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Human disease related genes
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UMAP gene cluster
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Keyword
Chromosome
1
2
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6
7
8
9
10
11
12
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MT
Unmapped
X
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External id
Variability
Variable
Not variable
Tissue
Any
Adipose tissue
Brain
Cartilage
Heart
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Lymphoid tissue
Male glands
Mesothelial tissue
Mouth
Skin
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Stomach 1
Upper respiratory system
Cluster
1 - Brain neurotransmission
2 - Brain neurotransmission
3 - Brain cellular structure
4 - Brain development
5 - Intracellular signalling
6 - Brain uncharacterized
7 - Retinal
8 - Neurohormonal
9 - Testis spermatogenesis
10 - Housekeeping transcription
11 - Testis uncharacterized
12 - Metabolic
13 - Testis sperm
14 - Low abundant uncharacterized
15 - Testis uncharacterized
16 - Aorta uncharacterized
17 - Cilium structure
18 - Low abundant uncharacterized
19 - Housekeeping mitochondrial
20 - Hormonal
21 - Low abundant uncharacterized
22 - Housekeeping transcription
23 - Cilium structure
24 - Low abundant uncharacterized
25 - Low abundant uncharacterized
26 - Low abundant uncharacterized
27 - Low abundant uncharacterized
28 - Housekeeping mitochondrial translation
29 - Male tissue bacterial defense
30 - Housekeeping structural
31 - Housekeeping uncharacterized
32 - Transport
33 - Lens
34 - Prostate uncharacterized
35 - Low abundant uncharacterized
36 - Receptors uncharacterized
37 - Olfactory bulb
38 - Lung and thyroid development
39 - Kidney transport
40 - Testis
41 - Low abundant uncharacterized
42 - Low abundant uncharacterized
43 - Breast uncharacterized
44 - Housekeeping
45 - Thymus uncharacterized
46 - Skeletal muscle contraction
47 - Spleen uncharacterized
48 - Low abundant uncharacterized
49 - Heart contraction
50 - Muscle contraction
51 - Liver and kidney
52 - Housekeeping
53 - Housekeeping mitochondrial
54 - Interferons
55 - Low abundant uncharacterized
56 - Low abundant uncharacterized
57 - Skin
58 - Immune cells
59 - Squamous epithelium
60 - Not detected
61 - Enzymes and secretion
62 - Squamous epithelium
63 - Small intestine
64 - Gastrointestinal
65 - Epithelium
66 - Housekeeping mRNA
67 - Gastrointestinal
68 - Housekeeping protein processing
69 - Housekeeping
70 - Housekeeping
71 - Housekeeping regulation
72 - Digestive and respiratory defense
73 - Housekeeping cell cycle
74 - Extracellular matrix
75 - Housekeeping
76 - Housekeeping regulation
77 - Housekeeping defense
78 - Lymphoid T cells
79 - Lymphoid myeloid
80 - Heart uncharacterized
81 - Vasculature and connective tissue
82 - Lymphoid B cell
83 - Not detected
84 - Epithelium transcription regulation
Tissue group
Any
Adipose tissue
Adrenal gland
Aorta
Bone marrow
Brain
Breast
Cartilage
Cervix
Choroid plexus
Cornea
Ductus deferens
Dura mater
Endometrium
Epididymis
Esophagus
Fallopian tube
Gallbladder
Heart
Kidney
Large intestine
Lens
Liver
Lung
Lymphoid tissue
Male glands
Mesothelial tissue
Mouth
Ovary
Penis
Pineal gland
Pituitary gland
Retina
Salivary gland
Skeletal muscle
Skin
Small intestine
Smooth muscle
Stomach
Synovial tissue
Testis
Thyroid gland
Upper respiratory system
Urinary bladder
Vagus nerve
Category
Tissue enriched
Group enriched
Tissue enhanced
Low tissue specificity
Not detected
Detected in all
Detected in many
Detected in some
Detected in single
Is highest expressed
Brain region
Any
Amygdala
Basal ganglia
Cerebellum
Cerebral cortex
Corpus callosum
Hippocampal formation
Hypothalamus
Midbrain
Olfactory region
Pituitary gland
Pons and medulla
Retina
Spinal cord
Thalamus
Category
Region enriched
Group enriched
Region enhanced
Low region specificity
Not detected
Detected in all
Detected in many
Detected in some
Detected in single
Is highest expressed
Column
Gene
Position
Tissue specific score
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THE PIG PROTEOME
THE PIG ATLAS
TISSUE SPECIFIC PROTEOME
UMAP GENE CLUSTERING
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15100 GENES FOUND
Gene
Gene
i
Gene name, if available.
