 16.1 24.1 18.5 18.8 11.4 17.3 14.2 23.3 9.5 21.7 25.5 10.1 21.3 10.6 26.2 12.5 7.4 5.9 6.0 60.4 7.0 27.8 8.2 0.5 6.7 17.4 14.2 2.3 21.4 6.5 19.3 12.3 10.8 12.6 18.2 9.4 21.7 53.4 12.3 15.5 11.3 11.9 19.7 4.8 35.1 5078.8 7.0 9.1 21.8 7.2 11.9 13.0 93.7 26.7 5.5 9.2 20.5 12.2 7.9 12.4 14.3 19.9 7.6 4.0 1.7 7.2 23.9 13.2 9.9 10.6 25.0 21.5 10.1 40.8 23.9 16.4 18.2 17.1 8.8 10.6 22.6 20.4 17.5 9.0 FTO "ALKBH9, KIAA1752, MGC5149" ENSSSCG00000035949 "one2one with ENSG00000140718" "Alpha-ketoglutarate-dependent dioxygenase FTO " Q9C0B1 6 31174569-31564906 "Human disease related genes" "Low tissue specificity" "Detected in all" "Low region specificity" "Detected in all" "Cluster 3 - Brain cellular structure" "Not variable" 21.7 19.3 57.4 7.8 16.7 23.4 22.5 17.5 60.7 14.4 81.7 40.8 39.7 59.6 15.9 44.4 73.4 59.7 69.2 25.8 16.9 53.8 13.6 34.3 55.8 14.3 23.0 16.1 25.3 24.5 10.2 8.8 9.3 90.1 9.6 54.3 13.2 5.0 21.2 32.1 17.0 11.4 17.3 8.6 20.8 19.6 68.9 75.5 52.2 11.7 52.0 74.2 17.9 18.4 28.9 26.3 80.0 7.6 56.3 60.1 11.5 71.6 55.2 18.6 56.5 16.3 60.4 57.0 7.7 6.3 70.9 9.5 12.1 9.5 31.1 63.0 14.8 9.6 12.1 10.9 66.4 79.1 68.5 17.6 56.9 12.6 74.5 31.1 57.7 15.1 18.0 21.0 11.4 22.0 38.1 68.5 61.1 62.7 GCK "HK4, MODY2" ENSSSCG00000016751 "one2one with ENSG00000106633" "Myosin regulatory light chain 2, atrial isoform " P35557 18 50979777-51031335 "Human disease related genes" "Tissue enriched" "Detected in some" 135 "heart: 414.0" "Not detected" "Not detected" "Cluster 49 - Heart contraction" "Variable (heart)" 8.6 6.7 8.5 3.0 19.2 8.7 13.8 3.1 6.7 11.3 15.8 10.2 16.4 7.4 11.9 16.7 7.5 5.7 6.6 14.1 10.4 12.9 7.3 10.1 6.0 8.3 12.0 6.1 16.6 7.4 2680.2 1690.6 442.0 12.4 5.1 7.7 4.8 2.3 5.9 13.7 11.0 1.4 9.6 20.1 14.2 8.5 5.3 6.0 5.0 6.1 5.0 12.4 9.0 7.8 4.8 8.4 8.7 2.5 11.4 23.9 4.5 5.7 5.5 6.2 4.2 10.4 21.6 6.9 3.0 4.6 9.3 4.6 7.1 9.3 6.4 5.5 5.8 6.8 12.9 4.4 7.9 7.5 5.8 7.2 6.3 7.8 5.1 15.2 37.0 6.8 10.8 12.0 5.2 8.6 14.6 6.9 6.7 4.6 GCM2 "GCMB, hGCMb" ENSSSCG00000035562 "one2one with ENSG00000124827" "Glial cells missing homolog 2" O75603 7 7564262-7570523 "Human disease related genes" "Low tissue specificity" "Detected in many" "Low region specificity" "Detected in many" "Cluster 50 - Muscle contraction" "Not variable" 0.8 0.7 0.7 0.0 0.4 1.3 0.4 0.2 0.5 0.2 0.7 1.7 0.1 0.6 0.2 0.7 0.8 0.4 0.4 1.2 0.3 0.6 1.2 1.0 0.4 0.7 0.5 0.8 2.0 0.5 1.2 0.9 0.7 0.4 0.2 0.7 0.2 0.1 0.5 1.3 0.4 0.3 0.9 0.4 0.2 0.1 0.4 0.4 0.4 0.3 0.5 0.7 0.2 0.5 0.2 0.7 0.5 0.2 0.3 0.8 0.3 0.4 0.4 0.8 0.3 0.1 0.6 0.5 0.2 0.7 0.6 0.6 1.3 0.0 1.0 0.4 0.8 0.1 0.2 0.4 0.6 0.4 0.3 0.4 0.5 1.0 0.2 0.5 0.6 0.3 0.2 0.3 0.6 0.5 0.8 0.5 0.7 0.3 GH1 "CS-2, CS-5, CSA, CSB, CSHP1, CSL, CSMT, FLJ75407, GH, GH-N, GHN, hCS-A, hCS-B, hCS-L, hGH-N, MGC149868, PL" ENSSSCG00000034212 "one2many with ENSG00000136488,ENSG00000204414,ENSG00000213218,ENSG00000259384" "Somatotropin " "P01241, P0DML2, P0DML3, Q14406" 12 15065024-15068818 "Human disease related genes" "Tissue enriched" "Detected in some" 330 "pituitary gland: 738.3" "Not detected" "Not detected" "Cluster 20 - Hormonal" "Variable (brain)" 7.3 9.1 12.7 2.9 6.0 9.6 13.1 3.8 9.8 10.6 21.9 12.0 20.2 12.2 11.6 16.8 12.8 9.5 8.9 12.6 10.6 14.6 8.9 11.7 9.4 7.9 16.1 5.7 14.1 8.8 5.9 4.0 3.9 9.9 5.5 11.4 5.3 0.9 8.0 13.8 11.9 1.9 13.8 6.9 12.9 10.1 7.1 7.0 8.0 7.3 8.3 22.6 9.4 11.3 7.0 38.9 11.5 3.3 31.1 22228.3 5.3 6.9 8.4 8.7 8.0 8.9 34.9 10.6 4.1 8.9 10.6 6.7 7.7 5.7 9.9 7.8 8.3 5.0 2.7 5.0 10.3 7.9 37.4 7.1 10.4 14.1 6.3 26.8 18.2 10.3 13.6 11.7 8.1 9.1 19.2 10.5 9.6 6.4 GHR GHBP ENSSSCG00000016866 "one2one with ENSG00000112964" "Growth hormone receptor precursor " P10912 16 27126352-27421449 "Human disease related genes" "Tissue enhanced" "Detected in many" "adipose tissue: 57.2;bone marrow: 51.3;liver: 42.1" "Low region specificity" "Detected in all" "Cluster 81 - Vasculature and connective tissue" "Variable (brain, lymphoid tissue)" 142.7 6.3 6.6 30.9 100.9 6.1 5.7 1.8 2.2 3.6 9.8 19.4 9.3 5.0 5.1 19.2 3.5 7.3 11.6 14.3 18.9 39.9 8.5 14.1 5.1 10.8 8.1 105.7 12.4 10.9 10.7 9.4 15.4 7.5 4.3 5.2 9.0 6.4 17.6 20.4 4.3 2.4 9.7 59.5 7.4 2.4 6.3 5.8 4.4 4.2 4.0 6.2 4.1 6.6 7.9 13.3 6.0 11.3 14.9 24.9 27.3 5.0 4.6 4.0 2.2 9.4 3.6 4.2 2.8 3.9 6.3 38.4 7.6 4.2 23.9 4.6 22.1 10.7 4.0 89.2 6.7 6.7 7.8 25.6 4.9 8.4 4.9 1.5 30.7 3.7 2.2 9.1 3.3 7.9 12.8 8.7 2.9 8.6 GHRH GHRF ENSSSCG00000007332 "one2one with ENSG00000118702" "Somatoliberin precursor " P01286 17 40387344-40397857 "Human disease related genes" "Tissue enhanced" "Detected in many" "brain: 11.2" "Low region specificity" "Detected in all" "Cluster 22 - Housekeeping transcription" "Not variable" 0.3 0.4 0.8 0.1 0.1 0.3 0.4 0.2 0.4 0.1 0.7 0.0 1.0 0.4 0.6 2.4 1.0 0.5 0.4 0.4 0.5 0.3 1.3 0.1 0.7 1.3 0.0 0.3 0.7 0.0 0.0 0.3 0.5 5.8 0.2 0.6 0.2 0.0 0.1 0.2 0.4 0.0 1.2 0.3 0.6 0.2 0.6 0.4 0.4 0.8 0.5 4.7 0.6 0.4 0.2 0.3 1.7 0.1 0.7 1.7 0.2 0.4 0.2 0.0 0.3 0.1 1.7 0.4 0.2 0.3 1.4 0.1 0.5 0.0 0.1 0.4 0.4 0.3 0.4 0.3 0.7 0.5 0.4 0.2 0.4 0.5 0.7 0.7 0.4 0.5 0.2 0.3 0.6 0.2 0.0 0.6 0.8 0.5 GHRHR ENSSSCG00000016673 "one2one with ENSG00000106128" "Growth hormone-releasing hormone receptor " Q02643 18 42029695-42046347 "Human disease related genes" "Tissue enriched" "Detected in some" 20 "pituitary gland: 29.1" "Not detected" "Not detected" "Cluster 20 - Hormonal" "Not variable" 0.0 0.0 0.1 0.1 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.4 0.0 0.3 0.0 0.0 0.1 0.0 0.3 1.1 0.1 0.1 0.1 0.0 0.2 0.0 0.2 0.0 0.1 0.6 0.3 0.0 0.1 0.1 0.3 0.1 0.0 0.0 0.0 0.2 0.0 0.2 0.3 0.1 0.0 0.1 0.1 0.0 0.4 34.3 0.1 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.3 0.0 0.2 0.0 0.2 0.1 0.3 0.2 0.0 0.2 0.0 0.0 0.0 GHRL "ghrelin, MTLRP, obestatin" ENSSSCG00000011568 "one2one with ENSG00000157017" "Appetite-regulating hormone precursor " Q9UBU3 13 66445858-66451150 "Human disease related genes" "Tissue enriched" "Detected in some" 23 "stomach: 70.6" "Not detected" "Not detected" "Cluster 64 - Gastrointestinal" "Not variable" 0.2 0.2 0.8 0.0 0.0 0.2 0.8 0.0 0.4 0.1 0.7 0.0 0.2 0.6 0.1 1.0 0.3 0.6 0.1 0.0 5.8 0.3 0.5 0.1 0.5 0.1 0.1 0.1 0.3 0.2 0.3 0.1 0.2 0.4 1.2 0.7 2.3 0.0 0.1 0.2 0.2 0.0 1.0 0.1 0.5 0.4 0.1 0.2 0.4 0.2 0.5 0.8 0.7 0.2 0.1 0.0 0.4 0.2 0.5 0.6 0.3 0.2 0.4 0.0 0.3 0.2 1.2 0.6 0.0 0.1 0.4 0.9 0.1 0.3 0.2 0.4 0.4 79.3 3.5 0.1 0.4 0.2 0.2 0.1 0.6 0.1 0.2 0.7 0.3 0.4 0.8 0.7 0.3 0.1 0.2 0.6 0.4 0.2 GLIS3 "MGC33662, ZNF515" ENSSSCG00000005224 "one2one with ENSG00000107249" "GLIS family zinc finger 3" Q8NEA6 1 217629320-218114862 "Human disease related genes" "Tissue enhanced" "Detected in many" "male glands: 75.0" "Low region specificity" "Detected in all" "Cluster 70 - Housekeeping" "Variable (brain, lymphoid tissue, male glands)" 12.0 2.4 20.5 10.0 7.4 9.7 26.0 58.6 17.9 7.4 25.4 28.5 172.1 20.7 10.4 7.5 20.2 23.2 19.3 44.4 38.5 22.1 49.7 42.6 14.9 37.3 46.5 10.8 93.0 66.0 8.8 8.7 4.7 25.6 6.6 21.2 10.9 15.0 32.2 61.9 28.5 0.3 12.7 10.5 26.6 9.2 20.9 22.1 16.5 18.2 9.5 14.5 33.2 12.1 42.4 19.2 46.9 9.6 22.5 35.5 11.6 17.2 21.9 119.6 6.7 12.2 13.1 18.3 9.5 138.6 25.7 2.9 8.4 7.4 57.8 10.5 11.6 7.6 3.7 5.1 25.1 19.2 18.5 24.9 16.6 8.4 16.9 4.0 94.6 11.1 8.7 59.4 30.2 32.9 12.7 27.0 12.5 26.4 GMPPA ENSSSCG00000023935 "one2one with ENSG00000144591" "Mannose-1-phosphate guanyltransferase alpha " Q96IJ6 15 121507581-121515298 "Human disease related genes" "Low tissue specificity" "Detected in all" "Low region specificity" "Detected in all" "Cluster 71 - Housekeeping regulation" "Not variable" 16.2 9.6 12.5 5.5 9.4 18.8 13.2 37.6 10.6 25.1 13.4 27.0 16.4 12.5 22.5 27.0 15.8 14.6 16.5 23.3 24.5 24.9 20.4 25.7 11.8 20.3 35.6 12.2 18.0 30.8 8.3 5.7 5.1 15.3 13.4 10.9 14.9 5.4 9.7 14.5 26.9 2.5 17.2 10.4 13.6 13.9 13.8 12.7 10.8 15.6 11.3 16.3 17.8 17.3 25.4 18.0 14.9 8.4 11.6 54.9 8.4 11.3 11.4 34.9 8.4 25.4 23.6 11.3 16.3 34.6 13.1 7.3 17.3 13.1 14.9 13.3 12.2 16.1 14.2 9.1 13.4 14.7 15.5 18.4 12.7 31.3 13.7 10.4 18.4 13.0 15.0 16.4 15.1 16.0 23.8 15.8 11.7 15.0 GNAS "GNAS1, GNASXL, GPSA, NESP, NESP55, SCG6, SgVI" ENSSSCG00000007520 "one2one with ENSG00000087460" "Guanine nucleotide-binding protein G(s) subunit alpha isoform f " "O95467, P63092, P84996, Q5JWF2" 17 58998981-59055340 "Human disease related genes" "Low tissue specificity" "Detected in all" "Low region specificity" "Detected in all" "Cluster 10 - Housekeeping transcription" "Not variable" 563.0 506.8 1104.9 258.4 413.0 291.4 445.4 440.3 631.2 374.7 831.0 644.4 935.8 933.0 424.4 492.5 904.0 1063.1 1189.8 661.4 374.5 640.2 294.8 731.0 833.5 593.4 541.3 485.4 534.2 573.2 220.5 188.7 222.6 2118.7 180.1 832.4 295.8 203.3 361.0 875.2 450.7 117.1 381.9 130.2 564.3 401.3 1338.2 1288.4 843.1 327.2 776.9 1409.0 453.9 392.1 582.2 439.5 1576.0 188.6 1779.7 2691.7 327.3 1379.7 873.2 362.0 507.7 430.4 649.8 873.6 251.7 280.4 1945.8 298.6 221.5 171.1 615.7 932.7 291.0 215.5 121.6 334.6 1121.7 1309.9 1344.1 520.0 910.2 249.3 1292.6 403.9 643.4 275.2 461.4 548.7 287.6 407.1 582.7 1362.5 882.4 931.1 GNRH1 "GNRH, GRH, LHRH" ENSSSCG00000009651 "one2one with ENSG00000147437" "Progonadoliberin-1 Gonadoliberin-1 GnRH-associated peptide 1" P01148 14 9442971-9447521 "Human disease related genes" "Tissue enriched" "Detected in many" 10 "brain: 42.5" "Group enriched" "Detected in some" 30 "basal ganglia: 14.6;hypothalamus: 42.5" "Cluster 64 - Gastrointestinal" "Variable (brain)" 0.6 1.2 0.7 0.1 0.5 0.4 2.1 0.0 1.1 1.9 0.6 0.2 0.2 0.5 1.4 4.4 1.0 0.6 1.4 0.2 2.3 2.1 0.8 0.2 0.3 0.0 1.2 0.1 0.6 1.1 0.6 0.3 0.2 66.0 1.5 0.4 1.1 0.2 0.4 1.0 0.4 1.3 1.3 0.2 1.8 0.1 1.2 0.7 0.4 0.1 0.2 1.3 0.3 1.1 3.5 0.2 0.7 0.9 0.2 0.6 1.1 0.3 0.5 0.4 0.8 2.1 0.6 0.4 0.2 0.4 21.7 0.2 0.1 0.7 0.6 0.4 2.4 1.4 0.7 0.1 0.4 1.3 0.2 0.6 0.6 0.4 0.5 1.9 1.4 1.1 0.2 0.6 0.3 0.2 0.2 0.7 0.7 0.9 GPR101 ENSSSCG00000040432 "one2one with ENSG00000165370" "G protein-coupled receptor 101" Q96P66 X 112108870-112144365 "Human disease related genes" "Tissue enriched" "Detected in single" 27 "brain: 22.3" "Low region specificity" "Detected in many" "Cluster 1 - Brain neurotransmission" "Not variable" 0.0 0.2 6.2 0.0 0.0 0.0 0.3 0.0 24.3 0.1 1.9 0.1 0.2 0.8 0.1 0.4 0.3 0.9 3.3 0.0 0.1 0.2 0.1 0.1 0.8 0.5 0.2 0.0 0.1 0.1 0.0 0.0 0.0 14.3 0.0 0.9 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.1 2.7 3.4 0.5 0.1 0.4 1.7 0.1 0.1 0.1 0.0 9.1 0.0 0.3 1.3 0.0 6.5 0.6 0.0 7.7 0.1 0.6 0.7 0.0 0.0 18.5 0.0 0.0 0.2 0.0 0.4 0.3 0.0 0.0 0.0 6.7 26.5 0.8 0.1 0.7 0.2 0.9 0.2 0.1 0.1 0.2 0.2 0.1 0.0 0.1 15.4 18.0 0.2 H6PD GDH ENSSSCG00000034502 "one2one with ENSG00000049239" "Hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase" O95479 6 69666378-69700298 "Human disease related genes" "Low tissue specificity" "Detected in all" "Low region specificity" "Detected in all" "Cluster 66 - Housekeeping mRNA" "Not variable" 52.0 36.3 12.1 7.3 15.5 27.1 28.9 25.3 10.0 31.0 17.1 55.0 25.1 9.3 27.1 45.5 9.3 10.5 11.3 25.4 39.5 20.3 13.0 43.5 9.1 22.7 29.9 32.3 40.8 27.5 14.4 11.1 14.0 12.5 18.5 10.3 21.7 2.1 15.1 24.7 33.1 2.6 30.7 42.0 36.1 14.8 9.0 8.5 7.8 35.9 6.9 16.1 42.8 29.1 34.5 17.9 12.1 11.5 11.0 22.3 14.8 8.0 8.2 27.6 6.8 30.2 17.5 9.1 17.2 18.6 11.3 12.9 16.6 9.0 21.5 8.5 12.7 20.1 26.5 22.6 11.7 9.6 11.4 25.9 8.9 13.0 8.3 79.6 23.4 25.7 19.6 46.7 22.7 22.7 24.3 12.2 9.6 9.6 HESX1 "ANF, RPX" ENSSSCG00000021207 "one2one with ENSG00000163666" "HESX homeobox 1" Q9UBX0 13 39044534-39088909 "Human disease related genes" "Low tissue specificity" "Detected in all" "Low region specificity" "Detected in all" "Cluster 22 - Housekeeping transcription" "Not variable" 2.6 2.6 3.6 0.7 1.5 3.0 3.2 1.6 3.1 2.1 4.6 4.6 5.1 3.6 2.3 5.8 6.9 3.9 5.0 3.1 2.7 4.0 3.0 4.3 2.9 2.0 4.3 2.2 5.9 2.3 1.5 1.0 1.2 5.4 1.5 3.2 1.4 0.4 2.4 4.9 3.6 1.0 4.0 2.5 3.1 2.4 4.8 4.4 2.8 2.7 2.7 5.3 3.9 2.4 1.6 2.1 6.0 0.5 6.0 6.4 1.0 4.1 2.7 3.6 2.8 2.4 5.9 3.6 0.8 1.5 4.4 1.4 2.1 1.1 3.5 2.9 2.0 1.1 0.9 1.8 3.8 4.8 3.8 1.8 2.9 10.5 3.7 5.0 3.9 2.6 2.9 4.2 3.2 2.7 4.3 4.2 3.6 4.5 HHEX "HEX, HOX11L-PEN, PRHX" ENSSSCG00000036314 "one2one with ENSG00000152804" "Hematopoietically-expressed homeobox protein HHEX " Q03014 14 104194319-104204017 "Human disease related genes" "Tissue enhanced" "Detected in many" "thyroid gland: 19.5" "Low region specificity" "Detected in many" "Cluster 77 - Housekeeping defense" "Variable (lymphoid tissue, upper respiratory system)" 3.4 4.0 1.3 2.1 4.4 4.1 4.1 0.5 1.0 2.4 0.7 1.4 1.0 1.1 2.9 0.4 1.9 1.1 2.3 1.8 2.6 5.1 3.2 1.4 0.9 0.2 2.3 2.7 1.2 12.6 1.0 0.9 0.8 2.2 1.3 0.9 3.2 0.0 0.6 2.7 1.1 0.0 3.6 5.5 6.1 8.5 1.9 1.7 0.9 2.2 0.7 1.2 5.8 2.4 2.4 4.4 2.1 1.3 3.3 0.6 3.0 1.7 0.9 0.5 1.1 2.6 0.6 0.9 0.2 0.3 1.8 1.0 1.6 1.4 1.7 0.8 4.0 1.1 1.3 2.3 1.3 2.2 1.7 3.7 1.0 2.6 1.7 1.3 20.6 1.5 8.2 3.4 0.8 1.5 2.4 1.2 1.3 1.7 HNF1A "HNF1, LFB1, MODY3, TCF1" ENSSSCG00000009919 "one2one with ENSG00000135100" "Hepatocyte nuclear factor 1-alpha " 14 40868205-40890469 "Human disease related genes" "Tissue enhanced" "Detected in some" "kidney: 44.0;liver: 42.4;small intestine: 18.9;stomach: 31.4" "Not detected" "Not detected" "Cluster 64 - Gastrointestinal" "Variable (kidney)" 0.1 0.1 0.2 0.0 0.1 0.2 0.2 0.0 0.2 23.9 0.6 0.5 0.0 0.3 20.8 0.2 0.3 0.2 0.1 0.1 34.4 0.1 0.6 1.3 0.2 0.0 0.1 0.0 0.2 23.0 0.1 0.1 0.1 0.2 22.5 0.2 20.6 0.0 61.8 3.4 0.1 0.0 0.7 40.0 0.1 0.1 0.1 0.1 0.1 0.1 0.2 0.6 0.2 0.2 0.0 0.2 0.2 0.0 0.1 0.1 0.1 0.1 0.1 0.0 0.1 17.8 0.3 0.2 0.0 0.0 0.1 0.3 0.1 0.1 0.6 0.2 0.1 21.0 32.9 0.1 0.2 0.2 0.1 0.4 0.2 0.4 0.0 0.1 0.1 0.3 0.1 0.1 0.2 0.1 0.2 0.2 0.1 0.1 HNF1B "HNF1beta, LFB3, MODY5, TCF2, VHNF1" ENSSSCG00000022417 "one2one with ENSG00000275410" "Hepatocyte nuclear factor 1-beta " P35680 12 39143121-39201601 "Human disease related genes" "Tissue enhanced" "Detected in many" "gallbladder: 24.5;kidney: 75.6" "Not detected" "Not detected" "Cluster 65 - Epithelium" "Variable (upper respiratory system)" 0.3 2.4 0.8 0.2 0.1 1.4 16.4 11.1 0.3 38.0 0.1 1.1 0.2 0.6 35.8 0.2 0.6 0.3 0.4 14.5 38.5 0.0 1.0 16.7 0.7 40.5 0.7 0.2 43.8 72.1 0.1 0.0 0.1 2.9 24.9 0.7 22.6 0.2 141.6 157.1 6.8 2.8 0.2 9.2 17.9 0.2 0.3 0.4 0.3 1.7 0.1 0.2 2.2 0.4 0.3 0.6 1.6 0.0 0.0 0.3 0.0 0.5 0.8 33.9 0.1 43.5 0.4 0.2 13.3 26.9 1.2 0.0 1.6 0.1 0.2 0.1 0.1 16.5 24.1 0.3 1.0 0.2 0.2 0.9 0.8 8.4 0.3 0.2 1.9 0.2 0.3 18.1 17.4 22.9 0.3 1.0 0.3 0.4 HNF4A "HNF4, MODY, MODY1, NR2A1, TCF14" ENSSSCG00000007371 "one2one with ENSG00000101076" "Hepatocyte nuclear factor 4-alpha " P41235 17 46783777-46847500 "Human disease related genes" "Tissue enhanced" "Detected in some" "kidney: 56.6;large intestine: 36.1;liver: 68.3;small intestine: 31.8;stomach: 61.7" "Not detected" "Not detected" "Cluster 64 - Gastrointestinal" "Variable (kidney)" 0.1 0.3 0.0 0.1 0.3 0.0 0.2 0.0 0.0 132.7 0.0 0.1 50.9 0.0 114.3 0.0 0.1 0.0 0.0 0.0 89.4 0.0 0.0 0.0 0.0 4.0 0.0 0.3 1.1 58.6 0.0 0.0 0.0 0.0 64.5 0.0 52.2 0.0 135.3 8.7 0.1 0.0 0.1 109.8 0.2 0.0 0.8 0.1 0.0 0.0 0.0 0.0 0.2 0.8 0.0 0.0 0.1 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.0 95.