Gene synonym (Human ortholog)
Ensembl gene id
Ensembl gene id (Proteincoding human ortholog)
Gene description
Uniprot accession (Human ortholog)
Chromosome
Chromosome position
Related human disease
RNA category pig
RNA pig tissue group specificity
RNA pig tissue group distribution
RNA pig tissue group specificity score
RNA pig tissue group specific NX
RNA pig brain regional specificity
RNA pig brain regional distribution
RNA pig brain regional specificity score
RNA pig brain regional specific pTPM
Annotation
UMAP cluster
Within tissue variation
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Select data columns:
Gene
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Gene
i
Gene name, if available.
Gene synonym (Human ortholog)
Ensembl gene id
Ensembl gene id (Proteincoding human ortholog)
Gene description
Uniprot accession (Human ortholog)
Chromosome
Chromosome position
Related human disease
RNA category pig
Expand
RNA pig tissue group specificity
RNA pig tissue group distribution
RNA pig tissue group specificity score
RNA pig tissue group specific NX
RNA pig brain regional specificity
RNA pig brain regional distribution
RNA pig brain regional specificity score
RNA pig brain regional specific pTPM
Annotation
Expand
UMAP cluster
Within tissue variation
Pig Tissue RNA
Expand
Abdominal adipose tissue [NX]
Adrenal gland [NX]
Amygdala [NX]
Aorta [NX]
Bone marrow [NX]
Breast [NX]
Bronchus [NX]
Bulbourethral gland [NX]
Caudate [NX]
Cecum [NX]
Cerebellum [NX]
Cervix [NX]
Choroid plexus [NX]
Cingulate cortex [NX]
Colon [NX]
Cornea [NX]
Corpus callosum [NX]
Dorsal hippocampus [NX]
Dorsal spinal cord [NX]
Ductus deferens [NX]
Duodenum [NX]
Dura mater [NX]
Ear cartilage [NX]
Endometrium 1 [NX]
Entorhinal cortex [NX]
Epididymis [NX]
Esophagus [NX]
Facial adipose tissue [NX]
Fallopian tube [NX]
Gallbladder [NX]
Heart atrium [NX]
Heart valve [NX]
Heart wall [NX]
Hypothalamus [NX]
Ileum [NX]
Insular cortex [NX]
Jejunum [NX]
Joint cartilage [NX]
Kidney (cortex) [NX]
Kidney (medulla) [NX]
Larynx [NX]
Lens [NX]
Lip [NX]
Liver [NX]
Lung [NX]
Lymph node [NX]
Medulla [NX]
Midbrain [NX]
Motor cortex [NX]
Nasopharynx epithelium [NX]
Occipital cortex [NX]
Olfactory bulb [NX]
Olfactory epithelium [NX]
Oral mucosa [NX]
Ovary [NX]
Penis [NX]
Periaqueductal gray [NX]
Peritoneum [NX]
Pineal gland [NX]
Pituitary gland [NX]
Pleura [NX]
Pons [NX]
Prefrontal cortex [NX]
Prostate [NX]
Putamen [NX]
Rectum [NX]
Retina [NX]
Retrosplenial cortex [NX]
Salivary gland [NX]
Seminal vesicle [NX]
Septum [NX]
Skeletal muscle [NX]
Skin (back) [NX]
Skin (groin) [NX]
Smooth muscle (intestine) [NX]
Somatosensory cortex [NX]
Spleen [NX]
Stomach (lower) [NX]
Stomach (upper) [NX]
Subcutaneous adipose tissue [NX]
Subiculum [NX]
Substantia nigra [NX]
Superior colliculi [NX]
Synovial tissue [NX]
Temporal cortex [NX]
Testis [NX]
Thalamus [NX]
Thymus [NX]
Thyroid gland [NX]
Tongue [NX]
Tonsil [NX]
Trachea [NX]
Urethral gland [NX]
Urinary bladder [NX]
Vagus nerve [NX]
Ventral hippocampus [NX]
Ventral pallidum [NX]
Ventral spinal cord [NX]
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Gene
i
Gene name, if available.
Ensembl
x
Human ortholog
x
Gene description
x
RNA pig tissue group specificity
x
RNA pig tissue group distribution
x
RNA pig tissue group specific NX
x
SHARPIN
ENSSSCG00000005914
ENSG00000179526
SHANK associated RH domain interactor
Low tissue specificity
Detected in all
SHAS2
ENSSSCG00000005992
ENSG00000170961
Hyaluronan synthase 2
Tissue enhanced
Detected in all
ovary:
33.1
SHC1
ENSSSCG00000006539
ENSG00000160691
SHC adaptor protein 1
Low tissue specificity
Detected in all
SHCBP1L
ENSSSCG00000026983
ENSG00000157060
SHC binding and spindle associated 1 like
Tissue enriched
Detected in many
testis:
77.2
SHE
ENSSSCG00000006547
ENSG00000169291
Src homology 2 domain containing E
Low tissue specificity
Detected in many
SHISA4
ENSSSCG00000031981
ENSG00000198892
Shisa family member 4
Tissue enhanced
Detected in many
brain:
43.2
skeletal muscle:
124.2
SHISA5
ENSSSCG00000011357
ENSG00000164054
Shisa family member 5
Tissue enhanced
Detected in all
adrenal gland:
86.1
SHISA9
ENSSSCG00000032878
ENSG00000237515
Shisa family member 9
Tissue enriched
Detected in some
brain:
51.9
SHISAL2B
ENSSSCG00000024514
ENSG00000145642
Shisa like 2B
Tissue enhanced
Detected in many
brain:
24.9
skin:
12.0
SHKBP1
ENSSSCG00000033836
ENSG00000160410
SH3KBP1 binding protein 1
Low tissue specificity
Detected in all
SHMT2
ENSSSCG00000037077
ENSG00000182199
Serine hydroxymethyltransferase 2
Tissue enhanced
Detected in all
cartilage:
56.8
SHOC2
ENSSSCG00000010628
ENSG00000108061
SHOC2, leucine rich repeat scaffold protein
Low tissue specificity
Detected in all
SHPRH
ENSSSCG00000004120
ENSG00000146414
SNF2 histone linker PHD RING helicase
Low tissue specificity
Detected in all
SHQ1
ENSSSCG00000011518
ENSG00000144736
SHQ1, H/ACA ribonucleoprotein assembly factor
Low tissue specificity
Detected in all
SHROOM1
ENSSSCG00000014287
ENSG00000164403
Shroom family member 1
Low tissue specificity
Detected in all
SHROOM3
ENSSSCG00000008984
ENSG00000138771
Shroom family member 3
Tissue enhanced
Detected in many
ductus deferens:
63.6
salivary gland:
51.6
stomach:
71.7
SHROOM4
ENSSSCG00000012309
ENSG00000158352
Shroom family member 4
Low tissue specificity
Detected in many
SHTN1
ENSSSCG00000010665
ENSG00000187164
Shootin 1
Tissue enhanced
Detected in many
brain:
83.8
SI
ENSSSCG00000011735
ENSG00000090402
Sucrase-isomaltase
Tissue enriched
Detected in some
small intestine:
104.8
SIAE
ENSSSCG00000015196
ENSG00000110013
Sialic acid acetylesterase
Low tissue specificity
Detected in all
SIAH1
ENSSSCG00000037263
ENSG00000196470
Siah E3 ubiquitin protein ligase 1
Low tissue specificity
Detected in all
SIAH2
ENSSSCG00000031388
ENSG00000181788
Siah E3 ubiquitin protein ligase 2
Low tissue specificity
Detected in all
SIDT1
ENSSSCG00000024429
ENSG00000072858
SID1 transmembrane family member 1
Tissue enhanced
Detected in many
stomach:
25.8
SIDT2
ENSSSCG00000015074
ENSG00000149577
SID1 transmembrane family member 2
Low tissue specificity
Detected in all
SIGIRR
ENSSSCG00000024389
ENSG00000185187
Single Ig IL-1-related receptor
Low tissue specificity
Detected in many
SIGLEC1
ENSSSCG00000007146
ENSG00000088827
Sialoadhesin precursor
Low tissue specificity
Detected in all