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 75.7 110.0 0.1 0.0 0.2 1.4 0.0 0.0 0.4 0.3 0.0 0.0 0.2 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 HS6ST1 HS6ST ENSSSCG00000022197 "one2one with ENSG00000136720" "Heparan sulfate 6-O-sulfotransferase 1" O60243 15 59066613-59108772 "Human disease related genes" "Low tissue specificity" "Detected in all" "Low region specificity" "Detected in all" "Cluster 5 - Intracellular signalling" "Not variable" 15.7 14.7 22.3 5.7 21.9 18.5 23.1 7.3 16.5 14.2 27.1 13.7 34.8 28.1 13.1 48.2 12.0 21.7 18.7 14.2 8.5 25.3 9.0 20.2 28.6 6.4 11.8 10.3 26.3 19.3 4.7 4.3 5.6 22.2 7.3 26.7 7.3 3.3 13.4 68.3 18.7 3.9 15.6 14.0 30.8 15.3 20.3 22.2 26.0 17.2 28.2 34.7 32.4 21.4 46.5 13.8 20.1 5.2 19.7 18.1 14.7 23.6 26.8 12.2 13.3 11.5 22.1 28.4 10.6 9.6 19.4 14.1 11.9 3.5 7.6 31.8 12.4 7.8 14.7 6.3 32.4 21.2 26.6 13.6 29.0 3.4 23.8 31.6 39.5 8.7 11.6 26.4 13.9 17.7 23.3 26.3 17.7 14.7 HSD11B1 "HSD11, HSD11B, SDR26C1" ENSSSCG00000015616 "one2one with ENSG00000117594" "Hydroxysteroid 11-beta dehydrogenase 1" P28845 9 133229659-133278531 "Human disease related genes" "Tissue enhanced" "Detected in all" "lens: 85.8;liver: 92.3" "Low region specificity" "Detected in all" "Cluster 33 - Lens" "Variable (male glands)" 32.4 5.5 16.5 11.6 14.2 30.2 38.5 30.5 24.1 6.8 16.4 15.5 33.1 15.6 8.7 66.0 15.4 41.2 33.6 8.4 19.4 27.6 9.4 17.4 15.3 15.3 10.2 7.5 45.8 16.3 8.6 6.1 5.2 19.8 5.3 14.2 9.6 1.2 4.6 9.3 9.6 78.0 12.1 143.9 63.8 12.3 25.5 18.4 14.1 13.3 14.1 23.8 29.8 15.7 18.8 6.3 19.7 7.1 18.2 166.6 11.3 21.0 12.6 6.4 28.3 10.8 25.9 17.1 4.0 5.6 21.2 10.1 6.5 3.7 24.6 13.9 5.7 13.3 6.0 10.2 18.0 29.6 26.9 66.7 13.0 8.3 18.0 15.8 21.9 7.2 13.4 21.2 7.4 9.8 16.0 29.5 17.7 37.0 IFIH1 "Hlcd, IDDM19, MDA-5, MDA5" ENSSSCG00000015897 "one2one with ENSG00000115267" "Interferon-induced helicase C domain-containing protein 1 " Q9BYX4 15 68928254-68985492 "Human disease related genes" "Low tissue specificity" "Detected in all" "Low region specificity" "Detected in all" "Cluster 77 - Housekeeping defense" "Not variable" 10.5 6.2 7.1 4.1 11.5 9.0 16.5 3.2 5.8 21.4 10.4 10.6 17.1 7.1 22.0 10.9 7.7 5.5 6.7 8.8 13.0 22.6 8.0 11.8 6.0 3.8 12.0 7.8 18.3 11.8 5.8 5.8 4.5 6.8 16.9 6.5 12.6 1.1 5.0 14.4 10.0 1.8 13.2 11.3 18.4 21.3 4.9 4.7 4.5 9.0 4.9 14.1 13.4 10.4 9.3 9.2 7.0 3.5 12.4 18.6 6.2 3.9 5.3 4.2 3.8 16.9 15.8 6.5 3.8 4.6 6.4 5.5 6.3 4.9 9.7 4.9 17.6 9.2 10.1 5.9 6.4 6.3 5.5 9.1 6.3 6.5 4.3 19.7 11.7 10.2 28.2 15.4 5.1 7.6 14.4 5.8 5.5 5.1 IGF1 "IGF-I, IGF1A, IGFI" ENSSSCG00000000857 "one2one with ENSG00000017427" "Insulin-like growth factor I precursor " P05019 5 81776422-81848048 "Human disease related genes" "Tissue enhanced" "Detected in many" "adipose tissue: 73.1" "Low region specificity" "Detected in many" "Cluster 76 - Housekeeping regulation" "Variable (adipose tissue, brain, kidney)" 37.8 2.9 3.8 16.8 81.4 7.6 5.1 21.0 1.2 23.2 0.7 39.5 5.7 5.0 28.9 25.6 0.8 5.9 7.2 73.7 9.3 78.8 16.9 183.7 5.5 19.4 8.7 137.5 19.2 34.7 18.0 12.9 9.9 1.8 6.7 5.1 10.8 1.2 1.0 9.6 6.2 0.0 33.8 6.1 8.3 5.8 2.3 2.7 3.7 15.2 2.3 14.8 27.8 16.5 32.7 36.9 1.7 20.8 5.8 5.0 19.0 3.5 4.4 31.0 1.5 21.5 12.9 5.0 4.3 21.4 1.9 18.5 11.9 6.1 18.0 2.9 3.4 7.6 7.7 38.0 4.5 2.5 4.7 47.1 4.3 48.0 2.3 2.3 34.1 25.5 5.4 9.1 42.5 13.2 12.1 7.2 4.7 4.8 IGF2BP2 IMP-2 ENSSSCG00000011795 "one2one with ENSG00000073792" "Insulin like growth factor 2 mRNA binding protein 2" Q9Y6M1 13 123485623-123650043 "Human disease related genes" "Low tissue specificity" "Detected in all" "Low region specificity" "Detected in all" "Cluster 71 - Housekeeping regulation" "Not variable" 5.6 4.0 2.8 3.9 8.2 4.3 14.5 8.3 2.6 34.3 2.3 7.5 4.9 2.1 34.5 3.2 2.2 2.6 5.7 15.6 21.7 18.6 8.4 22.5 2.1 20.3 16.9 8.2 22.6 31.7 5.1 4.5 3.8 3.1 22.4 1.9 22.2 1.2 15.9 14.3 10.7 6.1 13.4 1.8 18.1 1.3 3.5 2.6 1.6 6.1 1.8 5.9 10.8 10.3 1.5 6.4 4.5 2.3 4.1 10.6 4.5 2.6 1.6 13.4 2.5 25.1 35.8 1.8 6.4 8.0 2.7 5.0 7.4 4.0 8.6 1.9 2.7 9.8 10.4 5.4 2.9 3.6 5.5 8.0 2.3 6.0 2.5 1.6 9.7 8.0 5.0 17.7 9.7 5.6 13.2 2.7 2.1 4.3 IGFALS ALS ENSSSCG00000008013 "one2one with ENSG00000099769" "Insulin-like growth factor-binding protein complex acid labile subunit precursor " P35858 3 40174764-40177787 "Human disease related genes" "Tissue enriched" "Detected in many" 5 "liver: 47.0" "Not detected" "Not detected" "Cluster 66 - Housekeeping mRNA" "Variable (male glands)" 5.7 3.4 1.0 1.1 2.3 4.8 7.0 1.6 0.7 2.1 1.7 4.5 1.1 0.7 2.6 3.6 2.3 0.9 1.8 4.8 3.4 5.2 3.3 4.1 0.6 4.5 4.2 6.5 3.4 5.2 1.8 1.6 0.9 1.4 3.1 1.2 3.5 1.0 4.1 2.3 2.9 0.2 5.8 28.2 7.7 7.2 1.2 0.9 0.6 2.3 0.6 1.8 4.3 4.1 2.1 4.3 1.2 3.4 1.2 1.9 2.9 0.8 0.7 5.3 0.7 3.4 3.2 0.8 5.0 2.8 1.2 0.8 3.9 3.5 2.9 0.8 3.1 2.5 3.6 4.1 1.0 1.5 1.3 3.1 0.8 1.4 1.0 7.6 4.7 2.4 9.1 2.4 2.8 5.0 6.7 1.0 1.1 1.3 IGSF1 "IGCD1, IGDC1, INHBP, KIAA0364, MGC75490, PGSF2" ENSSSCG00000012667 "one2one with ENSG00000147255" "Immunoglobulin superfamily member 1" Q8N6C5 X 107674208-107691098 "Human disease related genes" "Tissue enriched" "Detected in some" 9 "pituitary gland: 94.6" "Low region specificity" "Detected in many" "Cluster 1 - Brain neurotransmission" "Variable (brain)" 0.6 6.5 10.2 0.3 0.2 0.1 0.0 0.2 11.0 0.0 3.6 0.1 0.5 6.5 0.1 0.1 4.0 6.6 6.3 1.6 0.1 0.1 0.3 2.5 6.6 0.3 0.1 0.1 0.1 0.3 4.5 3.8 6.7 35.5 0.0 6.7 0.0 0.1 1.9 0.5 0.1 0.0 1.1 0.0 0.1 0.4 9.0 11.8 6.3 0.0 6.7 5.4 0.1 0.7 0.0 1.1 16.8 0.0 0.9 368.2 0.1 14.2 5.2 0.0 9.1 0.2 0.4 6.6 0.0 0.0 17.1 1.0 0.0 0.0 0.0 7.1 0.4 0.0 0.0 0.3 9.5 14.8 13.7 1.0 7.3 0.2 14.9 1.4 0.0 0.4 0.3 0.1 0.6 0.1 0.1 9.4 11.5 6.6 IL17RD "FLJ35755, IL-17RD, IL17RLM, SEF" ENSSSCG00000011463 "one2one with ENSG00000144730" "Interleukin 17 receptor D" Q8NFM7 13 38939402-39006690 "Human disease related genes" "Tissue enhanced" "Detected in many" "pituitary gland: 26.0" "Low region specificity" "Detected in all" "Cluster 12 - Metabolic" "Variable (cartilage, male glands)" 6.5 2.4 6.2 1.9 2.4 7.0 1.9 1.7 6.8 1.2 13.3 10.3 5.9 5.9 1.1 15.3 6.7 6.8 8.0 9.8 1.0 3.8 7.7 12.2 4.9 1.0 5.7 10.1 17.5 7.9 4.5 3.4 2.5 6.2 0.5 5.4 1.1 0.2 0.8 1.1 2.9 0.3 9.3 0.2 2.7 0.9 6.3 5.2 4.8 6.6 3.6 12.8 7.6 7.3 6.3 9.5 7.0 1.7 8.4 41.9 4.3 3.0 5.9 8.2 3.9 1.3 1.9 5.7 2.0 1.1 9.8 4.2 2.8 0.7 3.2 4.4 0.5 1.2 0.6 5.7 8.1 5.2 3.4 9.0 4.8 2.7 2.7 0.5 1.6 6.1 1.4 3.4 4.6 5.3 25.2 7.4 5.6 7.6 IL2 "IL-2, TCGF" ENSSSCG00000033267 "one2one with ENSG00000109471" "Interleukin-2 " P60568 8 101640168-101649714 "Human disease related genes" "Low tissue specificity" "Detected in all" "Low region specificity" "Detected in all" "Cluster 40 - Testis" "Not variable" 2.1 1.9 3.0 0.6 1.0 1.8 2.7 0.7 2.0 2.3 4.1 3.3 6.3 2.6 2.5 4.1 3.8 2.3 1.8 2.9 3.7 4.3 1.1 2.8 2.2 2.5 3.2 1.4 3.0 2.0 1.3 1.0 1.0 2.5 1.2 2.9 1.4 0.1 1.6 3.0 2.4 0.7 2.3 3.8 3.0 2.5 1.8 1.7 1.9 1.5 1.7 5.5 2.3 1.7 2.5 1.6 2.6 0.7 2.9 2.7 1.2 1.3 2.2 1.8 1.5 2.2 6.3 2.7 0.8 1.8 2.3 1.3 1.8 0.8 1.7 1.7 1.9 1.2 0.8 1.3 2.5 2.1 1.5 1.1 2.4 12.0 1.6 6.2 3.0 1.9 4.4 2.1 1.8 2.1 4.0 2.4 2.1 1.5 IL21 "IL-21, Za11" ENSSSCG00000009087 "one2one with ENSG00000138684" "Interleukin-21 precursor " Q9HBE4 8 101530949-101540712 "Human disease related genes" "Tissue enhanced" "Detected in some" "liver: 18.7;lymphoid tissue: 12.5" "Not detected" "Not detected" "Cluster 82 - Lymphoid B cell" "Variable (lymphoid tissue)" 0.0 0.0 0.3 0.0 0.1 0.0 1.1 0.0 0.0 1.5 0.0 0.0 0.0 0.2 1.7 0.0 0.0 0.3 0.0 0.0 2.2 0.0 0.0 0.0 0.3 0.1 0.9 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.8 0.1 1.1 0.0 0.0 0.2 0.1 0.0 0.0 5.5 2.2 2.8 0.0 0.0 0.2 0.7 0.3 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 1.5 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 1.0 1.0 0.0 0.0 0.0 0.0 0.0 0.3 1.1 0.0 0.3 0.0 0.0 8.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 IL2RA "CD25, IDDM10, IL2R" ENSSSCG00000022849 "one2one with ENSG00000134460" "Interleukin-2 receptor subunit alpha precursor " P01589 10 64948517-65001142 "Human disease related genes" "Tissue enhanced" "Detected in many" "lymphoid tissue: 23.3" "Low region specificity" "Detected in some" "Cluster 79 - Lymphoid myeloid" "Not variable" 3.8 0.4 0.5 1.1 1.6 0.8 4.2 0.2 0.7 6.0 2.6 1.1 1.1 0.5 7.9 2.1 0.4 0.5 0.6 1.2 4.0 1.7 0.8 1.6 0.4 1.0 3.0 5.2 2.2 2.6 0.5 0.7 0.4 0.9 3.4 0.5 3.5 0.0 0.5 4.3 2.4 0.1 6.1 0.2 4.1 19.0 0.5 0.7 0.4 2.5 0.4 1.0 5.2 4.4 1.1 0.7 0.8 0.5 1.4 1.9 0.9 0.5 0.4 0.9 0.5 4.9 3.1 0.5 0.7 1.3 0.7 0.9 1.5 2.8 0.8 0.4 4.3 2.2 4.1 2.9 0.5 0.5 1.7 1.7 0.5 1.0 1.3 12.7 0.8 2.2 18.6 3.4 1.0 1.0 1.3 0.5 0.6 0.5 INS "IDDM1, IDDM2" ENSSSCG00000033740 "one2one with ENSG00000254647" "Insulin Insulin B chain Insulin A chain" P01308 2 1496842-1497841 "Human disease related genes" "Tissue enriched" "Detected in some" 12 "adrenal gland: 25.3" "Region enriched" "Detected in single" 13 "midbrain: 2.1" "Cluster 20 - Hormonal" "Not variable" 0.2 13.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 INSR CD220 ENSSSCG00000013566 "one2one with ENSG00000171105" "Insulin receptor" P06213 2 71797125-71936215 "Human disease related genes" "Low tissue specificity" "Detected in all" "Low region specificity" "Detected in all" "Cluster 70 - Housekeeping" "Not variable" 44.3 33.9 17.7 9.7 23.0 27.6 25.8 22.7 9.4 22.7 31.7 120.8 58.6 16.4 29.1 28.0 21.0 14.5 17.4 39.3 23.4 37.0 15.9 48.7 15.7 9.5 28.1 27.3 55.4 29.6 15.7 13.0 21.4 19.5 12.0 16.5 15.8 5.7 73.2 48.9 33.8 12.2 20.3 34.0 27.7 8.9 17.2 16.9 13.8 23.1 14.2 27.1 22.0 19.0 29.5 22.2 18.3 10.0 15.4 31.3 16.8 15.7 14.1 34.0 9.5 30.7 34.7 16.3 16.9 17.3 15.8 22.3 12.3 9.7 40.8 16.5 13.5 26.9 29.7 26.8 17.8 18.7 22.6 19.4 16.3 18.5 16.9 30.2 32.6 14.1 9.8 41.9 27.8 34.3 40.2 17.6 13.1 14.8 ITPR3 IP3R3 ENSSSCG00000001518 "one2one with ENSG00000096433" "Inositol 1,4,5-trisphosphate receptor type 3" Q14573 7 29835869-29902160 "Human disease related genes" "Tissue enhanced" "Detected in many" "stomach: 78.1" "Low region specificity" "Detected in some" "Cluster 75 - Housekeeping" "Variable (brain)" 16.4 11.2 1.8 4.5 6.8 19.8 20.0 8.2 1.7 47.1 1.7 5.6 2.7 2.0 40.9 46.2 2.9 1.5 14.4 18.5 21.1 14.5 19.0 47.2 2.0 10.4 23.2 5.0 23.7 85.6 4.7 5.7 2.4 2.7 15.2 2.2 14.5 1.3 3.6 15.9 48.6 1.0 29.6 3.2 16.1 18.1 3.8 4.1 1.9 29.3 1.6 16.2 35.7 15.3 8.5 30.6 2.0 8.1 2.8 8.6 14.3 2.5 1.7 11.1 1.6 33.0 1.0 2.0 8.5 4.7 2.1 2.0 17.1 18.0 4.7 2.1 4.8 72.5 107.0 4.5 2.0 5.6 6.2 13.8 2.0 13.8 2.7 23.5 10.6 18.0 20.3 30.5 10.7 11.8 107.9 2.1 2.0 6.9 IYD "C6orf71, DEHAL1, dJ422F24.1" ENSSSCG00000004093 "one2one with ENSG00000009765" "Iodotyrosine deiodinase 1 precursor " Q6PHW0 1 15757679-15779492 "Human disease related genes" "Tissue enriched" "Detected in many" 12 "thyroid gland: 295.1" "Low region specificity" "Detected in many" "Cluster 51 - Liver and kidney" "Variable (male glands)" 5.2 6.7 9.5 2.4 3.7 7.9 37.9 2.2 7.1 19.0 15.1 9.1 15.3 9.2 23.7 28.6 8.8 6.4 4.5 7.7 16.7 10.9 6.3 8.5 7.8 19.7 10.3 5.3 9.9 46.7 5.1 5.0 4.9 6.5 13.3 9.2 10.9 0.6 44.1 49.4 8.0 1.2 11.6 92.0 54.4 5.7 4.4 4.5 6.3 4.8 6.8 17.4 7.3 8.4 4.5 6.4 7.0 1.9 11.6 9.4 4.1 3.5 7.1 5.4 4.5 12.1 26.3 8.8 3.5 5.0 7.0 7.0 5.8 5.5 6.9 6.9 6.6 3.9 2.8 6.7 7.7 5.4 4.0 5.3 8.3 12.2 4.3 18.7 2956.9 10.1 8.0 8.8 7.0 6.4 11.7 7.8 6.8 4.2 JAZF1 "DKFZp761K2222, TIP27, ZNF802" ENSSSCG00000016691 "one2one with ENSG00000153814" "JAZF zinc finger 1 " Q86VZ6 18 44487997-44827657 "Human disease related genes" "Tissue enhanced" "Detected in many" "lens: 89.3" "Low region specificity" "Detected in all" "Cluster 12 - Metabolic" "Variable (lymphoid tissue)" 52.3 7.2 49.2 24.9 21.2 25.1 20.8 8.9 42.5 9.6 53.8 171.1 32.6 61.5 11.6 36.0 33.3 60.9 28.2 113.1 11.3 25.5 22.4 189.7 56.0 22.1 29.0 50.9 54.2 50.4 15.0 11.9 16.6 55.7 8.8 51.9 17.4 5.9 16.7 13.0 14.1 72.1 41.5 0.9 27.6 12.8 29.8 36.3 52.5 21.8 57.3 44.8 28.7 25.4 33.0 58.4 37.9 24.0 28.2 82.2 29.9 34.7 55.6 5.0 35.5 17.9 20.5 57.1 5.5 14.9 47.8 12.9 21.2 23.0 83.0 63.3 17.7 7.5 6.1 29.9 54.3 33.2 33.6 35.7 56.4 34.0 38.3 9.3 49.3 30.7 17.0 34.9 10.0 64.6 24.0 60.5 38.9 23.5 KCNJ1 "Kir1.1, ROMK1" ENSSSCG00000015236 "one2one with ENSG00000151704" "Potassium voltage-gated channel subfamily J member 1" P48048 9 55780257-55785577 "Human disease related genes" "Tissue enriched" "Detected in single" 108 "kidney: 62.1" "Not detected" "Not detected" "Cluster 39 - Kidney transport" "Not variable" 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 68.6 157.7 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 KCNJ5 "CIR, GIRK4, KATP1, Kir3.4, LQT13" ENSSSCG00000021573 "one2one with ENSG00000120457" "G protein-activated inward rectifier potassium channel 4 " P48544 9 55836701-55864941 "Human disease related genes" "Tissue enhanced" "Detected in many" "adrenal gland: 36.1;epididymis: 18.1;heart: 66.5" "Low region specificity" "Detected in all" "Cluster 3 - Brain cellular structure" "Variable (adipose tissue, brain, male glands)" 5.7 67.8 11.8 0.2 2.6 0.4 0.5 0.2 1.5 0.5 6.5 1.3 0.8 7.3 0.7 1.5 7.5 12.9 11.5 2.2 2.2 3.4 0.3 16.1 9.1 29.9 0.5 0.3 14.5 0.5 71.7 29.9 24.5 7.7 0.4 6.9 0.8 0.0 4.7 28.1 0.6 0.1 0.7 0.2 0.8 0.5 16.1 8.4 8.0 0.4 8.4 17.8 1.2 0.5 4.8 0.5 3.8 1.3 2.0 50.0 0.8 6.9 7.5 0.3 4.1 0.6 5.4 7.5 0.1 5.6 7.4 0.5 0.4 0.2 1.2 9.9 0.4 0.5 0.4 0.2 11.1 5.4 7.0 0.6 10.9 0.5 12.0 1.7 0.5 0.6 0.5 0.8 0.3 0.3 0.6 12.5 6.5 14.6 KCNQ1 "JLNS1, KCNA8, KCNA9, Kv7.1, KVLQT1, LQT, LQT1" ENSSSCG00000039556 "one2one with ENSG00000053918" "Potassium voltage-gated channel subfamily Q member 1" P51787 2 1675304-1989503 "Human disease related genes" "Tissue enhanced" "Detected in many" "adrenal gland: 44.5;kidney: 34.7;male glands: 35.3;stomach: 54.3" "Not detected" "Not detected" "Cluster 69 - Housekeeping" "Variable (upper respiratory system)" 3.4 96.3 1.3 2.1 6.5 5.1 12.4 72.1 0.7 62.3 0.8 2.6 0.6 1.1 59.3 1.3 1.6 0.9 1.7 3.2 63.0 5.2 3.7 8.5 1.0 1.5 14.9 4.0 18.9 83.2 22.4 12.6 16.0 1.2 30.4 1.5 27.6 0.5 64.7 49.2 23.9 0.0 3.3 9.3 11.3 0.7 1.2 0.9 1.0 5.1 0.9 1.0 7.0 3.5 57.2 2.5 1.1 1.2 0.5 1.6 3.4 0.9 1.1 17.1 0.4 42.9 0.8 1.2 7.7 15.7 0.8 0.3 5.6 2.8 1.1 1.0 1.1 36.9 75.4 3.2 1.1 1.1 0.9 4.2 1.2 69.6 1.0 1.6 3.9 2.5 1.9 23.6 18.4 11.7 2.5 1.1 0.8 1.6 KISS1 ENSSSCG00000038350 "one2one with ENSG00000170498" "Metastasis-suppressor KiSS-1 precursor " Q15726 9 64834824-64853609 "Human disease related genes" "Low tissue specificity" "Detected in all" "Low region specificity" "Detected in all" "Cluster 44 - Housekeeping" "Not variable" 1.5 1.8 2.9 0.7 1.3 2.4 2.6 0.9 2.2 3.2 4.9 3.0 4.1 2.5 3.1 5.0 3.2 1.9 1.8 2.6 3.9 3.3 2.0 3.7 2.1 1.5 3.0 1.3 3.3 2.0 1.3 0.8 0.8 2.3 2.6 2.6 2.4 0.1 1.9 2.5 2.3 0.3 2.8 2.8 2.6 1.9 1.6 1.6 1.6 1.4 1.9 5.1 1.9 2.1 1.4 1.9 2.2 0.6 3.6 3.0 1.2 1.3 2.0 2.2 1.5 2.5 7.6 2.6 0.9 1.6 2.2 1.2 1.4 1.2 2.3 1.9 1.9 1.9 1.3 1.0 2.3 1.8 1.5 1.4 2.3 1.9 1.4 5.5 5.3 1.8 2.7 2.4 1.5 1.9 3.2 2.4 2.1 1.6 KISS1R "AXOR12, GPR54, HOT7T175" ENSSSCG00000013420 "one2one with ENSG00000116014" "KiSS-1 receptor " Q969F8 2 77472362-77479204 "Human disease related genes" "Tissue enhanced" "Detected in some" "brain: 5.4" "Low region specificity" "Detected in all" "Cluster 1 - Brain neurotransmission" "Not variable" 0.0 0.2 0.3 0.0 0.0 0.1 0.0 0.0 0.3 0.0 1.8 0.1 0.6 0.6 0.0 0.2 0.3 0.4 0.4 0.2 0.0 0.1 0.0 0.2 0.3 0.4 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.8 0.0 0.6 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.6 0.6 0.5 0.1 0.3 0.9 0.2 0.0 0.1 0.0 1.0 0.0 0.2 0.5 0.0 0.8 0.4 0.0 0.2 0.0 1.0 0.5 0.0 0.0 0.8 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.1 0.4 0.5 0.6 0.0 0.5 0.0 0.7 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.4 0.3 0.4 KLF11 "MODY7, TIEG2, Tieg3" ENSSSCG00000038643 "one2one with ENSG00000172059" "Krueppel-like factor 11 " O14901 3 126416529-126429910 "Human disease related genes" "Low tissue specificity" "Detected in all" "Low region specificity" "Detected in all" "Cluster 81 - Vasculature and connective tissue" "Not variable" 21.9 8.2 5.1 7.2 12.6 9.0 8.1 2.9 6.7 3.7 13.6 22.9 5.9 6.8 5.1 17.9 4.4 4.1 6.6 6.5 6.0 15.2 5.4 8.6 6.5 3.3 5.4 12.8 9.0 6.4 4.4 3.4 4.2 7.1 2.1 6.5 2.8 0.7 8.3 16.8 3.8 1.8 10.0 3.0 9.4 4.3 5.1 7.1 5.7 3.0 6.7 10.1 2.7 5.6 8.9 7.5 7.6 6.2 12.0 5.4 8.8 5.2 5.9 3.6 4.9 3.8 10.7 6.0 3.6 2.6 5.8 7.0 4.6 3.5 11.7 8.0 3.3 3.8 1.7 7.9 5.5 5.6 8.7 8.7 6.7 17.5 6.9 3.1 13.2 5.1 3.4 4.9 4.4 6.6 21.5 5.0 5.9 4.4 LDLR LDLCQ2 ENSSSCG00000028512 "one2one with ENSG00000130164" "Low-density lipoprotein receptor precursor " P01130 2 69828332-69864819 "Human disease related genes" "Tissue enhanced" "Detected in many" "adrenal gland: 153.0;ovary: 76.4" "Low region specificity" "Detected in all" "Cluster 71 - Housekeeping regulation" "Variable (brain)" 23.9 562.3 16.9 21.2 26.1 13.1 50.7 21.0 7.4 54.8 9.1 8.4 5.5 15.7 41.8 116.2 42.4 14.4 45.4 18.0 34.2 29.3 24.2 31.3 13.7 3.7 37.9 20.5 15.6 81.1 12.9 11.7 8.1 25.3 25.8 16.3 22.5 4.8 6.9 36.6 19.9 2.6 40.1 48.7 55.8 24.3 34.4 23.8 13.3 21.0 12.1 17.5 25.3 34.2 351.1 42.7 30.1 7.6 15.2 5.1 36.6 26.2 13.7 13.7 6.7 59.4 5.4 15.9 6.1 6.3 15.8 5.8 22.9 28.5 12.2 12.8 16.8 42.4 39.5 30.3 18.4 30.5 25.6 17.9 13.5 239.5 22.4 15.8 21.5 32.3 22.9 42.2 8.6 59.1 98.0 19.2 13.0 45.0 LEP "OB, OBS" ENSSSCG00000040464 "one2one with ENSG00000174697" "Leptin precursor " P41159 18 20106179-20123451 "Human disease related genes" "Group enriched" "Detected in some" 4 "adipose tissue: 22.8;aorta: 24.7;bone marrow: 23.7;testis: 14.5" "Not detected" "Not detected" "Cluster 81 - Vasculature and connective tissue" "Not variable" 9.1 0.2 0.4 10.4 19.2 0.5 0.4 0.0 0.4 0.6 0.5 0.8 0.5 0.4 0.7 0.6 0.2 0.3 0.2 0.6 0.2 0.4 0.6 0.7 0.3 0.2 0.5 18.9 0.9 1.6 0.2 0.1 0.0 0.3 0.1 0.3 0.1 0.0 1.0 0.5 0.4 0.0 0.6 0.5 0.4 0.3 0.1 0.2 0.2 0.2 0.2 0.8 0.3 0.6 0.3 0.3 0.3 0.1 0.1 0.4 3.5 0.1 0.2 0.2 0.2 0.8 0.4 0.3 0.2 0.1 0.3 0.1 1.0 0.2 0.3 0.2 0.3 0.1 0.0 12.7 0.3 0.2 0.1 0.5 0.2 22.6 0.1 0.4 0.4 0.4 0.3 0.7 0.2 0.4 0.9 0.3 0.3 0.2 LEPR "CD295, OBR" ENSSSCG00000025188 "one2one with ENSG00000116678" "Leptin receptor precursor " P48357 6 146798979-146895937 "Human disease related genes" "Tissue enhanced" "Detected in many" "bone marrow: 44.4;choroid plexus: 52.3" "Low region specificity" "Detected in all" "Cluster 58 - Immune cells" "Variable (cartilage)" 2.0 31.9 3.5 5.8 54.9 2.3 4.0 0.9 2.6 2.4 4.0 2.6 137.4 2.5 2.7 5.2 2.6 3.4 5.5 3.9 2.5 54.0 4.7 2.7 2.2 1.4 4.1 1.5 3.3 3.8 1.2 0.8 1.1 4.2 1.3 2.3 1.3 0.1 1.5 3.3 3.8 0.3 6.7 2.7 4.2 2.6 3.0 2.1 1.5 2.6 1.6 4.3 3.1 2.5 4.7 4.5 2.6 5.2 10.8 7.2 3.7 1.5 1.7 2.2 1.5 2.1 6.2 2.2 1.0 1.6 3.3 3.2 2.3 1.8 2.0 1.6 2.4 1.3 0.8 1.3 5.6 5.4 6.9 3.2 2.6 2.3 2.2 6.0 13.0 5.2 3.8 4.8 2.0 2.4 5.2 5.7 2.3 3.3 LHX3 ENSSSCG00000034657 "one2one with ENSG00000107187" "LIM/homeobox protein Lhx3 " Q9UBR4 AEMK02000682.1 1473620-1481582 "Human disease related genes" "Tissue enriched" "Detected in some" 17 "pituitary gland: 34.8" "Not detected" "Not detected" "Cluster 20 - Hormonal" "Not variable" 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.3 0.1 0.0 0.1 0.0 0.0 0.0 49.5 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 LHX4 Gsh4 ENSSSCG00000015536 "one2one with ENSG00000121454" "LIM homeobox 4" Q969G2 9 121851232-121896210 "Human disease related genes" "Tissue enriched" "Detected in some" 7 "pineal gland: 62.6" "Not detected" "Not detected" "Cluster 7 - Retinal" "Variable (brain)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 164.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 28.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.8 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 LMNA "CMD1A, HGPS, LGMD1B, LMN1, LMNL1, MADA, PRO1" ENSSSCG00000006496 "one2one with ENSG00000160789" "Prelamin-A/C " P02545 4 93897687-93949802 "Human disease related genes" "Low tissue specificity" "Detected in many" "Low region specificity" "Detected in all" "Cluster 76 - Housekeeping regulation" "Variable (brain)" 114.1 40.0 7.8 114.8 77.0 122.9 161.2 60.3 6.4 232.4 19.5 218.0 32.1 10.9 204.6 150.3 33.3 11.3 46.7 149.8 112.9 228.4 229.4 243.8 10.3 16.8 94.5 117.8 139.4 201.2 41.4 39.0 22.2 15.2 86.5 9.8 94.1 48.5 30.4 53.9 89.9 1.5 295.2 17.9 191.7 23.6 23.3 20.4 9.9 53.9 9.7 15.6 74.0 290.3 77.5 369.4 15.0 60.4 21.0 66.8 206.9 15.5 9.4 27.2 7.1 213.0 5.3 10.8 18.5 32.4 11.3 42.8 149.3 193.2 182.8 11.5 22.6 118.6 64.2 85.8 10.0 24.3 28.8 381.3 10.1 16.2 18.1 17.4 63.6 210.0 43.1 165.0 37.9 161.3 195.0 11.3 9.3 30.7 LPL LIPD ENSSSCG00000040631 "one2one with ENSG00000175445" "Lipoprotein lipase precursor " P06858 14 4104769-4136593 "Human disease related genes" "Tissue enhanced" "Detected in many" "adipose tissue: 134.0;aorta: 89.4;bone marrow: 101.4" "Region enriched" "Detected in many" 4 "basal ganglia: 10.9" "Cluster 81 - Vasculature and connective tissue" "Variable (brain, upper respiratory system)" 406.2 14.0 8.0 179.1 391.4 9.7 9.0 3.5 64.0 15.1 9.1 8.6 13.3 8.5 11.0 7.9 6.1 6.8 69.1 14.4 7.1 18.5 8.8 9.7 6.9 3.0 17.9 528.2 8.0 20.3 32.5 24.8 99.4 6.1 7.7 8.0 12.5 0.7 4.1 6.4 21.4 4.3 53.3 1.7 9.5 13.2 7.6 6.3 6.6 3.4 6.5 16.2 5.8 43.6 24.2 9.7 8.3 4.5 29.3 7.0 90.8 5.8 6.6 3.8 53.9 18.7 16.4 7.8 3.0 3.8 20.2 85.6 16.3 25.8 18.6 6.8 5.3 2.9 1.5 287.6 6.4 18.2 7.2 17.9 7.5 11.8 7.0 16.8 9.8 23.9 7.4 24.9 11.0 6.2 249.9 6.7 33.7 18.4 MC2R ACTHR ENSSSCG00000039227 "one2one with ENSG00000185231" "Adrenocorticotropic hormone receptor " Q01718 6 96265764-96266657 "Human disease related genes" "Tissue enriched" "Detected in some" 18 "adrenal gland: 59.6" "Not detected" "Not detected" "Cluster 20 - Hormonal" "Not variable" 0.7 76.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.8 0.0 0.1 0.3 0.1 0.3 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 3.2 0.0 0.0 1.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 1.6 0.2 0.1 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 6.3 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 MC3R MC3 ENSSSCG00000007491 "one2one with ENSG00000124089" "Melanocortin receptor 3 " P41968 17 56868525-56869605 "Human disease related genes" "Group enriched" "Detected in some" 6 "brain: 6.7;pituitary gland: 19.7" "Group enriched" "Detected in many" 5 "basal ganglia: 6.7;hypothalamus: 4.4;thalamus: 4.3" "Cluster 8 - Neurohormonal" "Variable (brain)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.7 0.0 0.0 0.2 0.0 0.8 0.0 0.0 17.5 0.0 0.6 0.0 0.0 0.1 0.0 2.3 0.0 0.0 0.0 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.9 0.0 0.0 0.2 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.2 0.0 MC4R ENSSSCG00000004904 "one2one with ENSG00000166603" "Melanocortin receptor 4 " P32245 1 160772013-160774124 "Human disease related genes" "Group enriched" "Detected in some" 7 "brain: 17.5;epididymis: 7.4;heart: 8.0" "Low region specificity" "Detected in many" "Cluster 1 - Brain neurotransmission" "Variable (brain, heart)" 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.9 0.0 18.1 0.3 0.0 1.3 0.0 0.1 0.0 1.0 1.2 1.1 0.0 0.0 0.0 0.2 3.9 3.4 0.0 0.0 0.0 0.0 2.0 2.0 0.0 5.8 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 1.0 0.5 0.0 1.7 0.3 0.0 0.0 0.0 0.0 4.4 0.0 0.2 0.0 0.0 1.6 2.2 0.0 0.5 0.0 0.3 1.0 0.0 0.3 4.4 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 2.8 3.7 0.6 0.0 1.7 0.3 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 2.3 0.1 MEN1 ENSSSCG00000013019 "one2one with ENSG00000133895" "Menin 1" O00255 2 7357951-7365069 "Human disease related genes" "Low tissue specificity" "Detected in all" "Low region specificity" "Detected in all" "Cluster 66 - Housekeeping mRNA" "Not variable" 20.7 14.9 15.2 5.3 10.7 14.0 17.6 17.5 15.5 16.2 25.4 18.5 18.6 16.2 16.3 16.0 12.8 17.6 15.6 24.9 14.7 18.1 8.9 26.6 15.5 26.0 17.4 13.2 28.8 17.8 5.7 4.3 4.2 18.3 9.2 15.2 10.9 3.6 12.6 22.1 15.5 5.3 11.3 6.7 21.6 20.6 14.9 14.8 14.1 10.6 14.4 18.8 21.1 14.4 12.8 14.9 17.9 6.2 22.5 18.8 10.1 15.9 15.7 20.8 10.1 15.8 27.6 15.6 10.0 27.2 17.3 5.8 11.0 9.0 10.8 16.9 12.0 10.1 13.3 8.7 19.4 15.5 17.9 11.2 15.7 13.5 15.7 36.2 28.2 10.0 21.7 18.9 11.6 18.9 24.9 20.5 14.8 13.0 MRAP2 "bA51G5.2, C6orf117" ENSSSCG00000026943 "one2one with ENSG00000135324" "Melanocortin 2 receptor accessory protein 2" Q96G30 1 53256257-53318106 "Human disease related genes" "Tissue enhanced" "Detected in many" "cervix: 61.1;endometrium: 22.3;male glands: 25.1" "Low region specificity" "Detected in many" "Cluster 10 - Housekeeping transcription" "Variable (brain, male glands)" 1.7 4.9 6.2 3.9 0.7 1.0 2.1 35.7 5.8 1.4 2.6 140.9 1.8 3.8 1.5 3.5 1.3 3.7 14.0 7.5 1.2 1.9 1.1 58.0 3.5 0.7 2.0 0.5 3.6 2.0 0.8 1.2 0.6 16.2 0.7 4.3 0.8 0.7 0.8 1.9 3.4 0.1 1.8 0.5 2.3 1.2 11.4 4.9 2.9 1.0 2.1 26.0 1.7 1.3 2.0 2.0 14.3 0.7 10.7 39.2 1.0 11.6 3.3 7.1 4.6 1.5 4.7 3.4 0.6 7.7 12.0 0.7 2.0 0.6 1.6 3.1 1.9 0.6 0.2 0.4 5.8 6.5 5.9 1.4 3.2 0.8 9.2 3.9 19.3 1.1 1.3 4.4 3.2 19.9 1.9 5.2 6.4 7.3 MTNR1B ENSSSCG00000014939 "one2one with ENSG00000134640" "Melatonin receptor 1B" P49286 9 25545560-25557652 "Human disease related genes" "Group enriched" "Detected in some" 5 "bone marrow: 2.1;brain: 4.6;cartilage: 2.0;endometrium: 1.9;mouth: 5.1" "Group enriched" "Detected in some" 5 "midbrain: 2.9;pons and medulla: 4.0" "Cluster 4 - Brain development" "Not variable" 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.5 0.1 1.0 0.0 0.0 0.0 0.0 0.7 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.8 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.3 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.3 0.2 0.0 0.1 0.0 0.1 0.0 0.1 1.2 0.0 0.0 0.0 0.0 0.0 0.1 0.1 1.2 na "CELIAC1, HLA-DQA" ENSSSCG00000001456 "one2many with ENSG00000196735" "SLA class II histocompatibility antigen, DQ haplotype D alpha chain precursor " P01909 7 24951495-24995637 "Human disease related genes" "Tissue enhanced" "Detected in many" "lymphoid tissue: 163.6" "Low region specificity" "Detected in all" "Cluster 77 - Housekeeping defense" "Variable (brain, cartilage, lymphoid tissue)" 341.4 69.2 12.7 123.4 274.8 112.0 641.4 117.5 16.6 636.3 14.4 73.1 195.5 16.6 644.5 71.9 44.5 22.0 267.1 113.1 260.5 534.2 164.4 118.8 22.5 42.6 191.7 103.6 105.9 365.5 73.4 77.1 41.7 49.8 212.2 14.2 330.7 1.6 94.5 360.2 176.7 0.1 195.0 49.9 896.4 1112.7 83.8 50.3 12.1 331.2 10.8 65.0 599.2 167.7 459.3 140.5 52.7 41.8 255.3 109.5 142.6 51.8 12.5 83.0 14.7 567.7 5.3 14.8 31.3 38.4 30.8 64.7 60.0 107.1 213.8 13.4 393.7 92.9 111.9 118.2 29.2 107.3 77.8 199.9 21.5 24.6 50.7 389.4 182.7 109.2 1205.8 372.0 54.9 147.3 321.1 27.9 17.7 139.0 na "D15S9, MGC88288, RNF63, ZFP127, ZNF127" ENSSSCG00000004836 "one2one with ENSG00000179455" Q13064 1 142499097-142500982 "Human disease related genes" "Tissue enhanced" "Detected in many" "brain: 13.1;lens: 11.9" "Low region specificity" "Detected in all" "Cluster 3 - Brain cellular structure" "Variable (brain)" 0.5 0.6 2.9 0.2 0.3 0.6 0.4 1.0 3.1 0.5 5.6 0.9 2.1 3.3 0.3 0.3 10.8 3.8 5.6 0.6 0.5 0.4 0.2 0.7 2.5 0.1 1.0 0.5 0.8 0.5 0.1 0.0 0.2 2.5 0.1 2.8 0.3 0.0 0.4 0.9 0.3 2.1 0.4 0.5 0.3 0.2 4.9 4.6 2.6 0.2 2.4 5.1 0.3 0.2 0.2 0.8 3.6 0.1 2.3 0.9 0.1 3.0 2.3 0.3 3.1 0.3 5.7 3.0 0.3 0.0 3.3 0.2 0.2 0.1 0.5 3.3 0.1 0.3 0.0 0.6 3.1 4.6 4.2 0.3 2.6 2.9 4.1 0.4 0.4 0.4 0.2 0.3 0.0 0.4 