SIGLEC15
ENSSSCG00000004493
ENSG00000197046
Sialic acid binding Ig like lectin 15
Tissue enhanced
Detected in all
dura mater:
21.5
SIGMAR1
ENSSSCG00000037000
ENSG00000147955
Sigma non-opioid intracellular receptor 1
Tissue enhanced
Detected in all
liver:
77.8
SIK2
ENSSSCG00000032941
ENSG00000170145
Salt inducible kinase 2
Tissue enhanced
Detected in all
adipose tissue:
63.3
SIK3
ENSSSCG00000015071
ENSG00000160584
SIK family kinase 3
Low tissue specificity
Detected in all
SIKE1
ENSSSCG00000006751
ENSG00000052723
Suppressor of IKBKE 1
Low tissue specificity
Detected in all
SIL1
ENSSSCG00000024189
ENSG00000120725
SIL1 nucleotide exchange factor
Low tissue specificity
Detected in all
SIMC1
ENSSSCG00000014062
ENSG00000170085
SUMO interacting motifs containing 1
Tissue enhanced
Detected in all
lens:
52.0
SIN3A
ENSSSCG00000001880
ENSG00000169375
SIN3 transcription regulator family member A
Low tissue specificity
Detected in all
SIN3B
ENSSSCG00000013867
ENSG00000127511
SIN3 transcription regulator family member B
Low tissue specificity
Detected in all
SIPA1
ENSSSCG00000012982
ENSG00000213445
Signal-induced proliferation-associated 1
Tissue enhanced
Detected in many
lymphoid tissue:
53.6
SIPA1L1
ENSSSCG00000002332
ENSG00000197555
Signal induced proliferation associated 1 like 1
Low tissue specificity
Detected in all
SIPA1L2
ENSSSCG00000010169
ENSG00000116991
Signal induced proliferation associated 1 like 2
Low tissue specificity
Detected in many
SIPA1L3
ENSSSCG00000002950
ENSG00000105738
Signal induced proliferation associated 1 like 3
Tissue enhanced
Detected in all
male glands:
62.5
stomach:
62.3
SIRPB2
ENSSSCG00000007185
ENSG00000196209
Signal regulatory protein beta 2
Tissue enhanced
Detected in all
lymphoid tissue:
24.2
SIRT1
ENSSSCG00000010235
ENSG00000096717
Sirtuin 1
Low tissue specificity
Detected in all
SIRT2
ENSSSCG00000026794
ENSG00000068903
NAD-dependent protein deacetylase sirtuin-2
Tissue enhanced
Detected in all
brain:
91.8
SIRT3
ENSSSCG00000014558
ENSG00000142082
NAD-dependent protein deacetylase sirtuin-3, mitochondrial precursor
Low tissue specificity
Detected in all
SIRT4
ENSSSCG00000009901
ENSG00000089163
NAD-dependent protein lipoamidase sirtuin-4, mitochondrial
Low tissue specificity
Detected in all
SIRT5
ENSSSCG00000031129
ENSG00000124523
NAD-dependent protein deacylase sirtuin-5, mitochondrial
Low tissue specificity
Detected in all
SIRT6
ENSSSCG00000013496
ENSG00000077463
NAD-dependent protein deacetylase sirtuin-6
Low tissue specificity
Detected in all
SIRT7
ENSSSCG00000034695
ENSG00000187531
NAD-dependent protein deacetylase sirtuin-7
Tissue enhanced
Detected in all
stomach:
45.2
SIX3
ENSSSCG00000039283
ENSG00000138083
SIX homeobox 3
Group enriched
Detected in some
brain:
16.8
lens:
51.1
pituitary gland:
42.1
retina:
28.4
upper respiratory system:
33.6
SIX4
ENSSSCG00000005089
ENSG00000100625
Homeobox protein SIX4
Tissue enhanced
Detected in many
male glands:
28.3
salivary gland:
30.7
skeletal muscle:
26.9
upper respiratory system:
22.6
SIX5
ENSSSCG00000035791
ENSG00000177045
SIX homeobox 5
Low tissue specificity
Detected in many
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