2.0 3.2 2.8 5.8 na "HSD3B, HSDB3, SDR11E1, SDR11E2" ENSSSCG00000006719 "one2many with ENSG00000203857,ENSG00000203859" "3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase 3-beta-hydroxy-Delta(5)-steroid dehydrogenase Steroid Delta-isomerase" "P14060, P26439" 4 101563728-101573906 "Human disease related genes" "Group enriched" "Detected in some" 13 "adrenal gland: 375.8;ovary: 293.2" "Not detected" "Not detected" "Cluster 20 - Hormonal" "Variable (male glands, upper respiratory system)" 6.7 3827.3 2.0 0.2 0.1 50.2 0.5 0.6 1.9 0.9 0.8 0.6 0.4 1.9 0.7 0.7 0.6 1.9 0.5 38.7 0.6 1.4 1.6 1.0 1.7 36.1 3.2 0.4 1.3 2.4 0.3 0.4 0.1 0.6 0.1 2.1 0.2 0.0 0.6 0.3 4.3 0.2 0.4 32.2 0.3 0.8 0.5 0.6 1.8 3.6 1.1 0.7 0.6 2.3 3733.3 0.1 0.4 0.1 0.8 0.4 0.1 0.4 1.8 12.7 1.2 0.4 1.6 1.7 147.3 28.0 1.0 0.0 2.3 0.1 0.1 1.6 0.3 0.1 0.1 8.8 1.9 0.4 0.4 0.7 1.9 8.1 0.5 0.6 1.7 2.5 1.4 0.4 0.8 0.1 0.7 2.1 1.3 0.5 na "hsyn16, SYN16" ENSSSCG00000007516 "one2many with ENSG00000124222,ENSG00000254995" "Syntaxin-16 " O14662 17 58839997-58891249 "Human disease related genes" "Low tissue specificity" "Detected in all" "Low region specificity" "Detected in all" "Cluster 2 - Brain neurotransmission" "Not variable" 25.7 29.4 49.1 7.1 15.2 19.1 28.0 20.2 45.4 24.3 64.4 28.9 29.7 68.2 25.3 35.0 40.2 53.8 40.3 22.5 26.3 25.3 12.3 26.6 62.4 15.1 33.1 18.6 30.8 20.6 11.4 9.5 10.7 60.1 15.7 61.5 17.1 4.9 16.5 31.8 21.6 11.5 24.4 11.4 27.2 27.8 47.2 54.1 68.8 16.8 69.1 46.9 23.7 21.9 14.4 18.3 60.0 8.5 23.3 35.7 11.3 54.1 65.8 34.4 38.2 25.6 41.4 64.0 12.3 18.1 52.3 16.8 14.7 13.8 23.1 77.5 23.7 17.9 21.0 12.8 52.3 49.1 57.4 17.3 64.1 18.4 61.2 58.1 31.5 17.2 33.6 26.0 21.8 23.0 38.5 54.2 47.8 28.9 na "HHG, LCGR, LGR2, LHR, ULG5" ENSSSCG00000008421 "one2many with ENSG00000138039" "Sus scrofa lutropin-choriogonadotropic hormone receptor-like (LOC100623180), mRNA." P22888 3 91964415-92021398 "Human disease related genes" "Group enriched" "Detected in many" 4 "ovary: 28.1;testis: 49.6" "Low region specificity" "Detected in some" "Cluster 9 - Testis spermatogenesis" "Variable (adipose tissue)" 0.8 0.8 2.1 0.2 0.5 0.2 0.5 0.3 0.9 0.6 1.5 16.9 14.1 1.5 0.6 1.8 0.3 1.0 1.3 2.1 0.3 2.5 0.3 7.2 1.8 0.1 0.3 0.8 2.1 1.6 1.2 1.1 0.5 1.7 0.2 1.2 0.5 0.1 0.7 2.1 0.2 1.3 0.5 0.1 0.5 0.4 1.1 0.9 1.1 0.1 1.6 1.2 0.5 0.7 43.0 0.8 1.7 0.1 12.1 1.0 0.6 0.7 1.5 0.4 0.4 0.8 11.6 1.1 0.1 1.1 1.7 0.3 0.7 0.0 5.9 1.6 0.8 0.3 0.2 2.2 1.3 0.7 1.2 0.4 2.1 93.6 1.1 0.8 0.8 0.6 0.5 0.4 0.3 2.2 4.6 1.2 1.2 1.7 na "AQP7L, AQP9, AQPap" ENSSSCG00000010992 "one2many with ENSG00000165269,ENSG00000259916" "Aquaporin-7 " O14520 10 33098676-33116154 "Human disease related genes" "Tissue enhanced" "Detected in many" "adipose tissue: 52.4;aorta: 24.8;bone marrow: 25.6;testis: 54.4" "Low region specificity" "Detected in some" "Cluster 81 - Vasculature and connective tissue" "Variable (male glands)" 52.2 3.9 2.8 20.8 41.2 7.0 4.2 1.5 2.3 4.5 4.6 3.2 7.6 3.1 3.6 8.8 3.2 2.3 1.8 3.7 4.1 4.7 5.2 3.0 2.6 2.6 6.5 86.2 4.6 5.6 5.8 4.6 11.7 2.3 8.7 3.0 3.6 0.4 22.5 9.0 5.3 1.1 6.5 3.0 3.7 2.2 1.6 1.7 2.1 3.1 2.2 4.8 3.7 6.4 2.9 3.1 2.5 1.3 4.7 2.6 10.4 1.3 2.4 3.2 1.6 4.7 10.8 2.9 2.1 2.5 2.5 10.2 4.6 3.2 3.0 2.2 2.9 2.5 1.1 56.3 2.6 1.8 2.0 3.7 2.8 167.4 1.7 4.9 5.3 4.2 3.1 5.6 4.6 2.8 5.4 2.7 2.1 1.6 na "ADMLX, KAL, KAL1, KALIG-1, WFDC19" ENSSSCG00000012101 "one2many with ENSG00000011201" P23352 X 5165698-5363002 "Human disease related genes" "Tissue enriched" "Detected in some" 12 "cartilage: 69.6" "Low region specificity" "Detected in many" "Cluster 4 - Brain development" "Variable (brain, cartilage)" 0.2 1.0 4.6 0.5 0.1 0.8 6.8 0.6 5.6 0.0 0.8 0.2 0.1 4.3 0.1 0.9 0.6 2.1 3.6 0.4 0.0 0.2 2.3 0.3 5.8 1.7 0.3 0.5 0.2 0.7 0.0 0.3 0.1 2.4 0.0 6.4 0.0 21.4 0.1 2.4 0.3 0.3 2.2 0.0 7.7 0.0 4.1 2.3 4.9 0.2 3.5 2.4 0.1 1.3 0.1 2.4 4.3 0.5 0.6 0.7 2.0 2.6 4.9 0.7 3.4 0.0 5.4 5.1 0.0 0.0 2.9 0.7 2.8 2.8 0.8 4.8 0.0 0.1 0.0 0.3 5.0 2.0 2.5 8.1 5.5 0.1 2.9 0.7 0.3 1.1 0.2 0.5 0.3 0.7 2.1 2.9 4.0 4.2 na ENSSSCG00000014097 "one2many with ENSG00000113231,ENSG00000284762" O95263 2 86045531-86323794 "Human disease related genes" "Tissue enhanced" "Detected in many" "brain: 29.5;thyroid gland: 26.6" "Low region specificity" "Detected in all" "Cluster 2 - Brain neurotransmission" "Variable (adipose tissue, brain, lymphoid tissue, male glands)" 27.9 5.5 17.0 3.0 1.5 5.8 8.6 18.4 58.3 31.2 4.8 1.9 4.3 43.4 38.3 5.7 6.6 16.7 7.4 9.9 10.9 5.4 1.9 6.8 50.4 2.4 11.7 2.4 22.2 14.5 0.4 0.3 0.4 26.3 4.2 37.3 5.0 0.0 6.5 27.5 14.8 0.1 2.4 2.6 7.5 3.3 9.8 14.7 35.7 7.6 52.3 30.7 11.8 2.6 8.1 9.1 17.0 1.5 46.2 24.6 3.5 15.8 37.4 19.4 48.7 34.2 44.8 34.6 10.3 2.4 42.6 0.3 3.3 1.1 1.6 57.0 18.5 4.0 12.2 6.5 27.4 9.4 20.1 1.4 50.5 1.6 17.1 2.5 67.8 2.7 4.9 14.3 11.1 17.6 4.8 20.1 56.9 5.7 na "HER3, LCCS2" ENSSSCG00000020725 "one2one with ENSG00000065361" P21860 5 21474625-21496279 "Human disease related genes" "Tissue enhanced" "Detected in many" "liver: 49.6;vagus nerve: 57.8" "Low region specificity" "Detected in all" "Cluster 65 - Epithelium" "Variable (brain, cartilage, kidney)" 9.6 1.7 12.0 2.0 1.3 51.3 10.5 60.8 8.6 93.9 5.2 2.9 1.0 7.8 82.5 36.0 110.8 19.3 44.8 43.3 57.3 8.6 10.1 13.9 6.0 18.9 33.9 1.6 25.9 32.1 3.2 2.1 1.8 23.7 33.0 8.3 30.3 0.1 26.5 7.2 30.9 0.1 17.8 63.7 13.4 2.4 38.2 33.4 7.8 18.7 9.2 23.8 14.4 23.0 0.6 8.2 30.8 7.2 1.8 1.9 8.4 24.3 6.1 30.0 24.7 52.2 3.5 12.5 20.7 36.1 21.6 0.4 21.0 22.5 9.1 10.4 1.4 59.5 44.6 2.4 8.7 42.9 31.4 2.4 6.3 2.0 30.3 2.8 5.6 15.4 5.7 30.9 25.2 10.6 210.9 13.9 28.7 31.2 na "hClC-Ka, hClC-Kb" ENSSSCG00000026345 "one2many with ENSG00000184908,ENSG00000186510" "P51800, P51801" 6 75179589-75193090 "Human disease related genes" "Tissue enriched" "Detected in some" 6 "kidney: 62.1" "Not detected" "Not detected" "Cluster 39 - Kidney transport" "Variable (upper respiratory system)" 0.1 0.1 0.2 0.1 0.1 0.1 1.5 3.0 0.1 1.3 0.1 0.6 3.0 0.3 0.6 0.4 0.1 0.0 0.2 0.4 0.3 0.3 0.0 0.5 0.2 1.1 0.6 0.0 0.8 0.8 1.3 0.6 0.5 0.2 1.4 0.2 0.6 0.0 59.1 152.3 2.0 0.0 0.3 0.0 0.4 0.2 0.2 0.1 0.2 8.3 0.1 1.0 5.2 4.1 1.0 0.7 0.2 0.0 0.5 1.7 0.1 0.2 0.3 0.5 0.0 0.4 0.4 0.2 10.1 0.0 0.2 0.1 0.3 0.1 0.8 0.2 0.5 0.2 0.1 0.0 0.3 0.2 0.4 0.3 0.2 0.0 0.1 0.5 1.5 0.4 0.3 2.3 1.4 0.2 0.2 0.2 0.2 0.1 na "CD221, IGFIR, IGFR, JTK13, MGC18216" ENSSSCG00000030560 "one2one with ENSG00000140443" "Insulin-like growth factor 1 receptor precursor " P08069 1 137387825-137692307 "Human disease related genes" "Low tissue specificity" "Detected in all" "Low region specificity" "Detected in all" "Cluster 71 - Housekeeping regulation" "Not variable" 37.3 44.8 22.5 13.8 22.0 49.3 42.0 36.0 20.7 24.0 39.2 77.7 31.7 25.4 27.9 129.4 20.1 21.8 23.1 73.7 59.3 52.5 39.0 66.2 23.7 50.8 58.9 24.4 89.6 23.7 27.5 21.1 24.5 19.0 17.6 25.0 26.7 12.5 104.0 94.5 82.7 15.1 52.1 9.1 42.5 18.9 20.8 20.7 19.8 44.4 21.3 38.8 43.7 52.8 60.3 49.9 20.4 12.7 31.3 46.2 29.8 17.4 23.2 79.5 13.8 29.9 57.1 22.6 22.8 40.2 20.6 14.2 37.4 26.8 88.6 24.8 21.1 22.5 32.5 20.4 25.5 23.6 24.3 33.6 24.6 11.5 20.2 28.9 76.2 38.2 20.1 72.7 57.8 62.1 49.4 23.9 19.6 20.5 na "CGB4, hLHB, LSH-B" ENSSSCG00000031086 "one2many with ENSG00000104826" "Lutropin subunit beta " P01229 6 54263576-54268682 "Human disease related genes" "Tissue enriched" "Detected in some" 36 "pituitary gland: 196.2" "Region enhanced" "Detected in single" "hypothalamus: 2.3" "Cluster 20 - Hormonal" "Variable (brain)" 0.3 0.8 1.1 0.1 0.1 2.5 30.2 1.6 1.5 0.3 0.9 0.8 1.3 0.5 0.4 2.1 0.7 1.2 0.7 1.5 0.3 0.4 0.4 5.9 0.5 2.0 2.2 0.1 32.2 0.5 0.3 0.2 0.1 16.1 0.3 0.5 0.2 0.0 0.4 0.9 12.3 0.0 2.6 0.2 17.6 0.4 1.1 0.7 0.4 6.8 0.4 0.9 10.5 2.1 0.5 2.1 5.3 0.2 1.1 1570.2 0.2 1.5 0.5 1.8 0.5 0.3 2.0 0.5 0.8 1.0 1.8 4.5 1.4 1.0 0.5 0.4 0.4 0.6 0.6 0.1 0.7 0.8 3.0 0.8 0.5 8.9 0.8 1.7 3.6 2.7 0.7 21.5 1.9 3.0 0.5 1.7 0.8 0.5 na "ALDOS, CPN1, CPN2, CYP11B, CYP11B, CYP11BL, FHI, P-450C18, P450aldo, P450C11" ENSSSCG00000031563 "one2many with ENSG00000160882,ENSG00000179142" "P15538, P19099" 4 1367921-1373136 "Human disease related genes" "Tissue enriched" "Detected in some" 10 "adrenal gland: 437.0" "Not detected" "Not detected" "Cluster 20 - Hormonal" "Not variable" 0.0 4117.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.8 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.1 0.2 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 1.4 0.2 0.7 0.0 0.0 0.0 0.0 0.0 0.0 638.8 0.0 0.0 0.0 0.2 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 na Cav3.2 ENSSSCG00000034266 "one2one with ENSG00000196557" O95180 3 40633235-40694815 "Human disease related genes" "Tissue enhanced" "Detected in many" "ductus deferens: 33.3;smooth muscle: 41.2" "Low region specificity" "Detected in many" "Cluster 74 - Extracellular matrix" "Variable (brain, lymphoid tissue)" 5.2 27.7 8.1 4.5 1.3 7.3 6.6 0.4 9.5 7.4 0.5 53.1 0.8 5.4 8.8 0.3 0.5 3.5 3.7 64.3 5.4 6.6 8.6 42.6 5.0 11.2 0.9 4.7 19.7 29.2 5.6 6.3 2.2 5.3 7.9 6.3 13.2 2.3 0.8 1.2 1.0 0.0 6.0 0.5 6.8 1.2 4.3 3.6 5.6 2.2 4.0 14.4 1.7 5.0 10.9 32.4 4.9 5.7 1.1 14.6 12.0 3.1 5.4 2.6 6.0 9.8 9.5 5.4 0.2 4.3 6.4 1.4 5.6 5.1 72.9 5.1 4.3 3.9 3.3 3.3 5.4 4.3 3.2 7.5 6.1 9.5 2.9 0.1 1.0 4.5 0.6 5.0 2.7 41.5 12.3 4.6 7.8 5.7 na "PTPT, TC-PTP, TCELLPTP, TCPTP" ENSSSCG00000035094 "one2one with ENSG00000175354" P17706 2 52540084-52543659 "Human disease related genes" "Tissue enriched" "Detected in single" 10 "testis: 2.3" "Not detected" "Not detected" "Cluster 11 - Testis uncharacterized" "Not variable" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 na "ADMLX, KAL, KAL1, KALIG-1, WFDC19" ENSSSCG00000038192 "one2many with ENSG00000011201" P23352 Y 3806899-3963055 "Human disease related genes" "Tissue enriched" "Detected in many" 4 "cartilage: 99.1" "Low region specificity" "Detected in all" "Cluster 1 - Brain neurotransmission" "Variable (brain, cartilage)" 1.9 5.1 57.7 1.3 1.2 3.9 20.3 4.8 59.8 1.4 16.6 2.8 4.0 55.2 1.9 10.9 11.1 27.8 35.7 4.8 2.1 4.3 5.7 4.4 65.1 4.3 4.5 1.5 7.7 2.8 1.8 2.1 1.6 26.2 0.9 72.9 1.4 48.8 2.4 12.2 3.6 3.6 10.4 0.9 29.5 1.2 39.1 27.9 54.6 2.4 43.6 34.5 2.3 5.6 1.6 6.1 43.8 1.6 8.6 8.2 3.3 29.1 57.4 5.1 34.3 2.1 66.6 55.9 1.3 2.5 34.1 3.8 5.6 4.0 5.7 53.2 1.7 1.7 1.2 1.5 59.7 25.6 26.0 15.0 67.7 2.5 31.3 5.3 29.4 6.8 3.0 5.2 4.2 3.3 9.5 36.5 50.5 37.0 na ENSSSCG00000038903 "one2many with ENSG00000128655,ENSG00000284741" Q9HCR9 15 83366724-83758253 "Human disease related genes" "Tissue enhanced" "Detected in many" "ductus deferens: 7.0;gallbladder: 7.5;large intestine: 6.4;testis: 10.6" "Low region specificity" "Detected in many" "Cluster 6 - Brain uncharacterized" "Not variable" 0.1 0.6 1.4 0.0 0.0 0.0 0.1 0.0 0.4 0.5 0.2 0.3 0.4 0.5 3.4 0.1 1.3 2.0 3.5 3.6 0.3 0.2 0.1 0.4 0.4 0.4 0.2 0.0 1.1 3.9 0.2 0.1 0.0 1.5 0.1 0.5 0.2 0.0 0.4 0.4 0.3 0.0 0.1 0.3 0.1 0.0 1.4 0.8 0.3 0.1 0.3 2.3 1.4 0.2 0.7 0.0 1.4 0.0 0.8 0.7 0.0 0.9 0.3 0.0 0.2 2.2 1.6 0.4 0.0 0.1 2.1 0.0 0.2 0.1 0.3 0.3 0.0 0.1 0.0 0.0 2.0 0.9 0.7 0.0 0.6 6.3 0.7 0.1 0.1 0.0 0.1 0.4 0.0 1.9 0.4 3.1 0.8 0.8 na ENSSSCG00000039037 "one2one with ENSG00000165588" P32243 14 66071117-66071950 "Human disease related genes" "Tissue enhanced" "Detected in many" "testis: 10.3" "Not detected" "Not detected" "Cluster 16 - Aorta uncharacterized" "Not variable" 0.2 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.2 0.0 0.1 0.4 0.2 0.2 0.0 0.1 0.0 0.1 0.1 0.1 0.1 0.2 0.1 0.2 0.2 0.5 0.3 0.0 0.6 0.2 0.2 0.1 0.1 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.1 0.1 0.3 0.1 0.1 0.1 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.3 0.2 0.0 0.0 0.2 0.0 0.1 0.0 0.5 0.2 0.0 0.1 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.1 3.7 0.0 0.1 0.1 0.0 0.1 0.2 0.0 0.2 0.5 0.2 0.1 0.0 na "BWCR, BWS, KIP2, P57" ENSSSCG00000040461 "one2one with ENSG00000129757" P49918 2 2018910-2022082 "Human disease related genes" "Low tissue specificity" "Detected in many" "Low region specificity" "Detected in many" "Cluster 74 - Extracellular matrix" "Variable (brain, cartilage)" 10.3 12.4 4.1 7.8 19.7 6.6 6.2 2.3 2.0 1.6 1.2 49.9 1.3 2.5 1.2 15.5 23.4 3.5 18.6 14.1 1.6 23.7 4.6 15.5 2.3 2.4 4.0 9.8 8.0 12.2 5.1 5.5 4.2 6.0 0.7 2.9 1.3 5.7 32.5 22.2 5.0 7.3 10.5 2.2 7.6 1.2 11.7 10.6 2.2 4.6 1.7 3.8 6.7 8.0 18.7 5.1 6.0 8.9 2.3 3.6 9.8 6.1 2.1 2.3 2.9 1.9 1.6 3.0 1.2 7.7 4.2 6.1 1.8 0.8 3.4 1.8 1.0 1.4 1.2 4.5 3.9 8.4 7.0 13.5 2.1 16.7 7.0 0.6 3.3 9.0 1.6 6.9 5.5 7.0 28.2 3.8 4.2 18.6 na "B27, C21orf61, FALP" ENSSSCG00000040843 "one2one with ENSG00000170262" Q8TCY5 13 195950999-195975657 "Human disease related genes" "Group enriched" "Detected in some" 12 "adrenal gland: 175.2;ovary: 43.9" "Not detected" "Not detected" "Cluster 20 - Hormonal" "Not variable" 1.9 677.0 2.2 0.6 1.0 2.1 6.3 0.7 1.8 1.4 3.3 2.6 2.2 2.1 1.6 4.0 2.5 1.8 2.0 6.8 1.4 3.4 1.7 2.1 1.8 1.6 2.2 1.3 2.5 1.7 0.9 0.7 0.7 1.8 0.7 2.2 0.9 0.1 0.8 2.2 1.6 1.0 3.0 0.8 5.9 1.7 1.4 1.6 1.6 1.2 1.5 3.2 1.6 2.0 212.2 4.9 1.7 0.4 2.9 2.8 1.3 1.3 1.5 1.2 1.2 1.3 4.4 1.9 1.6 1.3 2.0 0.8 1.8 1.9 1.8 1.9 3.1 0.6 0.5 1.0 1.9 1.8 1.8 2.2 1.9 52.9 1.5 4.4 3.4 2.0 1.9 2.0 1.3 1.8 2.9 2.0 1.9 1.6 NAA25 "C12orf30, FLJ13089" ENSSSCG00000009887 "one2one with ENSG00000111300" "N(alpha)-acetyltransferase 25, NatB auxiliary subunit" Q14CX7 14 39579503-39682469 "Human disease related genes" "Low tissue specificity" "Detected in all" "Low region specificity" "Detected in all" "Cluster 66 - Housekeeping mRNA" "Not variable" 9.8 11.8 13.7 3.3 7.3 13.3 14.9 14.4 11.9 15.8 23.2 16.2 18.1 17.0 16.5 25.3 14.5 14.6 13.0 14.2 17.0 15.6 8.7 17.4 14.4 11.1 17.7 6.2 18.1 13.3 5.8 4.6 6.3 15.1 7.2 13.7 10.1 1.6 9.2 18.5 14.7 4.5 22.9 9.0 15.9 18.0 13.5 13.5 13.4 11.4 14.5 21.1 13.8 20.7 18.0 9.9 15.7 2.8 23.9 17.5 6.9 14.5 12.4 12.7 10.6 14.7 30.1 14.8 7.3 21.4 14.9 12.0 14.1 13.3 13.3 16.5 11.8 7.8 3.7 6.2 14.4 14.0 15.9 7.9 15.3 17.7 13.9 28.6 14.1 19.7 22.5 15.1 9.5 17.1 18.1 14.9 13.2 11.4 NEUROD1 "BETA2, BHF-1, bHLHa3, MODY6, NeuroD" ENSSSCG00000016011 "one2one with ENSG00000162992" "Neuronal differentiation 1" Q13562 15 87175766-87179819 "Human disease related genes" "Group enriched" "Detected in some" 66 "brain: 90.5;pineal gland: 64.9;retina: 43.6" "Region enriched" "Detected in many" 20 "cerebellum: 90.5" "Cluster 2 - Brain neurotransmission" "Variable (brain)" 0.0 0.0 6.2 0.0 0.0 0.0 0.0 0.0 0.0 0.7 447.6 0.0 0.1 3.1 0.7 0.0 0.5 15.4 0.1 0.0 2.4 1.3 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 1.1 2.6 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 4.1 2.1 0.0 3.1 0.6 0.2 0.0 0.0 0.0 0.4 0.0 318.5 4.8 0.0 1.3 3.6 0.0 0.0 0.7 253.8 1.8 0.0 0.0 0.2 0.0 0.0 0.0 0.0 3.2 0.0 1.1 0.0 0.0 5.8 0.3 8.5 0.0 6.6 0.1 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.0 0.2 0.1 NKX2-1 "BCH, NKX2A, TITF1, TTF-1, TTF1" ENSSSCG00000001945 "one2one with ENSG00000136352" "Homeobox protein Nkx-2.1 isoform 2 " P43699 7 63487807-63491575 "Human disease related genes" "Group enriched" "Detected in some" 11 "lung: 22.4;thyroid gland: 86.5" "Group enriched" "Detected in some" 13 "basal ganglia: 2.1;hypothalamus: 5.1" "Cluster 38 - Lung and thyroid development" "Variable (brain)" 0.0 0.0 0.7 0.0 0.0 0.0 42.5 0.0 2.8 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.1 0.0 0.3 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 66.1 0.0 0.0 0.2 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 15.1 0.0 0.0 0.2 0.0 2.1 0.0 0.0 0.3 0.0 0.0 6.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.4 0.0 0.0 0.1 0.3 0.0 0.0 265.8 0.0 0.0 3.1 0.0 0.0 0.0 0.2 3.4 0.0 NKX2-5 "CSX, CSX1, NKX2.5, NKX2E, NKX4-1" ENSSSCG00000036285 "one2one with ENSG00000183072" "NK2 homeobox 5" P52952 16 51086022-51092937 "Human disease related genes" "Tissue enriched" "Detected in some" 5 "heart: 34.6" "Not detected" "Not detected" "Cluster 49 - Heart contraction" "Variable (lymphoid tissue)" 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.4 8.7 15.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 6.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 NNT ENSSSCG00000016877 "one2one with ENSG00000112992" "Nicotinamide nucleotide transhydrogenase" Q13423 16 28157280-28249540 "Human disease related genes" "Tissue enhanced" "Detected in all" "skeletal muscle: 81.1" "Low region specificity" "Detected in all" "Cluster 19 - Housekeeping mitochondrial" "Variable (male glands)" 17.6 26.6 38.6 6.0 12.4 10.8 19.7 22.6 46.2 49.8 50.6 25.2 132.6 47.7 50.4 31.5 27.3 46.2 32.5 19.9 28.0 33.6 13.9 31.8 45.1 7.5 22.0 11.4 18.2 36.4 21.0 14.0 53.5 38.6 13.6 42.4 22.1 2.9 25.5 52.4 19.4 6.5 63.6 34.0 27.5 28.2 40.7 41.7 46.7 23.5 47.9 57.7 27.9 58.2 32.3 15.6 41.8 4.4 78.6 31.4 8.6 38.4 41.7 16.3 43.6 36.2 42.2 44.9 16.5 9.3 43.5 101.3 11.2 7.4 30.9 54.5 15.7 15.0 10.4 10.7 46.8 40.1 52.4 28.4 49.3 26.3 45.9 55.0 30.2 39.0 37.3 22.1 49.1 17.6 17.0 43.8 43.7 33.8 NOTCH2 ENSSSCG00000006709 "one2one with ENSG00000134250" "Notch 2" Q04721 4 100951359-101150179 "Human disease related genes" "Low tissue specificity" "Detected in all" "Low region specificity" "Detected in all" "Cluster 76 - Housekeeping regulation" "Variable (brain, male glands)" 73.6 16.0 15.5 16.4 38.7 35.1 42.7 21.6 13.0 20.7 8.2 173.7 136.2 11.3 26.3 52.3 10.7 12.6 29.8 100.3 27.7 102.4 37.5 127.7 13.0 35.0 42.4 48.7 82.0 44.2 16.2 15.5 8.2 20.7 13.3 12.3 22.7 14.1 24.8 54.3 26.0 1.6 46.4 14.0 56.3 50.5 19.6 16.2 9.8 32.8 7.5 18.8 44.7 54.6 84.1 62.7 22.3 18.5 27.6 24.6 26.4 14.7 9.7 50.7 7.5 34.0 12.7 11.0 14.8 87.8 14.8 10.6 25.2 20.0 54.2 9.0 44.1 13.1 12.5 33.9 18.6 23.1 38.5 63.0 11.9 22.2 15.5 28.7 63.3 36.9 49.0 48.4 23.5 42.5 73.1 16.1 11.9 20.9 NR0B1 "AHC, AHCH, DAX1, DSS" ENSSSCG00000012199 "one2one with ENSG00000169297" "Nuclear receptor subfamily 0 group B member 1 " P51843 X 26117838-26122995 "Human disease related genes" "Group enriched" "Detected in some" 5 "adrenal gland: 13.9;male glands: 12.3;pituitary gland: 4.0;testis: 3.6" "Low region specificity" "Detected in some" "Cluster 20 - Hormonal" "Variable (male glands)" 0.0 5.7 0.1 0.0 0.0 0.0 0.1 0.1 0.9 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 3.1 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 2.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.0 NR0B2 SHP ENSSSCG00000003565 "one2one with ENSG00000131910" "Nuclear receptor subfamily 0 group B member 2" Q15466 6 84225238-84229681 "Human disease related genes" "Tissue enhanced" "Detected in many" "adrenal gland: 18.5;liver: 25.7" "Low region specificity" "Detected in many" "Cluster 51 - Liver and kidney" "Not variable" 1.1 11.9 1.6 0.5 0.9 1.6 2.0 0.6 1.2 2.3 2.3 2.0 2.0 1.6 2.2 2.1 1.6 0.8 0.9 1.6 4.1 1.9 1.6 2.5 1.2 1.2 2.3 1.1 3.3 1.9 1.2 0.8 1.0 1.1 1.2 1.5 1.8 0.0 1.5 2.7 2.0 0.1 2.3 9.6 2.2 1.6 0.8 0.9 1.0 1.2 1.0 2.1 1.7 1.9 1.1 1.7 1.4 0.4 1.8 1.7 0.8 0.7 1.3 1.4 0.9 1.7 3.2 1.5 0.7 1.8 1.1 1.5 1.2 1.2 1.5 1.2 1.4 1.5 0.6 0.9 1.2 1.0 0.8 1.0 1.4 6.2 0.8 4.2 5.3 1.8 2.0 2.0 1.3 1.8 2.2 1.2 1.1 0.9 NR3C1 "GR, GRL" ENSSSCG00000014401 "one2one with ENSG00000113580" "Glucocorticoid receptor " P04150 2 144822078-144956456 "Human disease related genes" "Low tissue specificity" "Detected in all" "Low region specificity" "Detected in all" "Cluster 75 - Housekeeping" "Not variable" 43.1 7.9 23.8 16.0 36.7 28.3 38.9 37.8 18.1 19.4 39.4 19.6 26.7 21.0 22.3 41.1 45.3 22.1 37.4 22.8 30.8 71.7 24.9 19.1 19.5 5.8 35.8 36.1 22.9 31.7 17.6 15.3 14.5 35.8 14.9 18.6 23.9 6.2 15.5 25.6 21.0 3.8 41.1 19.7 46.1 35.6 32.1 29.9 17.7 21.4 18.0 26.4 28.7 29.2 19.8 36.2 34.9 12.8 27.9 33.6 21.5 26.6 17.0 20.2 19.3 23.4 21.9 19.6 15.2 14.5 29.1 36.7 16.8 12.1 35.4 22.2 36.0 22.7 14.1 23.3 21.7 31.6 32.4 38.5 19.9 15.4 29.9 57.8 42.4 27.8 41.5 29.8 17.2 24.8 42.2 21.8 22.9 32.7 NR5A1 "AD4BP, ELP, FTZ1, FTZF1, hSF-1, SF-1" ENSSSCG00000005588 "one2one with ENSG00000136931" "Steroidogenic factor 1 " Q13285 1 265284493-265308179 "Human disease related genes" "Tissue enriched" "Detected in some" 6 "adrenal gland: 82.9" "Not detected" "Not detected" "Cluster 20 - Hormonal" "Variable (lymphoid tissue)" 0.0 150.6 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.9 0.0 0.0 0.0 0.0 32.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 36.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 NSMF NELF ENSSSCG00000037880 "one2one with ENSG00000165802" "NMDA receptor synaptonuclear signaling and neuronal migration factor" Q6X4W1 AEMK02000682.1 478380-515011 "Human disease related genes" "Tissue enhanced" "Detected in all" "brain: 71.4" "Low region specificity" "Detected in all" "Cluster 5 - Intracellular signalling" "Not variable" 44.2 33.6 218.3 15.8 20.6 68.7 41.1 26.0 153.6 47.8 35.9 43.0 89.5 236.1 48.9 79.1 66.2 333.1 41.7 42.0 38.7 44.1 41.7 40.9 188.1 41.1 54.8 38.8 45.1 42.6 19.0 15.4 9.4 70.6 39.2 239.5 37.1 15.2 47.5 27.5 70.5 16.1 56.7 44.6 27.6 22.9 48.2 73.0 253.2 33.9 170.9 91.0 43.0 54.2 44.2 53.7 61.5 18.6 31.7 49.3 32.0 55.6 238.2 55.2 104.2 49.7 36.6 235.0 45.7 37.5 102.4 13.9 40.3 65.3 26.5 210.0 21.9 59.1 85.7 28.1 192.6 52.1 85.2 42.8 220.3 29.6 83.8 25.3 41.0 50.2 29.3 64.8 34.3 77.0 80.8 357.1 106.0 54.4 P14ARF "ARF, CDK4I, CDKN2, CMM2, INK4, INK4a, MLM, MTS1, p14, p14ARF, p16, p16INK4a, p19, p19Arf" ENSSSCG00000005134 "one2one with ENSG00000147889" "P14ARF protein " "P42771, Q8N726" 1 200774496-200798854 "Human disease related genes" "Tissue enriched" "Detected in many" 8 "testis: 66.5" "Low region specificity" "Detected in some" "Cluster 15 - Testis uncharacterized" "Variable (brain, mouth)" 0.8 11.9 0.8 0.4 1.6 0.4 6.0 3.5 0.8 2.1 2.5 0.4 2.9 1.2 1.8 0.5 0.8 3.9 2.7 0.3 1.4 0.6 0.5 1.3 0.6 1.2 3.2 0.4 0.1 3.9 0.2 0.3 0.2 1.8 1.3 0.7 1.8 0.2 0.1 1.2 2.6 0.0 0.9 0.1 11.3 6.0 1.9 1.5 0.9 5.8 1.0 3.8 7.0 6.1 5.0 0.3 1.2 0.8 1.2 5.0 0.4 1.1 0.7 3.9 0.8 1.7 0.1 0.9 1.6 1.0 1.7 0.1 0.6 0.4 0.0 0.5 1.8 1.5 0.9 0.0 0.6 1.9 3.2 1.2 0.8 146.6 1.6 2.6 0.6 1.4 6.8 3.8 0.7 1.2 1.7 3.5 1.0 5.4 PAX4 MODY9 ENSSSCG00000016591 "one2one with ENSG00000106331" "Paired box 4" O43316 18 20674562-20680287 "Human disease related genes" "Tissue enhanced" "Detected in some" "large intestine: 2.5;ovary: 2.4;small intestine: 7.2;stomach: 1.7" "Not detected" "Not detected" "Cluster 63 - Small intestine" "Not variable" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PCSK1 "NEC1, PC1, PC3, SPC3" ENSSSCG00000014169 "one2one with ENSG00000175426" "Neuroendocrine convertase 1 precursor " P29120 2 103004790-103050839 "Human disease related genes" "Group enriched" "Detected in some" 5 "brain: 28.5;pineal gland: 47.8;pituitary gland: 42.7" "Low region specificity" "Detected in many" "Cluster 1 - Brain neurotransmission" "Variable (brain)" 0.2 10.7 8.6 0.0 0.2 0.8 0.1 0.0 12.3 2.2 0.9 0.3 0.3 64.8 2.4 0.7 7.3 47.2 5.2 0.1 4.4 0.3 0.2 0.3 54.7 0.0 0.5 0.3 0.7 0.2 0.1 0.2 0.2 62.6 1.3 42.2 2.6 0.1 1.2 1.3 1.3 0.1 0.4 0.9 0.2 0.0 9.2 12.4 58.7 0.2 67.3 23.1 0.4 0.3 18.2 0.5 13.9 0.0 181.9 159.8 0.0 15.7 58.3 0.3 12.7 3.5 8.8 66.9 0.3 0.4 41.5 0.1 0.4 0.1 1.3 72.6 0.0 1.6 0.0 0.3 19.5 31.7 14.1 0.1 51.0 0.4 9.7 0.1 4.0 0.0 0.1 1.3 0.2 0.1 0.4 23.6 18.0 1.6 PDX1 "IDX-1, IPF1, MODY4, PDX-1, STF-1" ENSSSCG00000035817 "one2one with ENSG00000139515" "Pancreatic and duodenal homeobox 1" P52945 11 5303609-5310843 "Human disease related genes" "Tissue enhanced" "Detected in some" "gallbladder: 6.9;small intestine: 29.1;stomach: 9.1" "Not detected" "Not detected" "Cluster 63 - Small intestine" 0.2 0.2 0.3 0.1 0.2 0.3 0.4 0.1 0.2 0.4 0.6 0.4 0.6 0.3 0.3 0.4 0.4 0.2 0.2 0.3 27.3 0.4 0.3 0.4 0.2 0.1 0.5 0.2 0.4 6.8 0.1 0.1 0.1 0.2 7.0 0.3 6.9 0.0 0.2 0.4 0.4 0.0 0.4 0.2 0.3 0.3 0.1 0.2 0.2 0.2 0.2 0.5 0.3 0.3 0.1 0.1 0.3 0.1 0.4 0.3 0.2 0.1 0.2 0.2 0.1 0.3 0.7 0.3 0.2 0.2 0.2 0.2 0.2 0.1 0.3 0.2 0.3 4.9 0.2 0.1 0.2 0.2 0.1 0.2 0.2 0.3 0.2 0.7 0.5 0.2 0.4 0.3 0.2 0.2 0.6 0.2 0.2 0.2 PIK3CA PI3K ENSSSCG00000030413 "one2one with ENSG00000121879" "Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha" P42336 13 117179941-117278498 "Human disease related genes" "Low tissue specificity" "Detected in all" "Low region specificity" "Detected in all" "Cluster 10 - Housekeeping transcription" "Not variable" 15.2 11.2 25.6 5.9 11.0 9.2 21.8 23.6 19.7 16.5 57.7 32.1 30.2 30.8 18.5 22.4 28.0 30.2 26.8 16.1 16.5 33.8 8.7 25.1 27.7 6.0 21.7 8.8 24.6 14.8 6.9 5.9 6.4 31.4 7.7 24.2 14.4 3.6 8.9 22.9 12.8 12.4 17.8 6.4 32.1 25.4 29.4 31.3 25.4 12.1 26.9 44.6 19.0 19.0 19.1 13.7 32.6 5.1 54.9 40.6 8.6 32.1 24.1 5.9 19.5 18.9 59.2 27.3 6.4 10.0 29.2 14.1 10.2 8.0 25.9 31.7 13.2 7.0 3.5 7.3 28.8 30.7 36.1 13.2 27.1 20.5 32.4 33.5 26.5 16.6 28.3 20.1 7.6 16.4 23.5 29.6 23.4 26.0 PLAGL1 "LOT1, ZAC" ENSSSCG00000004127 "one2one with ENSG00000118495" "Zinc finger protein PLAGL1 " Q9UM63 1 21303994-21371067 "Human disease related genes" "Low tissue specificity" "Detected in all" "Low region specificity" "Detected in all" "Cluster 75 - Housekeeping" "Not variable" 17.6 10.0 8.9 5.6 10.8 8.9 23.8 8.1 8.9 14.5 8.8 27.5 3.2 6.2 13.7 15.5 5.5 6.0 6.4 17.8 11.6 24.7 15.9 27.0 6.7 6.7 23.0 14.2 13.6 14.5 16.8 12.0 9.0 10.6 10.5 6.5 9.9 7.1 14.9 25.6 16.2 1.8 21.9 0.9 27.8 15.2 5.7 6.3 4.2 10.8 5.0 11.1 15.7 14.7 20.9 15.9 9.4 3.9 5.0 73.4 10.6 5.4 5.1 9.2 5.3 13.8 11.2 5.7 6.0 10.8 12.0 4.0 7.6 11.5 17.2 5.0 13.4 6.1 8.7 14.2 8.1 6.5 6.3 16.4 6.5 3.2 5.7 39.7 51.2 18.1 17.9 21.1 6.5 11.0 19.1 6.0 9.0 5.1 POMC "ACTH, CLIP, LPH, MSH, NPP, POC" ENSSSCG00000021155 "one2one with ENSG00000115138" "Pro-opiomelanocortin precursor " P01189 3 113661004-113670624 "Human disease related genes" "Tissue enriched" "Detected in some" 213 "pituitary gland: 930.7" "Region enriched" "Detected in single" 4 "hypothalamus: 2.3" "Cluster 20 - Hormonal" "Variable (brain)" 5.0 5.2 7.1 1.7 2.8 5.3 4.4 3.5 6.0 3.6 12.7 6.8 6.7 7.4 4.0 6.5 8.6 6.6 7.1 5.5 3.6 6.9 4.4 6.6 6.6 3.3 5.2 4.3 9.2 3.2 2.4 1.6 2.1 77.9 2.0 7.4 2.3 1.1 3.0 6.5 4.5 1.0 6.8 1.7 4.7 4.1 13.7 11.4 6.2 3.8 6.4 23.6 4.8 3.6 4.0 95.9 10.0 1.9 11.0 35355.5 2.9 8.9 6.4 3.5 5.1 3.4 16.8 7.5 1.7 2.4 7.4 2.3 3.6 2.6 3.7 6.2 3.2 2.3 1.8 3.8 6.9 9.1 84.6 3.6 6.9 24.7 7.4 8.1 6.9 3.6 4.5 7.1 3.0 3.9 9.6 12.9 6.7 7.6 PON1 "ESA, PON" ENSSSCG00000015332 "one2one with ENSG00000005421" "Serum paraoxonase/arylesterase 1 precursor " P27169 9 74926048-74974827 "Human disease related genes" "Group enriched" "Detected in some" 5 "kidney: 41.1;liver: 90.4" "Low region specificity" "Detected in some" "Cluster 12 - Metabolic" "Variable (kidney)" 1.2 0.9 2.6 0.5 25.0 0.3 2.8 0.4 3.2 0.8 2.4 2.3 2.6 3.2 0.9 1.3 2.9 2.6 1.6 0.6 0.3 9.8 0.4 1.1 2.9 0.2 0.6 1.1 2.2 2.8 0.3 0.1 0.3 3.1 0.2 2.5 0.2 0.0 75.7 3.0 8.0 0.2 0.5 112.0 3.0 0.1 1.8 2.1 2.7 14.5 2.6 2.9 27.6 1.4 0.6 0.3 2.6 0.3 1.9 5.0 0.7 2.0 2.5 0.3 3.2 1.3 3.0 3.0 0.7 1.4 4.0 0.3 2.1 0.1 0.5 3.0 0.0 0.2 0.1 2.7 2.9 1.8 1.9 0.2 2.4 2.0 2.1 0.1 2.4 1.0 0.1 16.6 0.7 2.2 1.0 2.6 3.5 1.2 POR "CYPOR, FLJ26468" ENSSSCG00000038320 "one2one with ENSG00000127948" "NADPH--cytochrome P450 reductase " P16435 3 10211187-10281833 "Human disease related genes" "Low tissue specificity" "Detected in all" "Low region specificity" "Detected in all" "Cluster 61 - Enzymes and secretion" "Not variable" 31.6 91.5 20.7 9.3 16.2 29.3 70.6 37.6 18.9 52.7 26.9 29.6 86.2 18.7 48.7 43.1 25.6 25.8 27.9 29.3 30.9 26.6 16.1 35.9 17.9 15.2 21.6 27.5 23.1 56.3 10.7 8.1 17.0 37.4 28.4 17.5 22.7 2.5 31.2 31.2 71.0 3.8 19.1 60.0 81.0 18.8 26.5 25.2 16.5 112.5 15.8 25.7 128.0 34.5 122.6 18.3 30.8 5.5 38.1 68.2 13.8 24.5 17.1 40.1 14.0 32.4 26.1 17.5 21.8 30.1 28.3 20.1 14.0 8.9 15.4 19.8 13.9 17.4 20.1 23.4 24.2 27.1 29.7 22.7 18.6 144.5 25.8 37.8 34.7 16.1 21.6 119.4 25.2 37.7 23.9 29.2 19.8 25.1 POU1F1 "GHF-1, PIT1, POU1F1a" ENSSSCG00000011996 "one2one with ENSG00000064835" "Pituitary-specific positive transcription factor 1 " P28069 13 168510748-168528711 "Human disease related genes" "Tissue enriched" "Detected in many" 26 "pituitary gland: 76.5" "Low region specificity" "Detected in many" "Cluster 44 - Housekeeping" "Not variable" 2.3 2.1 3.6 0.8 1.7 2.2 3.7 0.7 2.8 3.0 6.1 3.9 4.5 3.5 3.1 5.9 3.8 2.5 2.0 3.4 2.8 4.9 2.4 4.2 2.8 1.7 3.4 2.1 4.7 2.5 1.7 1.2 1.1 2.8 1.5 3.5 1.7 0.1 1.7 3.6 2.8 0.4 3.7 1.6 4.2 2.8 2.1 2.0 2.1 2.0 2.3 6.6 2.5 2.6 2.4 4.1 3.1 0.7 4.7 235.2 1.5 1.6 2.7 2.0 2.0 2.6 9.5 3.3 0.9 1.9 3.0 1.5 2.0 1.5 3.4 2.5 3.1 1.1 0.8 1.3 2.9 2.5 2.2 1.8 3.2 3.5 1.8 8.7 4.7 2.9 3.8 3.2 1.9 2.3 4.3 3.1 2.7 1.8 PPARG "NR1C3, PPARG1, PPARG2, PPARgamma" ENSSSCG00000011579 "one2one with ENSG00000132170" "Peroxisome proliferator-activated receptor gamma " P37231 13 68301566-68433963 "Human disease related genes" "Tissue enhanced" "Detected in many" "adipose tissue: 52.9;aorta: 32.5;bone marrow: 41.6;large intestine: 29.5;lymphoid tissue: 33.8" "Not detected" "Not detected" "Cluster 75 - Housekeeping" "Variable (cartilage, kidney, lymphoid tissue)" 88.7 1.8 0.6 31.4 77.7 15.0 13.1 0.4 0.3 89.6 0.2 27.0 0.8 0.2 81.1 0.2 0.5 0.5 1.2 1.9 10.8 17.8 6.9 3.4 0.3 0.2 5.4 95.3 0.6 4.5 2.0 2.1 2.3 0.9 2.0 0.3 3.4 0.0 1.7 13.6 5.7 2.1 5.9 0.2 16.9 2.0 0.5 0.4 0.3 2.3 0.2 1.0 3.1 4.6 4.9 13.5 0.8 2.8 1.3 0.4 22.8 0.6 0.2 0.3 0.2 37.3 0.2 0.4 1.0 0.5 1.0 3.3 9.2 2.0 3.3 0.2 70.6 32.9 24.6 78.2 0.5 0.6 0.4 8.5 0.3 1.4 0.5 1.7 6.3 3.2 1.6 9.4 1.1 63.1 5.5 0.4 0.3 0.5 PPARGC1B "PERC, PGC1B" ENSSSCG00000014437 "one2one with ENSG00000155846" "PPARG coactivator 1 beta" Q86YN6 2 150823368-150919366 "Human disease related genes" "Tissue enhanced" "Detected in many" "stomach: 41.6" "Low region specificity" "Detected in all" "Cluster 66 - Housekeeping mRNA" "Variable (brain, lymphoid tissue)" 7.4 2.1 6.9 3.1 4.7 6.0 7.8 0.8 7.8 24.5 13.4 22.3 5.6 7.3 21.2 7.6 1.7 6.2 2.6 10.1 12.6 6.3 3.7 9.5 7.2 2.7 3.3 14.9 7.7 9.8 6.5 4.8 9.7 4.5 15.6 8.1 14.7 0.3 7.4 5.7 10.2 0.6 12.8 1.5 6.6 3.1 3.4 5.0 6.9 7.0 6.7 9.9 8.2 10.6 3.3 7.0 3.7 2.9 3.9 1.9 9.2 4.6 6.5 2.0 5.4 18.3 24.1 6.7 4.5 1.9 5.7 8.9 8.0 6.0 17.1 8.7 10.2 15.1 30.9 4.9 5.5 3.4 5.8 6.2 7.9 0.7 6.0 4.6 5.1 8.6 3.9 10.8 2.7 10.9 5.1 7.8 6.3 2.1 PRKACA PKACa ENSSSCG00000013771 "one2one with ENSG00000072062" "Protein kinase cAMP-activated catalytic subunit alpha" P17612 2 65074503-65095920 "Human disease related genes" "Low tissue specificity" "Detected in all" "Low region specificity" "Detected in all" "Cluster 19 - Housekeeping mitochondrial" "Not variable" 86.6 116.3 94.4 30.5 49.1 36.0 62.6 55.7 97.2 66.8 145.4 115.8 101.7 111.5 71.4 74.5 79.9 131.7 103.4 107.6 55.8 73.9 38.1 116.6 102.9 35.4 53.0 61.8 91.7 88.0 48.1 35.8 66.2 140.2 32.9 94.2 50.1 9.5 32.9 71.0 45.7 60.7 63.2 27.5 79.8 57.1 106.7 118.1 100.1 44.1 105.3 97.4 68.8 79.7 81.4 74.9 121.0 21.9 116.5 222.3 40.7 125.5 107.2 45.1 73.3 67.5 117.5 102.3 21.9 46.2 124.4 100.4 40.3 20.7 168.9 127.8 43.7 33.9 23.2 44.9 118.1 122.4 127.4 67.1 106.7 171.9 124.9 77.6 85.3 50.8 64.9 89.7 54.2 97.7 74.0 133.6 103.0 108.2 PRKAR1A "CNC1, PRKAR1, TSE1" ENSSSCG00000017259 "one2one with ENSG00000108946" "CAMP-dependent protein kinase type I-alpha regulatory subunit " P10644 12 11661872-11681435 "Human disease related genes" "Low tissue specificity" "Detected in all" "Low region specificity" "Detected in all" "Cluster 10 - Housekeeping transcription" "Not variable" 71.0 126.6 165.6 33.2 56.8 40.4 67.7 83.8 157.6 68.4 253.7 317.1 154.9 198.1 73.4 124.0 203.9 191.7 190.9 112.6 56.4 129.8 43.4 180.7 183.9 32.9 62.9 46.7 114.8 106.6 39.8 36.6 39.5 235.3 27.4 150.8 56.3 28.3 44.1 125.1 57.4 29.7 71.8 28.1 92.1 67.7 182.2 196.7 169.7 64.4 168.3 221.3 92.4 63.0 141.0 81.5 198.8 21.8 178.7 396.9 46.9 199.8 169.5 29.4 132.8 75.2 127.0 178.5 22.8 48.9 234.7 33.7 41.9 24.7 144.2 203.2 35.3 26.8 12.1 34.5 199.8 194.3 194.5 56.8 178.6 124.5 196.2 94.6 132.4 59.7 84.3 108.4 33.3 70.3 115.7 198.7 177.9 171.1 PRKCQ ENSSSCG00000011131 "one2one with ENSG00000065675" "Protein kinase C theta" Q04759 10 64442406-64600342 "Human disease related genes" "Tissue enhanced" "Detected in all" "choroid plexus: 30.7;lymphoid tissue: 36.3;skeletal muscle: 40.3;testis: 32.0" "Low region specificity" "Detected in all" "Cluster 22 - Housekeeping transcription" "Variable (brain)" 4.2 3.5 11.1 1.9 5.2 3.5 14.1 1.6 9.8 12.4 13.2 5.8 76.1 10.6 12.7 8.3 42.1 14.0 13.9 4.7 8.8 7.1 3.2 7.0 8.5 4.7 7.5 2.5 8.3 5.3 2.3 1.7 1.5 14.3 8.4 9.8 7.4 2.6 5.5 31.0 5.7 0.7 10.8 3.5 14.5 29.3 16.0 11.9 8.5 5.2 8.8 13.6 8.2 10.1 3.6 3.2 16.9 1.3 7.9 6.0 2.3 10.4 7.9 3.8 14.1 9.9 22.6 14.7 1.8 2.7 14.2 34.6 3.5 3.5 4.5 9.3 15.3 4.8 10.8 2.0 13.7 17.4 13.3 11.0 8.4 71.4 12.2 95.2 7.9 13.7 35.0 7.2 8.6 3.6 7.1 13.0 15.8 10.3 PRLR ENSSSCG00000016830 "one2one with ENSG00000113494" "Prolactin receptor precursor " P16471 16 20618696-20655926 "Human disease related genes" "Tissue enhanced" "Detected in many" "adrenal gland: 51.2;choroid plexus: 87.3" "Low region specificity" "Detected in many" "Cluster 70 - Housekeeping" "Variable (brain, heart, kidney, male glands, mesothelial tissue)" 3.1 114.3 1.4 1.0 1.4 31.4 0.5 5.5 0.7 0.4 0.6 66.1 333.9 0.4 0.7 7.4 0.7 0.4 1.7 8.5 17.3 0.1 2.2 12.7 0.4 3.4 1.9 2.8 22.6 0.4 0.5 1.9 11.5 9.3 8.4 0.3 6.6 0.0 23.0 5.5 3.0 0.1 5.5 4.1 0.5 0.3 7.8 1.7 0.2 3.2 0.3 0.7 2.3 1.7 1.7 0.8 5.2 1.6 16.6 21.1 0.3 2.0 0.2 21.6 0.3 0.8 0.9 0.3 1.5 1.4 4.1 0.0 7.5 20.4 2.4 0.1 0.7 1.4 2.4 0.8 0.6 2.7 19.8 0.7 0.4 0.3 3.9 0.6 4.7 1.8 0.7 2.0 11.4 1.5 0.1 0.7 0.7 0.7 PROK2 "BV8, KAL4, MIT1, PK2" ENSSSCG00000026200 "one2one with ENSG00000163421" "Prokineticin 2" Q9HC23 13 53170525-53184664 "Human disease related genes" "Tissue enhanced" "Detected in some" "brain: 6.9;heart: 11.5;testis: 35.8" "Region enhanced" "Detected in many" "olfactory region: 6.9" "Cluster 9 - Testis spermatogenesis" "Variable (brain, heart)" 0.1 0.1 0.7 0.0 2.3 0.2 0.2 0.1 0.2 0.3 0.2 0.5 0.0 0.3 0.3 0.1 0.2 0.0 0.7 0.1 0.3 3.5 0.1 0.7 0.3 0.2 0.0 0.0 0.0 0.0 5.3 0.0 0.1 1.4 0.2 0.0 0.8 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.6 0.1 0.3 1.2 0.1 0.0 0.4 11.4 1.1 0.0 0.9 0.1 0.0 0.0 0.3 0.0 0.0 0.7 0.1 0.2 0.6 0.4 0.4 0.0 0.0 0.2 1.7 0.0 0.0 0.0 1.2 0.6 0.0 0.0 0.0 0.0 0.5 1.3 1.7 0.4 0.1 45.1 1.6 0.4 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.1 2.4 0.3 PROKR2 "dJ680N4.3, GPR73b, GPR73L1, GPRg2, KAL3, PKR2" ENSSSCG00000037063 "one2one with ENSG00000101292" "Prokineticin receptor 2" Q8NFJ6 17 14242504-14257379 "Human disease related genes" "Low tissue specificity" "Detected in all" "Low region specificity" "Detected in all" "Cluster 44 - Housekeeping" "Variable (brain)" 13.9 20.6 40.9 4.8 9.7 15.7 23.2 5.9 30.5 20.1 64.1 24.1 47.6 42.6 22.1 36.2 34.3 28.1 18.2 21.5 21.7 32.7 13.4 27.6 33.7 14.7 29.7 10.3 35.0 17.6 11.3 8.6 9.1 27.4 11.6 39.7 11.6 2.0 16.1 27.4 21.6 4.1 24.2 13.7 28.0 16.2 18.0 18.8 26.5 14.7 27.6 89.5 18.8 18.9 15.1 14.2 29.8 4.9 48.3 41.5 8.1 14.9 30.9 16.4 19.2 18.3 102.6 38.1 8.3 15.4 29.7 12.7 13.8 12.4 18.9 26.9 16.3 9.4 4.3 8.6 35.5 21.4 16.7 11.7 35.7 31.5 16.9 53.8 36.5 18.4 24.5 23.3 16.2 13.6 34.6 32.8 27.7 15.5 PROP1 ENSSSCG00000029569 "one2one with ENSG00000175325" "Homeobox protein prophet of Pit-1 " O75360 2 79627603-79631270 "Human disease related genes" "Tissue enriched" "Detected in all" 4 "pituitary gland: 38.2" "Low region specificity" "Detected in all" "Cluster 44 - Housekeeping" "Not variable" 2.7 3.0 6.0 1.0 2.0 4.0 4.8 1.9 5.1 3.4 9.1 4.3 7.0 4.6 3.3 8.2 7.9 4.1 3.8 3.8 4.0 6.3 3.5 5.0 4.0 6.1 5.6 2.3 5.1 3.9 2.2 1.5 1.4 4.6 1.9 5.4 2.0 0.3 2.9 5.6 4.6 0.6 5.0 2.3 3.8 2.8 3.5 3.1 4.0 2.8 3.2 7.8 3.8 3.9 3.2 3.0 5.2 1.3 4.4 55.5 2.5 2.8 3.9 4.3 3.5 3.1 8.6 4.8 1.9 2.4 5.1 2.7 3.0 2.0 3.6 4.0 3.1 1.9 1.1 2.0 4.7 4.3 3.1 2.5 4.8 3.4 2.9 7.3 5.9 3.9 3.7 4.8 3.3 2.3 7.6 4.7 4.6 3.8 PTF1A "bHLHa29, PTF1-p48" ENSSSCG00000030662 "one2one with ENSG00000168267" "Pancreas specific transcription factor, 1a" Q7RTS3 10 51818388-51819761 "Human disease related genes" "Tissue enhanced" "Detected in some" "fallopian tube: 2.4;kidney: 1.7;retina: 2.2" "Low region specificity" "Detected in some" "Cluster 23 - Cilium structure" "Not variable" 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 PTH PTH1 ENSSSCG00000013394 "one2one with ENSG00000152266" "Parathyroid hormone " P01270 2 45757398-45760415 "Human disease related genes" "Tissue enhanced" "Detected in many" "brain: 5.7" "Low region specificity" "Detected in all" "Cluster 3 - Brain cellular structure" "Not variable" 0.1 0.1 2.5 0.0 0.0 0.3 0.1 0.1 0.5 0.6 0.8 0.3 0.3 1.8 0.7 0.1 1.1 1.1 2.1 1.6 0.5 0.3 0.1 0.4 1.1 0.9 0.2 0.1 0.5 0.1 0.1 0.1 0.0 1.0 0.2 0.9 0.1 0.0 0.2 1.0 0.1 0.0 0.1 0.0 0.1 0.1 1.9 1.3 0.5 0.1 1.8 1.4 0.2 0.1 0.1 0.0 1.1 0.0 0.6 0.4 0.1 0.7 0.5 0.1 0.5 0.4 1.4 1.7 0.0 0.6 1.9 0.0 0.0 0.1 0.3 1.0 0.2 0.1 0.1 0.0 2.3 1.4 1.2 0.0 2.1 2.0 1.4 0.2 0.7 0.4 0.1 0.0 0.0 0.8 1.2 1.0 1.3 1.5 PTPN22 "Lyp, Lyp1, Lyp2, PTPN8" ENSSSCG00000006764 "one2one with ENSG00000134242" "Protein tyrosine phosphatase, non-receptor type 22" Q9Y2R2 4 106687787-106758094 "Human disease related genes" "Tissue enhanced" "Detected in many" "large intestine: 13.3;lymphoid tissue: 29.9" "Not detected" "Not detected" "Cluster 78 - Lymphoid T cells" "Variable (cartilage)" 2.5 0.3 0.0 0.9 9.1 0.5 9.9 0.1 0.0 17.3 0.0 0.2 0.6 0.1 15.9 0.4 0.2 0.0 0.5 0.6 6.6 13.9 0.1 0.6 0.1 3.9 2.6 0.7 0.6 2.5 0.1 0.2 0.1 0.2 7.3 0.1 8.4 0.8 0.7 2.4 4.4 0.7 1.3 1.3 11.7 19.9 0.3 0.1 0.0 5.1 0.0 0.4 5.8 1.4 1.4 0.3 0.2 0.1 1.1 0.4 0.5 0.1 0.0 0.1 0.0 8.9 0.3 0.0 1.3 0.3 0.2 0.2 0.2 0.4 0.7 0.0 26.9 3.0 3.4 0.4 0.1 0.3 0.3 0.3 0.0 0.7 0.1 12.7 0.7 0.6 24.2 6.1 0.2 0.8 0.2 0.0 0.1 0.3 RASD1 "AGS1, DEXRAS1" ENSSSCG00000034044 "one2one with ENSG00000108551" "Ras related dexamethasone induced 1" Q9Y272 12 60922422-60926283 "Human disease related genes" "Tissue enhanced" "Detected in all" "epididymis: 28.4;male glands: 47.4" "Low region specificity" "Detected in all" "Cluster 29 - Male tissue bacterial defense" "Variable (male glands)" 3.8 8.0 5.3 3.5 3.7 9.0 3.7 3.0 3.8 2.0 5.7 4.2 3.7 4.9 1.9 5.8 3.8 5.0 5.1 20.3 3.2 9.9 3.2 3.9 5.0 30.0 3.4 2.3 7.0 11.7 2.4 1.6 1.3 6.6 1.4 4.6 1.9 1.0 4.3 9.1 3.7 0.7 4.4 3.4 3.3 2.2 4.0 4.7 4.4 2.3 4.7 5.3 2.7 4.5 15.8 8.1 4.7 2.2 3.6 42.1 8.9 5.0 4.6 3.1 3.0 2.0 5.9 4.7 1.4 44.8 5.6 1.4 3.3 5.4 3.3 5.6 2.3 2.7 3.2 1.8 4.6 4.3 6.1 4.8 5.0 3.9 5.6 5.9 3.7 2.2 2.5 5.2 3.1 4.2 10.7 5.6 4.2 3.3 RFX6 "dJ955L16.1, MGC33442, RFXDC1" ENSSSCG00000039333 "one2one with ENSG00000185002" "Regulatory factor X6" Q8HWS3 1 44765129-44825811 "Human disease related genes" "Tissue enhanced" "Detected in some" "endometrium: 16.0;esophagus: 11.9;salivary gland: 43.3" "Not detected" "Not detected" "Cluster 65 - Epithelium" 0.2 6.0 0.0 0.0 0.1 0.5 1.7 0.0 0.1 0.6 0.1 0.3 0.1 0.5 0.9 1.6 0.5 0.1 0.2 0.5 6.7 0.1 0.7 28.7 0.1 0.2 17.4 0.1 0.7 1.0 0.5 0.6 0.5 0.1 2.6 0.2 3.0 0.1 4.9 4.2 0.9 0.0 0.4 0.2 1.3 0.2 0.3 0.3 0.3 1.1 0.1 0.5 0.1 2.1 0.3 0.3 0.1 0.0 0.1 11.2 0.0 0.2 0.2 0.1 0.1 2.8 0.4 0.4 25.1 0.0 0.1 1.9 0.0 0.1 0.2 0.2 0.0 5.0 0.5 0.1 0.1 0.4 0.2 0.2 0.1 0.2 0.2 0.0 1.3 0.4 0.5 0.2 0.6 0.3 0.1 0.1 0.1 0.3 SDC3 "N-syndecan, SYND3" ENSSSCG00000003592 "one2one with ENSG00000162512" "Syndecan 3" O75056 6 87495043-87535845 "Human disease related genes" "Tissue enhanced" "Detected in all" "brain: 64.9;cartilage: 42.7" "Low region specificity" "Detected in all" "Cluster 4 - Brain development" "Variable (brain, cartilage, lymphoid tissue, male glands)" 40.0 20.6 117.1 5.9 24.7 9.2 70.6 2.3 93.4 12.3 49.6 24.5 6.5 121.0 13.8 8.3 61.1 73.7 147.2 32.8 17.0 39.3 20.2 38.2 127.8 51.7 12.2 20.0 24.4 33.8 10.1 15.2 8.8 119.0 11.3 132.7 16.3 24.5 3.8 13.1 12.2 2.0 18.3 26.2 81.3 28.3 157.1 125.8 109.8 13.9 104.2 112.9 16.5 14.1 31.0 21.7 119.7 7.4 53.4 26.9 15.8 128.5 123.6 7.2 76.1 16.1 37.6 111.0 5.9 5.3 101.6 6.5 9.0 7.7 27.6 121.8 58.3 10.2 11.8 10.0 119.6 149.0 123.5 47.1 125.9 7.5 140.4 5.3 10.6 12.1 23.7 18.2 10.9 24.3 146.5 101.4 104.0 232.4 SECISBP2 SBP2 ENSSSCG00000028033 "one2one with ENSG00000187742" "SECIS binding protein 2" Q96T21 14 912015-955974 "Human disease related genes" "Low tissue specificity" "Detected in all" "Low region specificity" "Detected in all" "Cluster 66 - Housekeeping mRNA" "Not variable" 19.6 26.1 19.7 7.6 17.8 26.4 34.2 19.5 16.5 39.2 37.5 31.0 23.4 19.7 38.9 38.1 25.6 19.4 22.8 23.4 38.6 28.7 16.7 30.0 18.3 32.8 31.8 15.2 36.2 23.1 8.6 8.4 6.8 25.7 21.8 18.2 22.7 3.2 21.9 33.4 26.7 13.0 40.1 16.4 29.9 39.3 20.7 21.0 17.0 21.0 18.2 28.2 24.2 29.2 22.7 16.8 23.1 5.6 28.4 29.9 12.2 21.3 16.7 18.0 15.6 35.0 35.2 19.0 15.7 17.3 23.1 9.1 24.9 26.9 19.8 19.6 32.8 21.9 19.6 13.5 19.9 24.2 22.3 16.1 18.3 79.4 20.2 60.9 37.2 33.2 49.7 25.0 13.6 24.5 28.7 18.9 19.2 18.3 SEMA3A "coll-1, Hsema-I, SEMA1, SEMAD, SemD" ENSSSCG00000015398 "one2one with ENSG00000075213" "Semaphorin 3A" Q14563 9 96066121-96385774 "Human disease related genes" "Tissue enriched" "Detected in many" 15 "cartilage: 141.5" "Low region specificity" "Detected in many" "Cluster 12 - Metabolic" "Variable (cartilage, lymphoid tissue)" 1.5 6.4 11.2 0.3 4.1 12.5 1.1 0.1 3.8 2.6 18.3 4.3 3.4 8.1 4.7 17.1 1.6 5.0 2.5 6.2 2.2 7.7 1.9 8.5 8.4 2.2 1.1 2.6 10.0 1.8 0.0 0.2 0.1 5.7 1.9 6.9 4.1 88.1 0.2 0.3 2.5 7.3 6.9 0.2 1.6 6.3 4.7 6.4 5.4 3.6 9.2 26.6 8.0 8.3 36.4 0.8 1.3 0.5 2.2 19.5 1.0 4.4 5.4 0.1 2.5 2.6 44.0 6.7 0.9 0.7 11.2 0.2 2.0 2.1 9.3 10.8 2.1 1.1 0.5 2.6 12.6 2.0 3.1 1.1 10.9 13.0 1.0 0.5 1.6 6.4 3.1 7.4 0.3 7.5 2.3 5.4 15.8 11.7 SERPINA6 CBG ENSSSCG00000002475 "one2one with ENSG00000170099" "Corticosteroid-binding globulin precursor " P08185 7 115535471-115554817 "Human disease related genes" "Tissue enriched" "Detected in some" 29 "liver: 79.4" "Not detected" "Not detected" "Cluster 51 - Liver and kidney" "Variable (male glands)" 0.2 0.1 0.4 0.0 0.0 0.0 0.2 0.2 0.4 0.0 1.3 0.0 0.0 0.4 0.0 0.3 0.3 1.0 0.7 3.8 0.0 0.0 0.0 0.1 0.4 1.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.2 0.0 0.5 0.0 0.0 0.0 0.3 0.1 0.1 0.1 78.4 0.1 0.0 0.3 0.2 0.3 0.1 0.3 0.5 0.2 0.2 0.5 0.0 0.2 0.0 0.9 0.2 0.0 0.2 0.5 0.0 0.3 0.0 0.2 0.4 0.0 3.7 0.4 0.0 0.1 0.0 0.0 0.4 0.3 0.1 0.1 0.1 0.5 0.4 0.4 0.2 0.3 0.7 0.3 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 1.2 0.3 0.7 SH2B3 "IDDM20, LNK" ENSSSCG00000009833 "one2one with ENSG00000111252" "SH2B adaptor protein 3" Q9UQQ2 14 32623281-32664606 "Human disease related genes" "Low tissue specificity" "Detected in all" "Low region specificity" "Detected in all" "Cluster 77 - Housekeeping defense" "Variable (lymphoid tissue)" 25.6 14.9 10.1 14.4 23.2 14.9 26.9 4.5 8.4 13.3 9.0 13.5 9.5 8.4 14.5 10.5 8.3 8.2 8.9 15.8 12.5 28.0 16.9 14.7 8.7 3.8 12.6 25.6 12.7 18.6 9.9 9.7 7.9 11.5 8.7 9.5 11.6 1.7 7.5 20.2 10.7 0.9 23.8 9.6 33.6 38.2 7.5 7.4 7.6 12.0 6.6 9.8 17.0 17.7 30.7 17.2 9.9 7.7 11.3 8.2 25.4 7.3 7.8 7.3 6.8 15.1 7.7 8.2 3.4 3.2 11.0 7.1 10.8 8.4 18.6 7.8 42.3 7.2 10.5 16.7 10.4 9.5 7.9 29.1 9.0 44.9 7.0 13.6 18.6 12.2 31.6 17.4 9.1 12.5 18.8 9.5 9.3 6.8 SIM1 bHLHe14 ENSSSCG00000004357 "one2one with ENSG00000112246" "Single-minded homolog 1 " P81133 1 67217960-67294756 "Human disease related genes" "Tissue enhanced" "Detected in some" "epididymis: 8.6;kidney: 40.7;male glands: 12.0" "Group enriched" "Detected in some" 5 "basal ganglia: 1.8;hypothalamus: 3.1" "Cluster 39 - Kidney transport" "Variable (male glands)" 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 3.0 0.0 0.1 2.1 0.3 0.0 7.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.2 0.0 0.1 0.0 0.0 16.0 61.9 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.1 0.5 0.0 1.4 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.5 2.6 1.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.8 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.2 0.0 0.1 0.0 2.5 0.0 SLA-DQB1 "CELIAC1, HLA-DQB, HLA-DXB, IDDM1" ENSSSCG00000001457 "one2many with ENSG00000179344,ENSG00000232629" "SLA class II histocompatibility antigen, DQ haplotype C beta chain precursor " P05538 7 24939676-24977270 "Human disease related genes" "Tissue enhanced" "Detected in many" "lymphoid tissue: 129.0" "Low region specificity" "Detected in all" "Cluster 77 - Housekeeping defense" "Variable (brain, cartilage, lymphoid tissue)" 238.4 40.6 10.3 89.7 187.2 61.8 387.9 44.7 11.7 310.3 9.9 45.6 120.0 12.2 284.6 38.5 28.1 15.4 161.4 71.6 125.6 321.5 113.4 65.1 15.9 19.8 107.7 83.8 57.2 226.8 60.0 57.4 40.1 30.7 100.6 12.0 174.9 0.9 45.9 213.7 107.2 0.1 110.4 23.3 553.6 657.0 46.9 31.4 10.1 171.6 8.7 102.2 333.7 99.5 174.1 127.9 30.4 35.4 130.5 63.5 127.5 32.6 11.2 42.9 10.1 265.8 5.3 11.8 12.3 19.0 20.9 42.8 40.1 37.9 129.3 11.9 250.1 69.2 89.7 90.5 17.8 65.7 48.9 154.4 14.8 15.4 33.0 148.8 91.0 58.9 591.5 199.8 43.9 87.2 151.4 18.7 13.0 82.2 SLC12A1 NKCC2 ENSSSCG00000004659 "one2one with ENSG00000074803" "Solute carrier family 12 member 1" Q13621 1 123481369-123571586 "Human disease related genes" "Tissue enriched" "Detected in some" 50 "kidney: 142.8" "Low region specificity" "Detected in some" "Cluster 39 - Kidney transport" "Variable (brain)" 1.0 1.7 3.7 0.4 0.3 0.8 0.7 0.1 0.6 0.2 6.6 1.0 3.0 3.2 0.6 2.5 1.3 2.8 1.8 0.8 0.5 1.1 0.8 1.2 3.0 1.1 0.9 0.8 2.7 0.7 0.2 0.2 0.2 4.3 0.2 3.0 0.4 0.1 134.0 697.4 0.6 0.1 1.5 0.3 0.9 0.5 2.6 2.4 2.4 0.8 2.8 1.5 1.4 0.8 0.4 0.7 7.1 0.3 0.9 17.5 0.1 3.5 2.1 0.4 0.6 0.5 1.4 3.4 0.3 0.1 2.4 0.1 0.5 0.7 0.5 2.5 0.7 0.3 0.2 0.7 2.4 2.3 1.3 0.4 2.9 1.2 2.3 0.9 0.4 1.3 0.9 0.8 0.4 0.5 1.1 2.8 1.3 0.7 SLC12A3 NCCT ENSSSCG00000032643 "one2one with ENSG00000070915" "Solute carrier family 12 member 3" P55017 6 18844799-18885179 "Human disease related genes" "Tissue enriched" "Detected in single" 167 "kidney: 111.7" "Not detected" "Not detected" "Cluster 39 - Kidney transport" "Variable (kidney)" 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.8 0.1 0.6 0.2 0.0 1.6 0.1 0.1 0.6 1.2 0.9 0.0 0.1 0.0 0.0 0.1 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.1 2.1 0.2 0.0 230.7 1.0 0.0 0.1 0.0 0.0 0.0 0.1 1.1 1.1 1.5 0.0 1.4 1.0 0.2 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 1.0 1.7 0.0 0.9 0.1 1.6 1.6 0.0 0.0 1.0 0.0 0.0 0.0 0.1 1.3 0.1 0.0 0.1 0.0 1.2 0.9 0.7 0.0 1.9 0.0 1.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.8 1.3 0.9 SLC16A2 "AHDS, DXS128, MCT7, MCT8, MRX22, XPCT" ENSSSCG00000029458 "one2one with ENSG00000147100" "Solute carrier family 16 member 2" P36021 X 59747966-59898716 "Human disease related genes" "Tissue enhanced" "Detected in all" "adrenal gland: 42.6;choroid plexus: 40.3" "Low region specificity" "Detected in all" "Cluster 3 - Brain cellular structure" "Variable (kidney)" 11.7 64.8 38.2 3.7 6.8 12.2 13.0 7.1 28.5 9.1 27.7 13.8 105.4 34.6 9.7 23.6 36.6 48.4 45.2 9.6 9.3 20.6 11.3 16.7 33.5 4.1 14.4 10.0 28.6 10.1 5.8 4.3 3.9 26.9 4.8 35.3 7.2 1.5 35.3 9.7 13.7 1.4 19.7 3.3 15.9 10.0 38.0 31.2 28.6 19.3 23.4 46.7 17.4 12.9 8.6 12.0 28.3 4.8 56.4 37.3 7.2 22.3 33.4 8.1 19.5 8.5 46.3 33.0 4.8 6.0 28.5 5.4 7.4 6.5 14.7 29.2 6.7 4.7 3.5 5.9 43.6 30.8 27.9 8.4 37.4 7.3 24.9 18.1 58.5 13.3 13.6 20.5 8.5 10.5 17.2 50.1 26.7 49.1 SLC19A2 "THTR1, TRMA" ENSSSCG00000006290 "one2one with ENSG00000117479" "Thiamine transporter 1 " O60779 4 81510128-81536464 "Human disease related genes" "Low tissue specificity" "Detected in all" "Low region specificity" "Detected in all" "Cluster 49 - Heart contraction" "Not variable" 6.6 4.3 8.6 3.5 3.6 6.8 7.4 6.0 7.7 7.5 13.0 11.3 17.8 8.9 7.4 13.5 6.6 9.2 7.1 10.9 11.0 11.3 10.1 15.3 8.0 10.3 13.3 6.0 9.2 9.3 5.0 3.1 7.6 8.9 3.8 8.0 4.5 2.5 4.9 9.9 7.9 1.2 15.6 3.5 10.6 4.3 7.2 7.4 7.0 5.6 7.7 17.5 5.8 10.9 6.4 7.4 12.3 2.2 13.7 12.7 5.5 6.9 7.2 4.3 5.2 6.8 16.6 8.6 3.1 3.8 8.9 11.9 5.1 4.6 6.2 8.5 3.7 3.6 2.4 5.3 10.0 8.4 8.7 10.2 8.5 4.4 6.9 9.2 14.2 11.8 6.5 8.9 4.5 3.9 9.7 10.0 7.5 6.4 SLC26A4 "DFNB4, PDS" ENSSSCG00000028969 "one2one with ENSG00000091137" "Solute carrier family 26 member 4" O43511 9 107365339-107431717 "Human disease related genes" "Tissue enhanced" "Detected in all" "esophagus: 25.5" "Low region specificity" "Detected in all" "Cluster 44 - Housekeeping" "Not variable" 2.0 2.9 4.4 0.6 1.5 2.9 3.2 1.3 2.6 2.9 5.3 3.4 4.2 6.5 3.1 5.6 4.5 2.7 2.0 3.4 2.6 4.1 3.2 5.6 7.4 3.0 22.6 1.7 5.4 2.5 1.6 1.1 1.0 2.9 1.3 6.5 1.5 0.3 8.7 4.8 3.7 0.6 3.6 1.5 3.4 2.6 2.1 2.0 4.2 3.0 6.1 6.1 2.8 3.5 2.0 2.4 3.2 0.7 3.8 5.0 1.3 1.6 4.8 2.3 1.9 2.4 8.4 5.7 3.1 2.8 2.8 2.0 2.6 1.5 2.7 4.9 2.0 1.4 0.8 1.4 6.9 2.6 1.8 1.9 6.6 3.0 1.8 7.7 8.2 2.8 3.6 3.8 2.1 2.3 5.6 3.3 2.7 1.9 SLC30A8 "ZnT-8, ZNT8" ENSSSCG00000006011 "one2one with ENSG00000164756" "Solute carrier family 30 member 8" Q8IWU4 4 21517638-21555115 "Human disease related genes" "Group enriched" "Detected in some" 4 "brain: 9.7;stomach: 5.6;testis: 22.1" "Low region specificity" "Detected in many" "Cluster 9 - Testis spermatogenesis" "Variable (brain)" 0.1 0.9 3.2 0.0 0.0 0.1 0.3 0.3 0.7 0.1 0.1 0.2 2.0 1.0 0.1 0.0 0.2 1.1 0.4 0.4 1.0 0.3 0.2 0.9 0.9 0.2 0.6 0.2 1.0 1.0 0.3 0.1 0.0 1.4 0.2 1.0 0.2 0.0 0.2 0.6 0.2 0.1 0.1 0.0 0.4 0.0 0.8 0.6 0.5 0.1 0.3 0.8 0.4 0.1 0.5 0.5 2.0 0.1 0.3 0.9 0.0 1.3 0.8 0.5 0.6 0.4 0.7 0.6 0.0 1.2 0.6 0.0 0.0 0.0 0.4 0.3 0.1 2.2 0.3 0.0 4.7 0.3 0.5 0.2 1.5 18.2 0.4 0.1 1.0 0.1 0.2 0.8 0.1 0.2 0.0 7.9 0.3 0.6 SLC5A5 NIS ENSSSCG00000013890 "one2one with ENSG00000105641" "Sodium/iodide cotransporter " Q92911 2 59869155-59885266 "Human disease related genes" "Group enriched" "Detected in some" 4 "choroid plexus: 68.1;stomach: 42.9;thyroid gland: 100.2" "Low region specificity" "Detected in many" "Cluster 64 - Gastrointestinal" "Variable (brain, upper respiratory system)" 4.0 0.2 0.9 0.3 2.1 1.2 1.5 0.0 0.6 2.3 1.4 0.5 335.8 0.6 2.6 0.1 1.0 0.5 6.7 0.0 0.3 1.5 0.1 3.7 4.1 0.3 14.0 0.5 1.5 0.4 0.1 0.2 0.0 2.0 1.4 0.3 0.6 0.1 0.2 0.3 28.4 0.0 0.2 0.3 1.0 0.6 8.5 2.6 1.0 2.0 0.3 3.9 2.0 0.8 0.0 3.0 1.7 2.0 8.9 1.1 1.2 2.4 0.4 0.8 0.3 1.3 0.7 0.4 0.4 0.4 1.0 0.2 2.5 0.2 0.3 0.7 2.2 92.0 79.1 0.2 6.8 16.6 69.0 0.4 2.3 0.4 4.3 3.9 455.6 0.9 1.5 15.1 0.1 0.6 2.5 1.2 1.6 2.8 SLC6A14 ENSSSCG00000022372 "one2one with ENSG00000268104" "Solute carrier family 6 member 14" Q9UN76 X 95482205-95527340 "Human disease related genes" "Tissue enhanced" "Detected in some" "esophagus: 16.5;gallbladder: 23.1;large intestine: 16.9;male glands: 12.2;salivary gland: 12.8;upper respiratory system: 22.5" "Not detected" "Not detected" "Cluster 67 - Gastrointestinal" "Variable (male glands, small intestine)" 0.0 0.0 0.0 0.0 0.1 0.4 2.8 12.1 0.0 13.6 0.0 0.9 0.0 0.0 22.9 7.1 0.0 0.0 0.0 0.0 7.0 0.0 0.2 4.3 0.0 0.0 24.4 0.0 0.3 32.8 0.0 0.0 0.0 0.0 0.6 0.0 1.1 0.0 0.0 0.1 26.8 0.0 0.2 0.0 2.4 0.0 0.0 0.0 0.0 12.9 0.0 0.0 11.3 2.8 0.0 0.1 0.0 0.0 0.2 0.6 0.0 0.0 0.0 0.0 0.0 22.7 0.0 0.0 7.5 0.5 0.0 0.0 2.8 0.0 0.0 0.0 0.0 1.7 1.4 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 8.8 0.2 1.3 20.9 0.3 0.0 0.0 0.0 0.0 0.0 SOD2 ENSSSCG00000040317 "one2many with ENSG00000112096,ENSG00000285441" "Superoxide dismutase " P04179 1 7679352-7691724 "Human disease related genes" "Tissue enhanced" "Detected in all" "heart: 69.9" "Low region specificity" "Detected in all" "Cluster 19 - Housekeeping mitochondrial" "Variable (brain, male glands)" 73.9 83.7 40.2 17.7 20.4 15.3 69.1 39.1 41.3 52.9 44.8 61.2 108.8 51.2 38.4 28.2 16.0 44.7 52.1 11.4 24.2 53.8 10.3 33.9 44.7 2.8 22.2 25.1 27.1 26.0 35.2 21.3 69.0 57.0 14.3 37.7 21.1 8.9 35.3 45.2 26.2 3.5 35.1 18.1 105.3 15.9 63.1 54.3 44.9 53.7 45.1 50.1 40.6 34.8 111.3 12.6 55.8 15.1 44.1 37.0 28.6 65.7 42.1 16.7 33.2 40.4 34.0 46.7 14.3 6.5 60.1 63.6 12.4 5.8 39.4 54.8 7.1 8.2 7.6 16.3 52.9 58.8 68.2 68.9 44.4 40.2 55.9 17.6 17.0 23.4 30.1 53.3 33.9 14.8 14.7 49.8 49.1 62.3 SOX3 PHP ENSSSCG00000022501 "one2one with ENSG00000134595" "SRY-box 3" P41225 X 115019232-115020578 "Human disease related genes" "Group enriched" "Detected in some" 5 "brain: 7.4;lens: 14.3;pituitary gland: 5.7;vagus nerve: 5.3" "Low region specificity" "Detected in many" "Cluster 3 - Brain cellular structure" "Not variable" 0.1 0.4 0.7 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.2 0.1 0.1 0.4 0.0 0.2 0.7 0.7 0.9 0.4 0.1 0.1 0.2 0.1 0.4 0.2 0.3 0.1 0.1 0.5 0.0 0.0 0.0 4.6 0.0 0.4 0.0 0.0 0.2 0.1 0.1 1.8 0.1 0.3 0.0 0.0 0.9 2.3 0.4 0.1 0.3 0.8 0.1 0.1 0.0 0.0 1.0 0.0 0.3 4.1 0.0 0.5 0.5 0.0 0.3 0.0 0.6 0.4 0.1 0.1 1.4 0.1 0.0 0.0 0.1 0.2 0.0 0.1 0.2 0.2 0.6 0.7 1.3 0.1 0.5 0.3 0.9 0.0 0.2 0.0 0.0 0.0 0.0 0.1 3.3 0.7 0.5 1.0 SPRTN "C1orf124, DKFZP547N043, DVC1, Spartan" ENSSSCG00000040087 "one2one with ENSG00000010072" "SprT-like domain-containing protein Spartan " Q9H040 14 59172201-59192225 "Human disease related genes" "Low tissue specificity" "Detected in all" "Low region specificity" "Detected in all" "Cluster 66 - Housekeeping mRNA" "Not variable" 3.4 3.8 2.9 0.8 1.6 2.7 5.5 4.0 2.4 4.3 5.5 4.0 5.1 2.4 4.7 7.5 5.3 2.6 3.2 3.7 5.0 4.9 1.9 4.4 2.2 2.2 5.9 2.5 5.2 2.6 2.1 1.9 2.0 3.4 2.7 2.4 3.4 0.5 3.1 3.8 4.0 0.8 5.7 2.6 5.5 4.7 2.9 2.8 1.8 3.5 2.0 5.3 4.7 4.1 3.7 2.8 3.8 1.2 5.4 4.6 2.2 2.3 1.8 2.6 2.2 4.4 10.4 2.5 2.7 1.7 3.2 2.3 3.3 2.2 3.4 2.1 3.9 2.2 1.8 1.7 2.6 3.3 2.9 2.1 2.3 3.8 2.6 11.0 5.9 5.9 7.1 4.9 3.5 2.6 4.6 2.7 2.8 2.8 SPRY4 ENSSSCG00000036322 "one2one with ENSG00000187678" "Sprouty RTK signaling antagonist 4" Q9C004 2 143877340-143891285 "Human disease related genes" "Low tissue specificity" "Detected in many" "Low region specificity" "Detected in all" "Cluster 81 - Vasculature and connective tissue" "Variable (brain)" 20.1 14.7 7.4 5.0 9.8 7.9 11.0 1.4 4.0 3.5 12.3 3.3 6.1 9.8 3.8 19.7 3.2 7.2 10.3 7.3 3.0 17.0 4.5 5.9 9.4 2.6 4.3 8.6 4.9 5.3 7.3 6.6 6.5 7.6 2.6 9.7 3.7 2.0 4.8 18.8 3.5 0.0 10.2 5.3 18.4 2.9 4.7 8.2 9.9 3.5 8.3 8.1 6.6 8.7 9.2 11.6 5.0 2.7 2.3 14.7 10.4 7.7 10.0 2.3 3.1 4.3 6.7 10.8 1.3 3.5 6.5 9.4 4.1 4.1 8.0 8.3 2.5 5.8 3.0 12.0 7.4 5.9 11.2 10.5 9.4 2.5 9.8 1.7 12.4 7.9 2.4 4.2 4.1 9.1 28.4 8.4 3.6 4.6 STAR "StAR, STARD1" ENSSSCG00000034942 "one2one with ENSG00000147465" "Steroidogenic acute regulatory protein, mitochondrial precursor " P49675 15 48377513-48388326 "Human disease related genes" "Group enriched" "Detected in some" 53 "adrenal gland: 171.0;ovary: 176.9;testis: 78.5" "Not detected" "Not detected" "Cluster 20 - Hormonal" "Not variable" 3.6 937.7 2.6 0.7 1.9 3.2 4.3 1.8 2.4 4.1 4.2 2.8 6.0 2.6 4.3 6.5 3.4 2.4 2.2 3.4 4.3 3.3 2.5 4.1 2.2 3.5 4.8 3.3 6.1 2.5 1.6 1.0 0.9 2.4 2.4 2.2 2.4 0.1 2.7 3.8 4.1 0.5 5.1 1.7 3.5 4.8 2.0 1.9 2.0 2.8 2.0 4.4 3.9 3.7 1212.4 1.9 3.0 0.9 2.6 2.7 1.3 1.7 2.1 3.5 1.9 3.8 11.4 2.4 8.1 2.4 2.6 1.2 2.4 2.1 2.9 2.2 3.5 2.0 2.4 3.2 2.5 2.3 2.1 1.7 2.6 664.1 1.9 11.8 5.1 3.6 5.9 3.4 3.1 2.6 5.1 2.6 2.4 1.9 TAC3 "NKB, NKNB, ZNEUROK1" ENSSSCG00000000418 "one2one with ENSG00000166863" "Neurokinin-B " Q9UHF0 5 22324931-22332815 "Human disease related genes" "Tissue enhanced" "Detected in many" "brain: 26.5;lymphoid tissue: 25.6;small intestine: 18.8;testis: 26.4" "Low region specificity" "Detected in many" "Cluster 5 - Intracellular signalling" "Variable (brain, lymphoid tissue)" 3.1 0.2 13.0 0.3 0.8 0.4 2.3 0.0 15.2 9.4 0.1 0.5 0.6 0.9 10.1 0.0 0.5 1.3 50.5 1.4 6.4 0.7 0.1 2.2 1.5 0.0 5.1 0.0 2.0 3.1 0.0 0.0 0.0 52.9 17.3 1.6 17.4 0.0 0.0 0.3 0.8 0.0 0.3 0.1 3.8 36.4 12.3 2.3 0.6 2.5 0.4 3.1 3.9 2.8 3.1 0.0 7.8 0.0 4.1 0.2 0.2 9.0 0.8 0.1 7.3 3.9 18.3 0.7 0.0 0.3 41.3 0.0 0.2 0.0 0.6 0.5 0.9 2.2 0.8 0.1 3.8 6.9 0.8 0.0 1.8 52.1 10.9 5.6 0.0 0.0 18.9 1.3 0.0 1.8 0.1 4.9 16.1 1.8 TACR3 NK3R ENSSSCG00000009160 "one2one with ENSG00000169836" "Tachykinin receptor 3" P29371 8 117661792-117721591 "Human disease related genes" "Tissue enhanced" "Detected in many" "fallopian tube: 25.0;ovary: 10.9;pituitary gland: 11.8" "Low region specificity" "Detected in many" "Cluster 3 - Brain cellular structure" "Variable (brain)" 0.0 3.6 3.1 0.3 0.1 0.1 0.5 0.1 0.6 0.2 0.4 2.8 0.6 2.1 0.3 3.8 0.7 3.7 4.1 1.9 0.6 2.1 0.3 5.2 2.0 0.8 0.1 0.2 27.8 0.1 0.4 0.1 0.1 6.5 0.2 2.0 0.3 0.0 0.3 2.1 0.1 0.0 0.2 0.0 0.3 0.4 4.0 3.0 1.8 1.7 1.4 1.9 1.1 0.2 9.3 2.2 2.9 0.6 3.5 15.4 0.4 3.7 3.0 0.6 0.9 0.2 11.6 1.6 0.0 0.3 4.2 0.0 0.5 0.0 0.1 1.3 0.4 0.1 0.2 0.0 2.6 9.3 2.2 0.1 1.5 2.1 1.0 0.9 0.1 0.1 0.8 0.2 0.2 0.4 0.4 3.2 2.1 4.0 TBX19 "dj747L4.1, TPIT" ENSSSCG00000006299 "one2one with ENSG00000143178" "T-box 19" O60806 4 82663581-82697813 "Human disease related genes" "Tissue enriched" "Detected in some" 16 "pituitary gland: 44.5" "Not detected" "Not detected" "Cluster 20 - Hormonal" "Not variable" 0.0 0.1 0.2 0.0 0.0 1.5 1.1 0.1 0.3 0.0 0.0 0.2 0.3 0.2 0.2 0.4 0.0 0.2 0.1 0.0 0.1 0.2 0.2 0.4 0.1 0.0 0.7 0.0 0.7 0.2 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.2 0.3 1.6 0.7 0.4 0.2 1.1 0.0 0.1 0.1 0.1 2.1 0.0 0.1 2.6 0.1 0.0 0.6 0.2 0.0 0.1 80.9 0.0 0.1 0.1 0.5 0.1 0.0 0.0 0.1 0.4 0.2 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.2 0.1 0.1 0.2 0.1 0.2 0.0 0.1 0.2 0.0 0.1 0.2 0.1 0.1 4.0 0.3 0.3 0.1 0.3 0.3 0.2 TCF7L2 "TCF-4, TCF4" ENSSSCG00000010638 "one2one with ENSG00000148737" "Transcription factor 7 like 2" Q9NQB0 14 123343756-123545925 "Human disease related genes" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 5 "midbrain: 44.4;pons and medulla: 25.9;thalamus: 40.8" "Cluster 75 - Housekeeping" "Variable (brain, lymphoid tissue)" 177.5 46.1 31.9 46.9 92.4 87.7 84.4 27.3 24.4 183.6 12.8 148.0 47.2 24.5 195.8 93.0 47.2 25.1 32.0 91.9 99.4 99.4 78.4 104.0 23.5 32.2 91.1 145.5 159.4 88.3 31.5 28.6 18.7 38.9 102.4 25.8 83.4 23.4 58.3 109.1 57.9 4.1 83.2 55.4 84.7 27.8 29.4 190.1 22.0 45.3 19.9 31.0 55.0 61.3 61.5 113.2 105.0 37.2 30.1 34.3 63.3 104.8 22.4 46.8 21.6 153.1 35.1 25.6 32.0 54.4 34.0 33.7 67.2 52.0 65.0 22.5 244.4 63.6 78.7 113.5 33.2 40.5 173.1 91.2 23.4 34.4 169.1 10.3 34.9 58.5 32.8 77.4 45.7 90.9 120.1 29.3 32.5 26.9 TG "AITD3, TGN" ENSSSCG00000005948 "one2one with ENSG00000042832" "Thyroglobulin precursor " P01266 4 8158497-8382392 "Human disease related genes" "Tissue enriched" "Detected in some" 965 "thyroid gland: 1006.8" "Not detected" "Not detected" "Cluster 38 - Lung and thyroid development" "Variable (cartilage, lymphoid tissue)" 0.0 0.3 1.0 0.0 0.0 0.0 0.2 0.0 1.6 0.0 0.2 0.0 0.1 0.2 0.1 0.7 1.2 2.0 0.3 0.0 0.0 0.1 0.2 0.0 0.4 1.2 0.4 0.0 0.3 0.9 0.0 1.3 0.0 1.4 0.0 0.3 0.1 0.9 0.0 0.1 0.3 0.0 6.1 0.1 0.2 0.9 1.0 0.7 0.2 0.1 0.2 0.4 0.5 1.8 0.1 0.4 4.7 0.0 0.1 0.0 0.1 1.7 0.2 0.0 0.3 0.1 0.1 0.3 12.6 0.0 1.2 0.1 0.1 0.1 0.9 0.2 0.0 0.0 0.2 0.0 0.9 0.6 0.4 0.4 0.4 13.5 0.6 8.0 34453.9 5.8 3.8 1.4 0.0 0.0 0.4 2.0 0.5 0.2 THRA "AR7, EAR-7.1/EAR-7.2, ERBA, ERBA1, NR1A1, THRA1, THRA2, THRA3" ENSSSCG00000035969 "one2one with ENSG00000126351" "Thyroid hormone receptor alpha " P10827 12 22266099-22296729 "Human disease related genes" "Low tissue specificity" "Detected in all" "Low region specificity" "Detected in all" "Cluster 4 - Brain development" "Variable (lymphoid tissue)" 55.1 26.7 88.4 13.0 20.4 22.4 22.6 17.3 67.7 29.0 55.8 38.1 30.4 69.8 27.9 21.4 74.0 78.7 50.3 49.8 23.5 34.7 26.3 36.4 63.7 10.9 23.3 40.0 54.3 33.8 22.8 16.9 25.7 70.9 20.0 70.8 21.4 4.9 19.3 38.2 17.2 5.0 24.0 13.3 26.9 10.0 53.2 52.8 59.8 12.3 46.9 73.6 13.1 27.7 12.1 29.5 70.3 18.1 27.6 50.0 22.7 51.3 62.4 22.5 49.7 26.4 31.2 67.5 13.5 17.6 74.1 33.8 21.2 16.2 63.3 59.3 14.6 21.3 27.9 21.8 85.9 59.5 46.3 28.9 70.3 6.5 47.8 7.6 32.6 16.2 8.3 26.2 27.3 33.9 56.3 98.3 69.1 47.0 THRB "ERBA-BETA, ERBA2, GRTH, NR1A2, PRTH, THR1, THRB1, THRB2" ENSSSCG00000036033 "one2one with ENSG00000151090" "Thyroid hormone receptor beta" P10828 13 10900718-11360024 "Human disease related genes" "Low tissue specificity" "Detected in many" "Low region specificity" "Detected in all" "Cluster 12 - Metabolic" "Variable (male glands)" 52.8 1.2 33.7 10.0 16.1 9.7 5.4 1.3 17.3 4.5 8.7 11.2 48.3 60.5 5.9 2.9 15.1 27.7 13.0 18.3 11.8 21.1 9.3 3.1 53.6 0.8 15.2 18.5 16.2 15.6 10.5 7.5 6.8 17.0 2.9 52.2 4.6 4.6 9.6 12.1 7.2 15.2 10.6 9.2 6.6 1.7 13.6 15.3 55.5 5.2 39.7 13.5 4.1 10.0 6.0 18.5 17.4 8.3 17.3 81.3 10.3 13.2 60.6 20.6 10.1 9.2 39.5 55.0 7.7 5.6 20.2 8.6 6.6 7.8 13.1 49.2 1.6 1.9 1.8 25.0 46.7 14.3 17.3 12.1 44.5 0.6 16.3 3.1 2.6 8.7 3.2 11.4 12.6 4.1 3.4 33.0 17.8 15.2 TPO TPX ENSSSCG00000033193 "one2one with ENSG00000115705" "Thyroid peroxidase " P07202 3 132384820-132408943 "Human disease related genes" "Tissue enriched" "Detected in some" 185 "thyroid gland: 355.8" "Not detected" "Not detected" "Cluster 38 - Lung and thyroid development" "Variable (male glands)" 0.1 0.3 0.2 0.1 0.0 0.7 0.2 1.3 0.0 0.1 0.2 0.0 2.1 0.0 0.1 21.1 0.0 0.0 0.2 13.8 1.0 0.2 1.0 0.0 0.0 3.2 0.4 0.1 0.3 0.2 0.0 0.1 0.0 0.0 0.4 0.0 0.3 0.0 1.1 0.5 0.2 0.2 0.7 0.4 0.1 0.1 0.1 0.0 0.0 0.4 0.0 0.0 0.2 0.6 0.0 0.1 0.0 0.0 0.1 0.8 0.1 0.0 0.0 0.2 0.0 0.1 0.0 0.0 8.2 5.6 0.0 0.0 0.1 0.1 0.4 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.6 0.0 3.6 4303.4 0.8 0.4 0.3 0.6 2.3 0.0 0.0 0.0 0.3 TRHR ENSSSCG00000040768 "one2one with ENSG00000174417" "Thyrotropin releasing hormone receptor" P34981 4 28436758-28482893 "Human disease related genes" "Tissue enhanced" "Detected in all" "pituitary gland: 24.4" "Low region specificity" "Detected in all" "Cluster 20 - Hormonal" "Variable (brain)" 1.5 1.4 8.4 1.0 0.9 1.9 2.4 1.4 1.7 1.8 3.6 1.8 3.1 2.1 2.0 4.1 2.4 8.5 3.5 2.5 2.0 2.8 2.4 2.3 1.8 1.9 3.4 0.9 3.5 2.0 1.0 0.7 0.6 4.2 1.0 2.1 1.2 0.2 1.6 2.5 2.5 0.3 2.8 1.4 2.6 1.9 4.1 2.5 1.5 1.9 1.3 5.4 2.1 2.0 1.3 1.8 3.9 0.7 2.2 26.7 1.2 3.5 1.6 2.4 1.1 1.7 7.0 2.1 1.0 1.8 3.1 1.2 1.6 1.1 1.9 1.5 1.2 1.1 0.7 0.9 2.4 8.1 1.7 1.4 2.0 2.4 1.5 4.5 4.1 1.8 2.4 2.7 2.0 1.5 3.1 7.1 2.8 7.4 TSHB ENSSSCG00000006749 "one2one with ENSG00000134200" "Thyrotropin subunit beta precursor " P01222 4 105553076-105554015 "Human disease related genes" "Tissue enriched" "Detected in single" 320 "pituitary gland: 183.3" "Not detected" "Not detected" "Cluster 20 - Hormonal" "Not variable" 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.4 0.2 0.5 0.1 0.0 0.0 0.4 0.3 0.1 0.1 0.0 0.0 0.4 0.3 0.6 0.1 0.0 0.8 0.2 0.2 0.1 0.1 1.0 0.1 0.3 0.0 0.0 0.1 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.5 0.3 0.0 0.2 0.3 0.0 0.0 0.0 0.1 0.6 0.0 0.3 1371.9 0.0 0.3 0.3 0.0 0.1 0.1 0.1 0.5 0.0 0.0 0.4 0.0 0.0 0.0 2.7 0.7 0.1 0.1 0.0 0.0 0.2 0.1 0.6 0.0 0.6 2.6 0.3 0.1 0.2 0.0 0.0 0.5 0.0 0.4 0.0 0.2 0.1 0.0 TSHR LGR3 ENSSSCG00000031771 "one2one with ENSG00000165409" "Thyrotropin receptor precursor " P16473 7 103768260-103926287 "Human disease related genes" "Tissue enhanced" "Detected in all" "thyroid gland: 48.6" "Low region specificity" "Detected in all" "Cluster 44 - Housekeeping" "Variable (male glands)" 14.8 8.2 17.4 2.8 5.4 7.7 11.9 2.2 13.0 11.1 27.3 11.1 23.3 17.1 12.3 18.9 15.5 12.3 7.9 10.8 11.0 15.9 6.4 12.9 14.0 6.0 15.7 12.7 14.4 8.5 5.1 3.6 3.8 14.1 5.5 16.5 5.6 0.7 6.2 13.5 11.2 1.8 12.4 5.3 14.4 8.7 7.4 8.5 10.9 6.7 11.9 31.3 9.1 9.4 7.8 7.5 13.2 2.6 19.6 22.3 5.0 6.6 12.8 8.2 8.0 10.5 51.3 16.0 4.0 8.3 13.3 8.6 6.1 7.2 9.2 11.0 7.1 4.0 2.2 9.0 14.9 9.6 7.2 8.4 15.1 14.9 7.1 27.5 80.7 9.3 12.2 12.0 8.9 7.4 17.5 13.7 12.7 6.6 TXNRD2 "TR, TR3, TRXR2" ENSSSCG00000010131 "one2one with ENSG00000184470" "Thioredoxin reductase 2, mitochondrial " Q9NNW7 14 51354178-51385353 "Human disease related genes" "Low tissue specificity" "Detected in all" "Low region specificity" "Detected in all" "Cluster 66 - Housekeeping mRNA" "Not variable" 7.1 9.4 6.2 1.5 4.2 8.2 5.5 5.9 5.8 11.1 7.1 7.5 10.6 6.9 10.6 13.8 6.2 6.4 6.7 6.4 10.1 9.1 5.1 9.0 6.3 9.2 8.8 5.0 8.8 9.2 4.6 2.8 4.2 7.1 5.8 6.3 6.2 0.9 7.2 9.7 8.4 0.8 7.9 3.8 4.8 8.7 6.5 6.6 6.5 4.8 6.4 7.1 7.4 10.1 6.5 7.0 7.3 2.6 4.9 6.1 2.4 6.1 6.1 9.0 4.9 9.3 5.2 6.6 4.2 6.1 6.5 3.8 3.9 5.6 6.5 7.4 6.4 6.0 6.5 3.9 7.1 7.1 7.9 5.8 6.8 3.4 7.0 7.3 10.8 6.4 9.1 6.3 7.6 8.6 8.3 7.5 5.9 6.0 UCP2 "BMIQ4, SLC25A8" ENSSSCG00000014833 "one2one with ENSG00000175567" "Mitochondrial uncoupling protein 2 " P55851 9 8358559-8364552 "Human disease related genes" "Tissue enhanced" "Detected in many" "lens: 49.1;lung: 55.0;lymphoid tissue: 69.1;upper respiratory system: 61.4" "Low region specificity" "Detected in all" "Cluster 79 - Lymphoid myeloid" "Variable (brain, cartilage, lymphoid tissue, upper respiratory system)" 38.1 21.6 9.3 12.8 30.3 4.2 134.9 1.3 21.9 109.5 19.9 2.7 17.3 7.7 113.6 4.7 8.9 12.3 13.8 24.0 49.6 44.0 5.7 11.3 5.7 2.2 51.6 12.1 14.8 39.2 6.2 4.6 3.3 38.8 47.7 7.4 82.4 0.3 7.7 12.8 26.1 50.5 27.0 4.1 256.7 203.9 15.4 20.9 6.2 58.3 4.9 14.6 246.8 25.5 100.5 7.1 25.8 3.5 22.2 11.6 13.3 36.5 6.1 1.8 12.9 96.0 10.3 8.7 2.0 1.7 27.3 3.6 6.1 11.9 13.0 6.1 136.1 23.3 49.8 10.7 14.6 17.0 26.4 48.8 6.5 7.8 36.1 57.7 9.1 17.8 285.5 55.1 3.5 6.0 8.5 10.0 19.3 7.7 UCP3 SLC25A9 ENSSSCG00000014834 "one2one with ENSG00000175564" "Mitochondrial uncoupling protein 3 " P55916 9 8379085-8386377 "Human disease related genes" "Group enriched" "Detected in all" 6 "adipose tissue: 54.9;aorta: 34.4;bone marrow: 44.4;large intestine: 20.2;skeletal muscle: 57.0" "Low region specificity" "Detected in many" "Cluster 81 - Vasculature and connective tissue" "Variable (large intestine)" 39.3 3.2 4.9 31.4 78.3 4.4 7.5 1.8 4.0 57.8 8.7 4.6 8.9 4.8 55.5 8.6 5.8 3.8 3.1 5.2 4.2 7.7 6.2 4.7 3.9 3.2 7.5 68.3 7.1 4.7 3.0 1.6 2.1 3.9 2.1 5.0 2.4 0.5 3.0 5.4 5.9 0.8 16.2 2.1 6.9 4.2 3.3 2.4 3.5 3.5 3.1 8.7 4.3 8.3 2.7 3.7 4.6 1.4 5.6 5.9 11.4 2.3 3.6 5.5 2.5 13.5 12.7 4.6 1.8 4.9 3.8 73.9 8.8 2.9 4.0 3.5 3.1 2.2 2.9 76.7 4.2 3.4 2.5 7.6 4.4 5.2 2.4 12.1 7.5 6.7 5.7 7.6 7.2 3.4 8.6 3.9 3.9 2.8 USP8 "HumORF8, KIAA0055, SPG59, UBPY" ENSSSCG00000004639 "one2one with ENSG00000138592" "Ubiquitin specific peptidase 8" P40818 1 121306032-121376122 "Human disease related genes" "Low tissue specificity" "Detected in all" "Low region specificity" "Detected in all" "Cluster 10 - Housekeeping transcription" "Not variable" 29.3 21.8 31.7 8.6 24.1 18.8 30.3 35.7 30.2 30.0 52.9 49.5 35.6 32.4 33.9 21.7 39.6 38.2 39.0 36.2 24.2 34.4 10.9 45.0 30.9 29.2 29.7 17.5 40.8 31.4 10.8 8.8 8.4 40.3 23.0 25.8 26.6 4.0 21.4 40.8 19.2 11.4 25.2 15.0 40.0 34.8 37.8 36.7 26.7 18.1 29.6 44.6 25.6 29.2 28.6 22.4 42.0 7.2 57.2 64.0 12.2 37.3 27.5 18.3 27.8 36.7 49.6 30.0 19.5 21.8 39.0 10.5 16.8 18.1 41.5 32.6 34.3 12.0 12.3 13.4 34.6 39.4 41.3 17.2 31.3 28.6 35.1 66.6 48.2 26.5 43.8 25.7 16.6 30.1 39.9 35.9 32.6 36.7 VEGFA "VEGF, VEGF-A, VPF" ENSSSCG00000001695 "one2one with ENSG00000112715" "Vascular endothelial growth factor A precursor " P15692 7 38746055-38762342 "Human disease related genes" "Tissue enhanced" "Detected in all" "thyroid gland: 94.9" "Low region specificity" "Detected in all" "Cluster 71 - Housekeeping regulation" "Variable (cartilage, male glands)" 65.9 119.4 14.3 18.5 62.1 21.6 126.7 48.3 11.9 24.4 16.4 31.7 46.0 16.8 21.8 15.5 12.1 13.0 15.2 21.1 32.2 21.6 18.9 32.4 14.8 18.2 35.0 62.0 23.1 133.7 49.7 32.7 54.2 15.1 20.8 15.7 23.3 42.1 106.7 148.0 58.0 15.0 49.4 89.9 129.1 18.4 17.4 16.0 15.7 32.9 14.1 17.0 40.6 65.3 53.9 27.2 16.6 13.0 22.0 20.7 37.2 14.0 14.8 172.8 10.1 15.7 41.8 16.0 91.1 40.5 13.9 117.0 22.6 29.2 16.3 17.5 13.8 34.0 38.9 51.5 14.3 14.6 16.8 56.6 16.3 12.1 14.6 7.9 521.5 57.0 15.5 63.9 174.7 98.8 30.8 14.2 12.9 16.2 WDR11 "BRWD2, DR11, FLJ10506, HH14, KIAA1351, SRI1, WDR15" ENSSSCG00000010692 "one2one with ENSG00000120008" "WD repeat domain 11" Q9BZH6 14 130619107-130673773 "Human disease related genes" "Low tissue specificity" "Detected in all" "Low region specificity" "Detected in all" "Cluster 10 - Housekeeping transcription" "Not variable" 17.4 16.6 21.2 3.9 9.7 13.0 14.4 19.3 16.7 20.0 38.6 19.0 29.3 20.0 20.7 24.0 36.7 24.1 31.3 14.2 20.7 24.5 9.7 39.8 18.8 12.8 18.9 11.1 24.3 14.7 5.6 5.0 5.1 32.8 8.4 17.8 11.1 2.3 16.0 23.1 16.6 4.9 21.0 11.2 16.1 15.3 27.8 28.7 16.9 14.3 16.6 29.4 16.9 16.0 16.2 10.6 31.0 3.6 30.2 37.9 4.8 26.6 17.2 10.8 15.8 17.6 32.6 19.3 7.6 13.7 27.3 5.1 11.6 10.4 14.2 20.0 19.6 12.2 6.7 9.2 26.4 29.0 27.5 12.4 19.8 21.6 27.0 24.4 28.3 18.3 20.1 19.3 7.6 13.7 20.1 24.6 22.0 27.9 WFS1 "DFNA14, DFNA38, DFNA6, DIDMOAD, WFS" ENSSSCG00000032452 "one2one with ENSG00000109501" "Wolframin ER transmembrane glycoprotein" O76024 8 4363486-4379234 "Human disease related genes" "Tissue enriched" "Detected in all" 5 "brain: 93.7" "Low region specificity" "Detected in all" "Cluster 3 - Brain cellular structure" "Variable (brain, lymphoid tissue, male glands)" 19.2 21.2 116.5 6.2 11.1 17.7 18.6 3.6 391.9 13.5 69.5 29.2 108.7 86.8 13.0 40.2 43.6 79.2 133.2 38.8 9.2 16.1 17.3 31.5 96.0 15.0 7.0 10.6 41.8 64.8 13.0 8.0 13.0 72.5 9.0 94.6 11.6 1.5 8.3 27.1 14.6 3.4 11.5 11.4 23.6 4.1 120.8 108.3 77.6 16.4 60.2 77.8 18.9 11.6 83.9 23.8 77.3 4.1 89.4 62.7 16.9 77.9 87.6 13.2 134.8 15.2 27.9 79.3 6.4 9.4 323.6 3.6 8.9 4.6 53.9 65.9 15.5 10.2 12.7 11.8 115.5 108.4 94.1 11.4 109.8 17.0 91.1 19.2 20.4 11.6 4.8 18.3 11.7 21.0 73.6 81.9 412.7 189.4 WRN "RECQ3, RECQL2" ENSSSCG00000015840 "one2one with ENSG00000165392" "Werner syndrome RecQ like helicase" Q14191 15 53966973-54094997 "Human disease related genes" "Low tissue specificity" "Detected in all" "Low region specificity" "Detected in all" "Cluster 44 - Housekeeping" "Not variable" 8.7 8.2 15.1 2.9 6.3 9.8 12.8 12.5 11.1 12.8 23.6 15.4 24.5 13.5 14.6 20.5 16.2 11.8 11.1 12.0 14.8 18.9 8.1 15.0 11.8 7.9 18.4 6.2 17.5 9.6 5.2 3.9 3.6 13.8 7.1 12.5 8.4 1.5 8.0 14.2 12.6 3.8 15.7 16.6 14.1 12.9 10.5 9.8 9.8 9.0 9.7 25.9 12.3 12.1 11.5 9.2 14.1 3.2 25.5 21.8 5.3 9.5 10.2 8.3 8.1 12.5 39.1 12.7 5.5 7.6 12.7 5.9 11.5 8.3 11.3 9.7 9.2 6.5 3.5 5.0 13.7 12.0 9.8 7.2 12.2 10.7 8.9 32.0 18.0 13.1 17.7 12.2 7.2 9.8 18.5 13.3 11.7 9.6 ZFP57 "bA145L22, bA145L22.2, C6orf40, ZNF698" ENSSSCG00000001247 "one2one with ENSG00000204644" "Zinc finger protein 57 homolog " Q9NU63 7 22607420-22612064 "Human disease related genes" "Tissue enriched" "Detected in some" 20 "brain: 105.9" "Low region specificity" "Detected in all" "Cluster 3 - Brain cellular structure" "Variable (brain, lymphoid tissue)" 2.7 1.5 65.3 0.4 0.9 7.0 1.0 1.2 46.5 0.9 22.6 2.5 2.1 43.4 1.3 2.4 525.1 95.6 156.2 12.7 1.7 2.2 2.0 1.6 31.3 14.8 4.3 1.5 2.8 1.7 1.3 0.7 1.2 119.3 2.0 50.9 1.3 0.2 1.6 2.5 7.0 0.5 1.8 1.4 1.0 1.5 170.8 152.0 43.3 2.6 50.3 53.1 3.1 1.5 0.6 2.1 150.6 1.4 4.8 3.7 1.0 108.4 36.9 0.7 119.7 1.2 5.2 62.7 2.3 1.0 105.0 1.6 2.9 3.8 2.6 58.3 3.1 1.0 1.2 1.6 45.1 210.1 129.2 1.7 36.4 10.6 138.7 1.1 3.8 1.4 1.7 4.0 0.5 1.5 9.3 71.8 140.6 145.9